A new study by University of Exeter researchers calls for reforms to protect adults from exploitative litigation in copyright enforcement. The study recommends more rigorous checks and balances on copyright infringement actions, prioritizing the protection of sexual privacy.
A study at the University of Texas M.D. Anderson Cancer Center found that adding CTLA-4 immune checkpoint inhibitors to durvalumab and chemotherapy improved overall response rates, progression-free survival, and overall survival for patients with metastatic non-squamous non-small cell lung cancer harboring STK11 and/or KEAP1 mutations.
A new citizen science study has found that a person's subjective impression of their own memory problems is strongly linked to modifiable risk factors for dementia. The research used a smartphone app to gather data from 3,327 people and found a stronger association between subjective memory impairment and risk factors such as depressio...
Researchers at the University of Colorado Boulder have developed a new quantum timekeeper that combines four different clocks into one, allowing for increased precision. The device uses entanglement to reduce uncertainty in its ticking, enabling it to beat benchmark standards for optical atomic clocks.
Research highlights significant growth in global cervical cancer research output, particularly in China, where hotspots focus on pathogenesis, epidemiology, HPV vaccination, and screening strategies. International cooperation and public health awareness are emphasized as key areas for improvement.
Researchers found that rising temperatures accelerate weathering of rocks in the Canadian Arctic, leading to increased CO2 release and a positive feedback loop. This process could contribute significantly to climate change, with predicted emissions doubling by 2100 under moderate emission scenarios.
Researchers developed an electronic tongue that can identify differences in liquids and detect food safety concerns. The AI-powered system achieved high accuracy when using its own assessment parameters, providing insights into the neural network's decision-making process.
A new study from Karolinska Institutet found that people with type 2 diabetes have lower levels of the protein creatine kinase, leading to impaired mitochondrial function and energy production. This impairment may contribute to poorer energy metabolism in individuals with type 2 diabetes.
Researchers found inhibiting ACMSD increases NAD+ levels, reducing inflammation and fibrosis in mouse models of MASLD/MASH. Boosting NAD+ production could protect against severe liver damage and cirrhosis.
Researchers developed AI chatbot UroBot to answer complex urology questions with high accuracy, exceeding human urologists. The model justifies its answers based on European Society of Urology guidelines and has been tested on 200 specialist questions, achieving an accuracy rate of 88.4%.
A new study uses insect evidence from illegally killed rhinos to determine the post-mortem interval. This technique has been used to construct cases against poachers and has led to a rebound in rhino populations over the past 30 years.
Researchers have developed a cell culture platform to form two distinct, interconnected vascular networks, replicating human physiology and reducing animal testing costs. This breakthrough enables the study of cellular interactions in vascularized tissues.
A study found that screening frequency and breathing trial techniques did not affect the time to successful extubation. However, a combination of more frequent screening and pressure-supported SBTs increased the time to first successful extubation.
A study from the University of Kansas found that parents trust AI-generated text, like ChatGPT, more than healthcare professionals' content. Parents rated ChatGPT as more trustworthy, accurate, and reliable in many cases, even when there were significant differences in ratings.
A new study found an association between some types of cancer and multiple sclerosis (MS), with people with MS having a 6% increased risk of developing any type of cancer. The study identified higher risks for bladder, brain, and cervical cancers, but lower risks for prostate, colorectal, and breast cancers.
Researchers successfully designed and engineered novel enzyme systems that can degrade various types of plastics. By replacing the binding module with different modules, they created chimera LPMOs capable of recognizing and breaking down different types of plastics, including biosourced polyhydroxyalkanoate.
A research team discovered that the Rickettsia symbiont induces cytoplasmic incompatibility (CI) in the mirid bug, affecting its reproductive biology. This finding has significant implications for effective pest management and highlights the importance of assessing CI frequency in wild populations.
A significant gender rating gap has been discovered in online reviews, with women's average ratings significantly higher than men's, driven by societal pressures to avoid backlash. The researchers emphasize the need for platform changes and societal shifts to create conditions where people feel comfortable sharing their true experiences.
Aerobic physical activity was associated with modest short-term and long-term reductions of depression among adults with cancer. The study suggests that aerobic exercise may be an effective strategy for managing depression in cancer patients.
Studies discovered that DNA sequence changes associated with diabetes predisposition alter pancreatic cell stress response, leading to reduced insulin production and increased cell death. The findings point toward a druggable target, MAP3K5, which may help prevent or treat type 2 diabetes in high-risk individuals.
