A new case study in India found that home garden interventions struggled due to verbal training, lack of demonstrations, and limited household engagement. However, flexibility and participatory techniques like Process Net-Mapping revealed positive outcomes on nutrition and sustainable agriculture practices.
Researchers identify modifiable determinants of cerebral blood flow (CBF) and arterial transit time (ATT) in older adults. A higher BMI was associated with lower CBF and longer ATT, while cardiorespiratory fitness linked to longer ATT in specific brain regions.
Researchers found that adopting popular brand nicknames can be detrimental to a company's performance, as it implies consumer control. This is because brand nicknames are often used by consumers, which can make the brand appear weaker when adopted by marketers.
The prevalence of treatment-resistant vaginal thrush has increased significantly in the UK, with a fourfold rise in fluconazole resistance between 2018 and 2021. This trend follows a shift in clinical practice, with doctors now treating on signs and symptoms rather than confirmatory lab tests.
A new study of bubbles on electrode surfaces could help improve the efficiency of electrochemical processes by understanding how blocking effects work. The findings show that only a smaller area of direct contact is blocked from its electrochemical activity, not the entire surface shadowed by each bubble.
A recent study by Imperial College London has found that dogs swimming in contaminated ponds are releasing harmful levels of two pesticide medications. The chemicals, imidacloprid and fipronil, were used as flea and tick treatments for cats and dogs, posing a significant threat to aquatic life.
Researchers will showcase results of a randomized clinical trial demonstrating Biovanta's efficacy in reducing common cold symptoms by strengthening the respiratory barrier and controlling inflammation. The presentation will also include preclinical data on antiviral formulas targeting rhinovirus and influenza.
A new study published in Journal of Biogeography finds that malaria-like blood parasites increase in prevalence with the number of bird species present, highlighting the importance of host diversity. The research also shows that parasites can spread more rapidly when they specialize in closely related or functionally similar bird species.
A Kobe University research team analyzed conditions for access to nature across generations, finding that availability of green spaces, nature-relatedness, and childhood experiences drive visits. The study highlights the importance of effective environmental education and urban planning policies to address inequalities in nature access.
Scientists discovered a unique way in which yeast cells adapt to starvation by coating their mitochondria with massive molecular complexes called ribosomes. This adaptation has potential implications for cancer treatment as it may help overcome the challenges faced by cancer cells when they are starved of nutrients.
Researchers have confirmed that El Niño causes a drastic reduction in the snow-covered area of the Quelccaya Ice Cap in the Peruvian Andes. The study used NASA Landsat satellites to measure the ice cap's sensitivity to climate shifts, finding that it lost about 58% of its snow cover between 1985 and 2022.
A new report warns of an unprecedented climate emergency, with key findings including widespread forest dieback and major ice sheet collapse. The authors emphasize the need for decisive action to safeguard the natural world and ensure a livable future.
Researchers at the University of Miami Rosenstiel School are leading a four-year project to develop best practices for decision-ready climate projection information. The team will engage stakeholders across five themes, providing access to crucial datasets and analysis procedures.
Researchers at IOCB Prague successfully isolated the proteasome enzyme complex of the T. vaginalis parasite, enabling them to develop new medicines that can target this parasite without harming humans. This breakthrough has critical implications for treating trichomoniasis and reducing HIV risk.
A recent study finds that long-term changes in tropical weather patterns are leading to increased frequency of heatwaves and extreme rainfall in the Indo-Pacific region. Global warming is likely a contributing factor, exacerbating regional weather extremes.
The system removes salt from water at a pace that closely follows changes in solar energy, maximizing the utility of solar power. It produces large quantities of clean water despite variations in sunlight throughout the day, making it an attractive solution for communities with limited access to seawater and grid power.
A new study highlights the emergence of 'just transition litigation', challenging climate policies and projects that disproportionately impact vulnerable communities. The phenomenon emphasizes the need for balancing climate action with social justice considerations, particularly for Indigenous Peoples, workers, and local residents.
The team aims to focus on 6G technology, the ultra-high frequency, high-speed successor to 5G networks. They will work to integrate three technologies into a single device to create compact electronic devices that overcome limitations to performance, functionality, size and thermal management.
New research reveals stressed bees make pessimistic choices and lack a buzz in life. They reduce their expectations of reward when agitated, which could impact how they approach and pollinate flowers.
A team of scientists developed a new method for 3D nanolithography using low peak power laser oscillators, enabling the creation of non-photosensitized materials without photo-initiators. Wavelengths of 517 nm, 780 nm, and 1035 nm are suitable for producing 300 nm polymerized features with high linear writing speeds.
