Researchers identified molecular differences in saliva after a full night's rest and 24 hours without sleep, creating a potential non-invasive test for sleep deprivation. The 'sleepiness fingerprint' holds promise for roadside checks and other situations where accurate detection is needed.
A new study found that irregular sleep patterns, including variability in timing and duration, are associated with lower receptive vocabulary and visuospatial memory scores in preschool-age children. Despite accounting for total sleep time, greater variability in sleep midpoint was linked to lower verbal performance.
Adolescents with irregular sleep and insomnia symptoms have higher odds of overnight hospital stays and poorer general health in their 20s. Poorer sleep health during adolescence is associated with a range of negative outcomes, including lower life satisfaction and reduced overall well-being.
The American Heart Association has named eight companies to its Heart and Brain Health Accelerator, a program designed to advance innovative technologies in cardiovascular health. The selected companies will receive mentorship, coaching, and capacity building from the American Heart Association Ventures.
Adults with lower measured glomerular filtration rates had a higher risk of all-cause mortality, kidney failure, and major adverse cardiovascular events. Lower GFR values were also associated with increased hospitalization for heart failure and acute kidney injury.
Researchers developed a system to link polyphenol chemical structures with bitterness, acidity, and astringency. Polyphenols found in tea, cocoa, and other foods influence taste sensations, affecting food preferences and digestive responses.
Researchers discover that breast cancer cells exploit protective systems in bone marrow to remain dormant, using Notch2 signaling and genes like CXCR4 and TIE2. This dormancy allows cells to reactivate years later, leading to secondary tumors.
In patients with advanced chronic kidney disease at high cardiovascular risk, low-dose rivaroxaban did not reduce the composite risk of a cardiovascular outcome. Major bleeding rates were significantly higher in the low-dose rivaroxaban group compared to the placebo group.
A pioneering pilot clinical trial showed that spinal cord stimulation improved arm strength by 32% in stroke survivors, with significant reductions in muscle spasticity. The intervention required minimal training time and was safe with no serious adverse events.
A digital 'super-brain' with physics-based knowledge significantly speeds up the design and development of optical components, such as those for quantum computers and camera lenses. By integrating physical principles into machine learning algorithms, researchers reduce simulation time from months to days.
Researchers at Lehigh University developed a new gold-palladium catalysis mechanism that increases reaction rates and stabilizes catalysts. This breakthrough advances the development of more efficient bio-based chemical manufacturing processes.
Researchers have described two new Hydropsyche species from the Middle East and Caucasus, highlighting the importance of traditional morphological examination and advanced DNA analysis. The discoveries, made in Azerbaijan, Iran, and Türkiye, underscore the region's vast potential for new aquatic species yet to be found.
A new study reveals that ancient Britons likely transported the Altar Stone of Stonehenge 700km across challenging terrain, requiring careful planning and coordination. The research uses mineral grain dating and ice-sheet modeling to confirm human transport over natural Ice Age processes.
Researchers found that pregnant Pacific pocket mice trained to fear snakes produce more vigilant offspring, which survive better in the wild. This method of antipredator training may improve conservation breeding and reintroduction programs.
Researchers at Georgetown University Medical Center found that the brain can remodel its architecture to automate learned tasks, enabling true multitasking. This challenge previous theories on human multitasking and has implications for artificial intelligence capable of building on prior learning.
A Korean research team developed a new technology to prevent electrolyte layer cracking in solid oxide electrolysis cells. The new design improved Faradaic efficiency and current density, achieving highly efficient conversion of CO2 into carbon monoxide.
Researchers propose a framework for on-demand atmospheric observations using lightweight, low-cost profiling systems to improve short-term forecasting and climate resilience. Community-operated systems could fill critical gaps in existing forecasting systems, particularly in remote regions.
Residents in informal Lagos settlements have developed sophisticated climate adaptation systems, including drainage systems and plastic waste management, to stay safe during flooding. Despite government policies dismantling their homes, they continue to earn income from providing climate-related services.
Researchers developed multifunctional metal–organic framework nanoparticles that degrade HK-2, suppress glycolysis, and induce cuproptosis. CHNDs showed stronger anticancer activity than either the HK-2 degrader or the copper nanoplatform alone, disrupting protein homeostasis and cancer energy metabolism.
Researchers at Nagoya University identified the neural circuit responsible for timing torpor in mammals, which reduces body temperature and metabolism. The discovery provides new insights into how animals regulate energy use.
