New research suggests that volcanic activity billions of years ago accelerated oxygenation, leading to an increase in atmospheric oxygen. This pre-Great Oxygenation Event (GOE) may have provided the necessary conditions for photosynthetic microorganisms to thrive, ultimately paving the way for complex life.
A new study reveals that firefighters are more likely to have a specific type of brain tumor with gene mutations linked to chemical exposure. The research found that firefighters were more likely to have the mutational signature associated with haloalkane exposure, especially those who worked for many years.
A University of Oxford study found that widely used biodiversity impact assessment tools have significant uncertainties, which can lead to misguided efforts and ineffective strategies if not addressed. The researchers suggest ways to reveal, reduce, and navigate these uncertainties to improve the use of these tools.
A new study has found that sleep debt and night shifts increase the risk of several common infections in nurses. The research, which analyzed data from 1,335 Norwegian nurses, reveals a clear link between slept debt, night work, and infection risk.
Researchers at KIST have developed a high-performance sensor using 2D semiconductors, which overcomes the issues of high resistance and Fermi level pinning. This breakthrough enables the creation of ultra-compact image sensors with exceptional optical properties.
A study found that 70% of eel products in Singapore were mislabeled as European eels, while the endangered American eel was also widely consumed. The research calls for increased monitoring and regulations to prevent overexploitation.
A new study in JSTAT introduces a hiring strategy model that suggests dividing candidates into two groups: those to be evaluated and rejected upfront, and those to be selected based on their performance relative to previous hires. The optimal approach depends on the company's objective, balancing quality and speed.
A new study published in JCOM found that humor can aid scientists' communication efforts, but only if people think they're funny. The research shows that humor can simplify complex concepts, making them more relatable and easier to understand, and has the potential to dispel misinformation in a friendly manner.
A national poll reveals that less than half of parents believe they have accurate information about bird flu. To protect their families, one in three parents have taken action, but some strategies are not evidence-based. The government's response and public confidence in containing the virus also pose concerns.
Researchers used deep learning to predict perovskite solar cell material characteristics and efficiency levels. Machine learning helped identify process errors before finishing, improving data analysis speed and effectiveness.
Researchers used a special measurement technique called M4 resonant inelastic X-ray scattering to analyze the electronic structure and bonding properties of actinide atoms. They found that careful measurement enables a better understanding of actinide atoms' electronic structure and bonding properties.
A new chip-based quantum digital signature network has been developed, significantly improving the signature rate and reducing complexity. The network's star-topology architecture and one-time universal hash-QDS protocol enhance security and performance.
A recent survey of nearly 500 small-scale farmers in Madagascar's northern Sava region found that nearly all are experiencing changes in temperature and rainfall, making farming more difficult. Many farmers are struggling to adapt to these changes and alter their practices despite recognizing the need for change.
The USTC team developed a 105-qubit superconducting quantum processor that achieves a coherence time of 72 μs and outperforms the world's most powerful supercomputer by 15 orders of magnitude. This milestone marks a significant upgrade from its predecessor, Zuchongzhi-2, and demonstrates a record speedup in circuit sampling.
AutoCodeRover, a cutting-edge AI agent platform for software development, has been acquired by Sonar. The technology boosts software engineering and agentic AI innovation, creating new R&D jobs in Singapore.
Researchers from USTC unveil planar optical device that enhances dark-field microscopy capabilities, achieving super-resolution imaging. The compact device uses a scattering layer and metallic film to generate dark-field speckle patterns, enabling high-contrast imaging with improved spatial resolution.
A novel population of bladder-resident macrophages, suPVMs, prevents hematogenous dissemination of uropathogens by releasing macrophage extracellular traps (METs). suPVMs form a bladder-blood immune barrier, preventing bacterial invasion into deeper bladder tissues and facilitating neutrophil infiltration.
A Japanese study found that CGM devices with low-glucose alerts reduced hypoglycemic incidents and increased confidence among diabetic drivers. The findings suggest that such systems can make driving safer for people with diabetes.
A new study found that white blood cells that remember past inflammation events are quick to overreact, raising the risk of blood clots. Researchers discovered that these immune cells, called myeloid cells, have increased blood-clotting activity long after the initial inflammatory event.
A recent study published in Molecular Psychiatry suggests that poor sleep quality among older adults disrupts the brain's glymphatic system, leading to memory decline. The research team found that deactivation of the restorative glymphatic system negatively impacts normal brain function and cognitive health.
Researchers estimate Megalodon's total length at up to 54 feet, with head and tail lengths of 6 and 12 feet, respectively. The study suggests that large body size is not always linked to gigantism, as seen in modern-day sharks like the whale shark.
