A new UC lab-on-a-chip device developed by engineers measures the stress hormone cortisol from a patient's saliva, helping doctors diagnose depression and anxiety. The device provides objective evidence for clinicians to supplement traditional screenings, raising red flags about patients' levels of stress.
A multidisciplinary team analyzed seismic waveforms to reveal a significant low shear-wave velocity anomaly at a depth of 5.4–8 km, indicating possible liquid water in the upper crust.
Researchers have discovered that mature liver cells transform into immature states and divide rapidly in response to damaged tissue, a process similar to what occurs in human patients with drug-induced liver injury. This understanding could lead to more effective treatments for liver failure by targeting the regenerative program.
Researchers have identified a unique genetic signature in T cell clones that predicts treatment success, enabling personalized immunotherapy approaches. The study's findings also suggest that activating specific T cell clones within the tumor can enhance immune response and improve treatment outcomes.
A study by the University of Exeter and Fishtek Marine found that illuminated pots caught significantly more northern shrimp and attracted fish, raising hopes for sustainable fisheries. The 'attraction cascade' creates a self-baiting pot, potentially leading to new low-impact trap fisheries.
A new report highlights the drastic decline of endangered primate species worldwide, emphasizing the urgent need for global conservation efforts. Habitat destruction, hunting, climate change, and illegal wildlife trade are major threats to these animals.
Researchers have developed an enhanced Digital Light Processing (DLP) 3D printing technology that can create composite magnetic structures with different materials in one step. The new method, introduced by Tsinghua University scientists, presents extensive potential for designing and manufacturing multifunctional soft robots.
A study by Aalto University researchers found that people's perception of AI creativity increases with the amount of process and producer information revealed. This discovery has implications for designing creative AI systems, as well as understanding human biases towards creativity in others.
Researchers at MD Anderson Cancer Center have made breakthroughs in understanding pancreatic cancer metastases and identifying potential biomarkers for treatment-resistant pancreatic cancer. A comprehensive spatial map provides insights into lineage shifts in cancer cells transitioning from primary tumors to organ-specific metastases.
Reginald DesRoches, Rice University President, has been elected to the 2025 class of ASCE distinguished members for his groundbreaking research in earthquake engineering and disaster resilience. He is recognized for his leadership and mentorship in improving engineering education.
A study published in Cell describes a powerful AI tool that can design synthetic molecules to control gene expression in specific types of cells. The model creates DNA regulatory sequences not seen before in nature, allowing for ultra-selective switches to be turned on or off in healthy mammalian cells.
Researchers at Pohang University of Science & Technology (POSTECH) have developed an achromatic metagrating that handles all colors in a single glass layer, eliminating the need for multiple layers. This breakthrough enables vivid full-color images using a 500-µm-thick single-layer waveguide.
The TUCAN6-CM project aims to transform next-generation mobile networks through efficient integration of communication, computing, and sensing technologies. Advanced solutions will enhance quality of life, sustainability, and safety in smart cities and industrial environments.
A new study from the University of Helsinki unravels the causes of ancient climate changes that led to severe droughts in North America thousands of years ago. Researchers used fossil pollen grains and machine learning algorithms to reconstruct moisture levels, confirming that conditions were below modern levels for thousands of years.
A new study in Bangladesh finds that simple and inexpensive interventions can cut emissions by up to 10% and boost profits for producers. The findings offer a scalable model for tackling pollution in hard-to-regulate informal industries, particularly in low- and middle-income countries.
A comprehensive analysis of cancer statistics found that incidence rates of 14 cancer types increased among people under age 50. Researchers speculate that risk factors such as obesity and changes in cancer screening may contribute to these increases.
Researchers at Washington University in St. Louis have made strides in removing selenium contamination from water using iron electrocoagulation, a process that generates iron-containing solids with large surface areas to bind selenium. The method removed more than 98% of selenium by flowing through an iron reactor for 11 seconds and se...
Researchers present an intelligent solution to manage complex energy systems, improving frequency stability and reducing settling time by up to 283% compared to traditional controllers. The innovative FO-Fuzzy PSS controller incorporates a specialized washout filter, ensuring smooth operation even during turbulent conditions.
Researchers at State University of Campinas found that physical exercise prevents the transition from acute to chronic muscle pain by activating an anti-inflammatory signaling pathway in immune cells. This can lead to the development of new treatments for muscle pain, potentially reducing opioid consumption.
A new study by Reichman University and Copenhagen Business School found that companies reducing international operations by 10% or more can subsequently expand at a faster rate than those that didn't. These companies invested freed-up resources into new initiatives, such as patent applications, indicating growth in innovation capacity.
