As women age, more genes on their X chromosomes escape silencing, potentially influencing disease. This epigenetic change may explain sex-based differences in age-related diseases.
A new study published in Journal of Occupational and Organizational Psychology shows that proactively reorganizing family routines can make people more effective and innovative at work. Employees who take initiative at home carry the momentum into their professional lives, becoming more resilient and forward-thinking.
Researchers found significant brain structure differences between youth with conduct disorder who have been abused and those who haven't. The study's authors believe this may lead to better diagnosis and treatment strategies for children with CD who have experienced childhood maltreatment.
Researchers propose a new method for manipulating light using the geometry of matter, generating second-harmonic signals at much lower intensities than traditional methods. The team's design guidelines offer practical solutions for building nanoscale terahertz devices without applied voltage.
This study investigates the immunomodulatory effects of Ejiao on chronic obstructive pulmonary disease (COPD), focusing on its impact on inflammatory pathways and macrophages. Ejiao significantly improves lung function in COPD model mice, reduces inflammation, and modulates the ER/AKT/NF-κB pathway.
Tandemn, a distributed-GPU network, aims to lower costs and barriers to GPU access while providing owners with possible users for their underutilized resources. The startup secured $1.5 million in funding from private investors after winning the Cozad New Venture Challenge.
In dry conditions, desert locusts produce smaller hatchlings with a 'lunchbox strategy', allocating energy to their first meal for survival. This adaptation allows them to outlast rivals and access more food, giving them an advantage in harsh environments.
The study reveals alarming increases in mental disorders, cardiovascular diseases, smoking, and road injuries across the ASEAN region. Mental disorders affect over 80 million people, while cardiovascular diseases claim 37 million lives, with smoking and road injuries exacerbating the problem.
This novel treatment approach yields better weight loss maintenance and cardiovascular risk outcomes compared to standard-of-care treatment. Patient-delivered lifestyle intervention combined with peer support significantly improves weight loss and reduces cardiovascular risk.
BYU researchers found that sugar from beverages like soda and fruit juice is consistently linked to a higher risk of developing type 2 diabetes. In contrast, dietary sugars from whole fruits, dairy products, or whole grains do not cause metabolic overload in the liver.
Researchers at the University of Stirling have identified fibroblast-like stem cells in the skin of Atlantic salmon, which play a central role in wound healing and tissue remodeling. These adult stem cells are thought to be involved in maintaining the skin's barrier and structural properties.
Researchers developed a new computer modeling approach to simulate the behavior of tiny nanoparticles in the air, improving accuracy and efficiency. This could lead to better monitoring of air pollution and more precise ways of predicting its effects on human health.
The study analyzed the causal impact of digital infrastructure on debt costs using China's 'BroadBand China' policy. Key findings show that digital infrastructure increases corporate debt costs, highlighting its dual significance for businesses and policymakers.
This review highlights the promise of traditional South Asian medicinal plants in addressing memory loss and cognitive decline, particularly in Alzheimer's disease. The identified plants not only reflect cultural wisdom but are increasingly supported by modern scientific evidence.
Changes to a pest's diet could delay the evolution of resistance to biopesticides, according to University of Stirling scientists. The study found that altering the crop a pest eats has a greater impact on resistance than switching pesticide types.
Researchers have uncovered evidence of humans using whale bones as tools from 20,000 years ago, shedding light on the marine ecology of the time and the role whales played in past ecosystems. The study identifies five species of large whales used by early humans.
Researchers model how human behavior, in response to disease risk information, creates waves of infection. This model helps explain recurrent patterns seen in real-world epidemics by incorporating social and operational factors.
A new study found that oral microbiome diversity is positively associated with long sleep duration among teenagers and young adults. This association suggests a potential relationship between the oral microbiome and sleep health during adolescence, an essential developmental period.
A recent study found that rural location and racial segregation significantly impact primary care access in Virginia, with nearly half of the state's census tracts lacking adequate physicians within a 30-minute drive. Racial segregation and rurality were strongly associated with reduced access to primary care physicians.
A Japanese study found that choosing the right type of meal can extend meal duration and encourage more mindful eating. Researchers discovered that traditional bento-style meals with individual components promoted longer meal times and more chewing compared to fast food.
Researchers identify five distinct immunotypes in tongue squamous cell carcinoma, shedding light on why current immunotherapies fail. The study's findings highlight the need for immune-based assessments to guide treatment decisions and suggest a new approach to personalized medicine.
