Researchers found a new solid-state reaction process between different multicomponent phases during ablation, leading to improved thermodynamic stability and enhanced ablation performance. The composition evolution allowed the underlying phases to remain stable under higher oxygen partial pressures.
Researchers at the University of Manchester have developed an ultra-pure form of silicon that can be used to construct high-performance qubit devices, a crucial component for scalable quantum computers. The breakthrough could enable the creation of one million qubits, which may be fabricated into pinhead-sized devices.
The study of three Roman-era lead ingots from Los Escoriales de Doña Rama reveals the importance of lead production and exportation in ancient Cordoba, a major center for smelting lead during the Roman period. The ingots, dated to the first century A.D., demonstrate the region's significant role in Mediterranean trade.
Macquarie University researchers debunked a 75-year-old theory about sound localization, revealing that humans use a simpler neural network. This finding could unlock next-generation hearing devices and improve smart devices' ability to understand speech in noisy environments.
Researchers created an ultra-small vision implant with single-neuron sized electrodes, allowing for thousands of 'pixels' to be stimulated simultaneously. The implant's unique combination of flexible materials ensures long-term functionality and stability.
A new study found that children who spent more time being sedentary in childhood had a higher risk of developing heart enlargement, which increases the risk of heart attacks and premature death. In contrast, light physical activity was shown to reduce this risk by 49%.
A study published in JAMA Network Open found that combining cannabis and nicotine use during pregnancy significantly increases the risk of poor health outcomes for newborns. Infants born to mothers using both substances are at a fourfold higher risk of infant death compared to those using neither substance. Abstaining from at least one...
Researchers discovered that aggressive cancer cells pull more strongly on the extracellular matrix than on themselves, while noninvasive cells pull more strongly on themselves. The study found that the interplay between these contractility modes determines a cell's potential for escape and tumor aggressiveness.
Researchers developed a method to quantify mRNA transcription and degradation rates within individual cell types, uncovering varied regulatory rates across genes. The study provides novel insights into how pluripotent cells adopt specialized identities through gene expression.
Researchers developed a predictive model, TRTpred, to identify the most potent cancer killing immune cells using artificial intelligence. The model achieved 90% accuracy in identifying tumor-reactive T cells and can be applied to personalized cancer treatments.
The research group found that the Japanese population can be divided into three clusters, with different concentrations in Okinawa, Northeastern Japan, and Western Japan. They also identified genetic variants associated with hereditary breast cancer and provided insights into gene sequences derived from Neanderthals and Denisovans.
A new study suggests that parents' monitoring of their teenagers can reduce substance use by making them think twice about it. The research found that kids are less likely to try alcohol or drugs if they believe their parents know their whereabouts.
A study by Ohio State University found that rural Americans are less likely to initiate care for substance use disorders and have limited access to ongoing treatment compared to urban residents. The Collaborative Care Model may be a potential approach to addressing these challenges.
Researchers developed a cost-effective nanoparticle catalyst that converts CO2 into CO, producing syngas for valuable compounds. The β-Mo2C/SiO2 catalyst demonstrated high activity and stability compared to traditional precious metal-based catalysts.
Researchers created GraSSRep and rhea, tools that outperform current methods for handling repeats and structural variants in metagenomic data. These methods use self-supervised learning and graph neural networks to analyze microbiome data, offering new insights into biological processes and potential applications in antibiotic resistance.
Researchers developed a new 'proactive vaccinology' approach to build vaccines before disease-causing pathogens emerge. The Quartet Nanocage vaccine trains the immune system to target specific regions of eight coronaviruses, providing broad protection against known and unknown strains.
A region in alpha-synuclein protein aggregates has been identified as a potential therapeutic target to prevent conversion into toxic amyloid fibrils, which accumulate in the brains of people suffering from Parkinson's disease. The discovery opens the door to developing new therapeutic strategies for inactivating these toxic forms.
Researchers at Pitt and Drexel have discovered that electrocatalysts can promote chemical reactions that generate ozone in water through corrosion and solution phase reactions. This breakthrough could lead to the development of more efficient and sustainable electrochemical ozone production technologies.
Researchers explore how art-based approaches can help envision possible futures in higher arts education contexts. The study categorizes art forms into visual, technology-dependent, and interactive categories, highlighting their potential for nonverbal expression and immersive experiences.
Researchers found that the loss of large herbivores like tapirs and deer reduces leaf damage caused by pathogens, leading to increased plant species richness. In contrast, insect damage remains unaffected, suggesting a more complex relationship between plants and their natural enemies.
