A study found that older adults are prescribed potentially inappropriate central nervous system-active medications despite guidelines. Patients with cognitive impairment were more likely to receive these medications than those with normal cognition. The study highlights the need for better medication management in older adults.
A new study led by NTU Singapore reveals that El Niño events can persistently slow long-term improvements in mortality rates, leading to enduring reductions in life expectancy. The research estimates that El Niño could reduce life expectancy gains by 2.8 years and cause economic losses of up to US$35 trillion by 2100.
A new study by the University of Stirling has found that introducing parkwalkers to parkrun events has led to a surge in walker participation. The initiative has increased the proportion of new female participants and reversed a decline in the average age of new attendees.
The inaugural JACC Cardiovascular Statistics report examines five major CVD risk factors and conditions, revealing persistent disparities by race, geography and socioeconomic status. The report identifies critical gaps in data and opportunities for innovation to improve US heart health.
A recent study found that people globally perceive themselves as less at risk of climate change than others, with the effect most pronounced among Europeans. This 'self-other' discrepancy may delay necessary action and hinder climate adaptation and mitigation efforts.
Materials and Solidification journal focuses on original research on solidification of various materials, including metals, semiconductors, and polymers. The journal covers topics like solidification processing, non-equilibrium phenomena, and multi-physical fields.
A team led by Prof. Richard Gu has developed an automated robotic nanoprobe that can navigate within living cells, sense metabolic whispers in real time, and pluck individual mitochondria without causing damage or fluorescent labeling. The breakthrough holds great promise for advancing treatment strategies for chronic diseases and cancer.
Dr. Gang Hu, a leading expert in chronic disease epidemiology, has been appointed to the NIH Reproductive, Perinatal and Pediatric Health Review Group. He will evaluate studies on reproductive, perinatal, and pediatric health, with a focus on lifestyle factors and their impact on chronic diseases.
Researchers at KAIST have developed a new OLED technology that more than doubles screen brightness while maintaining the flat structure of OLED displays. The new technology uses a thin, near-planar light outcoupling structure and an OLED design method to significantly reduce light loss inside OLED devices.
A study published in the British Medical Journal identified key criteria for evaluating mobile apps for managing depression, including data safety, clinical efficacy, and intuitive design. The EvalDepApps tool aims to help patients and health professionals choose effective apps by providing clear indications.
The ACET-Estonia project partners to co-design and deliver applied clean energy research, fostering innovative solutions for Estonian island communities. Canadian expertise supports international partners in addressing similar energy challenges.
A new clinical trial, PAGODA, seeks to minimize treatment interruptions and help patients complete their chemotherapy as planned. The trial will test a structured plan to guide doctors in making small, proactive changes to chemotherapy doses to prevent treatment delays.
Lisa Wald, a renowned USGS scientist, has been honored by the Seismological Society of America for creating the Earthquake Hazards Program's information hub. Her groundbreaking work made a wealth of earthquake information accessible to everyone, from the general public to seismologists and governments.
Researchers at QST discovered that controlled gamma-ray mutagenesis can create heat-tolerant nitrogen-fixing bacteria in weeks, shortening development timelines. The method produces robust, climate-ready microbial products for agriculture, food processing, pharmaceuticals, and biofuel production.
Researchers have developed a blood test that can predict Crohn's disease years before symptoms appear. The test measures immune response to flagellin, a protein found on gut bacteria, which is elevated in individuals long before they develop the disease.
A recent study reveals that over 680,000 new cases of hepatocellular carcinoma were estimated worldwide in 2022, with 78.4% attributable to nine modifiable risk factors. The majority of HCC cases are preventable, and the study emphasizes the need for targeted preventive programs.
A new plant-based hydrogel has been developed to tackle the problem of metallic zinc growing needle-like dendrites that short-circuit cells within a few hundred cycles. The cellulose-nanofiber dual network boosts ion flow and mechanical strength, delivering a cheap and biodegradable electrolyte.
Insilico Medicine's Phase IIa clinical trial assesses Garutadustat's safety and efficacy in ulcerative colitis. The novel PHD inhibitor has shown favorable safety and tolerability profiles in completed Phase I studies.
A large-scale population genomic study has shed new light on the evolutionary history of the button mushroom (Agaricus bisporus), one of the most widely cultivated edible fungi in the world. Climate dynamics and a key gene for adaptive evolution and domestication jointly shaped the mushroom's diversity.
Research found that prolonged heavy drinking induces neuroinflammation, promoting negative emotional states lasting for weeks into abstinence. Inhibiting proinflammatory microglia activation during alcohol exposure blocks the development of anxiety and fear memory.
