The NUS-IHME Global Burden of Disease Research Centre aims to bridge the gap between longevity and healthy ageing by examining the impact of extreme heat, antimicrobial resistance, and other environmental shifts. The centre will provide critical data and insights to inform health strategies across Southeast Asia.
Researchers have demonstrated an angstrom-scale electroplasmonic platform enabling giant modulation (2000% V⁻¹ ) of near-field nonlinear optical effects across a broad spectral range. The discovery provides a novel scheme for highly efficient electro-optical conversion in an infinitesimal spatial scale.
The study found that students with physical disabilities reported higher overall quality of life scores compared to those with visual and hearing impairments. The research team recommends expanding inclusive sports programs and social activities tailored to sensory impairments.
Researchers have identified MDGA2 as a causative gene for developmental and epileptic encephalopathy (DEE), a rare neurological disorder. The study highlights the potential for early diagnosis and new therapies to modulate MDGA2 function or reduce excessive excitatory signaling in the brain.
Researchers developed a phase multiplication technique harnessing laser feedback and cavity dynamics to enhance ranging resolution. Higher-order harmonics exhibit higher phase sensitivity, allowing for improved measurement accuracy.
Researchers have discovered a crucial pattern of gene evolution that appears significant for the origin and diversification of vertebrates. The study found diverse protein variations in sea squirts, lampreys, and frogs, which shed light on how animals with backbones evolved.
Vinay Badhwar, MD, was elected President of The Society of Thoracic Surgeons with a three-part framework emphasizing daily practice excellence, data-driven science, and measurable impact. He aims to advance collaboration across surgical disciplines and integrate the specialty into the broader healthcare ecosystem.
A systematic nuclear data evaluation of the five-nucleon 5^He system was performed using the Generalized Reduced R-matrix framework. The study provides reliable cross-sections with improved uncertainties, covering energy ranges up to 46 MeV for neutron-induced reactions and 30 MeV for deuteron-induced reactions.
Researchers measured energy correlations between two 252Cf prompt fission neutrons, finding a positive correlation at 180° and a negative correlation at 90°. These findings are crucial for developing and verifying fission physics theories, and should be considered in neutron coincidence and multiplication measurement techniques.
Ascending aortic hemiarch replacement is comparable to extended arch reconstruction for patients over 65 with acute type A aortic dissection. The study found no significant difference in long-term survival or surgical reintervention rates between the two procedures.
The European Commission and ECMWF have signed an agreement for the third implementation phase of DestinE, a digital twin project aiming to improve AI climate and weather predictions. The project will start in June 2026 and focus on operating and interlinking digital twins, as well as developing AI capabilities further.
A late-breaking study analyzing over 2.1 million patients found that bilateral internal thoracic artery (BITA) and single internal thoracic artery plus radial artery (SITA+RA) strategies offer comparable long-term survival overall. The study suggests that patient age may play a crucial role in selecting the optimal conduit strategy.
Researchers analyzed cases in the STS Adult Cardiac Surgery Database to identify factors predicting postoperative risk. The study found that 16.7% of adults nationwide with CHD were considered high-risk for operative mortality and serious complications after redo cardiac surgery.
Breakthrough research recommends that more than one N1 node be removed and evaluated during surgery for non-small cell lung cancer (NSCLC). The study found that many cancers were identified in N1 nodes adjacent to the bronchi, highlighting the need for expanded lymph node evaluation.
A novel radiation therapy QA method has been developed by combining Monte Carlo simulation with deep learning to generate patient-specific dose verification. This integrated technology accelerates quality assurance and paves the way for efficient online adaptive radiation therapy.
Researchers developed an AI tool called ONCO-ACS to predict the risk of secondary heart attacks in cancer patients after a heart attack. The tool combines cancer-related factors with standard clinical data to provide reliable information for doctors to balance treatment benefits and harms.
The Muonium-to-Antimuonium Conversion Experiment (MACE) aims to detect the rare conversion of muonium into antimuonium, a process that could reveal new physics. The experiment seeks to improve upon the last experimental limit by more than two orders of magnitude and target a conversion probability as low as 10^-13.
Researchers introduce a framework linking biochar's internal structure to its performance in various applications. The physical genome framework unifies scattered findings and encourages future studies measuring multiple properties.
Researchers at Tsinghua University developed a novel method for synthesizing chiral alpha-amino acids using a photo-driven nitrogen heterocyclic carbene catalyst. The reaction achieves good to excellent enantioselectivity and substrate versatility, enabling the rapid preparation of structurally diverse chiral alpha-amino acid derivatives.
Cells move in groups during biological processes, but researchers have made a surprising discovery that upends understanding of how cells move. Negative viscosity, which propels cells forward, has been found to increase metabolic activity in affected regions.
