Researchers discovered that lung cancer cells can persist in the presence of cigarette smoke due to a protein pump called ABCG2, which clears damaging molecules from the cells. This mechanism could also contribute to resistance to pharmaceutical treatments in cancer cells.
Researchers have developed a nanosurgical tool that enables them to study individual living cancer cells in real-time, allowing for vital understanding of how they react to treatment and change over time. This breakthrough could lead to more effective cancer medication, particularly for glioblastoma, the deadliest form of brain tumour.
Researchers at Johns Hopkins Kimmel Cancer Center and University School of Medicine developed an algorithm, REAL-FAST, to identify high-risk precancerous lesions on the fallopian tubes. The test accurately detected cancer 95.8% of the time and correctly ruled out cancer 97.1% of the time.
A new study from Karolinska Institutet has found a clear link between childhood adversity and the risk of mental illness later in life. The research suggests that genetics and environment play a significant role in contributing to adult psychiatric disorders, highlighting the need for targeted health care interventions within families ...
A recent study published in the journal Autism has found that five times more nonspeaking autistic teenagers and adults demonstrated knowledge of written language conventions than expected. This research suggests that many autistic individuals are literate and may be able to learn alternative forms of communication through writing.
Astronomers have spotted a galaxy that stopped forming new stars over 13 billion years ago, when the universe was just 700 million years old. The 'dead' galaxy experienced a short and intense period of star formation, followed by rapid quenching.
A University of Ottawa study found that older adults understand emoji meanings but are hesitant to use them due to low confidence and technical expertise. The research suggests promoting emoji use can combat ageism and reduce loneliness.
A study found that people with essential tremor are at a heightened risk of developing dementia, with rates 3 times higher than in the general population. Researchers also found a significant increase in mild cognitive impairment among those with essential tremor.
A genetic mutation in a quarter of all Labradors hard-wires them for obesity, making them hungrier between meals and burning fewer calories. Owners must be strict with feeding and exercising their dogs to keep them slim.
Researchers found that understanding airflow patterns is crucial to reducing pathogen dispersion in classrooms. By analyzing airflow dynamics, they discovered an under-floor air distribution concept combined with a ceiling-distributed exhaust system can significantly reduce airborne pathogens by up to 85%.
Researchers have discovered why some RNA-splicing drugs work better than others, revealing a key factor that impacts treatment efficacy. By analyzing the interactions between drugs and RNA, they found that combining splice-modifying drugs targeting the same gene segment can lead to greater therapeutic effects.
A recent study published in Lancet Infectious Diseases found that vaccinated individuals had a lower risk of severe COVID-19 outcomes compared to unvaccinated individuals. The study also showed significant reductions in hospitalization and death rates from COVID-19, particularly among older individuals and those with compromised immune...
Researchers have discovered two genetic variants associated with generalized pustular psoriasis (GPP), a rare and serious condition characterized by widespread skin lesions and inflammation. These variants, found in the MEFV gene, may hold promise for new diagnostic and therapeutic approaches to GPP.
Researchers at IMBA discovered a parent-of-origin effect in nematodes, suggesting the first step in genomic imprinting's evolution. This finding provides insight into how imprinting arose independently in mammals and plants over 100 million years ago.
Researchers discovered charge fractionalisation in an iron-based metallic ferromagnet using laser ARPES spectroscopy, revealing collective excitations and quasiparticles. The study challenges fundamental quantum mechanics by showing electrons can behave as independent entities with fractionally charged pockets.
Researchers at Princeton University have developed a new AI chip that can run powerful AI systems using significantly less energy than existing semiconductors. The chip is designed to be compact and efficient, enabling its deployment in dynamic environments such as laptops, phones, and data centers.
A recent study by researchers at LMU Munich discovered that neural networks adapt to sensory stimulation on an individual nerve fiber basis, rather than transferring improvements to neighboring fibers. This finding suggests that varied sensory experience throughout life is essential for maintaining cognitive fitness.
A randomized clinical trial found that linkage case management intervention did not improve 12-month mortality outcomes for hospitalized people with HIV. The study involved 500 participants and sheds light on the potential role of this intervention among hospitalized individuals with HIV.
A new study reveals that tropical herbivores moving into subtropical waters are at risk of overgrazing seagrasses, which could lead to the decline of these vital habitats. To mitigate this, researchers emphasize the importance of protecting water quality and providing sufficient light for seagrasses to thrive.
Researchers investigated how household size and adult-to-child ratio affect children's vocabulary scores. They found that higher adult-to-child ratios correlated to higher child vocabulary scores and lower household chaos scores, particularly in Hispanic families.