A new Vanderbilt University Medical Center-led study found US veterans with depression had a 14% higher risk of heart failure, even after adjusting for traditional risk factors. The study suggests that screening and treating depression may help prevent future heart failure in patients.
Researchers developed MuSICCA, a music therapy tool that uses musical stimulation to assess levels of consciousness in children with brain injuries. The study found high agreement among participants that the tool is suitable for use with children, providing guidance for caregivers and supporting clinical teams.
The study found increasing incidence rates for five cancer types without corresponding increases in late-onset age groups. The greatest increases were seen in female breast cancer, colorectal cancer, kidney cancer, and uterine cancer.
Researchers at the University of Würzburg have developed a new, efficient method for recording gene activity in bacteria. The MATQ-seq protocol achieves a high cell retention rate of 95% and detects the activity of 300 to 600 genes per bacterial cell.
Researchers at Umeå University and Michigan State University have found a type of molecule that can kill chlamydia bacteria without harming human cells or beneficial bacteria. This breakthrough discovery opens the door for developing new antibiotics against chlamydia, the world's most common bacterial sexually transmitted disease.
A study found that microRNA-27a promotes dental tissue regeneration by suppressing inflammation and activating Wnt/BMP signaling pathways. The researchers used human dental pulp stem cells to overexpress miRNA-27a, which led to the formation of new bone-like tissue in mice.
A new analysis reveals that the Çöpler Gold Mine site had been slowly moving for at least four years prior to the fatal landslide, highlighting the need for continuous monitoring. The study suggests integrating infrastructure management with monitoring and rapid response mechanisms to avoid future disasters.
A new study from the Keck School of Medicine of USC found that children born to mothers with obesity, gestational diabetes, and hypertensive disorders have higher systolic and diastolic blood pressure. The study's findings suggest that early blood pressure interventions could start as early as pregnancy.
A new study found that brick kiln owners in Bangladesh are willing to implement energy-efficient operational changes after receiving training and support. The changes led to a 23% reduction in energy use and substantial savings in coal expenditures.
The MARUM-QUEST 5000 successfully tested its system and took samples during a dive at the Menez Gwen hydrothermal field at 830 meters. The new ROV replaces the MARUM-QUEST 4000 and offers improved payload capacity, control technology, and gripper arms for deep-sea observations.
A new study by UCLA researchers shows that advanced MRI imaging and targeted focal therapy can help many men with low- to intermediate-risk prostate cancer safely stay on active surveillance long-term, avoiding follow-up biopsies and delaying or avoiding invasive treatments. The findings suggest that routine follow-up biopsy can now be...
Researchers have developed a safe and natural solution to boost crop resilience and recover yields in citrus and potatoes. The new approach uses spinach antimicrobial peptides, which naturally defend plants against pathogens, showing promising results in recovering yield and improving quality in diseased plants.
A new study from Uppsala University investigates how sleep deprivation affects biomarkers associated with cardiovascular disease. Researchers found that chronic lack of sleep increases the risk of heart problems by promoting inflammatory proteins.
A new NIH study found that maternal cardiometabolic health before and during pregnancy is associated with higher blood pressure in children. The study analyzed data from 12,480 mother-child pairs and identified three key risk factors: pre-pregnancy obesity, gestational diabetes, and high blood pressure during pregnancy.
A cohort study of 12,480 mother-offspring pairs found that pre-pregnancy obesity, gestational diabetes, and hypertensive disorders of pregnancy are associated with increased offspring blood pressure. These risk factors may also promote a faster rate of blood pressure change from age 2 to 18 years.
Researchers developed soft robots that use airflow and simple design to move efficiently without centralized control. The robots' self-oscillating limbs can perform rapid stepping motions and adapt to environmental changes.
Researchers developed a rapid fluorochromic sensing method for detecting tertiary amines and opioids, enabling faster and more accurate analysis. The new approach uses photoinduced charge-transfer complexes to differentiate between structurally similar amines based on their substituents and molecular flexibility.
Scientists have identified a promising target for new drugs to combat tropical diseases such as Chagas and leishmaniasis. The discovery was made by studying the pathogen that causes African sleeping sickness, Trypanosoma brucei, and its unique organelles, glycosomes.
A new AI model, EVE-Vax, uses evolutionary data to predict viral proteins and design future-proof vaccines against rapidly mutating viruses like SARS-CoV-2. By analyzing millions of years of genetic information, the model can create brand-new proteins with the same immune response as real viruses.
A study found that exercise improves the maturation of transplanted stem cells and their integration with host neurons in a rodent model of Parkinson's disease. This enhancement is attributed to increased secretion of beneficial proteins in exercising rats, promoting transplant survival and function.