A new microfluidic device promises to revolutionize kidney disease screening by enabling rapid, accurate, and low-cost testing of creatinine levels in urine. The uCR-Chip delivers clinically relevant results within 7 minutes and meets the sensitivity standards of existing point-of-care tests.
Researchers have developed a new approach to regularize the theory of critical phenomena by generalizing statistical mechanics. The new method, based on non-additive entropy, provides finite values for quantities that diverge in traditional theories, offering insights into complex systems.
These next-generation contact lenses analyze tear fluid, track intraocular pressure, and release medications without requiring external power or invasive procedures. They offer a promising solution for continuous, noninvasive health monitoring and have the potential to transform ophthalmic care.
Researchers found that women tend to use the ocean closer to shore than men, with implications for equitable marine planning and governance. This study highlights the importance of considering gender-based differences in marine spatial planning efforts.
Researchers developed binary phase-engraved (BiPE) superpixel CFM to overcome limitations of existing technology, enabling high-speed and high-efficiency complex field modulation. BiPE superpixels can utilize all incident light components, increasing optical efficiency.
Researchers analyzed trends in healthcare utilization among Japan's oldest-old population aged 75 years and above during the extended COVID-19 pandemic. The analysis revealed a modest drop in medical services and outpatient visits, while healthcare costs remained stable despite decreased patient volumes.
A new study shows that lowering EMC10 levels restores brain function and memory in models of 22q11.2 Deletion Syndrome. Reducing EMC10 activity also alleviates symptoms, including improved cognitive deficits and social memory performance.
A study reveals an increasing polarisation between Asia and Western nations in future battery technologies, with Europe and the US focusing on improving existing lithium-ion batteries. Meanwhile, countries like China, Japan, and South Korea are investing in high-energy batteries and low-cost alternatives.
Researchers mapped TB cases in Africa using a Bayesian geospatial analysis, revealing dramatic differences in disease burden between local regions. The study's findings highlight the importance of targeted health resources and could help reduce tuberculosis deaths by 95% by 2035.
A study by University of Cologne researchers reveals that parenthood is associated with a greater sense of meaning in life, despite lower life satisfaction. The analysis of over 43,000 participants from 30 countries found that people who have children tend to feel their lives carry more value and worth.
Scientists have created the first soft robots that can walk out of the machines that make them using a new 3D printing system. The flexible devices were developed to overcome challenges in manufacturing and design, making them suitable for various industries like nuclear decommissioning and space exploration.
Dr. Roni Porat joins the CIFAR Azrieli Global Scholars program to research reducing prejudice and fostering coexistence between Jewish and Arab communities. She will receive CAD $100,000 in funding and access to CIFAR's global network.
A new co-optimization framework for MEMS devices combines genetic algorithms with freeform geometry modeling, enhancing performance and robustness. The approach improved sensitivity by 195% in a MEMS accelerometer, demonstrating its potential for next-generation sensors across industries.
The European Vaccines Hub for Pandemic Readiness (EVH) is a pan-European center that integrates excellence in vaccine research, human monoclonal antibody development, clinical trials, and scalable manufacturing. EVH aims to drive innovation and ensure strategic autonomy in vaccine R&D and manufacturing.
The ERQA framework uses a semantic vector database and curated literature repository to improve medical knowledge discovery, achieving high retrieval accuracy in literature-based QA and abstract summarization. The researchers plan to further improve the model by incorporating larger-scale biomedical literature datasets.
The study found that almost half of researchers have experienced the Gollum effect, with two-thirds reporting repeated encounters. The phenomenon undermines scientific progress and disproportionately affects early-career and less established researchers.
Researchers from The University of Osaka have demonstrated that vision transformers can spontaneously develop human-like visual attention patterns without specific training. This breakthrough showcases the potential of self-supervised learning for advancing AI applications and modeling biological vision.
The F3T sensor accurately decouples temperature, normal force, and all-directional tangent force. It outperforms traditional sensors in static and dynamic tests, enabling robots to adaptively respond to external disturbances.
Researchers discovered that EGFR plays an active role in KRAS-mutated colon cancer, despite previous assumptions. The study found that blocking EGFR can slow down sugar metabolism and activate a gene signature associated with longer survival in patients with KRAS mutations.
