Researchers at Bar-Ilan University used a novel motion simulator to study rodent navigation in dark environments. The study found that rats use airflow cues, combined with their sense of balance, to enhance their self-motion perception. This breakthrough sheds light on the mechanisms behind sensory processing and brain function.
Researchers have developed a novel 'simulating learning methodology' (SLeM) framework to automate machine learning. This approach transforms traditional human-defined learning processes into an automated process, enabling ML tools to design and optimize fundamental components.
A Cleveland Clinic study found delayed time to treatment with oral antimyeloma medications, particularly among Black and elderly patients. Independent predictors identified include barriers to timely medication prescription fill.
A recent meta-analysis found that the Messinian Salinity Crisis significantly altered Mediterranean biodiversity, with 66.8% dissimilarity between species before and after the crisis. The study also showed that only a few endemic species survived the event, while new species were introduced following the reconnection to the Atlantic.
The University of Texas at Arlington is piloting a program that allows community college students from Dallas College's North Lake campus to participate in paid research opportunities with faculty mentors. Students receive $6,000 for their time and effort and have the chance to advance their STEM education and careers.
Researchers at the University of Hawaii have developed a new gene editing technology that can efficiently deliver healthy genes to the body. This method addresses limitations of current methods and has shown success rates of up to 96%, potentially leading to faster and more affordable treatments for various genetic diseases.
A research study by UCD and McGill University in collaboration with NASA found that spaceflight profoundly alters the gut microbiome, leading to immune and metabolic dysfunction. The study offers new insights into how these changes may affect astronaut health during extended missions.
Charging lithium-ion batteries at high currents just before they leave the factory increases average lifespan by 50% and decreases initial charging time from 10 hours to 20 minutes. Researchers used machine learning to pinpoint changes in battery electrodes that account for this increase in performance.
A study published in JAMA found that inhaler prescriptions filled by Medicare beneficiaries in 2022 resulted in approximately 1.15 million metric tons of carbon dioxide equivalent emissions. Metered-dose inhalers, particularly those using short-acting β-agonist medications, accounted for nearly all inhaler-related emissions.
Researchers tested suvorexant's effectiveness in reducing delirium in older adults, with findings suggesting it may benefit hyperactive and mixed subtypes but not hypoactive delirium. The study included 203 Japanese adults aged 65-90 years hospitalized for sudden illness or scheduled surgery.
A team of researchers used ALMA to study the earliest known pair of close quasars, discovering that they are merging and will form a super-bright monster galaxy. The merger is expected to trigger a rapid increase in star formation, creating a 'starburst' effect.
Researchers found that white-browed sparrow weavers in the Kalahari Desert build nests reflecting group-specific cultural traditions. The birds' social learning and preferences drive these architectural styles, which remain consistent even when they move between groups.
Researchers discovered CBL as a promising biomarker for AD, regulated by HOXB13 and post-transcriptionally modulated by miR-1321. This regulatory axis was established using high-throughput RNA expression data and verified in human specimens.
Researchers at University of Córdoba identify a new molecular pathway modulating astrocytes and kisspeptin activity to regulate reproductive functions. The study reveals the role of diet in modulating reproductive alterations associated with obesity.
Researchers found that plasmonic excitation of Cu nanowires dramatically enhances the nitrate reduction reaction (NO3RR) performance. The current density is enhanced by a factor of 3 under simulated solar irradiation, and the faradaic efficiency reaches nearly 100%.
Researchers found immersive VR training significantly improves life skills in adults with intellectual disability, outperforming non-immersive methods. The study showed that VR headsets enable participants to learn practical life skills faster and retain them longer.
Researchers at Tokyo Medical and Dental University discovered the role of A20 in suppressing chronic hepatitis by inhibiting the DCLK1-JNK pathway-dependent chemokines. In mice lacking A20 expression, hepatic stellate cells displayed spontaneous inflammation and increased chemokine levels.
Researchers found that Copaxone improves damaged mouse hearts by reducing inflammation and increasing blood supply to other organs. The drug also protects cardiac muscle cells from damage and promotes new blood vessel growth.
A study found that children as young as six can contribute to group projects when there are clear and common goals. The researchers used a game where children worked together to fill a pool with water, with benefits for the whole group but individual costs. The results showed that most groups achieved their objectives and cooperated, e...
A study emulated a clinical trial using real-world UK healthcare data to explore treatment effects in patients with atrial fibrillation. The method found similar outcomes between apixaban and warfarin, but with differences linked to ethnicity and medication use.
