A study by University of Exeter researcher Dr Pedro Perfeito da Silva explores the impact of popular resistance and union support on economic policies in Ecuador and El Salvador. The findings suggest that administrations reliant on strong public backing implemented stricter capital controls, while those with less support adopted more n...
Researchers have identified liver X receptor beta as a promising target for treating depression and anxiety, with key findings including LXRβ's role in regulating neurotransmission and neurogenesis. This breakthrough could lead to novel therapies for treatment-resistant depression and personalized medicine approaches in psychiatry.
Researchers investigate how pollutants affect pollinators' ability to recognize flower scents and how neural circuits adapt to temperature fluctuations in organisms like the roundworm. The study focuses on understanding resilience mechanisms that enable animals to cope with environmental changes.
A study from Goethe University Frankfurt reveals that venomous crustaceans, specifically remipede crabs in Mexican cenote caves, contain a variety of toxins with pharmacological potential. The xibalbines peptides effectively inhibit potassium channels and activate signaling pathways involved in pain sensitization.
Recent studies have found that large AI language models are becoming increasingly unreliable, failing to match human expectations on task difficulty. The models excel in complex tasks but struggle with simple ones, leading to a mismatch between human perception and model performance.
A recent study suggests that the observation of antihelium nuclei in cosmic rays may be consistent with the existence of WIMP particles, which could make up dark matter. The detection of two distinct isotopes, antihelium-3 and -4, is particularly intriguing as heavier nuclei are unlikely to be produced through natural processes.
Researchers at Michigan Medicine have discovered a new subtype of aggressive prostate cancer and identified a potential degrader to target it. The study found that a genetic alteration in the CDK12 gene drives cancer development, and a degrader targeting this gene shows promise in destroying cancer cells.
A new study by NYU researchers reveals that more than 60% of the US population has access to certified community behavioral health clinics, which provide mental health and substance use disorder treatment services. The clinics are expanding crisis mental health services, including mobile crisis response teams and stabilization.
The CityUHK team develops a new federated learning technology integrated with research knowledge graphs and large language models to digitally transform STI services. This will create a comprehensive, domain-specific knowledge base and provide intelligent assistant services for researchers.
A new study identifies phosphatidylinositol 4,5-bisphosphate as a key regulator of the SK2 channel, which plays a critical role in cardiac ion channels and heart rhythm. The research provides critical translational insights into possible mechanisms of cardiac arrhythmias in heart failure.
A new mechanism of DNA damage response has been identified, involving an RNA transcript that regulates genome stability. The study found that NEAT1, a long non-coding RNA transcript, plays a crucial role in recognizing and repairing DNA double-strand breaks.
Researchers found that brain shrinkage patterns vary significantly among individuals with Alzheimer's, with some accumulating more outliers over time. This variability could enable the development of targeted treatments and predict future symptoms.
A study published in Strategic Management Journal found that high-tech firms with powerful, experienced boards experience a 113% increase in breakthrough innovations. The research team highlights the importance of balancing CEO overconfidence with board expertise and power.
Two new papers estimate economic value of reducing avoidable deaths worldwide, finding 40 million deaths in 2019 were avoidable. The economic value is equivalent to 23% of annual global income, suggesting health improvements could lead to substantial economic benefits.
A Canadian study finds that treatment for vulnerable people with endocarditis includes in-hospital addiction support and community care, with special attention to the needs of marginalized young women. Women who inject drugs are disproportionately affected by endocarditis and have higher long-term mortality rates than men.
The University of Houston-led project aims to provide training and resources for jobs in the new hydrogen economy, prioritizing underserved communities. The team will create a publicly available online toolkit to facilitate community engagement and equitable access to emerging jobs.
Scientists have found a way to pinpoint single bacteria that are resistant to antibiotics, making it easier to choose the right treatment. This breakthrough could lead to improved treatment outcomes for patients with Staphylococcus aureus infections.
Researchers at LSU and Smithsonian Institution found that ants began farming fungi after an asteroid struck Earth 66 million years ago. This behavior is still exhibited by some ant species today.
A recent study explores the potential of AI in ophthalmology to detect elevated HbA1c levels, a marker for high blood sugar and cardiovascular disease. The research highlights the importance of developing trustworthy AI models and addressing challenges in clinical adoption.
Researchers found that geckos utilize the saccule, a part of their inner ear traditionally linked to balance, to detect low-frequency vibrations. This 'sixth sense' plays a complementary role in the geckos' normal hearing and sensory perception.
