The Complexity Science Hub is launching a new PhD program in Austria, focusing on complexity research to address current challenges. The interdisciplinary program will provide students with expertise in data, network, and complexity science.
A team of scientists has developed a novel vaccine approach that induces long-lasting protective immunity against SARS-CoV-2 virus in pre-clinical models. The Clec9A-RBD antibody construct targets specific dendritic cells, leading to exceptional durability of immune responses and potential to address shortcoming of current mRNA vaccines.
The study reveals common themes among participants' responses, including the constraints of ableist perspectives, challenges in finding a 'sweet spot' in career planning, and a disconnect between autistic youth's needs and available resources. The authors emphasize the need for individualized support, neurodiverse acceptance, and colla...
Researchers investigate sidewall rockburst of highly stressed D-shape tunnel under impact load. The study reveals that the failure process remains unchanged, but the volume and severity of rockbursts decrease with increasing horizontal prestress.
A study investigated current outcomes after revascularization for angiographically confirmed very late stent thrombosis (VLST), revealing a total MACE rate of 35.46%. Left ventricular ejection fraction and peak troponin I at VLST onset were independent predictors of MACE.
A new study published by the University of Bath found that adolescents are more vulnerable to cannabis use disorder than adults, despite using cannabis less frequently. The study showed that adolescents reported greater negative impacts on daily functioning and symptoms of cannabis use disorder.
A pediatric observation unit with a psychiatric comanagement model significantly lowers pediatric emergency department length of stay and inpatient psychiatric admission rates. This innovative approach also avoids contributing to 30-day readmission rates, presenting potential savings for inpatient psychiatric resources.
Researchers developed a structure called multiplexed neuron sets to reduce crosstalk in optical neural networks. The new backpropagation training algorithm achieved comparable performance while improving energy efficiency by a factor of 10.
Researchers developed a new method for nose-to-brain drug delivery using HS15 micelles to target insoluble drugs. The study found that the micelles provided higher and more sustained brain distribution, with rapid entry into the brain region after intranasal administration.
RMIT researchers have found that the liquid-solid boundary can fluctuate back and forth, with metallic atoms near the surface breaking free from their crystal lattice. The phenomenon occurs at unexpectedly low temperatures and is observed up to 100 atoms in depth.
A national survey of nearly 1,600 US parents found that most lack knowledge about newborn screening and cystic fibrosis, leading to difficulties in understanding abnormal test results. The study emphasizes the need for greater public awareness and support from healthcare teams to improve outcomes for infants with cystic fibrosis.
A nationwide training program aims to equip clinicians with digital tools for targeted fatigue, insomnia, pain, depression, and anxiety in cancer patients. The project will train 600 clinicians in technology-augmented care.
Researchers have determined an optimal 'dose' for red light therapy, which can deliver significant therapeutic improvements, including the regeneration of damaged nerve cells. The treatment involves delivering light directly to the site of injury, resulting in increased cell viability and reduced tissue scarring.
A new case report presents OPM-MCG as a potential method for therapy monitoring in fulminant myocarditis. The study reveals that OPM-MCG can detect substantial myocardial injury and monitor therapy response, aligning with cardiac magnetic resonance findings.
NeoHunter systematically detects various neoantigens generated by molecular alterations in tumors. The software accurately estimates peptide–HLA binding and evaluates immunogenicity of TCR recognition on pMHC complexes, confirming candidate neoantigens. This comprehensive tool is valuable for advancing personalized cancer vaccines.
A recent study at the Hebrew University examines the impact of memorial days on national unity amidst political polarization, revealing a notable decline in affective polarization during Holocaust Memorial Day. The research suggests that sadness plays a pivotal role in temporarily reducing societal divisions and safeguarding cohesion.
A recent study reveals significant racial and ethnic disparities in all-cause and cause-specific mortality among US youth. The findings highlight a disproportionate burden of mortality among American Indian or Alaska Native and Black youth, particularly those involving firearms.
A systematic review of psilocybin for treating symptoms of depression has been placed under expression of concern by The BMJ due to a methodological concern related to an error in the calculation of standardized mean differences. This may have resulted in overestimated benefits of psilocybin treatment.
Researchers from Tokyo Metropolitan University created a new model to study the transmission of forces through amorphous solids like concrete and cement. They found that areas between hard regions 'harden' to produce elongated force chains, leading to softer materials with more uniform stiffness.
The Society for Cardiovascular Angiography and Interventions (SCAI) recognized several award recipients for their exceptional contributions to the field of interventional cardiology, including Dr. Antonio Colombo and Jonathan M. Tobis for the F. Mason Sones Distinguished Service Award, and Frank F. Ing for the Helping Little Hearts Lif...
