A University of North Florida biologist has received a four-year NIH grant to investigate the functional role of dual-specificity phosphatase 4 (Dusp4) in skeletal muscle atrophy. The study aims to characterize Dusp4's role in modulating muscle size and strength.
The five-year project, 'Advancing Career Choices for Employment Success in Technology,' will provide career counseling, work-readiness skills training, and customized-training leading to certified skills in cybersecurity, cloud computing, and more. The program aims to foster a diverse workforce and drive innovation in the tech industry.
A Spanish study found that the influenza vaccination campaign for children aged 6-59 months was effective in preventing acute respiratory infections and hospitalization. The study estimated the vaccine to be 70% effective against any influenza type and 77% effective against severe cases.
University of Rochester researchers have refined a noninvasive method called BL-OG that harnesses light to activate neurons in the brain. The technique has the potential to transform invasive procedures used to treat Parkinson's disease and other neurological conditions by providing a safer, less invasive alternative.
A new study explores a promising combined therapy for multiple sclerosis, using tolerogenic dendritic cells modified with myelin antigens. Researchers found that these cells from patients have a persistent pro-inflammatory signature, making them less effective compared to those derived from healthy individuals.
Researchers found that plants use both DDM1 and RNAi to control chromosome division, providing a 'backup plan' when one molecule is lost. This discovery may lead to better treatments for human diseases such as ICF syndrome and cancer progression.
A study published in Science reveals that ancient asteroid impact may have led to the evolution of fungus-farming ants, which were able to cultivate fungi due to a shortage of food sources. The findings support the hypothesis that this relationship defines the emergence of agriculture.
Iowa State University researchers are using additive manufacturing, also known as 3D printing, to create tungsten shields and components that can withstand high temperatures and radiation in nuclear reactors. The goal is to improve the efficiency of nuclear power and reduce costs.
The study reveals that water ice is present in permanently shadowed regions outside the South Pole, with concentrations expected near coldest locations and poleward-facing slopes. The research provides maps and surface characteristics to identify where ice is likely to be found, aiding lunar mission planners.
The new funding supports the first-of-its-kind single-cell mass spectrometer in Maine and one of the first in the country. Researchers can now analyze proteins and metabolites from individual cells, providing unprecedented detail into disease mechanisms.
Researchers discovered compounds Everlastin1 and Everlastin2 inhibiting EPH1, a transcription factor regulating plant flower longevity. These compounds prolonged morning glory flowers' lifespan by approximately twofold when dissolved in water.
A recent study, led by Colorado State University researchers, sheds new light on the complex interactions between plants, microbes, and soil nutrients in the Arctic. The findings suggest that long-term changes to the soil can impact carbon storage, with shrubs potentially contributing to keeping more carbon in the ground.
Researchers have discovered living microbes in a 2-billion-year-old rock sample from the Bushveld Igneous Complex in South Africa. The team used advanced imaging techniques to confirm the presence of indigenous microorganisms, shedding light on the early evolution of life on Earth and the potential for similar organisms to exist on Mars.
Researchers found that AI-generated essays are most similar to those written by male students from higher socioeconomic backgrounds and private schools. The writing styles also tend to be less varied than human-written essays, with AI favoring longer words and affiliations.
A new study at Columbia University Mailman School of Public Health found that MPH programs provide key competencies demanded by employers, but graduate employability could be improved by using more real-time data from employer job postings. The study revealed labor market competition for public health degree graduates and technical ski...
A new publication provides essential guidance for conducting rigorous systematic reviews on studies with animals and cells. Regular narrative reviews are prone to biases, but systematic reviews follow a rigorous and transparent methodology, helping researchers make sense of conflicting reports and identify gaps in the field.
A recent study by UC San Francisco and the University of Michigan found that childhood trauma can lead to increased pain, depression, and loneliness in older adults. Participants who experienced more traumatic events were more likely to experience these symptoms during their final years.
A recent study published in The Lancet Public Health found that body weight is a significant factor in pregnancy complications, affecting women born in different countries. Researchers estimated that approximately half of all cases of gestational diabetes could be prevented if all women were of normal weight during pregnancy.
Researchers developed a microchip that captures exosomes from blood plasma to identify signs of lung cancer, achieving 10x faster detection and 14x greater sensitivity. The chip uses twisted gold nanoparticles to distinguish between healthy patients and those with lung cancer.
A new study published in JAMA Network Open found that racial and ethnic minorities are more likely to have claims for free preventive care denied by insurance plans, leading to unexpected bills or lack of access. Healthcare providers also charge disadvantaged groups a higher amount for preventive services.
