The review highlights perilipin 2's role in regulating hepatic lipid metabolism and its implications in various liver diseases, including hepatitis B, C, and alcoholic liver disease. PLIN2 acts as a biomarker for diagnosis and prognosis, while also influencing treatment response and tumor susceptibility.
Researchers at the University of Würzburg developed a new type of organic light-emitting diode that enables the creation of miniature displays. The pixel is made up of an optical antenna, a metallic contact, and a specially manufactured insulation layer, allowing for efficient current injection and amplification.
At the 2025 Fortune Global Forum, Insilico Medicine's CEO Dr. Alex Zhavoronkov will share his vision for a future where generative AI can help humanity live better and longer. The company has advanced its AI algorithm development and built industry collaborations across the Middle East.
Developed a novel EEG transformer model, Augmenting Electroencephalogram Transformer (AETF), to enhance steady-state visually evoked potential-based brain–computer interface (BCI) systems. The AETF model improves decoding efficiency by capturing temporal, spatial, and frequency features of dynamic EEG signals.
A novel approach to ecological security planning integrates ecological connectivity, climate-specific risks, and economic feasibility to ensure climate-resilient ecosystems. The study highlights the importance of maintaining forest integrity and ecological connectivity to preserve ecosystem services and biodiversity.
The book highlights the risk of 'scope creep' and emphasizes the need for strong data protection frameworks to preserve trust. It argues that collaboration between humanitarian actors, academics, regulators, and affected populations is crucial to ensure technology serves humanity.
Researchers engineered a new strain of Metarhizium fungus that mimics flower scents to attract and kill mosquitoes. The floral-scented fungus is harmless to humans and breaks down naturally, making it a promising alternative to chemical pesticides.
New research shows that near-term mitigation could spare future generations around 0.6 meters of sea-level rise caused by emissions between 2020 and 2090 following current policies. The study provides a direct link between today's policy choices and sea levels hundreds of years from now.
Scientists have discovered small-scale torsional Alfvén waves in the Sun's corona, which are magnetic disturbances that can carry energy through plasma. These waves could power the Sun's outer atmosphere, reaching temperatures of millions of degrees.
A new study using next-generation imaging technology discovered that when the brain is falling asleep, it shows a coordinated shift in activity. Areas involved in thinking, memory, and daydreaming quiet down and use less energy during NREM sleep.
Researchers found a genetic variant that protects against winter vomiting disease, which was introduced to Europe through early farmers around 6,000 BCE. The FUT2 gene variant is linked to an increased risk of stomach ulcers and gallstones, but provides full protection against the virus.
Australian researchers have discovered that common nervous system components, neuropeptides and their receptors, drive tumour growth in gastrointestinal cancers. Drugs targeting these components, already used to treat migraines, may be repurposed as cancer treatments, providing promising new avenues for treatment.
A food tax shift could reduce premature deaths and disease by 700 annually and 700,000 tonnes of carbon dioxide emissions in Sweden. The study shows that selective taxes on unhealthy foods can lead to healthier diets without increasing the average price of groceries.
A USC Dornsife study found that combining two types of brain scans improves predictions of future anxiety in teens, shedding light on how the adolescent brain responds to mistakes and identifying at-risk youth sooner. The research may eventually lead to earlier, more personalized mental health interventions.
Researchers developed an organocatalytic method to create planar chiral cyclophanes with high stereoselectivity and diastereoselectivity. The method uses a chiral phosphoric acid catalyst and generates a reactive naphthoquinone methylene intermediate, leading to the formation of stable planar chiral type III cyclophanes.
Researchers at the University of Adelaide discovered a gene responsible for a rare form of wheat that grows three ovaries per flower. The study found that a complex genome rearrangement was associated with the activation of a normally dormant WUSCHEL-D1 gene, leading to increased grain production and improved breeding technologies.
A study reveals that nucleoside supplementation speed up DNA replication by a specific balancing act involving T (thymidine), which counteracts an inhibitory molecule, dUTP. Adding T increases the correct molecule, dTTP, preventing dUTP from interfering with DNA synthesis.
A new study led by Silent Spring Institute examines how job-related chemical exposures contribute to breast cancer risk among foreign-born workers. Immigrant women are overrepresented in high-risk jobs with fewer health and safety protections, facing unique barriers to avoiding toxic exposures at work.
Researchers develop AI-powered methods for modeling the Gulf of Mexico's dynamics, achieving higher accuracy for short-term predictions and emulating 10-year dynamics without hallucinations. This breakthrough drives forward critical management of natural resources in the U.S. and Mexico, advancing AI technology in earth sciences.
A study published in Tobacco Control found that teenagers and young adults who use cannabis are more likely to become regular tobacco users, even if they haven't previously tried tobacco. The study estimated that 13% of new regular tobacco use is attributable to cannabis, with significant implications for tobacco control programs.