Researchers develop AI-based system to track small metallic objects in Low Earth Orbit, outperforming classical detection methods. The system's high detection rate and low false alarm rates make it suitable for proactive decision-making and intervention strategies.
A new study analyzed over 5,700 invasive plant species and found nearly one-third exhibited lag periods between introduction and rapid expansion, with the average time being 40 years. This latency allows them to be overlooked, contributing to their eventual emergence as a serious ecological threat.
Dr. Tiffany Carson is part of the SAMBAI team, which will develop novel approaches to addressing cancer inequities in prostate, breast, and pancreatic cancers spanning diverse cohorts. The team aims to build a comprehensive measurement of social, environmental, genetic, and biological factors to define the causes of disparate outcomes.
Research has shown that dulaglutide, a diabetes drug, can reduce depressive-like behaviors in mice. The study identified four major pathways involved and linked markers of depression to lipid metabolism and tryptophan metabolism. This new perspective may facilitate the use of dulaglutide as a potential therapeutic strategy for depression.
Scientists have developed a nanoporous magnesium borohydride structure that stores five hydrogen molecules in three-dimensional arrangement, achieving unprecedented high-density hydrogen storage. The material exhibits a capacity of 144 g/L per volume of pores, surpassing traditional methods and offering a promising alternative to large...
A team of NYGC researchers, led by Dr. Melissa Davis, has received a $25M grant to study cancer inequities in diverse populations. They aim to analyze genomic data from participants with African ancestry to identify factors contributing to disparities in cancer outcomes.
A new study finds that communities of color in the US suffer from nearly 8 times higher rates of pediatric asthma and 1.3 times higher risk of dying prematurely from exposure to pollutants. The study highlights the need for place-based policies to address health disparities linked to air pollution.
A study published in the International Journal of Gynecology & Obstetrics found that Medicaid expansion in Maryland led to improved newborn outcomes, including better Agar scores and reduced need for assisted ventilation. However, there were no significant differences in Cesarean section deliveries.
A recent study at Salk Institute evaluates the reliability of patient-derived organoids as a clinical model for pancreatic cancer. The findings reveal that organoids' gene expression and drug responses are not affected by commercial extracellular matrix brands, but one product increases growth rate.
A recent study published in Neurology found that white people with sleep apnea are at increased risk for stroke, while Black people with the condition have a reduced risk when using CPAP machines. The study suggests that racial differences in sleep apnea severity and treatment may impact stroke risk.
Researchers developed a machine learning model to assess the quality of health news stories, outperforming laypeople in evaluating their accuracy. The model used expert criteria to classify articles as 'satisfactory' or 'not satisfactory', highlighting the need for multiple criteria in evaluating news.
A new study found that NC prosecutors believe DIH laws reduce overdoses and illicit drug distribution, but this is contradicted by evidence. The number of DIH prosecutions does not correlate with community-level variables like overdose rates.
Researchers from OIST used X-ray micro-CT to study a 38 million-year-old termite pair trapped in amber, revealing a male and female in tandem running behavior. The discovery provides new insights into the fidelity of behavior fossilization in amber.
The study reveals that rod shapes are crucial for effective swimming, enabling microbes to navigate their environments efficiently. Advanced microscopy visualized the behavior of proteins inside the cell, confirming the importance of specific proteins in shifting cell shape.
Researchers have discovered unique electromagnetic signals in the debris of a neutron star merger, which could provide new constraints on axion-like particles and their potential role in dark matter. The findings were made using data from NASA's Fermi-LAT gamma-ray telescope.
A study funded by the National Institutes of Health found that more than 70% of American Indian young adults aged 20-39 and 50% of teens have abnormal or high cholesterol. High LDL cholesterol was linked to plaque buildup and cardiovascular events, emphasizing the need for early screenings and culturally relevant education.
A computational model of the more than 26 million atoms in a DNA-packed viral capsid has expanded our understanding of virus structure and DNA dynamics. The study found that the DNA formed switchback loops as it was pushed into the capsid, similar to how DNA is organized in eukaryotic cells.
Researchers at the University of Konstanz have developed a theoretical model for stable qubit information exchange by utilizing photons as a means of transport. The new method uses stimulated Raman emissions to control the photon, enabling precise temporal shape optimization and addressing environmental perturbations.
The team's innovative design enables ultra-compact quasi-true-time-delay technology, increasing data rate and channel capacity by nearly doubling that of conventional wireless arrays. This breakthrough could lead to faster service and more data transmission for cellphone users.
A new computational model uses neural network architecture to generate accurate predictions of airflow while reducing computational cost. It can capture most of the original physics in a flow prediction with relatively little processing complexity.
