Purdue researchers have successfully isolated and detected drug-metabolizing enzymes from extracellular vesicles, which could enable personalized medicine by monitoring individual responses to prescription drugs. The method may also aid in detecting signs of Parkinson's disease and analyzing liver metabolism.
A team of international astronomers has captured stunning images of over 80 young stars and planetary discs using the ESO's VLT. The research provides a wealth of data on planet formation, revealing diverse populations of planets and planetary nurseries across three star-forming regions in the Milky Way galaxy.
Experts warn space tourists lack crucial information on cosmic radiation exposure risks, which could lead to DNA damage and cancer. The University of Surrey recommends regulations, international standards, and clearer information for safe space travel.
The latest American Psychiatric Association journals feature new treatments across the lifespan for anxiety, depression, and substance use disorder. The March issue of The American Journal of Psychiatry highlights several studies with these findings.
Researchers studied Prorocentrum cordatum to understand its molecular processes, revealing a unique photosynthetic machinery that may help it adapt to changing light conditions. The findings could lead to improved understanding of harmful algal blooms and their role in climate change.
Columbia University engineers have developed a novel approach to create highly conductive single-molecule devices using direct metal-metal contacts and light control. The discovery opens up new possibilities for designing smarter electronic components.
The lack of standardized controls in lifespan studies leads to misleading outcomes and makes it difficult to compare results. Researchers propose solutions for quality control by checking inter- and intra-study consistency of lifespan data.
A study published in Public Health Nutrition found that unhealthy food retailers and advertisements dominate urban school neighborhoods in Greater Tunis, contributing to high rates of childhood obesity. The researchers analyzed over 3600 retailers and nearly 2100 advertisements, revealing that two-thirds were classified as unhealthy, w...
Scientists trained AI models on brain activity data from mice to detect hippocampal ripples, a biomarker of memory, epilepsy, and Alzheimer's disease. The model toolbox can be applied to non-human primate and human data with similar recording techniques.
A multiyear cross-sectional study found a strong association between high daily screen time and lower psychological well-being among preschool-aged children. The study also showed that screen time remained elevated in children from poverty-stricken areas even after returning to pre-pandemic levels in 2021.
Researchers used mass spectrometry imaging and single-cell metabolomics with deep learning to create 3D molecular maps of the brain, enabling a better understanding of chemical interactions within brain tissue. This breakthrough could help address currently intractable neurological diseases.
Researchers developed a mathematical model to optimize World-class 400m and 1500m running performances by considering variability of motor control, oxygen consumption, and energy expenditure. The study found that improving aerobic metabolism and maintaining optimal velocity are crucial for achieving top performance.
Researchers found that firms with mismatched positioning strategies, functional capabilities, and governance modes experience reduced innovation outcomes. Strong marketing capabilities are associated with increased innovation performance in joint development agreements for high differentiation-oriented firms.
Researchers at the University of Córdoba discovered a mutually beneficial relationship between an algae and three bacteria that produces hydrogen and biomass while cleaning wastewater. The combination, composed of Chlamydomonas reinhardtii alga and Microbacterium forte sp. nov., Bacilluscereus, and Stenotrophomonas goyi sp. nov., yield...
Climate models suggest Arctic sea ice will slow down during summer seasons, potentially reducing hazardous conditions for marine transportation, but still posing concerns for ecosystems and global climate change. A York University study found that while the slowdown is plausible, questions remain about its timing.
Researchers used a cruise ship to conduct marine science in Antarctica, highlighting an eco-friendly alternative to traditional research methods. The collaboration increased efficiency and reduced costs, allowing for more comprehensive studies of the Antarctic Ocean.
Researchers successfully enhanced plasma stability in a fusion reaction by utilizing weaknesses in magnetic fields to confine the reaction. This approach, validated through experiments at KSTAR tokamak, improves simultaneous control of instabilities in the core and edge of the plasma.
Researchers successfully synthesized a gold silver and gold copper metal nanocluster with exceptional physical and chemical properties. The team's work provides experimental evidence for understanding and designing nanoclusters at the atomic level, showcasing their potential as ideal model catalysts.
Researchers at Oregon State University have identified a metal-organic framework that can completely remove and break down glyphosate, a widely used herbicide. The material, Sc-TBAPy, shows faster adsorption and photodegradation of glyphosate compared to other MOFs.
A new study reveals that coaches who display 'authentic leadership' qualities, such as empathy and understanding, can strengthen athletes' mental health. This is particularly important for high-level athletes competing at national, international, or university leagues.