A recent study found that approximately 30% of India's PM2.5 air quality improvements can be attributed to favorable meteorological conditions, highlighting the need for additional mitigation measures. The researchers also noted that emissions of key PM2.5 precursors have not decreased and may indicate ineffective or under-enforced pol...
A clinical trial shows that cytisinicline can help people quit vaping by reducing the likelihood of relapse and improving behavioral support. The study found that participants taking cytisinicline were more than twice as likely to abstain from vaping for weeks 9-12 compared to those receiving a placebo.
A new study among Finnish ninth-graders identified four perfectionistic profiles associated with varying levels of psychological well-being. The study found that perfectionistic profiles, particularly those characterized by high concerns, are linked to poorer well-being, including burnout and anxiety symptoms.
Researchers developed a nano-IR contrast imaging method using surface phonon polaritons to enhance photoinduced dipole force on ultrathin samples. This technique offers improved sensitivity and contrast for sensitive nanoimaging of specific molecules.
A pioneering CRISPR gene editing trial has demonstrated significant improvement in vision for 79% of participants with inherited retinal degeneration. The study's findings support further research into the potential of CRISPR-based treatments for inherited blindness.
Researchers at Rice University have successfully synthesized a group of natural compounds known as fusicoccanes, exhibiting diverse biological activities. The study leverages modern organic chemistry and engineered enzymes to achieve the synthesis of complex molecules.
Researchers discover a new mechanism of neural plasticity underlying learning and memory processes, highlighting the crucial role of chondroitin sulfates in brain function. The study provides insights into how these molecules contribute to synaptic modifications and spatial memory.
A new study by Boston University School of Public Health found that less than 15% of US college students can administer naloxone, a life-saving medication for opioid overdoses. Despite this, nearly 62% of students can identify signs of an overdose and nearly 67% feel comfortable calling emergency services.
Researchers found a significant increase in time dedicated to LGBTQI+ health content in medical school, but gaps persist in curriculum and faculty training. The median time dedicated to these topics increased from 6 hours in 2011 to 11 hours in 2022.
The Ottawa Hospital is receiving a $59 million grant to boost Canada's capacity for life-saving biotherapeutics, including vaccines, gene therapies, and cell therapies. The funding will support the construction and operation of a world-class biomanufacturing facility at its new campus.
462 medieval manuscripts from Speyer, Worms, and Mainz to be digitized for public access, providing new insights into cultural heritage of seven centuries. High-quality digital reproductions will facilitate exploration of historical textual traditions.
The North American Bsal Task Force has helped keep the novel pathogen at bay by developing diagnostic techniques, a rapid response template, and a surveillance program. Thirty-five of 80 North American amphibians can be infected with Bsal, causing lethal skin disease in susceptible species.
A study evaluating contract treatment in Sweden found that this sanction significantly reduces recidivism and substance-related adverse health events compared to community sanctions or prison sentences. Providing treatment yields better results than punishment, addressing the root causes of criminality often linked to substance misuse.
BANKSY, a new AI software tool, automatically recognises cell types in tissues with high accuracy. It considers both molecular profiles and tissue surroundings, enabling faster and more precise analysis of diverse diseases.
A study published in Science reveals two patterns of tumor-infiltrating B cell responses: germinal center-like and extra-follicular. The former is associated with anti-tumor immunity, while the latter is linked to an immunosuppressive tumor microenvironment. Researchers propose targeting atypical memory B cells for cancer immunotherapy.
Astronomers have observed the faint light from stars in the host galaxies of three ancient quasars, revealing clues to how the earliest supermassive black holes and galaxies evolved. The study suggests that some of the earliest
Researchers developed a computational model simulating fruit fly wing development to identify mechanisms behind organ generation. The model revealed two distinct classes of chemical signaling pathways that produce curved or flat tissues.
Researchers at DGIST have developed three-dimensional retinal electrodes with a convex braille shape, which can stimulate remaining normal nerve cells in the retina. This technology aims to partially restore vision to patients with blindness by minimizing distance to cells and reducing current required for stimulation.
Researchers at University of Colorado Boulder discovered that hydrogen atoms in Venus' atmosphere go into space, causing the planet to lose roughly twice as much water every day. The team found that a molecule called HCO+ is responsible for this process, which may have driven Venus to its dry state.
A study published in JAMA Pediatrics reveals that children diagnosed with hypertension are at a higher risk of major adverse cardiac events later in life. Improved detection, follow-up, and control of pediatric hypertension may reduce the risk of adult cardiovascular disease.
Undergraduate nursing students in Morocco struggle with a disconnect between classroom learning and real-world practice. Insufficient support, lack of supervision, and poorly scheduled internships are among the main issues identified.
