A medieval individual buried in the Menga dolmen in Andalusia has been found to have a mixed ancestry, with uniparental lineages typical of European populations and mitochondrial DNA shared with modern North African individuals. The study sheds light on the genetic diversity of Andalusian society during the Middle Ages.
MicroEnsemble wins AI Weather Quest, demonstrating improved sub-seasonal weather forecasting accuracy. The team uses AI technologies to post-process state-of-the-art forecasts, achieving consistent performance across various weather variables.
GSI/FAIR's new Galactic Cosmic Ray simulator enables researchers to better understand radiation doses and control effects in human tissue and technical components. The simulator replicates the GCR exposure in a lightly shielded habitat, providing a crucial tool for space radiation research.
Recent discoveries have shed light on gene expression control in tumor growth, revealing the critical role of epigenetic marks and genomic imprinting. The findings have significant implications for cancer treatment, as they suggest that disrupting the tumor's access to neural signaling may halt its growth.
Researchers found that fedratinib inhibits BRD4, activating a transcriptional pathway that induces ERMCS formation and causes structural changes in organelles. The study provides a potential therapeutic avenue for diseases like neurodegeneration, obesity, and cancer.
A new study suggests that exercise can improve mental sharpness and reduce cognitive decline in cancer patients undergoing chemotherapy. Researchers found that patients who exercised while on chemotherapy maintained their daily step goals and reported improved mental clarity, while those who did not exercise experienced significant dec...
Researchers explored using CDK4/6 inhibitors to treat PDAC by targeting RB1, which is often inactivated by oncogenic KRAS. This approach showed promise in inducing cellular senescence, but further combination therapy is needed for therapeutic benefit.
Researchers discovered that intrinsically disordered regions (IDRs) retain function through interplay of linear motifs and chemical characteristics, not just conserved sequence blueprints. The study found that short binding motifs and overall chemical context are crucial for protein function.
Researchers have identified and resolved molecular bottlenecks to produce doxorubicin, a vital chemotherapy agent, resulting in a 180% increase in production. This breakthrough enables cost-effective manufacturing of essential antibiotics and anti-cancer agents, promising a cleaner and more reliable supply of life-saving medicines.
A novel design strategy has been proposed to efficiently synthesize methanol from CO2, decoupling active sites through a strong metal-support interaction. This approach enables a significant increase in methanol yield compared to conventional catalysts.
Researchers at Brown University develop a way for robots to use inputs from both human language and gesture to reason about object location. The approach, which incorporates insights from dog behavior, achieved an 89% success rate in finding the correct object in complex environments, outperforming other methods.
Researchers found that D, L-buthionine-(S, R)-sulfoximine (BSO) replicates the anti-obesity effects of sulfur amino acid restriction without causing bone loss in male mice. The study suggests BSO as a promising tool for dissecting the beneficial versus deleterious axes of sulfur amino acid biology.
Researchers at Tohoku University have developed a comprehensive digital materials ecosystem that integrates AI tools to streamline materials design, enabling faster and more accurate discovery of new materials. The ecosystem uses databases, AI, and scientific workflows to predict material properties and optimize design processes.
The study investigates ocean-atmosphere variability under Miocene-like high-CO2 conditions to evaluate climate-model performance in warm climates. ENSO variability peaked under 3×CO2 and was damped under 4×CO2, with El Niño events exhibiting longer mean duration than La Niña events.
Researchers engineer T cells to express specific TCRs, demonstrating that antigen recognition drives phagocytosis and identifying key regulatory parameters, such as antigen density. The study's findings offer mechanistic insights and translational promise for immunotherapy.
A study led by Dr. Edward Ricemeyer reveals that the Amazon molly maintains its genome through gene conversion, which helps remove harmful mutations and allows natural selection to keep working in the absence of recombination. This process empowers natural selection in a clonal fish species, maintaining overall genome integrity.
Scientists have developed a novel 2D multiferroic metal, bilayer CrTe2, with intrinsic room-temperature multiferroicity and strong magnetoelectric coupling. The material exhibits reversible out-of-plane polarization and demonstrates 'electrical writing and magnetic reading' capabilities.
A new photocatalyst design using machine learning interatomic potential calculations has successfully identified suitable dopants for a novel tin oxide material. The resulting aluminum-doped material produces 16 times more hydrogen under visible light than the undoped material, paving the way for next-generation clean energy applications.
Researchers from Institute of Science Tokyo created a system that turns spoken impressions into personalized makeup colors, combining AI and projection technology. The system shows realistic makeup previews on real skin under natural light, making it easier for users to find suitable colors.
Moons around free-floating planets can keep their water oceans liquid for up to 4.3 billion years due to dense hydrogen atmospheres and tidal heating. This allows for stable habitats for complex life to develop and could significantly broaden the spectrum of possible environments that could harbor life.