An interdisciplinary team of researchers found that tight junction proteins form a liquid-like material on the cell surface, gradually growing into a belt around the cells. This process, called membrane prewetting by condensates, promotes tight-junction belt formation and makes tissues airtight.
Research highlights key factors for governance of green school playgrounds, including genuine collaboration, inclusive participation, involving committed architects and landscape designers. Studies show that such environments facilitate outdoor learning, creative play, and improve children's concentration and stress management.
A new study found significant intake inadequacies for nearly all evaluated micronutrients, with iodine and vitamin E deficiencies being the most prevalent. The researchers estimated inadequate intakes were higher for women than men in some countries, highlighting a need for targeted dietary interventions.
Scientists have discovered that immune cells migrate to the nasal conchae after vaccination or infection, secreting antibodies locally into the nasal cavity. This finding could lead to more effective nasal vaccinations and new treatments for autoimmune diseases.
A new chemical process can vaporize plastics, reducing waste and creating hydrocarbon building blocks for new plastics. The catalytic process efficiently degrades a mix of post-consumer plastic waste, bringing closer a circular economy for many throwaway plastics.
Scientists have successfully upgraded their atomic force microscope to retrieve imaging data with the time and spatial resolution needed to obtain 3D structure images that provide direct evidence of a hydration layer forming during the dissolution of calcite. The new upgrade enabled researchers to capture high-quality 3D-SFM images in ...
A machine-learning tool can effectively and efficiently subtype pathology samples from patients with RA. This may help scientists find ways to improve care for the complex condition by distinguishing between three subtypes of RA. The tool has also yielded new insights into treatment effects in mice, such as reduced cartilage degradation.
Two studies reveal key proteins involved in micronuclear collapse, including p62 and CHMP7, which can serve as prognostic markers and therapeutic targets for high-CIN tumors. Oxidative damage from ROS triggers the process, causing chromosomal instability and DNA damage that fuels cancer progression.
A growing global understanding of drought's impacts, but significant gaps remain in affected communities and developing countries. Long-lasting droughts heighten awareness, while economic factors influence responsiveness to the issue.
Researchers developed a new tool to track immune health patterns over time, revealing how checkpoint inhibitor therapies work together to recruit new T cells. The study found that the combination therapy produces waves of new T cells with each dose, rather than continually strengthening existing ones.
A study analyzed news reports on scientific evidence, sources of authority, and limitations for three unproven therapeutics. It found that experts' opinions were often cited over scientific publications, and non-experts made claims about safety and efficacy.
Researchers have shown that repeated administration of lipid nanoparticle-encapsulated mRNA therapy significantly extended survival and reduced serum leucine levels in a mouse model of maple syrup urine disease. The treatment approach may represent a potential long-term universal treatment for MSUD.
Research at the University of Tsukuba found high vertebral instability and diffuse low-signal changes in T2-weighted MRI observations to be risk factors for deteriorated ambulation status following different conservative treatments. These findings could help predict whether a patient's ability to walk will be affected by these treatments.
The study found significant geographic variations in concussion diagnoses in US emergency departments, with a higher frequency of diagnoses in the South due to high population density. The researchers highlight the need for tailored public health strategies to address these variations effectively.
A new model developed by scientists can predict intense, localized heavy rainfall events caused by rapid air rises in clouds. This breakthrough offers potential to improve public safety and preparedness through early warning systems.
A new study found that climate change is shifting the regions suitable for growing crops, putting pressure on timber production. As the land needed for producing vital resources becomes scarce, researchers warn of a looming issue that could lead to increased competition and conflict between agriculture and forestry.
Scientists at NIST have created tiny lasers that generate light at yellow and green wavelengths, filling a long-standing gap in the visible-light spectrum. The new technology has potential applications in underwater communications, medical treatments, and quantum computing.
Researchers led by Prof. Michael Brand successfully regenerated photoreceptors in zebrafish, demonstrating they regain their normal function and allowing the fish to recover complete vision. This breakthrough could potentially revolutionize treatment of diseases like retinitis pigmentosa or macular degeneration.
Tregs modulate inflammation to facilitate repair and promote bone formation, enabling improved healing outcomes. The study highlights the potential of targeting immune responses to enhance tissue repair and recovery in fractures.
Entomology professor Esther Ngumbi is studying how flooded conditions affect tomato plants, including changes in microbial community, volatile organic compounds, and gene expression. She warns that increased flooding can undermine climate-resilient crop research.
Scientists at Aalto University and Institute of Physics CAS built an artificial quantum material with topological quantum magnetism, featuring a new state of matter. The researchers demonstrated the highest-order topological quantum magnet, which could provide substantial protection against decoherence in quantum technology.
