Researchers have identified a distinct population of neuroprotective microglia that may point to a new therapeutic approach for Alzheimer's disease. Microglia with reduced expression of PU.1 and co-expression of CD28 limit neuroinflammation and slow amyloid plaque build-up.
Researchers at Columbia University School of Engineering and Applied Science have discovered that a thin-film metallic resistor used to thermally tune photonic devices can also measure temperature. This finding may help integrated photonics reach its full potential by eliminating the need for bulky external temperature sensors.
Scientists have discovered a new species of deep-sea limpet clinging to a sunken log in the Central Pacific Ocean. The discovery provides crucial insights into ocean biodiversity and ecosystem secrets, revealing that even tiny islands of habitat can sustain deep-sea communities long enough for population turnover and dispersal.
Irrigation expansion has increased water losses from land through evapotranspiration, depleting freshwater resources in hot spot areas. In regions like South Asia, climate change and irrigation exacerbate humid-heat stress risks.
The Mount Sinai Health System will implement Microsoft Dragon Copilot, an AI-powered voice assistant designed to streamline clinical documentation and automate administrative tasks. The rollout aims to reduce burnout, improve patient experiences, and enhance clinical efficiency across the system.
A study has identified a key molecular mechanism that prevents the loss of brown adipose tissue activity during ageing. By targeting chaperone-mediated autophagy, researchers have found effective ways to boost metabolic energy expenditure and prevent obesity-related diseases.
A study published in Neurology found a significant link between heart attacks and the development of late-onset epilepsy in older adults. Researchers discovered that people who experienced a heart attack were nearly twice as likely to develop late-onset epilepsy, with a higher risk of dying from vascular causes related to the brain.
A groundbreaking environmental DNA test developed by Florida International University scientist Diego Cardeñosa can detect traces of elusive hammerhead sharks in water samples. The test reveals fragments of genetic material left behind in the ocean, identifying areas where the sharks have been and informing conservation efforts.
A new study from the Hebrew University of Jerusalem reveals that while Israel can technically sustain itself through local vegetative food production, the economic price would be staggering. The researchers argue that a balanced approach, combining agricultural innovation, diversified import sources, and strategic food storage, offers ...
Researchers analyzed data from Solar Orbiter's PHI and EUI instruments to study the Sun's supergranulation and magnetic network at the south pole. The findings show that the magnetic field drifts towards the poles faster than expected, providing important clues about the Sun's global plasma and magnetic field circulation.
Seagrass meadows, such as Posidonia, accumulate around 1.5 tonnes of carbon per hectare in the living parts of plants and fix nearly 7 tonnes each year. The global assessment confirms that these ecosystems play a key role in absorbing atmospheric CO₂, transforming it, and retaining it.
Researchers at NUS have developed ultra-thin memtransistor arrays from 2D TMDC materials with controllable Schottky barriers, achieving high performance for image recognition tasks. The arrays demonstrate low device-to-device variation and high uniformity.
Binghamton University scientists have developed a novel bioelectronics material that combines living liquid metal with electrogens to create next-generation devices. This innovation has the potential to revolutionize fields such as biomedical sensing and device integration.
A new international study confirms that drug-coated balloons can effectively treat larger narrowed blood vessels, offering a safer alternative to stents. The findings validate the method developed by Professor Bruno Scheller and demonstrate its efficacy in treating arteries with diameters larger than 2.75 mm.
A study by Johns Hopkins Medicine researchers found that preterm infants admitted to the neonatal intensive care unit (NICU) are at a higher risk of developing persistent hypertension as they grow. The study suggests that NICU admission itself may contribute to the increased risk, and highlights the need for early hypertension screenin...
A new study found that prepopulating e-commerce search bars with trending or personalized keywords increases purchase incidence by 10.4% and overall spending by 8.8%. The research also reveals that these design choices shape the entire online shopping journey, from query to checkout.
A new study reveals a connection between parents' attachment styles and the likelihood of experiencing parental burnout. The research suggests that difficulty in recognizing and understanding one's own emotions can increase the risk of burnout.
The University of Houston has been redesignated by the NSA as a Center for Academic Excellence in Cyber Research (CAE-R) through 2029. This recognition underscores UH's growing role in advancing research and workforce training to strengthen US resilience against evolving cyber threats.
Research found a strong link between living in deprived areas and poorer cognitive performance, with damage to brain small blood vessels and modifiable lifestyle factors contributing to the effect. Lifestyle habits such as exercise and sleep management also play a crucial role in dementia prevention.
A study by McGill University found that nerve injuries can lead to widespread inflammation in the body, differing between male and female mice. The research suggests that long-term immune system changes may increase the risk of chronic diseases such as chronic pain, anxiety, and depression.