Researchers have developed novel nanomaterials to combat myocardial ischemia-reperfusion injury, demonstrating significant cardioprotective effects in preclinical models. These nanoplatforms improve drug enrichment efficiency and reduce systemic toxicity, showing considerable clinical translation prospects.
Researchers used boron isotope fingerprinting to track the release of boron from two glass compositions. The findings show that the formation of a protective altered layer controls long-term contaminant release, with magnesium-driven secondary mineral precipitation enhancing dissolution rates.
Researchers developed a robust Ni-Fe spinel catalyst for efficient hydrogen generation at lower temperatures, demonstrating strong activity and resistance to carbon deposition. The optimized catalyst achieved high methane conversion rates and hydrogen concentrations at temperatures as low as 650 °C.
Native halophytic plants reduce alkalinity and promote mineral weathering, organic matter accumulation, and organo-mineral interactions to initiate early-stage soil formation in alkaline bauxite residue. This approach creates a low-input rehabilitation strategy for vast bauxite disposal sites worldwide.
Researchers at the University of Technology Sydney discovered that tailored lipid supplements can significantly increase coral larvae's strength, speed, and survival rate. This innovation has major implications for reef restoration projects, which aim to improve larval supply but often face low post-settlement survival rates.
The Baltic states of Lithuania and Estonia topped the Index on International Media Freedom Support, while Latvia came in 9th. The report highlights a significant gap between public commitments and actual support for media freedom among larger countries like the US, UK, Italy, and Japan.
A US study found that teenagers who use cannabis are more likely to become regular tobacco users, with 32.7% of those aged 12-17 progressing to regular tobacco use four years later. The study estimates that around 13% of new regular tobacco use is attributable to cannabis.
A novel therapeutic candidate has been developed to treat severe cutaneous adverse reactions such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). The compound suppresses disease-specific keratinocyte death, demonstrating its efficacy in preclinical studies.
Researchers developed a dual-breakthrough method to recycle phosphorus from sewage sludge into smart fertilizers, enhancing soil health or rapid crop growth. The innovative approach utilizes modified hydrochar with calcium or magnesium salts, controlling phosphorus release and improving its bioavailability.
A trio of biomedical scientists defend DEI programs, citing data that shows broader participation leads to more effective training environments, greater novelty, and higher impact research. They warn against scaling back DEI programs, which would stall scientific progress and threaten a multi-dimensional democracy.
Dr. Bethany Slater, a highly skilled and compassionate surgeon, has been appointed as Division Chief of Pediatric Surgery at Mount Sinai Kravis Children's Hospital. She will focus on advancing surgical excellence, expanding minimally invasive techniques, and enhancing multidisciplinary care for children and families.
A study from University of Utah Health found that combining psilocybin group therapy with mindfulness training significantly reduced depression in healthcare workers. Nearly half of participants experienced complete remission of depression after just two weeks.
The American Heart Association and American Academy of Pediatrics have published updated guidelines for cardiopulmonary resuscitation and emergency cardiovascular care for newborns and pediatric populations. The new guidelines provide specific recommendations that reflect the unique needs of children, emphasizing the importance of trai...
A new review highlights how exogenous phytohormones can strengthen sugarcane's ability to cope with both drought and waterlogging. Emerging technologies like robotic systems and nanotechnology are being developed to deliver hormones precisely when and where they are needed.
Researchers found that carefully managed applications of woody biochar significantly improved soil quality, crop yield, and carbon balance in red pepper fields. Optimal biochar application levels ranged from 7 to 11 metric tons per hectare when crop residues were removed after harvest.
The BRIGHT Center aims to equip researchers with state-of-the-art tools to expand the impact and reach of trauma interventions. The center's goal is to make a difference in the lives of those affected by trauma in South Carolina and across the nation, building resilience after trauma.
A $5 million grant from the Steven & Alexandra Cohen Foundation will support The Menopause Society's NextGen Now initiative, creating a comprehensive digital ecosystem for menopause education and training worldwide. The initiative aims to improve healthcare professionals' care for midlife women and enhance their knowledge of menopause.
A blood test detecting tiny fragments of cancer DNA can help tailor chemotherapy to individual patients with stage 3 colon cancer. The DYNAMIC-III study found that patients with low-risk levels had an 87% cancer-free rate three years after surgery, while those with high-risk levels had a much higher risk of recurrence.
A research team has found that vital RNA needed to maintain telomeres in roundworms exists inside another gene's intron. This discovery suggests a common strategy for anti-aging therapies and regenerative medicine in humans, and could support species survival.
