Researchers report successful xenotransplantation of genetically edited pig kidney to patient with end-stage kidney disease, achieving longest dialysis-free survival of 271 days. The study highlights the potential of xenotransplantation as a bridge to human transplant, addressing the organ shortage crisis.
Two UCLA studies published in Cell and Science uncover the role of metabolism and physical signals in guiding radial glia to produce specific cell types in the developing human cortex. Metabolic research found that the pentose phosphate pathway influences cell fate, while thalamic projections make direct physical contact with radial gl...
Researchers found that patients with lung cancer had more detectable microplastics and higher microplastic burdens in their lung wash and tissue samples. The study suggests a link between microplastics and lung disease, with polypropylene and polyethylene being the most common types of plastic.
Women with a history of gestational diabetes in pregnancy are at a substantially increased risk of developing type 2 diabetes later in life, with a median onset age 13 years earlier than those without prior gestational diabetes. They also experience more severe disease, requiring insulin treatment more frequently.
The study found that Indy gene reduction is associated with lower bacterial load and higher bacterial diversity in aging fruit flies compared to controls. Reduced Indy activity also linked to improved intestinal homeostasis, reduced oxidative stress, and maintenance of gut integrity.
Lurie Children's hospital is launching a clinical trial for a new radiation therapy that spares healthy tissue, offering hope to children with brain tumors. The trial will use a novel technology to deliver higher doses of radiation while minimizing exposure to surrounding healthy tissue.
Jack Dongarra, Yilu Liu, and Parans Paranthaman receive R&D 100 Awards for their work on innovations in large-scale computing and power grid resilience. Dongarra's team developed Fenix, an open-source software that detects and repairs hardware failures in supercomputing applications.
AI has evolved from an ambitious idea to a powerful force in science, medicine, industry, and environmental protection. Emerging co-scientist systems can generate hypotheses, evaluate ideas, and refine research directions, pointing toward a future of AI as a digital scientific collaborator.
Researchers at Drexel University's College of Medicine found a 58% greater risk of cognitive impairment or dementia in patients with voice disorders, compared to those without. Voice disorders may be an early sign of cognitive decline, challenging the traditional focus on hearing loss as the primary risk factor.
The National Academy of Inventors has launched the National Invention Ambassadors Network to inspire future generations of innovators and build America's future. The network brings together accomplished inventors from various sectors, including higher education, industry, and government, to mentor students, researchers, and entrepreneurs.
WPI researchers Fatemeh Ganji and Fanglin Che have been awarded NSF CAREER Awards to develop privacy-preserving neural networks and an AI-enabled simulation framework for electrochemical technologies. Their research will lead to breakthroughs in cybersecurity and electrochemical technologies guided by AI.
A study of nearly four million Roman coins reveals how Rome's economic integration facilitated its territorial expansion. The research, led by Eduardo Amaral Haddad and Inácio Fernandes Araújo, used digital archaeology and data science to reconstruct the monetary circulation of the Roman Republic from 155 BCE to 2 CE.
A new study found that proteins with a certain type of structure are more likely to misfold and be targeted for removal, yet nearly half still evade the cellular maintenance crew. This can disrupt protein production and recycling, potentially contributing to aging and disease.
Researchers from Texas A&M are testing far-UVC light to determine its effectiveness in reducing airborne pathogens in commercial poultry houses without harming birds. The study, led by Morgan Farnell and Ziteng Xu, aims to provide a new tool for the poultry industry to protect bird health and reduce mortality and economic losses.
Researchers have developed a fast and simple way to turn lignin, a plentiful plant-based byproduct of the paper making industry, into potentially more valuable renewable chemicals. The new method uses tiny water droplets energized by sound waves to break down Kraft lignin in just 20 minutes at room temperature.
A recent international study identifies the importance of integrating different land use initiatives, involving various social groups, and continuously refining measures to prevent wildfires. The researchers advocate a long-term, preventive approach to shaping resilient landscapes that combine ecological, economic, and social objectives.
Researchers found that students with lower grades and test scores are overrepresented in male-majority fields, while LGBTQ+ students are underrepresented. The study suggests that social norms and institutional environments may be contributing to these gaps.
A study found that bats, not bird numbers, contribute to pest control in macadamia nut production. Higher bat activity reduces insect damage and increases yields, with natural habitats playing a crucial role in supporting beneficial organisms.
Researchers have found that coastal wildflowers, such as the yellow monkeyflower, have evolved multiple adaptations to withstand salt spray, including altered pore structures and ability to bead up and roll off salt droplets. This knowledge could point to ways to make other plants, including crops, more resilient to salt exposure.
Researchers identified biomarkers of bone formation that declined with corticosteroid treatment, but recovered after transitioning to vamorolone. The study provides insights into the effects of corticosteroids on childhood growth and bone health.