Researchers at Universiteit van Amsterdam created a PFAS-free synthesis route for pharmaceutical and agrochemical compounds using a trifluoromethyl group attached to sulfur, nitrogen, or oxygen atoms. The method avoids the use of PFAS reagents, offering an environmentally friendly alternative.
The study used spatial transcriptomics and machine learning to analyze gene expression and cell distribution in PanINs, identifying key features of pancreatic cancer progression. Key findings include increased cell proliferation and decreased inflammatory signaling in high-grade PanIN lesions.
Researchers used genetic method Mendelian randomization to show high levels of fasting insulin cause reduction in Lp(a), rather than the other way around. Low Lp(a) is unlikely to be a risk factor for type 2 diabetes, independent of pre-existing hyperinsulinaemia and insulin resistance.
Postmenopausal women who received hormone therapy were biologically younger than those who did not, with a stronger association observed in low-income individuals. The study suggests that promoting hormone therapy could be essential for healthy aging and reducing mortality rates.
A study published in Nature Medicine found that countries with greater inequalities have older brain ages due to environmental factors like pollution and socioeconomic disparities. Participants from diverse geographical populations showed varying levels of brain age gaps, particularly those with dementia.
Scientists have created a new chemical probe to visualize the distribution of sphingomyelin and its degradation by sphingomyelinase during infections. The researchers observed increased metabolization of sphingomyelin molecules during Chlamydia infection, paving the way for targeted strategies against infectious diseases.
A recent study found that human-made secondary organic aerosols (SOAs) contribute up to 53% of total SOA levels today, a significant increase from preindustrial times. This dramatic change is crucial to understanding the environmental impact of human activities on air quality and climate change.
Researchers at Queen Mary University of London have identified a neurohormone responsible for triggering arm detachment in starfish. The team's discovery sheds light on the complex interplay of neurohormones and tissues involved in autotomy, a well-known survival strategy in the animal kingdom.
A study published in Science Signaling explains the mechanism behind persistent pain related to obstructive sleep apnea. The researchers created a chronic intermittent hypoxia environment in mice and observed an increase in cytokines, which cause sensitivity in nociceptors producing prolonged pain sensitivity.
Researchers developed a cylindrical model called REMM to replicate both inner diameters and chemical properties of ribosome tunnels. The model outperformed a conventional carbon nanotube model in accurately reproducing experimentally observed protein structures.
Researchers discovered a non-virulent bacterium, Mycobacterium spongiae, that shares 80% of its genetic material with M. tuberculosis, shedding light on the disease's origins. The study provides valuable insights into the evolution and virulence of TB.
Researchers have developed a smart leaky-wave antenna system based on spoof surface plasmon polaritons that offers flexible control, wide frequency band and high gain. The system can automatically switch between radiation and non-radiation states and track moving targets in real-time.
Monthly gamblers in Massachusetts report increased gambling intensity and harms, as well as negative attitudes towards gambling. The proportion of those experiencing problem gambling jumps to 25.6% from 12.7% in 2014.
A researcher at UC Berkeley has discovered that fungi can transform indigestible plant material into digestible, nutritious food in about 36 hours. The Neurospora fungus is being used to create tasty morsels from food waste, including grain covered with orange Neurospora and moldy bread.
Researchers successfully observe and identify the reactive electron species for photocatalytic hydrogen evolution on metal-loaded oxides, shifting the paradigm on the traditionally believed role of metal cocatalysts. The electrons shallowly trapped in the in-gap states contribute to enhancing the hydrogen evolution rate.
The NEC Society has marked its 10th anniversary by highlighting key achievements in understanding and combating the disease. Over the past decade, the organization has built an empowered community dedicated to transforming pain into power and isolation into collaboration.
Researchers developed a wearable smart mask that captures and analyzes exhaled breath condensate for continuous monitoring of respiratory health conditions. The device offers high accuracy and real-time data transmission via Bluetooth, providing a promising solution for future clinical studies.
The globular springtail's jumping prowess is a unique and spectacular display of agility and speed. By using its furca appendage to launch itself into the air, it can achieve incredible backflips, reaching speeds of up to 368 rotations per second and distances of over 60 times its own height.
The Human AugmentatioN via Dexterity (HAND) center aims to develop robots capable of enhancing human labor through engineered systems of dexterous robotic hands, AI-powered fine motor skills, and human interface. The center's goal is to make robotic assistance accessible and applicable to a wide range of physical actions.