The Juno spacecraft has directly measured charged oxygen and hydrogen molecules from Europa's atmosphere, providing key constraints on the potential oxygenation of its subsurface ocean. The findings suggest that oxygen is continuously produced in the surface ice shell, with an estimated 12 kg per second, which could support habitability.
A new tool using electrocatalysis enables precise modification of site-specifically incorporated 5-hydroxytryptophan residues on many different proteins, including full-length therapeutic antibodies. The eCLIC method has potential applications in developing novel biotherapeutics and protein-based research tools.
A new study by Monash University reveals that short-term exposure to high levels of air pollution results in over 1 million premature deaths worldwide every year. The highest mortality burden is found in crowded, highly polluted areas in eastern Asia, southern Asia, and western Africa.
A study by Rebecca Walker found that places with historic racial covenants had lower temperatures, more tree canopy, and less impervious surfaces, indicating reduced exposure to extreme heat. This is particularly pronounced in middle- and lower-income neighborhoods where the covenants have a significant impact.
A novel antibody constant region variant (REW) extends plasma half-life and improves biodistribution, allowing for both invasive and non-invasive delivery. The REW technology also enhances the complement system, providing enhanced ability to kill cancer cells and bacteria.
A pooled data analysis of 752,050 adults found that even modest amounts of leisure-time physical activity can lower stroke risk by 18-29%. The effects are independent of age and sex, suggesting that everyone should be encouraged to engage in some form of physical activity.
A study reveals that restoration strategies in the semi-arid region of Brazil have led to a return of native ecosystem services by improving soil microbial properties. The techniques, including removal of cattle and cultivation of cover crops, have resulted in higher biodiversity and crop yields.
Paleontologists have discovered a new species of marine lizard with dagger-like teeth that lived near the end of the age of dinosaurs. This finding highlights a dramatically different ocean ecosystem to what we see today, with numerous giant top predators eating large prey.
A new approach to menopause is needed, focusing on empowering women with high-quality information and empathic clinical care. The experience of menopause varies for each person, and an individualised approach can help women navigate this life stage.
A UMass Amherst study found that only three types of fruit snacks meet federal dietary guidelines for high-nutrition: dried fruit, fruit puree, and canned fruit with juice. Dried fruit has the highest nutrient density and fiber content, while gummies have the lowest.
A study found that increasing daily step count can counteract the health consequences of too much sedentary time. The optimal number of steps per day to achieve this benefit was between 9,000 to 10,000 steps/day, which lowered mortality risk by 39% and incident CVD risk by 21%.
Researchers have designed a candidate drug to target the K-Ras G12D mutation, responsible for nearly half of all pancreatic cancer cases. The molecule permanently modifies the mutation, stopping tumor growth in cancer cell lines and animal models.
The World Innovation Summit for Health (WISH) has announced its 2024 Global Healthcare Innovation Competition at Web Summit, open to visionary entrepreneurs and health-focused startups. Winners will receive an invitation to showcase their innovations at WISH 2024, investment awards, and access to industry experts.
A new study found that deforestation combined with climate change could negatively impact 84% of North America's lizards by the end of the century. This would lead to a 34% decrease in lizard activity time, making them more vulnerable to overheating.
Scientists from the University of Rochester have developed a novel approach to clean up pollution from PFAS, known as 'forever chemicals', found in various products. The new electrocatalytic method uses laser-made nanomaterials made from nonprecious metals, nearly 100 times cheaper than existing methods.
A novel device developed by University of Auckland researchers has successfully measured faulty gut electrical signals in a human clinical trial. The endoscopic sensor device aims to provide clinicians with a clearer picture of exactly where the electrical signals are misfiring, improving diagnosis and treatment for stomach complaints.
A team of researchers from Japan Advanced Institute of Science and Technology has developed an innovative Bayesian optimization scheme to optimize the performance of silicon heterojunction solar cells. The approach, known as constrained BO, combines three prediction models to determine optimal deposition conditions for catalytic chemic...
A team of astronomers has shed new light on the process of planet formation through a groundbreaking survey of over 80 young stars. The research provides a wealth of data and unique insights into how planets arise in different regions of our galaxy, revealing diverse patterns of planet-forming discs.
A German-American research team created an 'atlas of internet surveillance' by mapping the global ownership of internet service providers. The study shows that authoritarian states control more influential internet service providers than democracies, and often use state-owned transit networks to surveil and censor content. Additionally...
A research team identified manganese oxide and cobalt oxide as effective catalysts for accelerating ortho-to-para conversion of molecular hydrogen. The study provides guidelines for designing anti-evaporation catalysts, which are crucial for long-distance hydrogen transportation.
A new study led by Cleveland Clinic researchers suggests that sildenafil may help protect brain cells from Alzheimer's disease. The study found that sildenafil can lower levels of neurotoxic tau proteins and improve brain function in patients with Alzheimer's.