Organic chemistry is challenging AI researchers to think outside the box, driving advances in how AI represents complex problems and reasons from limited evidence. This is enabling the development of more reliable, efficient, and transparent AI systems that can support various areas of science and society.
A new statewide survey in Massachusetts found strong support for expanding access to affordable plant-based proteins, with 74% backing the Bean New Deal Bill. The bill would expand access to plant-based protein options in public institutions and incorporate nutrition education related to plant-based proteins.
The INSULIN Act would cap out-of-pocket insulin costs at $35 per month for people on private insurance, establishing a resource center and hotline for uninsured individuals. The Endocrine Society applauds the bipartisan bill, which aligns with its Insulin Access and Affordability Position Statement.
Researchers uncover the broad range of diseases caused by varicella zoster virus, including neurological and systemic issues, and highlight the need for better understanding and treatment of its manifestations. The virus can reactivate years after chickenpox and affect every organ, making diagnosis and treatment challenging.
Peter Barton Hutt, a visionary leader in food and drug law, passed away on September 2, 2026. He was a co-author of the leading casebook and testified before Congress over 100 times, shaping modern regulatory science. C-Path mourns his loss and thanks him for his service to the organization and public health.
The Starr Healthspan Innovation Alliance will bridge the gap between scientific discovery and life-changing treatments for age-related diseases. The partnership will expand clinical trials and support groundbreaking laboratory research to extend healthy lifespan.
Researchers at Marshall University have identified a cellular signaling pathway in fat cells that may play a role in the development of atherosclerosis, offering a potential new target for treatment. Blocking this pathway in fat cells reduced the formation of atherosclerotic plaque and decreased inflammation in blood vessels.
A new University of Michigan study found that smartwatches can provide accurate health data, but many outputs are estimates rather than direct measurements. Users should interpret data responsibly, considering factors like watch fit, movement, and sensor accuracy.
Pet owners hospitalized often face barriers to pet care, and experts advocate for comprehensive family-centered care recognizing the human-animal bond. The human-animal bond can become even more consequential when people become seriously ill, highlighting the need for healthcare systems to address this critical relationship.
A review led by UCLA investigators found that AI can identify subtle signs of breast cancers missed during routine mammograms, but its clinical benefit is uncertain. AI may also identify patterns associated with an increased risk of cancer before it becomes visible on a mammogram.
Researchers at Goethe University are addressing pressing questions on global finance and aging processes. Dr. Johannes Petry is examining the geopolitics of global finance, while Dr. Seda Koyuncu is investigating the mechanisms underlying aging and neurodegenerative diseases.
A Simon Fraser University study found that fake clinician reviews are often seen as more trustworthy and helpful than genuine ones. Fake reviews tend to provide more detailed information about symptoms, diagnoses, and treatment, exploiting a gap between what people want to read and what they are willing to share publicly.
Research on European mountain summits reveals a rising number of plant extinctions despite increasing biodiversity, with specialists of high-elevation ecosystems primarily affected. Climate warming is driving these local extinctions, which are more likely to occur on summits with stronger warming and lower species' range margins.
Researchers discovered that psilocybin prevents nerve injury and associated symptoms in preclinical models, protecting sensory nerve endings and preserving touch sensation. Psilocybin may offer a new intervention for preventing chemotherapy-induced peripheral neuropathy, improving patients' quality of life.
Cancer cells release natural antioxidants, such as Peroxiredoxin 1, to suppress immune-cell activity and prevent destruction. Removing this antioxidant production enhances the cancer's response to immunotherapy.
The American College of Cardiology and American Heart Association have introduced a new framework, Tactical Clinical Management (TCM), to evaluate cardiovascular risk and fitness for duty in tactical athletes. This guidance addresses the unique needs of professionals working in high-risk environments, where sudden incapacitation can af...
A new study by CHOP researchers reveals that C. difficile colonization in infants can lead to a remodeling of the developing epithelium and a reshaping of the mucosal immune system, potentially increasing the risk of some viral infections in adulthood. Early life exposure to C. difficile may have profound effects on healthy development...
A comprehensive molecular study of ageing found that genetic factors and environmental influences continuously interact to shape an individual's ageing journey. Researchers identified distinct biological shifts, including correlations between environmental exposures and molecular profiles, which may indicate higher risk of disease and ...
Researchers found that psilocybin durably prevented chemotherapy-induced peripheral neuropathy in mice, preserving nerve function and tumor-killing effects. The study's findings have potential disease-modifying approaches to chronic pain and may reframe CIPN as a failure of resilience that can be addressed with early intervention.
Climate warming causes mountain plants to shift their ranges, leading to increased local extinctions among specialized high-elevation species. Declines in plant abundance often precede local extinctions, suggesting shrinking plant cover as an early warning sign.