The study highlights the critical role of online pharmacies in providing direct-to-patient medication abortion care, particularly with virtual-only platforms. Removing barriers to accessing these services is crucial for increasing accessibility and equality in reproductive healthcare.
The Society for Neuroscience is supporting 445 neuroscience trainees to attend Neuroscience 2024 through the Trainee Professional Development Award program. The 2024 recipients include a record-high representation of non-U.S. and female trainees, with funding provided by numerous donors and foundations.
Research by LMU scientists suggests that large-scale afforestation and reforestation could significantly influence the climate, reducing peak temperature by 0.08°C and end-of-century temperature by 0.2°C. The study also finds that AR can shorten the time during which global temperature overshoots the 1.5-degree target by 13 years.
Researchers identified AM-101 as a potential new way to enhance radiation therapy for patients with lung cancer that has spread to the brain. The drug's ability to activate GABA(A) receptors increases autophagy in lung cancer cells, making them more sensitive to radiation treatment.
Researchers at KIT have controlled tin-vacancy center qubits in diamonds using microwaves, achieving coherence times of up to ten milliseconds. This is a major improvement for the development of diamond-based quantum computers and secure fiber-based quantum communication.
Researchers found the phrase has broadened to include regional inequalities in state services and poverty, with varying meanings for different people. The study, carried out by Grace Redhead and Rebecca Lynch, highlights the complex causes of regional inequality in health and healthcare.
Researchers have developed a new treatment for deep diabetic foot ulcers, using intact fish skin grafts to promote healing. The study found that this innovative approach showed promising results in improving wound closure and reducing infection rates.
A new experimental blood test, combining CA199.STRA and CA19-9 biomarkers, improves accurate detection of pancreatic cancer in a lab setting by 27%, according to a recent study published in Cancer Letters. The test's effectiveness in a clinical lab setting is crucial for approval as a potential diagnostic method.
Researchers developed a novel optical computation architecture called diffraction casting, which leverages spatial parallelism of light to perform computations. This method overcomes limitations of previous techniques by using wave optics, enabling scalable and parallel logic operations with high flexibility and integration capability.
The US employment-to-population ratio for people with disabilities rose to 37.5% in September 2024, marking a positive trend after three months of stability. Meanwhile, labor force participation rates remained near historic highs, reflecting ongoing efforts to improve accessibility and flexibility in the workplace.
A new study reveals that poor winter habitat conditions in the Caribbean can lead to reduced survival rates during spring migration and the breeding season for migratory songbirds. Climate change is expected to further exacerbate these effects, underscoring the need for conservation measures to protect vulnerable species.
Researchers at the University of Bonn and Montreal developed a new catalyst that produces methane out of carbon dioxide and water in a highly efficient way using electricity. The process has an efficiency of over 80 percent and produces few side products.
Marine heatwaves in UK waters have been characterized for the first time, revealing regional variability and seasonal differences. The southern North Sea and English Channel tend to experience longer and moderately intense heatwaves, while the eastern North Sea has shorter but more intense heatwaves.
A study published in Blood reported high response rates of 89% and complete responses of 70% among patients with relapsed or refractory multiple myeloma who received cilta-cel infusions. The results were comparable to those seen in clinical trials, suggesting the therapy's effectiveness in real-world settings.
Researchers have made breakthroughs in creating nanoparticles that can modify the immune system to accept transplanted organs without compromising it. This new approach has potential implications for treating diabetes, cell therapy, and autoimmune disorders, offering hope for patients who currently face rejection.
The study reveals that the Tartessians' use of earthen construction was a highly adapted and sustainable approach, particularly in local environmental contexts. This achievement highlights their advanced architectural skills and underscores their ability to build in harmony with nature.
The Society for Neuroscience has announced three Gold Sponsors of Neuroscience 2024: Johnson & Johnson, Ncardia, and Nxera Pharma. These organizations will be recognized throughout the event for their support.
A high-fat diet can promote overweight and increase diabetes risk, but fat alone does not change the brain's hypothalamus. Other macronutrients like sugar may have more profound effects on AgRP neurons.
A new article investigates whether auditory magic tricks can be created for a blind audience, finding that the brain processes visual and auditory information differently. This study underscores the importance of making magic more inclusive for people with blindness.
Researchers have successfully tested a new drug, trastuzumab deruxtecan, which significantly extends the lives of breast cancer patients with advanced HER2-positive disease and brain metastases. The treatment has been shown to increase survival times substantially, with over 90% of patients alive one year after treatment.
