A new study reveals that a specific E. coli strain can block the gut's defense mechanism by injecting a protein called NleL, allowing it to spread more easily. This discovery could lead to new treatments that target how bacteria cause disease.
Under climate change scenarios, backyard birders in South Africa can still appreciate diverse bird species, but declining biodiversity and climate change may reduce birding opportunities in protected public parks. The study found that cultural ecosystem services, like birding, have non-market value and are essential to human well-being.
A new study published in PLOS One found that nearly one-third of adults with type 2 diabetes in India achieved remission through a comprehensive mobile-based program combining diet, exercise, stress management, and medical support. The program showed significant improvements in weight, body mass index, glycated hemoglobin levels, fasti...
Researchers develop food-safe, natural film using edible fungus that blocks water, oil and grease absorption on various materials. The film, grown on common materials such as paper, denim and polyester felt, reveals its potential to replace single-use plastics with sustainable, natural materials.
A new Northwestern University study reveals that abnormal cells in transplanted lungs engage in harmful 'conversations' with the immune system, leading to damage and rejection. The findings provide a comprehensive roadmap for treating chronic lung allograft dysfunction and other scarring lung diseases.
A novel machine learning framework combines interpretable deep learning with multiscale computational techniques to predict lattice thermal conductivity. The approach identifies high-performance materials for thermal management and energy conversion, providing deeper insights into heat transfer at the atomic scale.
Fungi are older than previously imagined, with origins dating back to between 900 million and 1.4 billion years ago. The discovery sheds new light on pre-Cambrian terrestrial ecosystems, suggesting that fungi were already present on land environments at least 800 million years ago.
A rare case of pancreatic Hodgkin lymphoma was reported, emphasizing the need for tissue diagnosis before definitive treatment. The patient's symptoms and imaging findings initially raised concern for pancreatic adenocarcinoma, but a biopsy revealed nodular sclerosis subtype of Hodgkin lymphoma.
A new technique allows researchers to track the distribution of chemotherapy drugs within cancer cells, enabling more accurate determination of treatment effectiveness. This breakthrough could pave the way for personalized cancer therapies.
Black and Asian patients were underrepresented in clinical trials, leading to worse survival outcomes compared to white counterparts, despite similar progression-free survival rates. Equitable enrollment is crucial for access to cutting-edge treatments and long-term equity in cancer care.
A study by MIT researchers found that design elements of data visualizations influence viewers' assumptions about the source of the information and its trustworthiness. Readers make these assessments primarily from design features like color palette or arrangement, rather than underlying data, often unintentionally by designers.
Japanese physicists have shown that knots can arise in a realistic particle physics framework, potentially explaining the origin of the universe's matter surplus. By combining two long-studied extensions of the Standard Model, the team found a stable knot configuration that could have formed and dominated in the early universe.
Researchers at Corewell Health aim to create the world's first algorithm to design personalized treatment plans for individual patients using dynamic SPArc therapy. This technology could reduce treatment time from 30 minutes to just five and improve access to high-quality cancer care.
A study published in Neurology Open Access found that people with both gum disease and cavities have a higher risk of ischemic stroke. Researchers analyzed data from 5,986 adults and found that those with both conditions had an 86% higher risk of stroke compared to those with healthy mouths.
Researchers developed a computational tool to identify genetic vulnerabilities in memory-making brain cells linked to Alzheimer's. The 'seismic' algorithm integrates genetic data with single-cell RNA sequencing, revealing a detailed picture of affected cell types and their genetic programs.
Scientists have discovered olivine-bearing clasts from a lunar regolith sample, shedding light on the migration of Carbonaceous Ivuna-type chondrites to the Earth-Moon System. The findings provide new insights into the origin of water on the lunar surface.
Idiopathic hypersomnia is a rare condition characterized by excessive daytime sleepiness. Patients report never feeling rested or awake despite adequate sleep, affecting their daily lives. The study analyzed online posts to better understand the experience and impact of living with this disease.
Scientists studied the crystalline waste of over 20 reptile species and found spheres of uric acid in all of them. This unique packaging method may inform treatments for human conditions like kidney stones and gout.
A new study by researchers from ETH Zurich, University of Erlangen-Nuremberg and Research Institute for Sustainability found that European citizens prefer solar power and decentralized energy systems over lower costs. The study suggests that incorporating social data into energy modeling can lead to more realistic and socially acceptab...
Researchers at University of Würzburg discover carpenter ants perform prophylactic amputations on injured workers, halving infection spread and doubling survival rate. This unique approach is reminiscent of human medical logic, highlighting the importance of timely treatment in densely populated colonies.