An eight-year study of 335 women reveals individual molecular trajectories of aging diverge from population-wide patterns, influenced by genetics and environmental exposures. The study found over 5,000 genes and 181 metabolites changed over time, including those associated with age-related diseases.
A climate coalition adopting carbon pricing for heavy industries could reduce global greenhouse-gas emissions by 1.5% while generating $200 billion in annual revenue. The approach also limits carbon leakage and builds on existing policies, offering a practical pathway to overcome international climate-policy coordination problems.
Researchers developed a composite material with three-dimensional nano-interfaces, enabling thermoelectric conversion in a macroscale material. The spin Seebeck effect was successfully observed in an insulator, providing a new material design paradigm for thermal energy utilization.
The BESIII Collaboration has achieved the world's most precise measurement of the Lambda hyperon electric dipole moment using quantum-entangled Lambda-anti-Lambda pairs. The result improves experimental sensitivity by three orders of magnitude, providing a new way to probe charge-parity violation in particles containing strange quarks.
Researchers at Stanford University have developed a highly efficient method for producing sustainable hydrogen, drastically reducing CO2 emissions. The new process, called methane pyrolysis, produces mostly water and high-quality graphite, a valuable byproduct with potential applications in battery materials and other technologies.
Researchers discovered that cancer cells use an antioxidant protein to suppress T cells, allowing them to evade the immune system. This finding identifies a promising new target for cancer immunotherapy, potentially helping to overcome treatment resistance and improve patient outcomes.
A Stanford-led team created a quantum-optical spin glass to increase AI memory capacity. The network, called a quantum-optical spin glass, has a greater capacity to hold and recall memories than traditional AI networks, exhibiting short-term plasticity similar to the brain's synaptic connections.
Researchers found that betalain pigment in beets is linked to drought tolerance in flowering plants, enabling the evolution of succulent traits. The pigment's role in water storage and metabolic processes was also explored.
Researchers found that composite metal foam (CMF) can absorb more energy during high-velocity impacts, reducing crash severity and improving driver and passenger safety. CMF outperformed conventional front rail designs, increasing safety limits by up to 40% and reducing maximum deceleration by 38%.
The ACC Quality Summit 2026 aims to drive meaningful change in cardiovascular care through the sharing of innovative solutions and real-world successes. Key takeaways from the summit will focus on improving patient outcomes, enhancing patient experiences, and driving lasting change in the healthcare system.
The 12 companies selected will work alongside Mayo Clinic Platform's experts and leverage its de-identified clinical data ecosystem to advance digital health solution development. The program aims to transform healthcare through AI-enabled solutions leveraging clinical data and advanced analytics.
Dr. Fabian Voigt establishes a new research group at MPZPM to develop optical microscopes for brain research and investigate animal spatial orientation and cognitive mapping. The group aims to overcome the limitation of optical microscopes being unable to capture brain activity in freely moving animals.
Andrea Iannelli's ERC Starting Grant project aims to develop adaptive autonomous systems that learn, adapt, and act in complex environments. The project proposes a new framework combining control theory, optimization, and statistical learning to achieve safe and robust behavior.
Scientists at Virginia Tech have designed two types of degradable adhesives: one made from lipoic acid that outperforms duct tape, and another with a bottlebrush polymer that is four times stronger. Both can be broken down into their original components within minutes, making them ideal for recyclable applications.
A new Drexel-led study introduces a culinary medicine program for caregivers of children with cancer, which improves nutrition and overall well-being. The program combines live virtual culinary workshops and individualized coaching to help families address treatment-related nutrition challenges.
Researchers developed a bio-based Fe-MOF nanoreactor that combines natural-ligand chemistry with multimetallic redox catalysis, biomimetic targeting and MRI visibility. The nanoplatform produced a strong ROS response, increased apoptosis, and tumor inhibition in breast cancer cells and mice.
Parth Pathak from George Mason University aims to create an AI-assisted cross-layer timing anomaly detection framework to secure data center timing infrastructure. The project received $100,000 in funding from the Virginia Innovation Partnership Authority.
A new research centre, InnoHK I-GET, will use AI and data analysis to make smart grids more efficient and resilient in Hong Kong and globally. The centre will bring together leading academics and industry partners to develop a future power grid capable of supporting electric vehicles and AI-enabled services.
Drexel researchers found converging evidence for three mechanisms that contribute to music-based interventions' effectiveness, including selecting personal music and engaging with it. The study emphasizes the need for more research into music's effects on pain, particularly in individuals with chronic pain.
A new review finds that the body actively adapts to sustained plant-based diets, absorbing iron more efficiently, synthesizing creatine and carnosine, and remodeling gut bacteria to better ferment fiber. This adaptation, not just intake numbers, determines long-term nutritional status.