Researchers found penicillin-streptomycin increases macrophage stiffness and rewires ECM mechanosensing, impairing immune function and suggesting potential off-target effects in clinical use. The study highlights the need to re-evaluate common cell culture reagents through a mechanobiological lens.
Researchers at Kyoto University discovered that bees favor flowers with early visitors over color, even when the latter has an initial disadvantage. This finding indicates that social information plays a crucial role in pollinator choice, and flowers that secure early visitors may gain a lasting advantage.
Researchers investigated temperature-dependent sex determination in leopard geckos, finding that temperature influences sex development during a specific window of embryonic development. Early genetic changes, including the activation of male and female developmental pathways, occur before physical differences become apparent.
A Chinese study reports a 100% technical and clinical success rate for robot-assisted brain angiography, with median procedure times 11 minutes shorter than manual angiography. No added radiation or complications were observed, showcasing the feasibility and safety of the YDHB-NS01 system
Researchers have discovered a new chemical reaction that can be used to modify anti-tumor compounds, produce recyclable plastics, and develop new materials. The 'trisulfide metathesis reaction' is a clean, efficient method that can be completed within seconds.
A study by the Institute of Environmental Science and Technology of the Universitat Autònoma de Barcelona establishes the principles for modelling post-growth scenarios, pointing to the need for targeted demand-side measures and investments in low-carbon technologies. The research highlights the potential for post-growth to achieve pos...
Researchers developed predictive AI models that identified patients at risk of intimate partner violence from their medical records, years before they enrolled in care. The models achieved high accuracy and could detect IPV up to four years before patients sought care.
A study by Florida Atlantic University researchers has uncovered the impact of stress on wild songbirds, finding that even mild challenges can alter the gut microbiome, leading to changes in health indicators such as beak color and stress hormone levels.
Researchers developed an AI tool to predict patients at risk of intimate partner violence, using data from medical visits. The tool achieved high accuracy in detecting IPV among patients, with the multimodal fusion model outperforming others, detecting risk 88% of the time.
Researchers discovered a freshwater alga that captures far-red light for photosynthesis by rearranging ordinary chlorophyll. This unique strategy allows the alga to thrive in shaded forests and murky waters, making it resilient in tough environments. The findings have practical implications for sustainable bioenergy production and may ...
Scientists extracted thousands of years' worth of air pollution from a 9.5-meter ice core, recording medieval mining, fires, and volcanoes. However, global warming is destroying this frozen archive, and researchers warn that it's a race against time to capture critical climate information.
Researchers at Osaka Metropolitan University discovered how shifting electric fields control light-emitting efficiency in devices like LEDs. By probing electron spin resonance, they found optimal electric field conditions for efficient recombination, leading to higher electroluminescence efficiency.
Studies report that improperly disposed wet wipes can break down into microplastics, polluting rivers and harming aquatic life. Researchers analyzed 72 product labels, finding that only 7% clearly indicated safe disposal methods.
Multicultural intergroup dialogue improves holistic support for international students at Japanese universities. The approach, based on Intergroup Dialogue, promotes equitable and inclusive university environments, where students from diverse backgrounds interact and learn with one another.
A sea urchin single-cell RNA-seq atlas reveals dynamic changes in cell states during neural differentiation. The study provides an accessible platform for exploring gene expression patterns, enabling detailed analysis of neurogenic lineages and regulatory dynamics.
The study highlights the importance of personalized features in healthcare apps to promote physical activity. Key findings include the need for educational components, timely feedback, and tailored exercise suggestions to support users' daily routines and work demands.
In prenatal development, fetal hepatocytes maintain high anabolic activity despite low glucose conditions due to TRPV4 acetylation, which prevents mTORC1 inhibition. This unique nutrient-sensing system safeguards fetal development and enables rapid growth.
Researchers developed a novel magnetorheological fluid-based soft robot with reversible t robot with reversible for precise targeting of gastrointestinal tract diseases. The robot demonstrated stable flip, steering, and folding motions, as well as reliable movement performance under load, and successfully attached to the drug release p...
Bone char produced from animal bones can transform a large global waste stream into a valuable agricultural resource, recycling phosphorus and improving soil health. Laboratory and field studies show that bone char can enhance soil fertility by gradually releasing phosphorus over time, reducing nutrient losses and promoting plant growth.
Experts will address critical issues in voluntary assisted dying and dementia, including community attitudes, Indigenous perspectives, and organ donation. The conference, open to the media and public, features over 130 presentations on VAD and its intersection with dementia.