Researchers have discovered an enzyme that degrades polyethylene terephthalate (PET) in sewage sludge, a breakthrough that could help reduce plastic pollution. The enzyme is produced by the bacterium Comamonas testosteroni, which naturally breaks down polymers and can be used to upcycle PET waste.
A study of over 1,329 adults and 1,907 caregivers found that two-thirds of adults with food allergies and three-quarters of adult caregivers reported psychological distress related to food allergy. The biggest barrier to access to psychological help was cost, highlighting the need for free or low-cost support.
Researchers at the University of Copenhagen's Quantum for Life Centre have developed a new mathematical recipe to make quantum simulators more scalable and efficient. This breakthrough could speed up the development of new medicines from years to months by predicting how molecules behave in the human body before laboratory trials.
A new method to construct protein complex-based therapeutics has been discovered using a polymer cloak, which stabilizes the delivery of protein complexes and enables tumor-targeted immunomodulation. The study presents an IL-15 nanosuperagonist with enhanced efficacy and specificity, promising a safer therapy for cancer treatment.
A study found that doxycycline post-exposure prophylaxis (doxy-PEP) did not significantly alter the overall composition of gut bacteria in individuals who took it for six months. However, the researchers noted signs of resistance building against tetracycline, a class of antibiotics to which doxycycline belongs.
The Glenn Foundation Discovery Award supports research into the biological mechanisms of aging, with a focus on developing new treatments. Dr. Jeffrey Friedman and Dr. Myriam Heiman will receive two-year awards to study the cellular basis of hypothalamus aging and charting the cellular rejuvenation landscape in aging neurons.
Researchers estimate that treating hospitalized COVID patients with convalescent plasma saved between 16,476 and 66,296 lives in the US between July 2020 and March 2021. The use of convalescent plasma could have reduced mortality by up to 225% if it had been administered more widely.
Karen Jo Matsler, a UTA professor, is being honored for her extensive contributions to physics education and her efforts to support educators nationwide. Her Quantum for All initiative aims to integrate quantum concepts into high school science instruction, preparing students for careers in quantum technology.
A UTEP study found that zooplankton do not effectively clean feces-contaminated water, contradicting the assumption that they can naturally inactivate pathogen-contaminated waters. The research highlights the limitations of zooplankton as a natural treatment option for polluted bodies of water.
Scientists at Houston Methodist will focus on developing efficacious vaccines and therapeutic antibodies for viruses in the Nairoviridae, Hantaviridae, and Paramyxoviridae families. The goal is to prepare for potential outbreaks and develop effective medical countermeasures in response to a next pandemic.
Researchers at Heriot-Watt University have captured high-resolution images of a five-mile asteroid impact crater buried deep beneath the Atlantic Ocean. The data reveals minute-by-minute chaos after collision, including rocks flowing upwards to the crater floor and an 800-metre-plus high tsunami. The findings confirm the Nadir Crater w...
Researchers review UBA1 loss of function in VEXAS Syndrome, a hematoinflammatory disorder characterized by severe inflammation, cytopenias, and oncogenicity. They explore therapeutic options, including clone-targeting drugs, to combat this challenging disease.
Researchers have discovered that small networks of neurons in the fruit fly's brain can generate an accurate internal compass, contrary to previous assumptions. This finding expands our knowledge of what small networks can do and challenges traditional views on brain size and function.
Researchers develop novel workflows to digitize and future-proof biodiversity data using digital specimen DOIs and nanopublications. This enables scientists to link digital specimens to various databases, facilitating inter-institutional scientific work and saving time for AI systems.
KiNet is an interactive web portal that enables researchers to visualize and study kinase-substrate interactions in systemwide contexts. This facilitates the understanding of kinase functions and their implications in diseases such as cancer, neurodegenerative disorders, and cardiovascular diseases.
Researchers estimate the dollar value of weather information to be over $100 billion, highlighting its significant economic impact. The study also explores lightning suppression and a unique 'storm generator' technology that can create thunderstorms in Chinese desert.
A recent Cochrane review has found that the dental health benefits of adding fluoride to drinking water may be smaller now than before fluoride toothpaste was widely available. The review analyzed data from over 2,900 children in the UK and Australia, estimating a slight reduction in tooth decay, but with significant uncertainty.
A group of scientists and economists warn that green subsidies can have negative spillover effects and diminish overall effectiveness if not implemented cautiously. They suggest imposing time limits on subsidies to ensure they do not perpetuate harmful practices over the long term.
A team of University of Nebraska-Lincoln engineers and scientists are assessing the potential threat to human health from antimicrobial-resistant pathogens spread via wastewater and agricultural runoff. They will use field samples and modeling to determine the contributions from each source and develop a risk assessment tool.