A cross-sectional study found that US adults with social risk factor domains were less likely to receive preventive services. The association was cumulative, emphasizing the importance of addressing these factors to optimize healthcare outcomes.
A new study found that completing a six-month substance use disorder treatment program instead of arrest and prosecution reduces the risk of arrest, incarceration, or fatal overdose. Participants who completed the program had a more favorable crime and overdose profile compared to those who did not engage or complete the program.
An international team produced global maps of the coronal magnetic field using a new instrument called UCoMP. The observations are providing valuable insights into the processes that drive intense solar storms impacting technologies and lives on Earth.
Researchers successfully couple two Andreev qubits mediated by a microwave resonator, enabling long-range exchange of quantum information. The study demonstrates the potential of Andreev pair qubits as compact and scalable solid-state qubits for reliable quantum computing.
A retrospective cohort study found that AI algorithms can identify women at high risk of developing breast cancer 4-6 years before detection. The results suggest using commercial AI algorithms as a pathway to personalized screening approaches, leading to earlier cancer diagnosis.
An interdisciplinary study found associations between exposure to environmental phenols like BPA and triclocarban and altered cardiac electrical activity, particularly in women with higher body mass indexes. Researchers identified moderate changes to cardiac electrical activity that could exacerbate existing heart disease or arrhythmias.
Research shows that increased bean and pulse consumption is associated with higher diet quality scores and greater intake of shortfall nutrients. Adding one- or two-servings of beans daily can significantly increase dietary fiber, potassium, magnesium, iron, folate, and choline intake.
Two UMD Astronomy space probes, AXIS and PRIMA, have advanced to the next round of consideration for a $1 billion NASA mission. AXIS will study X-rays from stars and black holes, while PRIMA will explore far-infrared radiation to understand galaxy formation.
A new study by Cornell University finds that liquefied natural gas (LNG) exported from the US has a one-third larger carbon footprint than coal when considering processing and shipping. LNG's extraction, processing, transportation, and storage account for approximately half of its total greenhouse gas footprint.
Astronomers have discovered a galaxy with an unusual light signature, suggesting it may be a missing link between the universe's first stars and familiar galaxies. The galaxy's gas is outshining its stars, indicating extreme conditions that could provide insights into early galaxy evolution.
Researchers found that zinc supplements can inhibit the transfer of AMR plasmids, reducing the spread of antibiotic-resistant infections. The study provides hope for developing an inexpensive and effective method to combat the growing threat of antimicrobial resistance.
Researchers at the University of Arkansas propose a new explanation for the observed pattern: statistical noise. The study suggests that 'noise' creates a misleading hyperbolic pattern, making it seem like evolutionary rates increase over shorter time frames.
Researchers found that people rate AI-generated headlines as less accurate and share them less, regardless of truthfulness. The effect is smaller than labeling false content, suggesting skepticism due to assumptions of full AI automation.
Researchers have developed a promising new drug, RI-AG03, that successfully targets and blocks both major aggregation-promoting 'hotspots' of the Tau protein. The peptide-based approach shows significant potential in preventing the build-up of Tau proteins and neurodegeneration, addressing a critical gap in current treatments.
A new study reveals the true global impact of human-induced species loss is far greater than previously thought, resulting in a loss of approximately 3 billion years of unique evolutionary history. This extinction crisis has severe consequences on ecosystem function, including reduced pollination, seed dispersal, and disease outbreaks.
A new non-invasive imaging technique has been shown to accurately detect clear-cell renal cell carcinoma, the most common form of kidney cancer. The technique uses a monoclonal antibody drug that targets the protein CA9, highly expressed in up to 95% of clear cell kidney cancers.
A study by TIFR Mumbai and collaborators has identified the ventral hippocampus as a critical brain region in mediating the anxiolytic effects of psychedelics like DOI. The researchers found that targeting parvalbumin-positive interneurons in this region is key to reducing anxiety behavior.
A new study reveals that ant agriculture and fungus farming originated 66 million years ago, with colonies of ants beginning to cultivate fungi in the aftermath of the asteroid impact. This partnership has evolved over time, with some fungal crops becoming completely reliant on ants 27 million years ago.
Researchers found that people with schizophrenia who experience auditory hallucinations have impaired brain processes, including a 'broken' corollary discharge and 'noisy' efference copy. This impairment may contribute to the loss of ability to distinguish reality from fantasy.
Researchers propose a new approach to reduce the tradeoff between overhead and protecting machines against vulnerabilities. The 'Vulnerability-Adaptive Protection Paradigm' applies different protection strategies to different parts of the system, allocating resources more wisely.