A new study found that central adiposity, measured by waist-to-hip ratio, is a risk factor for domain-specific cognitive decline in postmenopausal women. The study suggests that measures of central adiposity may serve as early and easily recognizable markers of risk for both metabolic and cognitive dysfunction.
Researchers created a multidimensional molecular map of brain development after birth and its response to inflammation, finding that some developmental programmes can be reactivated during neuroinflammation. This study provides new clues for understanding how myelin is broken down in diseases like MS.
Researchers at OIST develop a new method harnessing 'jumping genes' to recreate the termite tree of life, providing a template for solving ancient evolutionary mysteries. The study achieves similar accuracy to trees built from thousands of protein marker sequence alignments.
Researchers track benthic nutrient fluxes using a new device called CAROSEL, which measures nitrogen released from sediments in real-time. The findings reveal daily rhythms in oxygen fluxes and highlight the importance of understanding sediment-water interactions in managing aquatic ecosystems.
Kono recognized for his contributions to optical physics, light-condensed matter interactions and photonic applications of nanosystems. His research explores how light interacts with materials at the nanoscale, potentially leading to new technologies in electronics and quantum communication.
The increasing use of unregulated psilocybin mushrooms poses a pressing need for public education, potency testing, and age-specific risk assessment. Existing clinical data are insufficient to guide harm reduction or policy, highlighting the need for real-world research on psilocybin use.
A new study found that individuals with narcissistic rivalry tendencies are more likely to damage team dynamics, leading to lower cohesion and poorer performance. In contrast, narcissistic admiration didn't seem to impact performance, but those individuals were increasingly viewed as less hardworking and arrogant by their teammates.
Researchers discover tiny antibody-like proteins from camels and llamas that can treat brain disorders like schizophrenia and Alzheimer’s disease with fewer side effects. The nanobodies are smaller than conventional antibodies, making them easier to produce and purify.
Scientists discovered that eIF1A and eIF5B suppress toxic protein synthesis implicated in frontotemporal dementia and amyotrophic lateral sclerosis. The study sheds light on the mechanisms behind RAN translation, a process linked to neurodegenerative disorders.
A new brain atlas developed by UCL researchers enables analysis of brain scans at an unprecedented level of detail, opening up possibilities for studying neurodegenerative diseases and ageing. The atlas uses AI to identify hundreds of brain regions in living patients quickly and consistently.
A nationwide study found that involuntary psychiatric patients have a significantly higher risk of suicide, particularly during the first month after discharge. The risk is elevated for several years and is associated with factors such as age, diagnosis, and previous self-harm.
The superior colliculus, an ancestral brain structure, enables the brain to distinguish objects from the background and detect relevant stimuli in space. It generates centre–surround interactions independently, allowing for the detection of contrasts, edges, and salient features.
A new study published in the Chinese Neurosurgical Journal explores an AI tool that identifies medulloblastoma subgroups based on magnetic resonance imaging scans. The model achieved impressive accuracy in predicting molecular subtypes and genetic risk factors, with 91% accuracy for TP53 mutations and 87% accuracy for chromosome 11 loss.
A new study has found that the Southern Ocean releases substantially more carbon dioxide during the dark austral winter than previously thought. The findings suggest that the region plays a more complex and dynamic role in the global carbon cycle, with implications for climate models.
Researchers discovered a threefold reduction in harm among patients with coronary artery stenosis who experience pulmonary embolism. Patients with CAS had lower signs of right ventricular strain, including heart rate and biomarker levels.
A team of scientists at the University of Seville identified a key process protecting DNA integrity in reproductive cells, preventing genetic defects during egg formation. The study found that phosphorylation acts as a 'switch' against DNA damage, allowing the genome to repair itself properly during meiosis.
A new case report describes the successful treatment of a 37-year-old woman with HER2-positive breast cancer that had spread to the membranes surrounding the brain and spinal cord. Trastuzumab deruxtecan, an antibody-drug conjugate, improved the patient's neurological symptoms and reduced cancer growth.
Researchers discovered that blocking a specific protein called ferroptosis suppressor protein 1 (FSP1) reduces tumor growth by up to 80% in mice with lung adenocarcinoma. This study provides hope for developing novel clinical therapies for cancer patients.
The WCSJ 2025 conference aims to combat misinformation and fake news, a critical challenge undermining science communication and public health. The event will feature expert discussions on innovative ways journalists are tackling misinformation and highlight the need for fact-checking and informed societies.
Researchers found that fungal species from warmer sites in Baltimore had lighter pigmentation and greater heat resistance compared to cooler sites. This study suggests that urban fungi may be adapting to higher temperatures, potentially leading to new disease-causing pathogens like Candida auris.