Researchers used a novel approach to estimate megalodon's body length and shape, finding it closer in shape to a lemon shark or large whale. The study suggests the prehistoric predator may have reached about 80 feet in length and weighed an estimated 94 tons.
A study of nearly 2,500 postmenopausal women found that taking more daily steps and engaging in moderate-to-vigorous physical activity were associated with a significantly reduced risk of death from cardiovascular disease. Even walking fewer than 5,000 steps per day showed a risk reduction.
Researchers have made significant advancements in intracortical neural interfaces for freely moving animals, enabling better understanding of neural circuit functions and mechanisms. These technologies also hold promise for developing more effective therapies for neurological diseases.
Researchers at TIFR Hyderabad have developed a novel porous thin-film approach to enhance reaction efficiency in catalytic reactions. The new methodology integrates a porous heterogeneous thin film in a cross-flow microfluidic setup, allowing for faster reaction rates and increased catalyst reusability.
Researchers develop a novel electron catalysis approach to directly synthesize azo compounds from nitrogen gas, reducing energy consumption and complexity.
Fentanyl poisoning among US children has surged by 924% and 1,506% for teens aged 13-19 over the past eight years. Parents are advised to be vigilant about hidden fentanyl risks and know the signs of overdose symptoms to save their children.
Researchers explore three key directions to address LLM limitations: knowledge empowerment, model collaboration, and co-evolution. Techniques like retrieval-augmented inference and knowledge prompting enhance factual accuracy and interpretability.
Researchers have discovered flows of hot gas in the Centaurus Cluster core, shedding light on how galactic clusters stay hot through 'sloshing' caused by collisions. This solves the longstanding mystery of cluster core heating and provides new insights into the formation and evolution of galactic clusters.
A redesigned Federal Trade Commission (FTC) website has led to a significant increase in consumer reporting of fraud, with complaints jumping by 28%. The new website's improved accessibility and user-friendliness have made it easier for consumers to file complaints, resulting in a greater cross-section of the population participating.
Researchers at USC's Keck School of Medicine discovered that mice display a form of 'first aid' behavior when helping unconscious peers, with actions ranging from gentle grooming to forceful tongue-pulling. This behavior is similar to human emergency responses and may be linked to the activation of oxytocin neuropeptides.
Emerging evidence highlights the significance of circRNA-encoded proteins in various types of cancer, including glioblastoma, breast cancer, and colorectal cancer. These proteins interact with critical signaling pathways, influencing cell proliferation, migration, and apoptosis.
The review article highlights the transformative potential of EZH2 inhibition, paving the way for targeted therapies aimed at disrupting tumor growth. EZH2 inhibitors have demonstrated significant clinical benefits in epithelioid sarcoma and follicular lymphoma, marking an important milestone in epigenetic-based cancer treatments.
The Vanderbilt Lung Transplant program performed a record-breaking 99 lung transplants in 2024, with two combined organ transplants. The program leads the nation in innovation in organ preservation and regeneration, and has the busiest program in the Southeast.
The University of Tennessee has unveiled a new Operator Training Simulator Laboratory in partnership with Kairos Power. The lab will provide hands-on training for reactor operators and serve as a hub for UT students entering the advanced nuclear industry. It features state-of-the-art human-machine interfaces and simulates KP-FHR dynamics.
Recent advancements in gene sequencing identify distinct genetic landscapes for LUAD and LUSC, influencing treatment strategies. Targeted therapies show promise for specific molecular profiles, while immunotherapy outcomes vary between subtypes.
Researchers developed a new approach using metasurfaces to generate multiphoton entanglement, simplifying the process while increasing efficiency. This breakthrough enables the creation of different types of entangled states and facilitates the fusion of multiple pairs into larger groups.
The University of Texas at Arlington hosted the 74th Fort Worth Regional Science and Engineering Fair, attracting more students than ever. The fair featured original research projects on various topics, including using earthworms to remove toxic lead from soil and creating a robotic glove for people with Parkinson's disease.
Researchers assess two approaches to test patients' hereditary cancer risks in primary care clinics, finding the point-of-care approach increases completion rates while the direct patient engagement method boosts testing rates among those eligible. The study's goal is to develop ways to improve uptake and reduce barriers to testing.
The study found disordered kidney metabolism contributes to DM1 symptoms, including muscle weakness and impaired energy use. The kidney is identified as a site of underlying cell dysfunction contributing to the disease.