A longitudinal study tracked one person's brain activity for five months, revealing how daily life affects brain function. The research found that physical activity positively influences brain regions, while subtle shifts in mood and heart rate leave lasting imprints for up to fifteen days.
A new study reveals that green education can nurture a generation of eco-leaders to tackle climate change and environmental issues in the Middle East and North Africa. The study recommends integrating sustainability into national curricula, providing sustainable funding for education initiatives, and monitoring evaluation systems.
Researchers at UC Irvine have made the first-ever atomic-scale observations of grain rotation in polycrystalline materials. They discovered that grain rotation occurs through disconnection propagation along grain boundaries.
Researchers developed a light-driven, toroidal micro-robot that can navigate complex environments like medicine and environmental monitoring. The innovation uses liquid crystalline elastomer to overcome viscous forces and enables autonomous movement in low Reynolds number regimes.
Researchers have identified a critical genetic group that is near incurable using current therapies, leading to improved survival and quality of life for children with Group 3 medulloblastoma. The study also uncovered a potential targetable mechanism for new therapies aimed at improving outcomes.
The two-year study aims to explore biases in AI systems and develop a 'human-in-the-loop' framework for quality data discovery. It will investigate how humans can be involved as labelers, prompters, and validators to improve data sets and user interfaces.
Researchers have discovered a new plant seed fossil, Alasemenia, which provides insight into the origin and early evolution of wind dispersal strategies in plants. The study found that Alasemenia's three-winged seeds are more adapted to wind dispersal than one, two, or four-winged seeds.
A new technique called Clonal competition assays helps understand the evolutionary advantages of multiple myeloma cells over available treatments. It allows researchers to see how each population of cells in the same myeloma reacts to treatments, getting closer to understanding heterogeneity and resistance.
A cognitive behavioural therapy (CBT) app has been found to significantly prevent increases in depression in young people who are at high risk of developing the condition. The study, which involved over 3,700 participants across four countries, suggests that the CBT app can be an effective public health measure.
A UC Irvine-led team has engineered an efficient new enzyme that can produce synthetic genetic material called threose nucleic acid. This advancement advances the discovery of potentially more powerful, precise therapeutic options for cancer and autoimmune diseases.
A global analysis of new cancer drug launches between 1990 and 2022 found significant disparities in availability and timeliness, with poorer countries missing out. The gap between rich and poor nations widened over three decades, suggesting such inequities may explain poor cancer outcomes in many lower-income countries.
A circular bioeconomy aims to reduce waste, transform industries, and regenerate natural systems for environmentally sustainable food and energy production. The concept needs a values-based economic lens with the right policies and incentives to persuade consumers and producers.
A team from UNIGE and EPFL has demonstrated the Entropic Pulling mechanism of Hsp70 chaperones, a long-debated theory that explains their role in controlling protein quality. The study uses nanopore single-molecule technology to show that Hsp70s generate a strong force to manipulate protein structure, ruling out previous models.
A new study found that individuals' willingness to cooperate in one-time situations is remarkably stable, regardless of the potential benefits. Across two experiments involving over 2,000 participants, the researchers found no significant change in cooperation rates when benefits were increased.
A study found that patients with hip fractures who wait over 4 hours for treatment in emergency care are at higher risk of death and longer hospital stays. The researchers analyzed data from a single trauma center in Scotland, where over 1 in 3 patients waited longer than the required standard time frame.
A recent study published in Knee Surgery, Sports Traumatology, Arthroscopy found that children who undergo surgery for discoid lateral meniscus are at higher risk of developing further knee injuries with age. Younger patients were particularly prone to relapse after surgery.
Scientists at The Wistar Institute have identified a novel series of SARS-CoV-2 Mpro inhibitors that effectively inhibit viral replication in vitro against multiple COVID variants. These compounds also synergize with existing antivirals, offering promise for developing future therapies.
Researchers found that DOCK8 mutations disrupt glycolytic pathway in CD4+ T cells, impairing their differentiation and immune function. This study highlights the importance of metabolic flexibility in immune cell function and suggests new treatment strategies.
A new study reveals that some Medicare Advantage plans engage in strategic cross-subsidization, offering extra benefits to healthier patients while providing fewer benefits to sicker patients. This practice can lead to reduced care quality for vulnerable populations and exacerbate socioeconomic inequalities in healthcare access.
A new study from UCSF has found that ChatGPT overprescribes in emergency care situations, providing unnecessary x-rays and antibiotics. The AI model was less accurate than resident physicians, with a tendency to err on the side of caution. Researchers emphasize the need for better frameworks to evaluate clinical information before AI c...
The 2024 State of the Climate Report reveals a 'critical and unpredictable new phase of the climate crisis,' with many planetary vital signs at record extremes. The report highlights urgent policy changes needed in energy, pollutants, nature, food, and economy to mitigate catastrophic climate change.