A study published in Environmental Advances found a significant association between four types of PFAS and poor sleep in young adults. The researchers identified genes involved in the body's natural defenses and a hormone that regulates sleep, shedding light on the underlying mechanisms of PFAS' impact on sleep.
A new study by Dr. Kate Goldie Townsend from the University of Exeter highlights the importance of prioritizing children's bodily integrity in protecting them against genital cutting and modification practices. The research emphasizes that children's interest in bodily autonomy should take priority over parental, community, or religiou...
Researchers developed a new method to improve the performance and stability of solar cells using perovskite quantum dots. The
The researchers aim to establish targets for the vaccine by identifying proteins on the surface of early-stage ovarian cancer cells recognized by the immune system. If successful, clinical trials will begin to test the vaccine's effectiveness in preventing ovarian cancer, potentially offering a solution for women at high risk.
Researchers at SWPS University recreated five outfits from the murals of the Faras Cathedral, shedding light on the evolution of royal and clerical attire in medieval Nubia. The study highlights the blend of Byzantine and Muslim influences, as well as the practical considerations of garment construction and dyeing.
Researchers have developed Nucleus++, a new tool for faster and more transparent nuclear data analysis. The software integrates nuclear mass data from the AME and nuclear physics properties from NUBASE, providing enhanced insights for scientists worldwide.
Researchers at the University of Tokyo introduce a new optical computing scheme called diffraction casting, which improves upon existing methods. The system uses light waves to perform logic operations and has shown promise in running complex calculations, including those used in machine learning.
Research reveals European flat oysters formed large reefs of living and dead shells, supporting rich biodiversity and stabilizing shorelines. Historical records show that these reefs existed along Europe's coasts from Norway to the Mediterranean, but were destroyed over a century ago due to overfishing.
Researchers at Houston Methodist are working on a national consortium to develop vaccines against two common and destructive strains of herpesviruses. The project aims to create prophylactic and therapeutic vaccines using a computational toolkit that could transform vaccine development.
The article provides an orientation to using implementation science in policing by integrating effective and evidence-based innovations into routine practices. Researchers offer agendas for integrating IS into EBP, highlighting the importance of metrics to assess police practice outcomes.
Researchers from Michigan State University found that voter purging in the state disproportionately affects lower-income and minority communities. The study suggests that these groups are more likely to be incorrectly identified for removal from voter rolls due to outdated data and inadequate verification processes.
A new study found that over 60% of individuals with moderate and severe menopause symptoms were not receiving treatment, with public insurance being associated with a 47% increase in nontreatment. The primary reason for lack of treatment was clinician recommendation, emphasizing the need for education among healthcare teams.
A recent study found that climate factors play a more dominant role in determining wood density for tree species than soil characteristics, while both factors equally influence shrub species. The research provides new insights into vegetation responses to environmental factors, with implications for improving ecosystem predictions.
Researchers have successfully transplanted human embryonic stem cell-derived retinal organoid sheets into monkeys with macular holes, resulting in graft survival and maturation of light-detecting cells. The study suggests that this method could become a practical treatment option for difficult macular hole cases.
Researchers have developed a peptide inhibitor called RI-AG03 that effectively prevents Tau protein aggregation in lab and fruit fly studies. The breakthrough targets both major aggregation-promoting 'hotspots' of the Tau protein, potentially paving the way for more effective treatments for neurodegenerative diseases.
Researchers at Rutgers University are developing an innovative method called electroponics, which uses electrospray to deliver water and agrichemicals to plants with minimal waste. This technology has the potential to increase food security and sustainability, particularly in water-scarce environments or space stations.
Researchers at Ohio State University have developed a novel method to strengthen polyvinyl chloride (PVC) products by permanently attaching chemical additives using electricity. This new approach can prevent microplastic degradation and improve the material's durability, making it more suitable for various applications.
A novel sensory CBT treatment strategy has demonstrated its potential in a pre-clinical study, improving participants' ability to discard items and reducing anxiety and distress. The study found that imagery rescripting was more effective than other techniques in promoting discarding behavior and reducing negative emotions.
A new study found that increased public attention led to a 22% decrease in fires in the Brazilian Amazon, avoiding approximately 24.8 million tons of CO2 emissions. The heightened scrutiny prompted the government to deploy fire brigades and implement subsequent measures.
Adult childhood cancer survivors experience elevated fear of cancer recurrence, emphasizing the importance of routine screening and timely symptom intervention. The study's findings suggest that fear of cancer recurrence should be a significant concern in survivorship care.
Researchers found that enhancing soundscapes with diverse bird sounds in vineyards improved tourists' experiences, making them feel freer from work and more relaxed. By conserving biodiversity, outdoor businesses can create a positive impact on customers' mental and physical health.