Coyotes exhibit genetic monogamy, forming long-lasting social attachments. USU neuroscientist Sara Freeman studies the behavioral, hormonal, and neural basis of coyote pair-bonding behavior.
Researchers at Vanderbilt University Medical Center aim to use artificial intelligence technologies to generate antibody therapies against specific antigen targets. The project, funded by $30 million from ARPA-H, will create a massive antibody-antigen atlas and develop AI-based algorithms to engineer antigen-specific antibodies.
A study published in The Lancet Regional Health — Americas highlights growing divide in cardiovascular health in the US, showing that wealth and education play a significant role in heart disease risk. The research reveals that high-income, college-educated Americans face far fewer health risks than the rest of the population.
This review highlights the critical role of ubiquitination in governing cancer stem cell (CSC) functionality, shedding light on potential therapeutic targets. The Ub system regulates key pathways essential for CSC maintenance and survival, particularly through E3 ubiquitin ligases and deubiquitinases.
Research highlights LSD1's pivotal role in regulating cellular processes and human diseases, including cancer, metabolic disorders, and neurological conditions. Inhibitors targeting LSD1 are being explored as potential treatments.
Researchers have developed ExPOSE, a method that allows for the visualization of plant cells with greater resolution, enabling studies on protein and RNA location, and cellular response. The technique uses protoplasts to overcome cell wall challenges, paving the way for a powerful new toolkit in plant biology.
Researchers developed a novel core-shell structured composite to enhance polypropylene's performance at low temperatures. The addition of HDPE improved impact strength and adjusted brittle-ductile transition temperature, while maintaining tensile strength.
A new analysis reveals that nearly half of the genus Heliconia, a group of tropical plants related to birds-of-paradise and bananas, are threatened with extinction. Many imperiled plants are not found within protected areas or botanical gardens, making additional conservation action crucial.
A recent study by the University of Kent found that short animations known as GIFs can improve the sleep of professional female footballers. The researchers designed bespoke GIF messages with sleep hygiene tips and implemented them across a two-week period, leading to significant improvements in sleep quality, even during mid-season.
Researchers at Tohoku University developed a new synthesis method for highly pure porous organic polymers (POPs), eliminating residual impurities and achieving high porosity. The obtained POPs exhibited improved CO2 adsorption capacity, proton conductivity, and unique gas adsorption behavior.
Professor Robert T. Schooley will present a talk at the 8th World Congress on Targeting Phage Therapy, exploring phage therapy advancements and necessary steps for widespread adoption. The congress will gather experts to discuss latest advances, challenges, and clinical applications of bacteriophage therapy.
LearningEMS provides a unified platform for various EV configurations, supporting detailed comparisons of multiple algorithms and benchmarks. The study highlights the strengths and weaknesses of different approaches, emphasizing the importance of state, reward, and action settings in RL-based EMS optimization.
Researchers discovered that aligning protein chains and increasing hydrogen bonds through stretching make spider silk stronger, tougher, and more elastic. The study aims to design engineered silk-inspired proteins for strong, biodegradable materials like sutures and body armor.
Researchers discovered that sulfur bacteria from the Desulfobacteraceae family work together like a team to break down diverse organic compounds. By analyzing six strains, they found similar molecular strategies and a highly energy-efficient central metabolism pathway, enabling them to thrive in oxygen-free environments.
Eradivir's EV25 is a small molecule immunotherapy biotech company developing treatments for influenza. The Phase 2 challenge study will gather safety and efficacy data from healthy participants infected with influenza.
Climate change impacts Arctic coastal ecosystems through melting glaciers, altering kelp growth and elemental composition. Kelps are highly susceptible to changes in run-off intensities, leading to increased metal concentrations and negative ecological consequences.
Researchers investigated the effects of electroacupuncture on gut microbiota and metabolomics in ALS patients, finding a reduction in Eisenbergiella abundance and improvements in Lachnospiraceae levels. The study suggests that this treatment may be beneficial for patients with ALS.
The study reveals a local upward dipole moment at adatom sites on Si(111) surfaces, aligning with experimental results. Variations in atomic arrangements significantly influence charge transfer and dipole moments, providing insights for surface probe microscopy images.
Researchers found a synchronization between geological climate archives and large-scale volcanic eruptions in the Deccan Traps, which may have caused mass extinctions. The study suggests that changes in Earth's orbit around the sun regulate the amount of incoming solar radiation, affecting global climate patterns.
Researchers found that birds of similar age tend to have more similar repertoires, while mixed-age neighbourhoods exhibit higher cultural diversity. The pace of song turnover is driven by individuals coming and going, with older birds serving as 'cultural repositories' of older song types.