The study reveals key cargo clients and accessory factors mediating AP-1 and AP-4-dependent cargo proteins in the secretory pathway, providing insights into their physiological and pathological roles. Novel cargos such as CAB45 and ATRAP are identified, highlighting the importance of vesicle proteomics in dissecting molecular mechanisms.
UofL Health – Brown Cancer Center oncologists and researchers will continue developing novel therapies using patients' own immune system to defeat cancer. The center's faculty and research facilities support clinical trials that bring new treatments to patients.
Researchers found that when cooled and confined together in a tiny space, photons sort themselves into the state with more occupants. This trend could help design ultra-powerful lasers by exploiting the particles' tendency to conform.
The game, developed in partnership with Polk County Emergency Management, will force players to grapple with uncertainty and trade-offs in their actions. It aims to add intensity and engagement to traditional training methods, allowing emergency responders to make timely and relevant decisions.
Boston University researcher Brian Cleary has been awarded a five-year, $2.25 million NIH grant to investigate how gene expression changes over time in single cells. His project aims to develop new computational-experimental approaches to track RNA velocity vector fields and deepen understanding of cell physiology.
Researchers explore ZBP1-mediated programmed cell death, its mechanisms, and therapeutic strategies for systemic diseases. The review also discusses ZBP1's involvement in various types of cell death, including apoptosis, necroptosis, pyroptosis, and ferroptosis.
Researchers developed an ingestible capsule inspired by firefly bioluminescence to diagnose acute mesenteric ischemia, a potentially deadly but often underdiagnosed condition. The capsule generates light after activation by the small intestine's pH, which is transmitted wirelessly to diagnose the condition with 90% accuracy.
A new study by UC San Diego found that a third of Californians use cannabis regularly, yet there are significant gaps in knowledge about driving-related laws and regulations. The researchers emphasize the need for targeted education initiatives to address these knowledge gaps and promote safe driving practices.
Researchers investigated the role of PLAGL1 in postnatal condyle development and found that it regulates osteogenesis through the IGF2 pathway. The study reveals a critical driver of jaw bone formation, offering opportunities for therapeutic exploration and a deeper understanding of craniofacial biology.
The termination of thousands of federal grants has raised ethical concerns about clinical trial closures, particularly among children and adolescents. Researchers argue that sudden stops can break trust and harm participants, violating long-standing principles.
Researchers at Boston College have identified a novel bacterium that can thrive on spent battery waste, producing protons capable of leaching electrode materials. The bacteria, Acidithiobacillus ferrooxidans, also shows promise in recycling Li-Ion battery cathode materials using iron and stainless steel as food sources.
A recent study has found an association between gum disease and changes in the brain's white matter, which can affect memory, thinking, balance, and coordination. Adults with gum disease had more white matter hyperintensities, a type of damage that can increase stroke risk.
Researchers developed a non-destructive tool for evaluating loblolly pine disease resistance, achieving 81.5% training accuracy and 68.7% testing accuracy with NIR spectroscopy. The study demonstrates the potential of vibrational spectroscopy to transform forestry phenotyping and precision forestry.
Sugarcane intercropping improves soil health by breaking up compacted soil, enhancing nutrient use, and promoting microbial diversity. Practical cases in southern China show expanded applications with legumes, maize, vegetables, and green manure crops, improving land use efficiency and organic matter content.
Researchers have published a comprehensive review on additive manufacturing for nanogenerators, offering critical insights into the transformation of energy harvesters through 3D printing. The review highlights key findings on innovative designs, applications, and future outlooks, while addressing current limitations and challenges.
Research at the Amazon Conservatory for Tropical Studies found that arboreal mammals, such as sloths and monkeys, use canopy bridges in the Peruvian Amazon to cross over treeless areas. The study provides insights into how forest creatures adapt to human-made structures.
The study reveals that the Israeli Mediterranean Sea fosters extraordinary nutritional and health properties in seaweeds, with high protein content and antioxidant levels during winter and spring respectively. These findings highlight seaweed as a natural source of health-promoting compounds and potential therapeutic agents.
China's farmland exhibits a dual characteristic of strong emissions and weak carbon sink, but optimizing management can reduce emissions by 11.6 Tg CO2-eq per year. Implementing '4R nutrient management' and improved irrigation techniques can increase soil organic carbon content and enhance carbon sequestration capacity.
Researchers from Shenzhen University review cement-based thermoelectric materials for their potential in smart construction, energy harvesting, and structural monitoring. The study highlights key challenges and proposes future directions for the development of these materials.
Jillian C. Shipherd, a professor of psychiatry at Boston University School of Medicine, has received the 2025 Charles Silverstein Lifetime Achievement Award in Social Justice for her significant contributions to advancing social justice initiatives, particularly in LGBTQ+ health policy and research. Her work focuses on the intersection...