Genos, an open-source Human-Centric genomic foundation model, has been released to transform medicine and health research. The model achieves strong performance on ultra-long inputs, enabling the prediction of individual disease risks and the interpretation of pathogenic mutations with high accuracy.
A new study from UC San Francisco found that saturated fat affects the behavior of a protein called PER2, which orchestrates fat metabolism and circadian rhythms. Mice eating a diet high in hydrogenated fats struggled to adapt to winter, whereas those on unsaturated fat diets adjusted easily.
A recent study from Harvard John A. Paulson School of Engineering and Applied Sciences uses wearable sensor technology and machine learning to estimate ground-reaction forces in runners. This data can provide insights into performance and injury, enabling the development of devices that deliver real-time feedback to users.
Researchers have created a molecule that strongly binds to the nanocrystal's surface, slowing down energy leaks and extending the charge separation time. This technique enables more efficient use of light-driven chemical reactions.
Rabbi Lior Nevo has received the Heart and Hands Award from LeadingAge Massachusetts for her spiritual leadership and personal counsel. Her work supporting Jack Satter House's Spectacular Seniors 2025 Calendar was also celebrated for its joyful, stereotype-shattering innovation.
Researchers at Stanford University have identified a common crystal that can efficiently convert low-energy photons into high-quality entangled photon pairs. The discovery has significant implications for the development of highly sensitive and stable quantum sensors.
A new study shows that Neanderthals and Mesolithic hunter-gatherers had a significant impact on vegetation patterns in Europe, with human-induced fires and hunting affecting up to 47% of plant type distribution. The research challenges the notion of an 'untouched landscape' in Europe before agriculture.
International experts have established guidelines for gene therapy in hereditary hearing loss, emphasizing patient-centered care and respect for diversity. The guidelines outline frameworks for clinical trials, including patient selection criteria, surgical procedures, and safety evaluations.
Researchers developed a time-resolved cryo-ET method to capture snapshots of cultured neuronal synapses. The study identified a 'kiss-shrink-run' pathway that unifies the debated 'kiss-and-run' and 'full-collapse' fusion mechanisms, providing a structural basis for efficient synaptic transmission.
Researchers have developed magic cube metamaterials that can dynamically control electromagnetic fields, overcoming limitations of traditional materials. The technology has potential applications in human-machine interaction and electronic devices.
A new chip architecture has successfully overcome major limitations of photonic neural networks, achieving record-breaking input sizes and robust performance with partially coherent light sources. The device demonstrated accuracies of 94% and 96% in handwritten digit and fashion image classification tasks.
The Association for Molecular Pathology recognized Dr. Laposata's contributions to clinical laboratory practice and his role in challenging the FDA's rule on laboratory-developed test regulation. The award preserves diagnostic innovation, ensures patient access, and avoids escalating healthcare costs.
Carol and John Fountain's $236 million gift will help sustain University Hospitals' community-focused mission. The South Pavilion at UH Ahuja Medical Center will be named in their honor, recognizing their transformative support.
A UH crystals expert has shown how to bend and twist crystals without physical force, using a molecule called a tautomer. This discovery has potential applications in drug delivery and material properties, such as optoelectronics and soft robotics.
A massive exoplanet dubbed 'super-Earth' has been discovered orbiting a nearby dwarf star, offering new hope in the hunt for other worlds that could harbor life. The exoplanet, GJ 251 c, is approximately four times as massive as Earth and likely to be rocky.
A new study from Karolinska Institutet found that countries with higher human development indices and lower gender inequality have higher levels of cardiorespiratory fitness among young adults. Women's VO2peak was significantly higher in countries with high gender equality compared to those with low gender equality.
A Norwegian study of over 21,000 adolescents and young adults found that those with persistent parental opioid prescriptions faced more than double the risk of persistent opioid use. The study suggests considering family-based approaches to managing pain conditions in adolescents and young adults.
Japanese Catholic universities' nursing faculties emphasize core values like loving all people, wholeness, and resilience, which shape patient care. These values are actively embedded in education and align with Catholic social doctrine.
The 15th annual Les Turner Symposium on ALS will bring together leading researchers to discuss the latest research and perspectives on the disease. Dr. Don Cleveland, a renowned expert, will deliver a keynote address on developing designer DNA drug therapy for neurodegenerative diseases.
New research reveals that textile color, particularly dark dyes, significantly accelerates microfiber release and degradation. This study provides crucial insights into the ecological risks of synthetic microfibers and highlights the need for stricter monitoring and pollution control strategies.
Researchers from Princeton University uncover the origins of the human-biting mosquito Culex pipiens molestus, dating it back over 1,000 years to ancient agricultural societies in Egypt. The study reveals genetic links between bird-biting and human-biting mosquitoes, crucial for understanding West Nile virus transmission.