The Berlin Aging Study (BASE) dataset is now publicly accessible, providing detailed longitudinal data on health and well-being. Researchers can explore the connections between physical, psychological, and social factors and aging, shedding light on why people age differently.
Korea University's Institute for Environmental Health trained faculty members from Karakalpakstan Medical Institute to improve environmental health in the region. The training aimed to enhance water quality and waste disposal management, fostering collaboration and joint research.
Abhishek Mishra receives a prestigious $160,000 postdoctoral fellowship from the American Heart Association to explore the molecular mechanisms of heart failure with preserved ejection fraction. The funding will support Dr. Mishra's research on PTP1B inhibition as a potential therapeutic strategy for cardiometabolic diseases.
Georgetown University researchers discovered a method to enhance the function of T cells, making them more effective in killing cancer cells. By inhibiting PARP, an enzyme that detects DNA abnormalities, scientists can boost the body's immune response against tumors.
Researchers propose a roadmap for using transcranial focused ultrasound to study consciousness, enabling precise manipulation of brain activity and determining cause-and-effect patterns. This technology may help address the hard problem of consciousness by probing neural circuits that generate sensations, thoughts, and feelings.
A team of material scientists created a machine learning model that predicts gas-sensing performance using first-principles calculations. The model achieved a prediction accuracy of 96% in five-fold cross-validation and F1 scores of 1.000 and 0.933 in independent test sets.
JMIR Publications' JMIR Neurotechnology journal now accepts submissions on novel technological advances for neurological disorders. Researchers can submit review articles exploring emerging technologies, such as neurofeedback, neurosurgery, and brain-machine interfaces.
A team of researchers from Chonnam National University has developed a novel superpixel-based virtual sensor framework for full-field vibration measurement. The approach offers robust and accurate motion estimation without the need for physical markers or contact sensors, making it suitable for large-scale infrastructure monitoring.
Researchers at Institute of Science Tokyo have discovered a stable superfluid that inherently hosts singularities known as exceptional points. The study reveals how dissipation can stabilize this unique superfluid phase, which features a finite order parameter and emerges deep inside a strongly interacting phase.
Researchers identified cilia-mediated Hedgehog signaling as a key regulator of tooth development. The study found that disrupting Cilk1 levels can lead to stepwise changes in tooth formation and morphology, including extra teeth or fused molars. This discovery may support earlier diagnosis for children with ciliopathies.
Pangenomics is the study of many different genomes from one specific species, providing a holistic picture of natural variation and mutations. A new data structure and compression technique, PanMAN, enables researchers to handle vast genetic data scales by encoding additional biologically relevant information.
Researchers developed an algorithm using whole-genome sequencing to detect homologous recombination deficiency, a type of DNA-repair defect vulnerable to PARP inhibitors. The approach identified genetic mutations beyond BRCA1 and BRCA2, promising more accurate patient selection for cancer treatment.
A new study in Circulation: Population Health and Outcomes journal found that TV characters were more likely to receive CPR than real-life counterparts. This discrepancy highlights the need for accurate depictions of hands-only CPR on television.
Astronomers have spotted an ancient galaxy that was slowly starved of fuel by a supermassive black hole. The galaxy's lack of cold gas prevented it from forming new stars, despite its relatively young age. Repeated episodes of heating and gas removal by the black hole likely drained the galaxy's fuel in as little as 16-220 million years.
A California statewide study found that an expanded school-based tobacco prevention program was associated with significantly lower rates of smoking and vaping among middle and high school students. Students in funded schools were 20% less likely to use tobacco overall and 23% less likely to vape.
A new study from University of Southern Denmark reveals that weight loss improves the health of fat tissue, reducing inflammation and immune cell activity. Moderate weight loss also promotes the formation of new and healthier fat cells, leading to improved insulin sensitivity.
Researchers have imaged a beautiful shock wave around a dead star, RXJ0528+2838, which challenges our current understanding of how dead stars interact with their surroundings. The team found that the white dwarf has been expelling a powerful outflow for at least 1000 years, driven by its strong magnetic field.
A Japanese research team has developed a biohybrid approach that works inside the body, transforming engineered skin into a visible indicator of internal biological states. The system leverages the body's natural skin regeneration to support long-term biomarker monitoring, providing a visual readout without blood sampling.
Research from Karolinska Institutet found that alpha frequency determines body ownership by modulating temporal integration of bodily signals. Faster frequencies led to higher temporal resolution, while slower frequencies caused broader timing differences.