A randomized clinical trial found that repeated ketamine infusions provided no additional benefit to standard care for inpatients with serious depression. The study, led by Declan McLoughlin and Ana Jelovac, highlights the need for recalibrated expectations in clinical practice and underscores the importance of blinding in trials.
A research team has taken a major step forward in spintronics by discovering dual torque from electron spins driving magnetic domain wall displacement. This breakthrough could lead to the development of high-speed, energy-efficient memory chips using artificial antiferromagnetic materials.
A new method to recycle PA-66, a type of polymer found in fishing nets and automotive parts, has been developed. The process involves introducing melamine into melted waste, resulting in a nylon material with improved properties that can be reprocessed up to three times.
Neutrino experiments from US and Japan have combined their data to measure precise neutrino behavior, bringing scientists closer to understanding how matter was favored over antimatter in the early universe. The results shed light on neutrino oscillation, a phenomenon that could help solve the missing antimatter problem.
A large-scale cohort study found that stopping drinking even at low levels can lead to clinically meaningful reductions in blood pressure. Researchers analyzed data from over 359,000 adults and discovered that quantity of alcohol intake is the primary driver of blood pressure changes.
Researchers at Helmholtz Centre for Infection Research have identified a new drug candidate, Substance 31, that prevents the production of new proteins in malaria parasites. This approach has the potential to break through existing resistances and develop new therapeutic strategies against malaria infections.
A new study has compiled records of brain activity during sleep and dream reports, revealing that dreams occur not only during REM sleep but also during deeper and calmer NREM stages. In these cases, brain activity resembles wakefulness more than deep sleep.
A new national study suggests that strengthening screening programs at community-based federally qualified health centers (FQHCs) could significantly increase cervical cancer screening rates and ultimately save thousands of lives. Currently, only about 55% of women seen at FQHCs are up to date on cervical cancer screening, far below th...
The American Thoracic Society's new Clinical Practice Guideline provides evidence-based recommendations for tracheostomy care in children. The guideline emphasizes the importance of applying ethical principles and involving caregivers in decision-making, with a focus on ensuring high-quality, family-centered care.
Researchers recreated chemical reactions from 4 billion years ago, producing formic acid and acetic acid without enzymes. These findings support the hypothesis that underwater hydrothermal vents played a key role in the emergence of life.
The 2025 Cmolik–SFU Grant Program awards $150,000 to BC public schools for innovative tech-based STEAM projects. The program aims to build critical thinking skills and foster curiosity among students from kindergarten to Grade 12.
Researchers from Chalmers University of Technology have developed a technology with the smallest pixels ever, allowing for screens with the highest resolution possible for human eye perception. The breakthrough enables the creation of virtual worlds visually indistinguishable from reality.
Research found that high-fat and high-carbohydrate diets are controlled by separate neural pathways in the brain. Neuropeptide Y neurons activate AMPK-regulated corticotropin-releasing hormone neurons to promote high-carb intake, while inhibiting melanocortin 4 receptor neurons to increase high-fat intake.
A team of researchers developed a battery-free wearable patch that measures bioimpedance to detect skin lesions, distinguishing between healthy and abnormal skin. The patch's effectiveness was tested on 10 volunteers, showing significant differences between healthy and suspicious moles.
Ants have evolved a unique transcriptional mechanism to ensure one scent receptor is active per neuron, preventing societal collapse. This 'bulldozer' system silences all neighboring genes when one gene is chosen by chance, promoting precise control of olfactory receptors.
Renato D.C. Monteiro has made fundamental contributions to theory in operations research and the management sciences, reshaping optimization and advancing complexity analysis. His work has stood the test of time, impacting fields such as machine learning, control systems, and statistical modeling.
The UC San Diego REACH Center for Translational Science on Whole Person Health aims to advance research through partnerships with complementary and integrative health institutions. The center will support at least 26 new research scholars and fund pilot grants to drive innovation in translational science.
Eleven researchers have earned the Advanced Science Young Innovator Award for their outstanding and innovative work in materials science, physics, chemistry, medical and life sciences, and engineering. The award recognizes scientists whose research is bridging fields and accelerating practical applications.
Scientists have replicated the neural circuitry that allows zebrafish to react to visual stimuli and maintain their position in flowing water. The research, published in Science Robotics, used simulations and robots to study embodiment, or how the body affects perception, in larval zebrafish.
Researchers at Cincinnati Children's propose a unified approach to understand blood cell formation, identifying rare cell populations and gene regulatory networks. This breakthrough advances targeted therapies and stem cell engineering.