A recent study published in Eye Discovery identified a coordinated failure of tissue regeneration and vascular control in corneal alkali burns. The research found that limbal stem cells, transient amplifying cells, and macrophages form an amplified VEGF communication network, leading to excessive vascular growth and vision loss.
UJI researchers recognized for their work in social psychology and psychosocial prevention, with focus on occupational health psychology and development of diagnostic tools. Researchers from various departments rank among the top 300 women scientists in Spain.
Researchers identified two weather patterns associated with an increased risk of headaches in the Northeast US. The study found that approaching cold fronts and high-pressure systems, such as the Bermuda High, can trigger new-onset headaches in people with episodic migraines.
Researchers found that reef manta rays stay within 10km of their tagging site during monsoons, expanding their vertical use of the water column rather than traveling long distances. This suggests they can change behaviors to adapt to ocean conditions and protect themselves from threats like overfishing.
Researchers have developed a novel nano-space confinement strategy for hard carbon anodes, overcoming limitations in sodium-storage mechanisms. The optimized material delivers high reversible capacity and maintains rate capability, making it suitable for next-generation sodium-ion batteries.
Researchers at the University of Tokyo have discovered a method to quantify CO2 absorbed by cementitious materials and its atmospheric contamination using carbon isotope measurements. This breakthrough aims to improve carbon accounting and reduce greenhouse gas emissions in concrete production.
In a study on Japanese macaques, researchers found that semi-shade is an important thermoregulatory option under hot, dry conditions. The macaques preferred semi-shade over full shade or sun when it was hot and dry, but not humid. This suggests that semi-shade may play a significant role in helping endotherms cope with heat stress.
A study of over 1,000 people vaccinated with TAK-003 in Catalonia found no serious adverse events and provided new evidence on the vaccine's short-term safety in travelers. The findings suggest that the dengue vaccine has a good tolerability profile among travelers from non-endemic regions.
A study found that patients continuing ULT remained flare-free for longer over 24 months, with a cumulative flare incidence of 12.3% compared to 31.8% in the ULT discontinuation attempt group. Effective weight management and exercise are key to managing gout and rheumatoid arthritis.
Despite overall declines in child mortality, progress has stalled, particularly among newborns and children under 5, who face major causes like preterm birth complications and pneumonia. Renewed commitment and investment are crucial to prevent an unfolding tragedy and meet international child survival targets.
A UK study found that parents often rely on manufacturer instructions, social media, and babywearing websites for guidance on using baby carriers safely. The research calls for a UK-wide campaign to direct parents to trusted sources of guidance and specialist advice.
Eight healthcare peers urge MPs to support urgent law reform on assisted dying, citing risks to dying people and public trust. The Bill aligns with best practices from overseas, including assessing capacity, informed consent, and safeguards.
Phosphorus and nitrogen, two elements necessary for life, were found in distinct ratios in asteroidal bodies related to iron meteorites compared to younger asteroids. Researchers recreated the crystallization of iron meteorites in the lab and analyzed their chemical composition, which suggested that these life-essential elements origin...
Tiny warty birch caterpillars can distinguish between the approaching footsteps of deathly ladybeetles and invading caterpillars. When threatened, they make a lot of noise to scare off the attacker, but when faced with an intruding ladybug larva, they become silent before deciding to evacuate or throw themselves off the leaf.
Spatial arthroscopy integrates surgical video feeds with advanced hardware and software systems, enabling a heads-up display that keeps surgeons focused on the field. This technology improves ergonomics and opens doors to future capabilities like voice commands and automated documentation.
Researchers found high levels of antidepressant drugs in four North Carolina rivers, exceeding toxic thresholds for aquatic life. The study highlights the need for effective remediation strategies to mitigate environmental contamination and human health risks.
The FLOW trial shows that semaglutide significantly improved health-related quality of life in adults with type 2 diabetes and chronic kidney disease. Health utility scores and self-rated general health scores improved with semaglutide, but declined with placebo.
A study combining citizen science data with experimental research found that switchgrass adapts its flowering time to optimize survival in different regions. The work highlights the potential of pairing public data sets with controlled experiments to uncover mechanisms of adaptation.
A new study by the American Cancer Society finds that nearly five million Americans live in food deserts, where grocery stores are scarce. The number of food swamps, areas with mostly restaurants and fast-food locations, has increased nationwide.
Researchers at the Institute of Industrial Science, The University of Tokyo, analyzed new dataset to identify temporal variations in locking state of the Nankai Trough. Variability was found particularly in shallowest parts of plate boundary, influencing earthquake strength and size.