A study analyzed 169 US TV episodes that portrayed hands-only CPR since 2008 and found nearly half showed outdated practices. Most cardiac-arrest victims receiving hands-only CPR on-screen were white men, while women and Black and Latino people are less likely to receive the intervention in real life.
Researchers propose threshold levels for safe cannabis use, aiming to guide consumption and reduce harm. The recommended limit is 8 THC units per week, above which the risk of developing cannabis use disorder increases.
A new study published in CANCER found that men are more likely to have advanced disease and high myeloma load at diagnosis compared to women. Men were also less likely to have low bone mineral density and had different chromosomal abnormalities, which may contribute to the sex disparity in multiple myeloma risk.
Scientists at VIB and KU Leuven discovered a molecular process that enables motor neurons to maintain protein production, which fails in ALS. By restoring protein synthesis in axons, they reduced disease-related damage in ALS models.
Research from Radboud University Medical Center and colleagues demonstrates the value of targeted tumor analysis of DNA in colorectal polyps. This study provides valuable insights into genetic predispositions, including APC mutational mosaicism and BRAF gene mutations.
New research suggests that mobile health interventions tailored to individual needs can reduce harms associated with heavy drinking and cannabis use. Studies demonstrate the effectiveness of personalized feedback and protective behavioral strategies in reducing substance use risks, paving the way for innovative digital interventions.
Healthcare professionals in Canada assess applicants for medical assistance in dying (MAiD) using a careful and individualized approach. They consider the patient's life circumstances, support networks, and personal preferences when determining eligibility. The assessment process is often legally and morally complex, requiring provider...
Researchers redesigned a superconducting solenoid to significantly reduce spherical aberration and improve electron beam emittance. The new design achieved a 47% reduction in transverse emittance under high-intensity beam conditions.
A new metamaterial design enables real-time stiffness visualization and self-sensing capabilities, paving the way for intelligent systems. The research team created a linear relationship between stiffness and active hinges, allowing for precise tuning and adaptation in mechanical systems.
A team from Chongqing Medical University developed a model that integrates sMRI and fMRI data to predict treatment responders, achieving high accuracy rates. The dual-branch graph attention network (DBGAN) captures coordinated brain changes linked to emotion regulation and memory processing.
A new study from Murdoch University found that 66% of participants with Complex Regional Pain Syndrome (CRPS) experienced migraines that started or worsened after CRPS onset. This research highlights the connection between CRPS and migraine, suggesting a possible common cause for both conditions.
A tiny sensor developed by KAUST researchers can detect hazardous head impacts with 360-degree accuracy, distinguishing minor bumps from severe blows. The device's innovative design allows it to operate without power or routine upkeep, paving the way for next-generation wearable safety systems.
Researchers developed a novel theory that enables precise control of heat conduction in materials with asymmetric microstructures. This innovation has potential applications in energy harvesting and protecting heat-sensitive electronics.
The research team led by DGIST Professor Su-Il In developed a high-performance next-generation betavoltaic battery with an energy conversion efficiency of 10.79%. This is a significant improvement over the previously reported highest efficiency for perovskite-based betavoltaic batteries.
Astronomers have discovered that black holes don't just consume matter — they manage it. Researchers found that black hole binary systems switch between powerful jets and energetic winds—never producing both simultaneously—and both types of outflows carry away comparable amounts of mass and energy.
A new study assesses the EU Energy Performance of Buildings Directive through a social justice lens, highlighting how renovation policies can widen existing social inequalities. The Composite Building and Social Vulnerability Index reveals markedly different levels of vulnerability across EU countries.
A novel deep learning model, LA-TextCNN-BiLSTM, has been developed to improve the accuracy of automatic disease classification using ICD-11 for Chinese Electronic Medical Records (EMRs). The model achieved an 83.86% accuracy rate and demonstrated robust performance in multi-label classification.
Researchers have developed a strategy to enhance the stability of CsPbI3 perovskite nanoplatelets by incorporating formamidinium, which improves bulk thermodynamic stability and surface ligand binding. This approach leads to highly oriented superlattices with improved linear polarization of light emitted.
Researchers detected up to 500 microscopic plastic particles per square meter per day in a rural woodland area, almost twice as much as in an urban location. The study reveals that trees and vegetation capture airborne microplastic particles from the atmosphere.
Veteran male athletes over 50 are more likely to experience abnormal heart rhythms during training if they have scarring in their hearts. Exercise itself is not the cause, but can act as a trigger for dangerous heart rhythms in those with underlying heart issues.
Researchers in Hong Kong will have greater opportunities to share their work with a global audience through an open access agreement between JULAC and Taylor & Francis. The partnership enables OA publishing in over 2,000 journals without payment of an OA article publishing charge.