Recent research highlights microwave-induced synthesis as a transformative potential in drug discovery and development. This efficient technique enables rapid preparation of diverse N-heterocycles, including biologically active molecules such as pyrimidines, thiazoles, and quinolines.
Industry-sponsored trials have grown while federally funded enrollment remains flat, jeopardizing research in cancer prevention, screening, and health disparities. Diversified funding and strong advocacy are needed to ensure all patient populations benefit from research advancements.
Researchers have discovered various ways to optimize electrocatalytic reduction reactions by tuning the type and concentration of cations, improving their activity, selectivity, and efficiency. The study provides a comprehensive overview of cation effects on catalytic reduction reactions, highlighting both opportunities and challenges.
Researchers used neutron tomography to analyze Iron Age bronze Iranian swords, detecting glue and modern tools used to alter their value. The study highlights the prevalence of modern tampering in antiquities trafficking, with implications for heritage crime and museum collections.
A new study in the American Journal of Preventive Medicine found that quitting smoking even at 75 can significantly increase life expectancy. The research showed that older individuals who quit smoking can avoid an average loss of 4-9 years of life, with some regaining up to 8 years or more.
Scientists create synthetic biology approach to mechanistically study tissue patterning and engineer organoid structures by combining morphogens with cell adhesion control. The model system reveals a key feature of E-cadherin for forming sharp boundaries in synthetic tissue domains.
Concordia researchers develop a novel method of 3D printing using acoustic holograms, capable of creating complex objects quickly and at once. This technique, called holographic direct sound printing (HDSP), stores information of multiple images in a single hologram, allowing for the creation of multiple objects simultaneously.
A new study found that babesiosis rates rose 9% annually between 2015 and 2022, with 42% of cases linked to other tick-borne illnesses. Co-infection with Lyme disease did not increase mortality risk, but patients received doxycycline treatment more frequently.
The ASU-led initiative, EPIXC, aims to develop cost-effective technologies to replace fossil fuel-based industrial process heating with clean electricity. Five jump-start projects were selected to advance innovations in electrified industrial process heating, covering various sectors and temperature ranges.
Researchers analyzed changes in 72 pairs of microRNAs in patients' blood extracellular vesicles before and after radical prostatectomy, identifying significant changes in 11 miRNA ratios. The study suggests a potential new biomarker for monitoring treatment efficacy and predicting cancer relapse.
Researchers at University of Göttingen studied Bronze Age spear combat using multi-stage experiments to understand fighting styles and mark formation on spearheads. The study provides insights into wear formation, trauma, and combat contexts, benefiting future research and museum curation.
The WVU STARS-UP program pairs two-year colleges with nearby four-year institutions to provide astrophysics and astronomy research opportunities. The goal is to create a sustainable pipeline for careers in STEM, focusing on underrepresented students from low socioeconomic communities.
A new theoretical strategy enables the creation of asymmetric continuous distributions with tunable parameters and various shapes. This improvement can increase accuracy in models and predictions, particularly for skewed or multimodal data.
Researchers create Lewy bodies in living dopaminergic neurons using human stem cells and find that immune challenge is crucial for their formation. The study identifies a previously unknown link between the immune system and neurological disease, suggesting that genetic predisposition may not be necessary for Parkinson's development.
A University of Barcelona team has designed a drug capable of acting against three different therapeutic targets in breast cancer cells. The new compound, based on oligonucleotide-based drugs, successfully inhibits the expression of key proteins contributing to poor prognosis and drug resistance.
The publication of the Malleus maleficarum in 1487 played a crucial role in spreading persecution across Europe, with each new edition leading to an increase in witch trials. Social influence, particularly from neighboring cities, also contributed to the spread of witch-hunting practices.
A new scoring system helps doctors predict which patients will likely become seizure-free after minimally invasive epilepsy surgery. The model is based on eight clinical factors and has been shown to outperform other predictive models in predicting seizure freedom.
The World Innovation Summit for Health (WISH) will tackle global health issues like antibiotic resistance and conflict zones through keynotes from Lord Ara Darzi and Christos Christou. More than 200 experts will present innovative practices in healthcare.
A new algorithm, Modified Metroticket, has been developed to predict overall survival and recurrence-free survival in patients with intermediate-stage liver cancer. The tool takes into account tumour burden, biological aggressiveness, liver function, and age, and has been validated using local and international datasets.
A recent survey by the Crohn's & Colitis Foundation found that over 40% of IBD patients have made substantial financial trade-offs to access their care. Among these respondents, 22% increased their credit card debt, while 21% cut back on essential items like food and clothing.