The university's patented technology assists surgeons in detecting and visualizing significant arterial bleeding using augmented reality overlays, enabling precise control and quick action. This innovation aims to improve patient outcomes, save lives, and reduce hospital stays, infection rates, and treatment costs.
Researchers from Pennington Biomedical will showcase their latest findings on prevention, care, and cures for diabetes and obesity at the American Diabetes Association's 2026 Scientific Sessions. The sessions will highlight cutting-edge advancements driving progress in diabetes research and management.
A new collection of Frontiers for Young Minds articles reviews breakthrough brain research topics, including artificial intelligence and memory. Young reviewers aged 8-15 collaborated with leading neuroscientists to make complex neuroscience topics accessible to their peers.
A recent clinical trial demonstrated that an all-oral drug combination of decitabine-cedazuridine and venetoclax is effective in treating acute myeloid leukemia (AML) in older patients. The regimen showed strong response rates and survival outcomes, with nearly half of patients achieving complete response.
A pioneering clinical trial demonstrates CAR T cells can safely desensitize highly sensitized patients, making kidney transplantation possible. Two patients with end-stage kidney disease successfully received kidney transplants after years of waiting.
A new iron-modified biochar catalyst activates natural oxygen and iron cycling in farmland soil, breaking down sulfamethoxazole at a 4.2-fold increase under laboratory conditions. The material also achieved strong pollutant removal, with degradation reaching 81.2% under favorable soil moisture conditions.
Long-term biochar study reveals that topsoil benefits from biochar's effect on microbial necromass carbon, with significant increase in fungal necromass carbon. In contrast, subsoil shows reduced microbial necromass carbon due to lower nitrogen availability and increased microbial nutrient mining.
A new study found that rice straw biochar applied at moderate levels improved several colony behaviors linked to soil health in ants. Ants showed stronger habitat preference, built larger nests, and maintained more effective social recognition. However, high doses of biochar were detrimental, causing ant survival to drop sharply.
Researchers examine the process of prioritizing river restoration projects using a mathematical computer program called optimization. The study shows that score and rank systems don't always account for barriers in the full river context, leading to stranded investments.
Scientists at the SETI Institute searched for technological signals from 3I/ATLAS, a natural comet-like object from another star system. Despite extensive scanning, no technosignatures were detected, setting new constraints on the power of any radio transmitter on or near 3I/ATLAS.
A new research initiative aims to harness the potential of astrocytes, a type of brain cell often overlooked in AI development. By studying how astrocytes process information, researchers hope to create next-generation AI systems that learn faster and adapt more reliably.
A new proactive treatment protocol, PACT, combines medication and frequent follow-up to prevent alcohol relapse after liver transplant. Researchers found a 0% heavy alcohol relapse rate among patients who followed the protocol, compared to a historical rate of approximately 25%.
Researchers from Drexel University developed BioCoach, a program using AI and computer vision to analyze video and provide form coaching in real time. The system analyzes visual appearance and motion patterns, as well as 3D skeletal movements and body shape, to deliver detailed biomechanics-based feedback.
A study by the American Academy of Neurology found that people with epilepsy living in rural areas had poorer health outcomes, including higher mortality rates, longer hospital stays, and reduced access to specialized care. The study highlights the need for improved access to epilepsy care in rural areas.
A University of California, Davis study found that adding 'high sugar' warning labels to restaurant menus can significantly reduce added sugar consumption among diners. The study tested two types of labels and found that diners ordered an average of 10 grams less added sugar when the labels were present. This amount is substantial, con...
A new study reveals how Philip Morris Companies Inc. used cigarette research and flavor engineering to design Lunchables, a successful ultra-processed food for children. The company's strategy was based on optimizing 'technical synergies' between tobacco and food divisions.
Researchers at Viva Bem have developed an AI method that identifies states of anxiety with high accuracy using smartwatch data. The technology aims to provide a layer of proactive monitoring for users, alerting them to recurring anxiety episodes and recommending specialist consultation.
Research studies reveal suboptimal adherence to treat-to-target strategies in rheumatoid arthritis, with lower rates among spondyloarthritis patients. Additionally, data from registries show the potential benefits of glucagon-like peptide-1 receptor agonists for weight loss and disease activity management in RMD.
A University of Mississippi-led study reveals counties in the US Deep South with high HIV rates and limited access to prevention tools. Public health leaders can use a prevention gap index to identify areas for targeted intervention and allocate resources effectively.
A team of researchers discovered that coffee molecules, such as melanoidins, significantly reduce the bitterness of caffeine. When combined with chlorogenic acid, these compounds halve the bitter taste of caffeine, suggesting a complex formation prevents interaction with bitter taste receptors.