The Sylvester Cancer Tip Sheet for March 2026 highlights the importance of genetic testing for cancer risk assessment. Researchers have made significant progress in developing new treatments, including mRNA-based immunotherapy for colorectal and pancreatic cancers. Additionally, the Dolphins Cancer Challenge has surpassed $100 million ...
Researchers at Nagoya University present six advances in gallium oxide thin-film growth, including a world-first result growing the material on low-cost silicon substrates. The new High-Density Oxygen Radical Source doubles atomic oxygen density, promoting chemical reaction and film growth.
A new imaging test, PSMA PET/CT scan, has been shown to safely reduce the number of biopsies needed for suspected prostate cancer, with no harm to patients. The PRIMARY2 trial found that the scan could identify low-risk patients who did not need a biopsy, while targeting suspicious areas for those who did.
A new study suggests that using virtual reality (VR) to explain medical procedures can help patients better understand their treatment and reduce anxiety. The research tested VR as part of the consent process for a procedure to treat kidney stones, with patients reporting improved understanding and reduced anxiety after the experience.
A report calls for stricter regulation of AI toys to ensure 'psychological safety' in young children. The study found that AI toys often misread emotions, struggle with developmentally important play types, and pose concerns for social and pretend play.
Researchers at the Netherlands Institute for Neuroscience identified 7 distinct types of hyperarousal, a key factor in various mental disorders. The study suggests that a new, concise questionnaire can help better understand and treat these conditions, leading to more targeted treatment plans.
Researchers developed a solvent-free method to transform biochar into a hydrophobic material that repels water and absorbs oil. The material, created through mechanochemical functionalization, was applied to hemp fibers, providing strong water repellent properties while allowing oil absorption.
Autistic pupils in specialist resource centres exhibit improved academic progress and sense of belonging compared to mainstream schools. However, teacher and peer support are the strongest predictors of positive outcomes, including reduced internalising symptoms and increased flourishing.
A new study challenges the assumption that only small pores in biochar capture carbon dioxide, finding that larger pores significantly increase carbon capture at higher temperatures. The research suggests optimizing the full pore hierarchy of biochar could improve its performance as a carbon capture material.
Researchers directly measured lithium dendrites' mechanical strength, finding they exhibit unexpectedly high strength and brittle behavior under stress. The study provides insights into how dendrites respond to physical stresses within a battery cell, shedding light on the challenge of scale and access that hindered previous research.
Researchers deploy electrical resistivity tomography to characterize subsurface groundwater under the playa, revealing a complex patchwork of fresh and salty aquifers. The study aims to understand the groundwater's volume and flux, advancing knowledge of terminal lakes and their ecological importance.
Researchers are using a revolutionary radar system to transform understanding of lightning and electrification, helping to improve storm warnings and assess damage risk. The system, named Horus, can capture rapid scans of storms, allowing for clearer pictures of lightning plasma and its distinctive polarimetric indicators.
Researchers at MIT developed a new method that coaxes AI models to achieve better accuracy and clearer explanations in safety-critical applications. The approach extracts concepts the model has learned while training for a specific task and forces it to use those, producing better explanations than standard concept bottleneck models.
A new medical technology development initiative, DBS Lead Lock, aims to refine deep brain stimulation lead fixation for improved precision and efficiency. The project, in collaboration with the Marshall Advanced Manufacturing Center, is currently in prototype development.
The Stanley Family Foundation has renewed its $1 billion commitment to psychiatric research at Broad Institute, transforming the field of psychiatric genetics and schizophrenia/bipolar disorder research. Human genetics data from the Stanley Center has provided unprecedented clues to the brain biology underlying these conditions.
A new manufacturing strategy for semiconductor quantum dots has been developed, offering advantages for light-based technologies. The method produces single and entangled photon emitters with low surface density, high symmetry, and wavelengths suitable for integrated photonics.
A 12-month cost analysis of a falls prevention clinic in Canada found that every dollar invested yielded substantial financial and health returns, preventing falls by 36% and providing significant cost savings. The clinic's goal is to keep older adults independent, maintaining their health and quality of life.
A new study from Dartmouth College finds that social information can significantly impact how people experience negative events, including physical pain and mentally demanding tasks. When others describe an experience as painful, individuals tend to feel it that way, even when the actual experience is low in intensity.
A Cleveland Clinic analysis of nearly 8,000 patients found that discontinuing semaglutide and tirzepatide does not lead to significant weight regain in clinical practice. Many patients successfully stabilized their weight after one year through alternative treatments and therapeutic lifestyle interventions.
The American Meteorological Society strongly opposes the dismantling of NCAR, highlighting its central role in atmospheric sciences and its impact on the nation's economy. The AMS recommends that NSF engage in a rigorous process to develop a strategy for enhancing scientific innovation in the weather enterprise.