A recent study found that a protein called URI degrades p53, leading to uncontrolled cell proliferation and tumour formation. Researchers have identified URI as a crucial regulator of p53 levels, which may be associated with environmental factors such as poor diet.
Durham University scientists have reclassified a 500-million-year-old fossil as a distant relative of sponge-like creatures, chancelloriids. The reclassification reveals that the fossil's features were not indicative of molluscan biology, but rather preservation artefacts of the fossilisation process.
A new study reveals that a gene typically used for detoxifying smelly compounds has evolved to produce unpleasant odors in flowers. This unique reaction involves the transformation of methanethiol into dimethyl disulfide, a key feature of foul-smelling flowers.
A recent study by UFZ reveals that PFAS influence the cellular immune response to SARS-CoV-2, particularly in males. The researchers found that high PFAS exposure alters the immune response, potentially reducing its effectiveness and increasing the risk of poor disease progression.
A new study reveals how a promising Parkinson's drug works by inhibiting the enzyme USP30, which prevents damaged mitochondria from being degraded. This breakthrough could lead to targeted therapies for Parkinson's disease and chronic kidney disease.
A cohort study of US veterans found that depression is associated with a higher hazard of incident heart failure after controlling for demographic and cardiovascular risk factors. Depression remains consistent as a risk factor even in low-risk cohorts.
Researchers at MIT created a table tennis bot that can return shots with high-speed precision, achieving a hit rate of 88% in tests. The technology could be adapted to improve the speed and responsiveness of humanoid robots for search-and-rescue operations.
A recent study found that narcissistic individuals tend to prefer negative gossip, while those who are not narcissistic may be uncomfortable with either positive or negative gossip. Gossip can serve social functions when done with good intentions and without lies.
Researchers found that atmospheric mercury levels have decreased significantly due to reduced human-caused emissions, mainly attributed to the Minamata Convention. The study also revealed that soil emissions now make up a larger fraction of total mercury emissions, with re-emissions from soil posing a future challenge.
Researchers found that silencing Mitch, a key regulator of mitochondrial fusion, increases cellular respiration and burns more fats and carbohydrates. In human cells, deleting Mitch leads to increased muscular endurance and a decrease in fat accumulation.
Researchers used virtual reality to test how incarcerated burglars evaluated a neighborhood with houses differing in features. The study found that offenders adjusted their perceptions of risk and reward based on the environment. Environmental features like street lighting and housing design influenced the men's likelihood of breaking in.
Researchers found that supplements of B vitamins B6, B9, and B12, as well as choline, slowed down damage to the optic nerve in glaucoma. This was observed in experiments on mice and rats with glaucoma, where eye pressure was left untreated.
Scientists from the NA61/SHINE experiment have observed a clear anomaly indicative of a violation of flavor symmetry between up and down quarks. The study used argon and scandium atomic nuclei and reported an overproduction of charged kaons, contradicting theoretical predictions.
Recent advancements in compensation circuits have achieved impressive results in addressing key inefficiencies in wireless EV charging. Researchers refined converter topologies to deliver high-power, high-efficiency charging without physical connectors, demonstrating improved power transfer.
The FAU CARD water safety manual provides crucial guidance on preventing wandering, identifying potential drowning risks, and implementing prevention strategies. The manual aims to reduce the risk of drowning among children with autism by empowering parents and caregivers with knowledge and tools.
APHA Executive Director Yvette Raphael received the Mani L. Bhaumik Breakthrough of the Year Award for her pivotal role in developing and testing Lenacapavir, a breakthrough HIV prevention method. Her commitment to community-centred research has transformed global health and inspired collaboration across disciplines.
Physicist Matthias Schott is developing a dedicated neutrino detector for the LHC that can handle high data transfer rates, enabling researchers to study high-energy neutrinos. The detector uses GridPix technology and may reveal new insights into neutrino interactions, including potential evidence of anti-tau neutrinos.
A cross-sectional study found common experiences of gaslighting and substantial distress among patients with vulvovaginal disorders. The study emphasizes the need for education supporting a biopsychosocial approach to vulvovaginal pain, as well as the development of validated instruments to quantify patient experiences.
A new breakthrough in photopharmacology has been achieved with the design of a wireless capable of remotely activating a photoactivable drug. The device demonstrates efficacy in treating pain and opens up new perspectives for designing safer and more effective analgesic treatments.
The SEMACRET project developed socially and environmentally sustainable means of exploring critical raw materials in the EU. Research results refined ore deposit models, optimizing regional prospectivity modeling and advanced geophysical imaging inversion algorithms.