A comprehensive review evaluates the global race to track urban carbon emissions, highlighting the importance of high-precision atmospheric observations. The study reveals a stark geographical divide between monitored and unmonitored cities, emphasizing the need for a transparent framework for carbon neutrality.
Iakovos Toumazis leads IDSO's focus area on decision analytics for health to optimize patient outcomes and resource allocation. His research informs data-driven approaches to cancer prevention and policy decisions.
Researchers develop biochar-based phase change material that captures, stores, and releases heat with high efficiency while locking carbon away. The resulting material stores nearly twice as much latent heat as lower-temperature versions.
A study tracking nearly 1,000 emerging adults found that reports of childhood adversity remained stable but fluctuated over time, influenced by relationship quality. Fluctuations were more pronounced when people reported less support from their parents.
A mobile endoscopy team performed over 500 procedures in rural hospitals across Western Cape, South Africa, revealing a high burden of treatable gastrointestinal diseases. The program substantially reduced patient travel, improving continuity of care and early cancer detection.
The Gerdt Lab at Indiana University Bloomington has found a chemical solution to weaken bacteria's defenses against viruses, providing an alternative to antibiotics. The discovery could apply to hard-to-treat infections in humans and agriculture, where antibiotic overuse can worsen the spread of resistance.
Researchers identified a crucial factor that may help improve treatment for glioblastoma, one of the most aggressive and common forms of adult brain cancer. They discovered a small molecule called miR-181d acts like a master switch that controls how much MGMT is produced by each glioblastoma cell.
The University of East London has launched its first South Asia Careers Hub in Chennai, combining international academic practice with regional perspectives. The hub will focus on areas such as Health and Behavioural Sciences, Engineering, Business Management, and Psychology, aligning with Tamil Nadu's priorities.
Researchers develop a new design strategy for MEMS electrothermal actuators, correcting nonlinearity mechanically by integrating machine learning-optimized metastructures. This approach simplifies system architecture while preserving precision and enabling robust motion in compact environments.
The portable optical sensor uses machine learning to analyze spectral patterns and estimate grape ripeness directly on the vine. This technology promises significant business benefits for winemakers by providing non-destructive, real-time insight into grape ripeness, reducing labor and time required for sampling and analysis.
A new analysis by UC Berkeley researchers found that 'red flag' laws significantly reduced firearm suicides in four states that implemented the laws. The study estimates that these laws prevented over 675 suicides between 2023 and 2024. Non-firearm suicide rates remained unchanged.
Researchers develop a dissolving microneedle patch with embedded bubble structures to co-deliver multiple therapeutics for enhanced local drug availability and therapeutic efficacy in acne vulgaris. The system achieves rapid symptom relief and sustained antibacterial action, overcoming long-standing delivery limitations.
A team of researchers has developed a novel single-photon source that combines on-demand operation with record-high photon quality in the telecommunications C-band. This achievement brings deterministic quantum dot sources into the same performance regime as probabilistic SPDC sources, enabling applications such as measurement-based qu...
A new study by University of Cincinnati economics professor David Brasington found that local business benefits from city services, particularly tax renewals, in Ohio. The research compared communities with renewed taxes and those with cut taxes, revealing a significant difference in commercial property redevelopment.
Researchers have developed a miniaturized microoptical system for continuous, real-time fluorescence monitoring of three-dimensional microtissues directly on chip-based platforms. This technology tracks functional changes in living tissues over extended periods with high accuracy.
The Swiss National Science Foundation has awarded funding to the Paul Scherrer Institute's Muoniverse project, a large-scale collaboration in muon research. The project aims to improve muon beam quality and precision, enabling new research opportunities in materials science, energy, and archaeology.
Researchers developed a chemiresistive gas sensor that dramatically improves ethanol detection by integrating ultrathin catalytic nanosheets onto a conventional metal-oxide sensing film. The resulting device responds strongly to ethanol concentrations spanning from parts per million down to a few parts per billion.
Researchers found that bacteria exposed to perchlorate produce stronger calcium carbonate crystals, leading to better biocementation skills. The presence of guar gum and nickel chloride enhances the process, paving the way for alternative building strategies on Earth and Mars.
A new metasurface approach transforms uneven laser beams into uniform pumping fields, reducing spin decoherence and enhancing signal stability. This innovation improves magnetic measurement performance, enabling more precise and robust quantum sensors.
Researchers developed an EEG-based system to decode pleasure from listener's brain activity and suggest personalized playlists. The system outperformed 'acoustics-only' methods, capturing neural markers of pleasure with high accuracy.