A new research proposes a novel unified variational model that simultaneously obtains haze-free image, transmission map, and noise map. The model achieves both haze removal and noise suppression, outperforming previous methods.
Rice University researchers have developed a transformative approach to harnessing the catalytic power of aluminum nanoparticles by annealing them in various gas atmospheres at high temperatures. This allows for modifying the structure of the oxide layer, making the nanoparticles versatile tools for different applications.
A new review paper from Brigham and Women's Hospital concludes that menopause does not uniformly elevate the risk of depression and other mental health conditions. Certain groups, such as those with a history of depression or severe sleep disturbances, are more likely to experience depressive symptoms during menopause.
Wild stingless bee colonies in the Colombian Andes develop tolerance to the insecticide abamectin, which is derived from cattle medication ivermectin. Despite high concentrations of abamectin being lethal to bees, tolerant colonies grow at similar rates as non-tolerant ones
Researchers developed a scaffold with controlled pore sizes (200-700 microns) and shapes, using FDM printing technique. The results showed a favourable cellular response and mechanical properties, making it promising for bone defect regeneration.
Researchers at Washington State University discovered a way to trick bacteria into sending death signals to stop the growth of their slimy biofilms, which can lead to deadly infections. The study found that these 'death extracellular vesicles' can reduce bacterial growth by up to 99.99% in laboratory experiments.
A new study found that 51% of Canadian newspaper coverage during the 2019 federal election was classified as infotainment, featuring personal foibles and horse races alongside substantive coverage. Infotainment categories include personalization, sensationalization, and decontextualization, with significant impacts on voter information.
Researchers at UNSW Sydney have developed a new technology offering test strips for rapid, on-the-spot disease detection. The test strips are accurate and cost-effective, making them suitable for various applications including public health, environmental diagnostics, and cancer cell detection.
Scientists have created a way to correct distorted light patterns in real time without needing to reapply the same distortion. This method uses nonlinear optics and exploits difference frequency generation to produce an aberration-free output beam.
A large population-based study found that taking 9000 to 10000 steps daily reduces death and cardiovascular disease risk in highly sedentary individuals. The optimal number of steps per day to counteract high sedentary time is between 4000 and 4500 steps/day, lowering mortality risk by 39% and incident CVD risk by 21%.
Researchers at Sophia University have optimized air–fuel mixing conditions for efficient ammonia combustion in engines, bringing us closer to viable ammonia-fueled vehicles. Swirling flow patterns promote better air and fuel mixing, leading to improved combustion and reduced emissions.
Nai-Hui Chia, an assistant professor of computer science at Rice University, has received a National Science Foundation CAREER Award to develop a new theoretical framework for efficient quantum algorithms. The grant aims to enhance the security of quantum cryptography and tackle complex problems in physics and machine learning.
A study published in Pediatric Research found that waist circumference-to-height ratio accurately detects fat obesity in children and adolescents, distinguishing it from muscle mass. This method is more effective than BMI in predicting premature death and could replace BMI as an assessment tool for childhood obesity.
A new prediction tool has been developed to identify individuals at high risk for hepatocellular carcinoma (HCC) due to alcohol-related liver disease. The nomogram uses key risk factors, including heavy drinking, age, and diabetes, to predict HCC risk with high accuracy.
A Texas A&M professor will lead a team in evaluating the distribution and potential hazard of volatile organic compounds (VOCs) in East Palestine, Ohio, using a mobile platform. The research aims to inform response methods to measuring air quality following environmental disasters.
The eco-metropolis model redefines urban development by prioritizing ecological conservation alongside innovation and economic growth. It offers a comprehensive framework for policymakers and urban planners to adopt, merging green technologies with urban growth.
A recent study published in Marketing Science found that brands supporting Black Lives Matter (BLM) suffer a decline in consumer social media activity, including fewer followers and likes. In contrast, brands with more historical prosocial posting on social media and socially oriented missions may benefit from BLM support.
New research by Boston University School of Medicine found that while few clinicians have adopted the 2020 ACS cervical cancer screening guidelines, most are open to change if supported by scientific evidence and recommended by professional organizations. The study identified logistical issues and concerns about missed detection as bar...
Biologist Elizabeth Carlen's investigation into iNaturalist data revealed biased species distribution in St. Louis, with northern parts of the city underrepresented. The framework developed by Carlen and her co-authors identifies four filters contributing to this bias: participation, detectability, sampling, and preference.
Scientists create detailed models of the terrestrial water cycle using high-resolution satellite data to predict floods, droughts, and other extreme events. The Digital Twin Earth Hydrology Platform allows for interactive simulations and visualizations to enhance flood and landslide prediction and optimize water resource management.