The Society for Cardiovascular Angiography & Interventions (SCAI) awarded the Master Interventionalists of SCAI (MSCAI) designation to outstanding interventional cardiologists who demonstrate excellence in invasive/interventional cardiology. The designation recognizes clinical care, innovation, publication, and teaching achievements.
Dr. James B. Hermiller, MD, MSCAI, assumes presidency of Society for Cardiovascular Angiography & Interventions (SCAI) for 2024-25. With extensive experience in interventional cardiology and leadership roles, he aims to drive excellence in patient care.
The Society for Cardiovascular Angiography & Interventions (SCAI) presents its '30 in Their 30's' award to thirty early-career interventional cardiologists, recognizing their outstanding leadership and commitment to improving patient care. The recipients are the future of the field and will continue as valuable contributors to SCAI.
The Society for Cardiovascular Angiography & Interventions has selected 12 new early-career interventional cardiologists to participate in the Emerging Leader Mentorship Program. The program aims to enhance their skills and prepare them for leadership positions in medicine.
A new program at SCAI's Scientific Sessions provides medical students with hands-on experience in interventional cardiology. The program aims to increase diversity in the field by introducing students to various cases and devices used in Interventional Cardiology.
SCAI has announced the selection of Mariem A. Sawan as the 2024-25 SCAI-WIN CHIP Fellowship recipient, providing her with $115,000 funding to pursue advanced training in complex and high-risk coronary intervention. This fellowship will enable her to develop skills and knowledge in interventional cardiology.
Scientists at Umeå University have identified how a protein complex called the Mediator regulates gene expression, leading to slower cell division. This discovery may pave the way for new treatments for diseases related to uncontrolled cell growth, such as tumors.
The prevalence of lung cancer mutations varies significantly across different ethnic groups in Latin America, highlighting the need for region-specific medical interventions. Enhancing molecular diagnostic and research efforts is crucial for effective management of cancer in this population.
New discoveries about Jupiter's magnetosphere shed light on its interaction with the solar wind and Earth's magnetic field. The research, published in AGU Advances, shows that Jupiter has a largely closed magnetic field at its poles but open field lines, which could influence Earth's space weather forecasting.
The DurAVR Transcatheter Heart Valve has shown favorable results in improving hemodynamic performance and blood flow characteristics for patients with severe symptomatic aortic stenosis. The device was successfully implanted in 100% of cases, with no moderate or severe paravalvular leaks observed.
Researchers from North Carolina State University and the University of Pittsburgh studied how pure spin currents move through chiral materials. They found that the direction of spin injection affects its absorption in chiral materials, which could enable the design of energy-efficient spintronic devices for data storage, communication,...
A study published by University of Pittsburgh researchers found that ACA insurance expansions led to an increase in patients receiving care at accredited cancer hospitals in Pennsylvania. The study suggests that these expansions make a difference in improving access to high-quality cancer care, particularly for those living in areas wi...
Researchers from the University of Tokyo have developed a novel approach to manage waste heat in microcircuits by adding a tiny coating of silicon dioxide. This increases the rate of heat dissipation, allowing for faster cooling and potentially leading to smaller and cheaper electronic devices.
Severe hip OA linked to worse functional impairment and increased ASD severity even after surgery, according to a study published in The Journal of Bone & Joint Surgery. Patients with severe bilateral hip OA had poorer physical functioning, disability scores, and correction of spinal alignment.
The employment-to-population ratio for people with disabilities increased from 36.5% in March 2024 to 37.9% in April 2024, up 3.8%. The labor force participation rate also rose, from 40.3% to 40.6%, as individuals with disabilities remain engaged in the workforce at a similar rate to last month.
Researchers found that white dwarfs continuously consume smaller objects in their path, explaining the presence of heavy metals on their surface. The 'natal kick' during formation alters the dynamics of surrounding material, causing comets and asteroids to become elongated orbits and move as one coherent unit.
Researchers have discovered a promising approach to engineer semiconductors by tweaking isotopes, which can influence optical and electronic properties. The study demonstrates that small changes in isotope masses can shift the optical bandgap, enabling tunability for designing new devices.
The PSMAfore study found that 177Lu-PSMA-617 prolonged radiographic progression-free survival and improved PSA response rate compared to a change in ARPI. Treatment with 177Lu-PSMA-617 also increased objective response rate, regardless of prior treatment.
A study by Raheel Ahmed Shaikh and colleagues models the most cost-efficient path to Australia's fully renewable electricity grid. The optimal route would require significant expansion of generation and storage, but could reduce costs with interconnection between eastern and western grids.