The painting in the La Belle France cave is believed to be the world's oldest known piece of paleo-art depicting an extinct mammal-like reptile called a dicynodont. The San people were engaging in palaeontology long before Western scientists, and their artwork provides compelling evidence of this.
Researchers from King's College London have created a new kind of compact circuit that enables robots to receive complex instructions without electricity. This breakthrough could enable the creation of robots with more complex AI-powered software and improve their social awareness and dexterity.
Researchers at Baylor College of Medicine have discovered DAPK3 as a key regulator of TNBC cell migration. The study found that eliminating DAPK3 protein leads to prevention of migration and invasion in laboratory experiments. Further studies are needed to assess its potential value as a therapeutic target.
Researchers found that intestinal absorption of fats plays a crucial role in preventing diet-induced fatty liver disease. The absence of gut hormones, such as proglucagon-derived peptides, prevents fat accumulation by reducing lipid absorption from the intestines.
Researchers at MPI unveiled PLK1's crucial role in replenishing CENP-A proteins per centromere, a process critical for cell division. PLK1 initiates a cascade of events by binding to specific machinery components and inducing phosphorylation changes.
A new study found that lower-income adults with Medicare Advantage plans struggling to pay for dental, vision, and hearing services despite coverage. Higher-quality plans had better dental coverage, but not for hearing and vision.
Researchers evaluated HIV reservoir in breast milk cells of two women living with HIV, detecting very low levels of cellular HIV DNA. The study's findings support revised recommendations on infant feeding by people with HIV in high resource settings.
Researchers from Tohoku University developed a novel method to produce hydrogen using ultrafine Rh-Cr mixed-oxide cocatalysts with facet-selective loading. This approach achieved 2.6 times higher water-splitting photocatalytic activity, paving the way for a more abundant, green energy source.
Researchers at George Mason University are developing an AI-powered system to predict snow water equivalent (SWE) forecasts, utilizing graph neural network-based models and physics-based constraints. The project aims to create more accurate and reliable SWE forecasts by capturing detailed snow accumulation and melt processes.
A case study of a 65-year-old woman with scurvy highlights the need to consider vitamin C deficiency in patients with restrictive eating patterns and limited social support. Vitamin C deficiency is more common than expected, especially among those with low socioeconomic status or substance use disorders.
A UBC study analyzing pedestrian interactions with vehicles on busy streets found that distracted pedestrians face higher safety risks compared to undistracted road users. Distracted pedestrians remained unaware of their surroundings, making fewer adjustments to their path or speed.
A UCLA team has unveiled a powerful tool to overcome limitations in CAR-T cell therapy by mimicking natural interactions between immune cells. The new platform facilitates a high capacity for stimulating T cells to reproduce while preserving their versatility and potency.
Researchers created SmartCADD, an AI-powered virtual tool combining quantum mechanics and Computer Assisted Drug Design techniques. The tool speeds up the screening of chemical compounds, significantly reducing drug discovery timelines and identifying promising HIV drug candidates.
Researchers used instruments on board Curiosity to measure the isotopic composition of carbon-rich minerals and discovered extreme evaporation, suggesting a climate that could only support transient liquid water. This finding rules out life on Mars' surface but leaves open the possibility of an underground biosphere.
A new study by Stanford Medicine found that upgrading emergency departments to be more prepared for pediatric care could save children's lives and reduce costs. The research team analyzed data from hundreds of hospitals in 11 states and found that doing so would cut deaths of pediatric emergency patients by almost half.
A new study found that common breast cancer treatments, including chemotherapy, radiation, and surgery, can increase expression of aging markers in breast cancer survivors. The study suggests that these treatments can have a more extensive impact on the body than previously thought, leading to accelerated biological aging.
A recent study found that psychiatric drugs are 50% more effective in clinical trials funded by the manufacturer compared to those sponsored by other groups. The researcher attributed this phenomenon to the sponsorship effect, which is reduced by 20% when unpublished trials are included in the analysis. Preregistration has helped reduc...
Damage to the brainstem, the brain's control centre, is behind long-lasting physical and psychiatric effects of severe Covid-19 infection. Researchers used ultra-high-resolution scanners to observe the damaging effects of Covid-19 on the brain, finding inflammation in key regions associated with breathlessness, fatigue and anxiety.
Recent clinical trials of neoadjuvant therapy before radical prostatectomy, such as the ACDC-RP trial, have struggled to show significant survival benefits. Researchers recommend maximal androgen blockade with an androgen receptor pathway inhibitor as the 'backbone' of neoadjuvant therapy trials.