Researchers have created detailed maps of the mammalian brain's developmental stages, shedding light on how brain cells form and mature. The findings provide valuable insights into the critical periods that may help diagnose and treat neurodevelopmental disorders such as autism and ADHD.
Research from Michigan Medicine uncovers connections between a longevity gene, behavior, and environment, suggesting that manipulating stress responses could extend life without downsides. Touch activates a circuit modulating signals to reduce the longevity effect of dietary restriction.
Researchers identified a PU.1-promoting subset of microglia that suppresses inflammation and protects cognitive function in mice with Alzheimer's disease. This discovery opens a new avenue for immunotherapies targeting microglial activity.
A breakthrough study from Aarhus University identified two amino acid changes that allow plants to switch off their immune system and form symbiosis with nitrogen-fixing bacteria. This discovery could lead to breeding crops like wheat, barley, and maize that can fix nitrogen themselves, reducing the need for artificial fertilizer.
Researchers can utilize a combination of automated and manual actions to quickly identify suspicious behavior and prevent fraudulent actors from enrolling in online studies. A comprehensive checklist of indicators helps researchers spot potential fraud, such as similar patterns in email addresses or predictable responses.
Researchers developed a points-based classification model using eight variables to assess joint pain, genetic mutations, and iron loading. The criteria show promise in diagnosing haemochromatosis arthropathy with high specificity and sensitivity, paving the way for new treatment options.
A study published in Communications Biology reveals that certain p53 mutants can hijack the DNA replication machinery, leading to aggressive cell proliferation and triggering a strong immune response. This discovery could lead to personalized cancer treatment strategies by identifying tumors with mutant p53 variants like R273H.
The University of the Witwatersrand has launched the Earth Observatory and CORES, aiming to drive innovation in the minerals sector. The observatory provides cutting-edge geoanalytical techniques, while CORES integrates economic geology, extractive processes, and data-driven innovation to promote sustainable mining practices.
Researchers found somatoform disorders impact 4.6% globally, with 662 years of life lost per 100,000 people due to these conditions. The study highlights the need for increased resource allocation and awareness about these often-diagnosed-incorrectly disorders.
A new NIH grant will support the development of stronger and healthier parent-child relationships among parents in recovery, critical for sustained recovery and positive child development. The project aims to empower peer recovery specialists with tools to deliver meaningful parenting support alongside recovery services.
Research at the University of Helsinki reveals that forest thinning can temporarily boost carbon storage in upland forests, while drained peatlands become stronger net carbon sources due to slower tree growth and increased decomposition. The study highlights the importance of adapting management practices to different forest types.
A study found that certain biomarkers in blood are associated with symptom severity during recovery from concussion in adolescents, with significant differences between male and female patients. Higher levels of tau protein were found in female patients, while lower levels were linked to increased physical symptoms in males.
Researchers found that pairs who worked together on a jigsaw puzzle displayed greater movement synchronization on trampolines than those who worked individually. Initial rapport also had a positive effect on movement synchrony. The study provides new insights into how cooperative interactions enhance interpersonal synchronization.
A new study from the University of Eastern Finland found that bark beetle damage clusters in Finland tend to concentrate in groups near previous infestations and mature stands. The research analyzed forestry land data and identified forest characteristics increasing the likelihood of a stand becoming part of a cluster.
An international team led by University of Arizona archaeologists has discovered a large ritual construction, Aguada Fénix, dating back to 1,000 B.C. The monument measures nearly a mile long and features a cross-shaped pit with ceremonial artifacts, including jade axes and pigments associated with cardinal directions.
Researchers at OIST develop world-class 'hurricane-in-a-lab' setup to study turbulent Taylor-Couette flows. By re-examining Kolmogorov's framework, they find that the power law predicts universal behavior across all small-scale flows, resolving a long-standing inconsistency.
A nationally representative survey found that frequent parent-teen communication is associated with increased teen self-efficacy for sexual and reproductive health information. Teens whose parents feel comfortable discussing topics are more likely to seek services, highlighting the importance of accurate information and open dialogue.
Scientists at Scripps Research have identified a key player in placental development - galectin-3, which binds to sugar molecules on cell surface proteins, facilitating cell fusion. The study provides new fundamental insight into placental biology and could lead to preventing or treating pregnancy complications.
A new study found that heavy alcohol use is associated with more severe brain bleeds and long-term brain vessel damage at a younger age. Patients who drank three or more drinks a day had larger, deeper bleeds and were twice as likely to have damage in the tiny blood vessels in the brain.
Research reveals that strong winds transport phosphorus to the ocean's surface, benefiting cyanobacteria that convert atmospheric nitrogen into a form usable by Sargassum algae. This symbiotic relationship gives Sargassum a competitive advantage in the Equatorial Atlantic and explains past changes in biomass.