Researchers develop optoelectrowetting-based system for ultra-precise microdroplets, achieving high volume consistency and reproducibility. The system uses programmable light patterns to control droplet formation, eliminating random pinch-off and improving accuracy.
Researchers developed a high-performance electrochemical vector hydrophone with micron-scale control of electrode spacing, achieving higher sensitivity and broader frequency coverage. The device enables the detection of weak and broadband underwater signals in complex marine environments.
Researchers found that eosinophils suppress chordoma growth and induce cell death in tumor cells, suggesting them as a novel immunotherapeutic target. The study's findings provide new insight into the immune mechanisms underlying chordoma progression.
Researchers developed a novel microfluidic strategy for separating flexible microalgae based on size differences. The approach achieves precise separation while preserving cell viability, offering a scalable and energy-efficient alternative to existing technologies.
A Goethe University-led study reveals how mutations in the SPRTN enzyme cause chronic inflammation and premature ageing. The research team found that damaged DNA in the cell nucleus leaks into the cytoplasm, activating defense mechanisms and leading to chronic inflammation.
Researchers introduce a new single-cell sorting strategy operating directly in air to overcome constraints of fixed microfluidic channels. The system achieves exceptionally high accuracy and survival rates, enabling flexible sorting of multiple cell subpopulations from complex samples.
A team from the University of Illinois developed a photobiocatalytic platform that enables Escherichia coli to produce complex molecules through light-driven enzymatic reactions. This breakthrough broadens the capabilities of biomanufacturing, offering a promising avenue for sustainable production of chemicals and materials.
A new study by McGill University researchers offers a potential solution for infant hydrocephalus, a life-threatening condition that affects 1 in 1,000 newborns. RNA therapy has been shown to prevent the condition in mice models, with a promising impact on treating genetically caused hydrocephalus.
A recent study by RIKEN researchers analyzed the effects of pesticides and fertilizers on mandarin oranges in real-world farms across Japan. The findings showed that reducing chemical pesticides led to more fruit diseases, while also enhancing soil microbial diversity and improving carbon content. This trade-off highlights the need for...
The IPCC is hosting two major international workshops at the University of Reading in February 2026 to make reports more inclusive and robust. The workshops will explore how indigenous and practitioner knowledge can be integrated with scientific research to create complete climate assessments.
The University of Ottawa has launched the Ottawa Medical Artificial Intelligence Research Institute (OMARI), a center for research, education, and innovation in medical Artificial Intelligence. Led by Dr. Khaled El Emam, OMARI aims to facilitate cross-cutting collaborations and sharpen the university's competitive edge in AI-driven hea...
Researchers found that meerkats use soft-spoken sunning calls to stay socially connected and manage group hierarchies without direct physical contact. Subordinate meerkats responded more strongly to dominant calls, suggesting vocal exchanges help stabilize weak social relationships.
A new microneedle electrode design integrates a stimulation electrode and local ground to confine electrical currents, reducing lateral and vertical spread. This approach enables highly localized neural activation with more focused stimulation strength.
Researchers demonstrate injection locking strategy to synchronize microwave comb spectrum, reducing frequency fluctuations and phase noise. The approach harnesses mechanical nonlinearity for enhanced stability, paving the way for ultra-stable signal generation in demanding environments.
The DFG Senate Commission emphasizes the need for long-term research programmes and adapted policy frameworks to assess the impacts of diversified cropping systems. These systems, such as extended crop rotation, can improve soil quality, reduce pest pressure, and enhance overall system resilience.
Researchers have overcome fundamental challenges in molecular electronics, building reliable single-molecule electronic devices. Advances in fabrication and interface control enable predictable responses to light, electric fields, redox states, or mechanical forces.
Researchers developed a miniature side-viewing fiber probe that breaks the trade-off between image sharpness and depth. The probe achieves extended imaging depth while preserving high lateral resolution, enabling clinicians to see deeper without sacrificing detail.
A review decodes the comprehensive role of GDF15 in prostate cancer metabolism, chemoresistance, and clinical applications, highlighting its involvement in cachexia, bone metastasis, and drug resistance. The study also explores the synergistic power of combining GDF15 with established markers for improved diagnosis and prognosis.
Researchers at Seoul National University have developed an AI-based material redesign technology that transforms hard-to-synthesize materials into synthetically feasible forms. The SynCry model successfully redesigned over 3,400 structures, accelerating the development of next-generation semiconductor and battery materials.
A cohort study of 47,000 adults found that males had a 63% greater risk of all-cause mortality compared to females after adjusting for demographic and behavioral factors. The study suggests intrinsic biological factors, such as sex hormones or immune response, may contribute to these sex differences in mortality.