A new guideline aims to improve hypertension management in Canada, focusing on practical recommendations for primary care providers. The guideline uses WHO's technical package as a framework, addressing discrepancies in blood pressure targets and guideline complexity.
Researchers developed an energy-efficient measurement system leveraging waveform similarity to achieve high precision with minimal power consumption. The system demonstrated 72μW power efficiency using commercially available electronic components, paving the way for long-term bio-signal monitoring and self-powered IoT devices.
Researchers have developed bioactive dressings with on-demand regulation to address the complexities of diabetic wound management. These dressings target specific factors such as glucose levels, inflammation, and infection, promoting healing and reducing recurrence rates.
Researchers discovered a novel connection between the amygdala brain region and social learning in zebra finches. Young birds preferred approaching tutors with longer but less frequent songs, suggesting the amygdala plays a role in socially selective behavior. This finding sheds new light on the neural mechanisms underlying song learning.
Research by sociologist Sara Wiertsema found that young adults tend to exercise less after starting their first job. However, an activating social and work environment can help them maintain physical activity levels. Young people are more likely to continue exercising if they receive social support from colleagues or friends.
A study found that dog owners are willing to pay a premium for foods labeled with specific health attributes, such as digestive health and allergy care. The most expensive attribute was 'allergy relief,' with an average price of $3.89 per pound.
The article proposes four indicators for targeted policies: investment type, local availability of skilled workers and materials, information and advice, and split incentives. It recommends pilot projects to facilitate the transition and make better use of existing data sources.
Researchers at Tohoku University developed jellyfish cyborgs that harness the organism's natural swimming style, predicting movement in any direction using a lightweight AI model. The findings demonstrate the potential for soft-bodied marine animals to inspire innovations in robotics and climate research
The study evaluated the mutation profiles of lung squamous cell carcinoma (LSCC) detected by next-generation sequencing to assess relationships with clinicopathological parameters. Detection of mutations revealed associations between certain genes, such as PIK3CA and NF1, with specific histopathological features.
Insilico Medicine is launching a pilot project in the UAE to discover a novel drug candidate for oncology therapeutics using its proprietary Pharma.AI platform. The project aims to accelerate traditional drug discovery timelines and leverage local talent to create world-class therapeutics.
A survey of stakeholders in Japan found that incorporating patient voices into assessments of genetic conditions can recalibrate people's ideas about seriousness, shifting perceptions from a tool of societal burden reduction to individual reproductive autonomy. The study emphasizes the need for including patient voices in shaping ethic...
The team developed a demonstrator to optimize water treatment plant operation through full-scale tests at CIRTESU. The system simulates processes, measures water velocity and turbulence, and analyzes mixing effects.
A new study from UC San Diego School of Medicine reports no clinical differences in core autism traits between female and male autistic children aged 12-48 months. The researchers found sex differences in typically developing females, but not in autistic children.
The university successfully secured funding for two new clusters, SCALE and CPI, which will focus on understanding cellular architecture and cardiovascular diseases. The clusters aim to pioneer new paths in medicine through innovative research.
Researchers identified five adenosine phosphate signaling subtypes in melanoma, associated with immune activation and improved response to anti-PD-1/PD-L1 therapy. The Adenosine Phosphate Signaling Model predicts prognosis and immunotherapy outcomes, offering new biomarker and therapeutic strategies for solid tumors.
Researchers at TROPOS found new product channels in isoprene's oxidative degradation, which could influence atmospheric aerosol growth and secondary organic matter formation. The study suggests that highly oxidised isoprene peroxy radicals are formed globally every year, potentially playing a significant role in these processes.
A new study found that climate change is driving sexual and reproductive health risks among young adolescents in Kenya, with food, water, and sanitation insecurities linked to school dropout, gender-based violence, and early pregnancy.
Carbyne, a linear chain of carbon atoms, exhibits unexpected quantum mechanical interactions with surrounding nanotubes. This phenomenon is due to the intrinsic electronic properties and structural instability of the chain, making it strongly react to external influences.
A recent study published in Engineering delves into the complex mechanisms of multiphase reactive flow during CO₂ storage in sandstone. The research team identified significant changes in petrophysical properties, including pore and throat sizes, due to chemical reactions.
The African Union's new policy brief proposes implementing the IDAWM framework to address agricultural water management challenges in Africa. This will involve balancing environmental, social, health, and governance trade-offs to create resilient agri-food systems that deliver multiple benefits for people and the planet.