A global study finds that new airport construction benefits less-developed cities with increased accessibility to the global aviation network, promoting inclusive growth and connectivity. The research used nighttime light intensity as a proxy for economic development, analyzing over 13,000 cities worldwide.
Researchers discovered that plants employ ABA to close stomata, obstructing spider mites' entry points and significantly reducing pest damage. The closure of stomata also coincides with the production of ABA, a hormone linked with drought response.
Researchers at DKFZ and UMM found that NK cells can impair the effect of cancer therapies using immune checkpoint inhibitors by controlling activated T cells. They identified B7H6 as a recognition molecule for NK cell attacks, which could limit excessive activation and expansion of T cells.
New clinical results show endovascular therapy as an effective and safe alternative to bypass surgery for both women and men with PAD. However, women remain underrepresented in PAD trials and are less likely to undergo endovascular revascularization.
A new study found extensive alternative splicing of messenger RNA in untreated multiple sclerosis patients compared to healthy controls. Interferon-ß therapy corrected dysregulated alternative splicing, linking it to future clinical exacerbations.
Scientists at Umeå University developed a natural product-like molecule Tantalosin that inhibits interaction between proteins reshaping membranes inside cells. The study reveals a new noncanonical autophagy pathway and potential benefits for cancer treatment.
FQxI appoints Pinar Emirdag to its Board of Directors, leveraging her financial technology expertise to support paradigm-shifting research and promote equity in science. Emirdag brings over two decades of experience working with global regulators and academics.
A new study estimates that gas stove use in U.S. households may be responsible for up to 200,000 childhood asthma cases annually, with high levels of nitrogen dioxide exposure also causing thousands of deaths. The research found that even electric stoves produce no NO2, and that ventilation is key to reducing pollutant exposures.
Researchers found that Mental Health First Aid training improved correctional officers' ability to distinguish between mental health challenges and other issues. The training also positively impacted their attitudes toward referring incarcerated individuals to mental health professionals. However, there is a need to enhance the mental ...
Research warns that law fails victims of financial abuse, with no effective mechanisms to compel lenders to transfer debt. The study recommends greater responsibility for coerced debt and restoration of credit records following the end of an abusive relationship.
Researchers propose forming a network of sister cities to track and raise awareness about the spread of climate-related impacts and responses to urban disasters globally. This network aims to foster ideas and best practices for coping with consequences of climate change, including extreme weather events.
Researchers Michael Platt and Peter Sterling link declining fertility to despair, social fragmentation, and economic uncertainty, posing existential threats to humanity. The study highlights the need for interventions addressing hopelessness and promoting social connections to prevent population collapse.
Judit Szabo has been appointed as the new editor-in-chief of Ornithological Applications, with expertise in conservation biology and ornithology. She will work closely with current editor-in-chief Catherine Lindell until June 2024 and take over full responsibility on July 1, 2024.
Real-PE analysis reveals women and Black patients were less frequently treated with minimally invasive therapy compared to men or non-Black patients. The study found higher bleeding rates among women and white people compared to Black people.
Rising global temperatures are driving up nest temperatures, compromising bumblebees' ability to construct livable nests. Bumblebee colonies may struggle to adapt to these conditions, leading to a decline in population and range.
Researchers developed an in-situ cancer vaccine that targets mutated proteins on cancer cells and triggers immunity. The vaccine was combined with chemotherapy, increasing survival rates in AML patients.
Researchers have discovered that medieval English red squirrels hosted the leprosy bacterium M. leprae, shedding light on potential transmission pathways between animals and humans during the Middle Ages. This finding highlights the importance of understanding animal hosts in predicting disease persistence.
A new study reveals that current national targets for removing CO2 from the atmosphere will not be enough to achieve the 1.5 ºC warming limit set by the Paris Agreement. The research finds that carbon dioxide removal methods have a small but vital role to play in achieving net zero and limiting climate change impacts.
New research reveals that ice shelves don't just buckle, but fracture when weighed down by meltwater lakes. This fracturing could cause vulnerable ice shelves to collapse and contribute to sea level rise.
Researchers at the University of Chicago show that a drug molecule targeting RNA modifications associated with neuroblastoma suppresses tumor growth in mice. High levels of METTL3 expression were linked to significantly lower survival rates in patients, suggesting it drives tumor growth.
Researchers at Northwestern University used statistical physics to corroborate Austrian psychologist Fritz Heider's 1940s social balance theory, which states that enemies of an enemy are friends. The study successfully integrated both constraints of the theory, confirming it for the first time in real-life social networks.