A team of HKU chemists has made a breakthrough in combating antibiotic-resistant bacteria by combining bismuth-based drugs with antibiotics. This synergistic approach disrupts bacterial iron homeostasis, effectively eliminating multi-drug resistant Pseudomonas aeruginosa infections.
Researchers from Ruhr University Bochum have gained new insights into the operation of an iron catalyst that can split ammonia into nitrogen and hydrogen. The team's findings enable more efficient catalysts for ammonia decomposition, paving the way for a promising energy carrier transport solution.
Researchers from USC and Caltech develop a new method to study hematopoietic stem and progenitor cells within the bone marrow without extracting them. This breakthrough could inform efforts to optimize bone marrow transplantation and provide insights into various health conditions, including cancer and heart disease.
Researchers have developed a novel gene therapy approach that targets and breaks down faulty ribonucleic acids in the KCNA2 gene, which is associated with recurring seizures. The therapy has shown promise in reducing excessive neuron activity linked to epilepsy.
This study analyzed soil VOC levels and their correlation with soil physical properties, ionome, microbiome, metabolome, and rhizosphere chemicals. The results reveal that soil VOC profiles can be reliable indicators for evaluating soil health in agricultural environments.
Researchers argue that AI's impact on public health depends on its development and deployment, warning of potential biases, lack of transparency, and exacerbation of existing harm. However, the authors also highlight AI's potential to improve healthcare systems, access to care, and provide essential services.
The study found that adding fall blooming plants can alleviate stressors on wild bees caused by developed land and urban beekeeping. Planting late-season forage and leaving bare ground as nesting resources can help.
A new image processing strategy for cardiac magnetic resonance imaging identifies areas responsible for complex ventricular tachycardias, enabling preoperative planning and reducing procedure times and complications. The systematic approach eliminates operator bias and increases sensitivity for detecting these regions.
New research from Binghamton University reveals that Mexican jumping bean larvae respond differently to various lighting conditions, with red light stimulating the most vigorous jumps. However, damage to their 'bean' hosts hinders their ability to jump away from stressors.
The study reveals a positive trend in scientific production on sustainability topics, with the US leading research. Academic clusters focus on education for sustainable development, engineering education, and environmental projects. Higher education is strongly committed to sustainability, aligning programs with SDGs.
A study of 668 infants found a small decrease in birth weight for gestational age with every 1°C increase in average daily heat stress during the first trimester. Infants up to two years old exposed to high heat may have lower weights and heights for their age.
Researchers describe the existence of the paradoxical Mpemba effect within quantum systems, bridging Aristotle's observations and modern-day understanding. The discovery opens doors to 'cool' implications for thermodynamic frameworks and applications in quantum technologies.
The researchers combined an NV diamond with a laser diode in an optical resonator, successfully demonstrating the sensor system with two active media. This breakthrough enables high-contrast sensors to measure biomagnetic signals from the brain or heart with improved sensitivity and dynamic range.
A study reveals a global unconformity, or gap in the rock record, around the edges of every continent at the time of the greenhouse-to-icehouse climatic transition. The finding challenges traditional ideas about sediment movement and accumulation in deep oceans.
Hospitalizations involving alcohol withdrawal syndrome (AWS) are a significant concern, especially in high-risk individuals. The study found that AWS burden is comparable to complications of other chronic diseases.
Researchers have developed two smartphone apps that provide safe indoor navigation, route guidance, and return to a previous location. The apps use built-in sensors, such as accelerometers and gyroscopes, to track the user's progress, reducing reliance on visual cues.
Researchers found that positive expectations lead to increased activity in pleasure-related brain regions, while negative expectations prime pain processing. The study suggests a dissociable impact of hedonic information, with positive expectations facilitating reward processing and negative expectations heightening anxiety.
Research finds a global imbalance in hydro-hazard studies, with more funding in wealthy regions despite greater disaster impacts in low-income areas. The study calls for more targeted research efforts to address this disparity and reduce the impact of future disasters.
Researchers have gained new insights into the interaction between membrane proteins Vipp1 and PspA and their role in protecting vital cellular processes. The study reveals that these proteins form carpet-like structures, ring complexes, and tubes to stabilize and repair damaged cell membranes.
A new study reveals a significant correlation between the decline of jumbo squid and the disappearance of sperm whales from the region. The research suggests that sperm whales play a crucial role in controlling energy flow within marine ecosystems, highlighting their importance as indicators of oceanic health.