A new data center aims to tackle emerging air quality issues in China, providing a comprehensive platform for scientific research and collaboration. The China Air Pollution Data Center (CAPDC) offers high-quality datasets and tools to help combat ozone pollution and other complexities.
Researchers found that tiny displacements of picoscale atoms can significantly impact optical properties, leading to potential applications in imaging and remote sensing. By controlling the degree of atomic disorder, they aim to develop crystals with advanced infrared imaging capabilities.
Researchers developed a novel technique to visualize meningeal lymphatic vessels in vivo using photoacoustic microscopy. The study revealed that these vessels play a crucial role in regulating cerebrospinal fluid circulation and clearing metabolic waste from the brain, which is impaired in early stages of Alzheimer's disease.
Researchers from Wyss Institute and Harvard University developed a biomaterial vaccine that enhances and sustains lymph node expansion, leading to more effective anti-tumor responses. The vaccine formulation, based on microscale mesoporous silica rods, reprograms antigen-presenting cells to orchestrate complex immune responses.
Researchers at the University of Basel and NCCR SPIN have successfully coupled two hole-spin qubits, enabling fast and precise controlled spin-flip operations. This achievement is a significant milestone in the quest for practical quantum computing, with millions of qubits on a single chip.
A research team from USTC proposed a novel design approach for GRN generators, accommodating arbitrary σ values and output ranges. They introduced a scaling index to adjust relevant values differently based on varying σ values, resulting in a stable error curve and facilitating real-time configuration of σ values.
A new study published in JMIR Mental Health sheds light on the promising role of virtual reality (VR) in treating major depressive disorder (MDD). VR-Enhanced Behavioral Activation (XR-BA) was found to be effective in easing symptoms of depression, comparable to traditional behavioral activation.
Scientists have discovered DDT-related chemicals in deep-sea fish near Catalina Island, raising concerns about the persistence of toxic pollution in marine ecosystems. The contaminants are settling on the seafloor, potentially harming wildlife and human health if ingested.
Researchers at UC Santa Barbara have developed a method to produce high-quality perovskite films at room temperature, significantly increasing their efficiency from under 20% to 24.4%. This simplified process reduces energy use and lowers carbon dioxide emissions, making it suitable for flexible indoor and outdoor energy generation.
Deforestation rates accelerated in the region, with 32 municipalities and 1.7 million inhabitants under pressure. The study highlights concerns over land speculation and lack of environmental impact studies for the proposed 'Abunã-Madeira Sustainable Development Zone'.
Michele Greet will examine abstract painting emergence in Andean countries during 1950s and 1960s, exploring local aesthetics and regional cultural heritage.
The article assesses Community Outreach and Engagement initiatives at NCI-DCCs, highlighting successful programs that reduced disparities. The authors emphasize the need for sustained focus on community outreach and engagement, clinical access, and health equity to ensure everyone has access to latest scientific advances.
The University of Central Florida is establishing itself as a leader in hypersonics and space propulsion research with substantial new funding from the US Department of Defense. The funding will support the construction of a hypersonic testing facility, flight experiments and further advancements of the technology.
Researchers have developed microcapacitors with record-high energy and power densities, paving the way for on-chip energy storage in electronic devices. By engineering thin films of hafnium oxide and zirconium oxide, scientists achieved a negative capacitance effect, allowing for greater amounts of charge to be stored.
A Rutgers-led study found that supplementing standard opioid addiction treatment with Mindfulness Oriented Recovery Enhancement (MORE) can cut program dropout rates by 59 percent and relapses by 42 percent. The intervention incorporates mindfulness training, savoring skills, and cognitive reappraisal to help individuals retrain themsel...
A study published in Nature Medicine reveals that individuals with two copies of the APOE4 gene develop signs of Alzheimer's disease, with over 95% showing biological characteristics at age 65. The findings suggest a new genetic form of Alzheimer's disease, potentially leading to personalized prevention and treatment strategies.
Researchers found that inflammatory proteins peak at different times of day based on whether new mothers breastfeed or formula-feed their babies. The study's findings suggest a unique immune profile for lactating mothers and highlight the need for further research into postpartum breastfeeding.
Recent technological breakthroughs enable global insect surveys using sound recordings, images, radar, laser beams, and DNA analysis. This allows for new insights into insect trends and species identification without relying on experts or killing insects.
A new study by NYU researchers reveals that English learner status is just one factor influencing high school graduation rates, with social identities like race and gender playing a significant role. Young women who learned English in school are more likely to graduate than young men, while Black students tend to have better four-year ...