A large clinical study conducted in South Africa, Uganda, and Zimbabwe found that the dapivirine vaginal ring and daily oral pre-exposure prophylaxis to be safe for HIV prevention among pregnant women. The study involved 248 pregnancies and showed no increased risk of stillbirth or miscarriage.
Different configurations of zinc anodes can help reduce side reactions, increase safety, and improve the performance of rechargeable zinc metal batteries. The proposed designs include 3D Zn anode, printed Zn anode, imprinted Zn anode, and linear Zn anode, which can enhance energy density, cycle life, and power density.
Researchers found that insecticide paint effectively killed mosquitoes for up to a year in Cabo Verde, with good acceptance from the population. The VESTA formulation met WHO efficiency threshold requirements, making it a promising strategy for preventing vector-borne diseases.
This year's Discover BMB program includes top experts unveiling groundbreaking discoveries and revolutionary approaches in biochemistry and molecular biology. Advances in natural product biochemistry and biotechnology will be showcased, along with a deeper understanding of RNA biology, its role in cancer and neurodegenerative diseases,...
A new study by Boston University researchers found robotic-assisted surgery for gallbladder cancer to be as effective as traditional open and laparoscopic methods, offering added benefits in precision and quicker post-operative recovery. The study's findings suggest robotic surgery may pave the way for wider adoption and improve patien...
A new study suggests the Arctic could see its first ice-free day as early as the 2020s or 2030s, with an entire month without floating ice during September by mid-century. This would significantly impact Arctic animals and coastal communities, highlighting the need for low emissions to avoid prolonged ice-free conditions.
The ECNU Review of Education explores the rise of shadow education globally, its cultural significance, and concerns over commercialization and unequal access. The review provides valuable insights for educators and policymakers on addressing shadow education's driving factors.
New research reveals that radioguided surgery can effectively detect and remove metastatic pelvic lymph nodes in newly diagnosed prostate cancer patients. The procedure targets the prostate-specific membrane antigen, improving nodal staging to guide treatment recommendations.
Researchers at TU Graz have discovered that the cause of curling paper lies in solvents contained in the ink, which migrate towards the unprinted side over time. This causes the cellulose fibres on the unprinted side to swell and the paper starts to curl.
Researchers propose a new 'legibility' framework to understand cryptocurrency governance, revealing stages of illegibility, contested legibility, and collaborative legibility. The study examines the US, EU, and Japan's markets, showing they progressed through these states at different rates.
A new study led by researchers at New York University finds that microscopic worms living in the Chornobyl Exclusion Zone have not developed DNA damage from chronic radiation. The discovery suggests that these worms are exceptionally resilient and could provide clues for understanding human risk factors, but it does not mean the region...
Text-to-image AI tools enhance human artists' output, but may hinder novel visual styles. Artists who adopt AI show increased productivity and favorable feedback, while those relying solely on AI struggle with creative stagnation.
A new study by the Microbicide Trials Network found no safety concerns with using the dapivirine vaginal ring during all stages of pregnancy. The research provides sufficient evidence that the ring is safe to use throughout pregnancy to protect against HIV, which poses a higher risk than at any other time.
A new study by researchers at Yale University examines how retirement affects mental health among female workers in China. The research found that rates of hospital admissions for mental illnesses increased following retirement at age 50 for blue-collar women, but not for white-collar females retiring five years later.
A new study suggests that East Asian hominins possessed advanced knapping abilities equivalent to Mode 2 technological features as early as 1.1 million years ago. The research team discovered organized flaking techniques and standardized operational processes, indicating complex mental templates among the toolmakers.
A team of researchers introduces an innovative MILP model with VNS algorithm to optimize UAV inspection routes and schedules for engineering projects. The approach leverages the agility and precision of UAVs to conduct inspections in a fraction of the time and with significantly reduced risk to human inspectors.
A new study found that waist circumference-to-height ratio detects excess fat mass and distinguishes it from muscle mass in children and adolescents significantly better than body mass index (BMI). The measure is inexpensive and accurate, making it a promising alternative to BMI for diagnosing childhood obesity.
Climate change is exacerbating dangerous humid heat conditions in US carceral facilities, with 44 states lacking universal air conditioning. Incarcerated people are disproportionately susceptible to heat-related illnesses, with preexisting health conditions increasing risk.
Researchers at San Diego Zoo Wildlife Alliance have made a groundbreaking discovery that establishes individual baseline values for African elephant blood cell counts, enabling earlier detection and intervention of clinical EEHV infection. This study provides a tool for elephant care facilities to improve preventive medicine and lifesa...