A new study from the University of Pennsylvania School of Nursing's Center for Health Outcomes and Policy Research found that nurses' assessments of their staffing adequacy is a more accurate predictor of patient safety on medical surgical units than traditional administrative data. In contrast, objective metrics like RNHPPD proved to ...
The program achieved a definitive genetic diagnosis in nearly half of enrolled children, identifying pathogenic variants across 330 genes. Families received timely diagnoses, allowing accurate genetic counseling and informed reproductive choices, while guiding clinical management and opening access to targeted therapies.
Scientists have traced the origin of massive Atlantic Sargassum blooms to coastal waters near the Gulf of Guinea in West Africa. The study uses physics-based modeling and probabilistic analysis to show that blooms can be tracked back up to two years before they are detected by satellites.
A team at Virginia Tech developed a water-based process to create multilayer bioplastic films that are both high-performing and easier to manufacture. The method avoids toxic solvents and matches current industrial production speeds, making it viable for real-world use.
DraftMarks makes the writing process visible by layering visual cues to indicate AI involvement. The tool helps writers confront their collaboration with AI and make intentional judgment calls.
The Alliance for Clinical Trials in Oncology has several active trials specifically designed to help people with head and neck cancers. Trials include testing high-dose prophylactic gabapentin to prevent opioid use during treatment, as well as immunotherapy with nivolumab and cabozantinib for mucosal melanoma and nasopharyngeal carcino...
A new trial found that proximal hypoglossal nerve stimulation (pHGNS) significantly reduced breathing interruptions during sleep and improved daytime sleepiness without adverse events. The therapy, an FDA-approved alternative to nasal positive airway pressure, was found to be safe and effective in patients with moderate-to-severe obstr...
A phase 2 trial found that all patients with high-risk smoldering multiple myeloma became MRD-negative within two months of CAR T-cell therapy, with sustained MRD-negativity at a median follow-up of 15.3 months. No severe side effects were observed.
Georgia Tech researchers used computer models to reveal how cells physically pull the neural tube closed during early development. The study found that forces generated by cells create a 'purse string' mechanism made of actin, which tightens and draws the tube closed through a synchronized pattern of cell movement.
Researchers found that Tennessee wine buyers are willing to pay more for wines featuring the state's Quality Assurance Program (QAP) label and those sourced from American Viticultural Areas (AVAs). Consumers also prefer higher-alcohol content wines. The study aims to improve the quality of Tennessee wines and promote the industry.
The partnership aims to align payers and providers around a core set of behavioral health quality measures, creating a shared foundation for how care is delivered, evaluated, and improved. NCQA and West Health will test and refine quality measures across diverse care settings and payer environments.
A new three-step synthesis strategy enables simultaneous control over composition and surface facets of high-entropy alloy nanoparticles. Researchers have scaled the process to produce millions of particles across unique compositions, opening a path to discovering next-generation HEA catalysts with high-index facets.
A new study suggests that a low dose of ibuprofen can help alleviate chemo-brain symptoms in cancer patients, but exercise remains the most beneficial intervention. Researchers randomized 86 patients to receive either exercise plus ibuprofen or other treatments and found that exercise significantly improved cognitive function.
Researchers measured mitochondrial function using MRI in 11 cancer survivors, finding slower recovery time signals weaker function, but also a surprising correlation between worse mitochondrial recovery and lower fatigue. The study suggests that subjective experience of fatigue is multidimensional and not solely physical.
Researchers at Cornell University developed a soft robot gripper that can detect the ripeness of strawberries by touch, then gently twist them off their branch or vine. The technology has potential for more resilient and ecological food production.
A new study found that every type of epigenome protein produces a distinct pattern of gene expression, surpassing the on/off switch functionality. This discovery has significant implications for cellular engineering, enabling more dynamic control over cellular behavior and potential applications in biomanufacturing and bioproduction.
Researchers at University of Michigan created a stem cell model that produces a yolk-sac-like structure in a human embryo, mimicking early pregnancy loss. The model uses mechanical signals to guide development and does not require genetic manipulation.
Researchers show math underlying quantum gravity bears resemblance to quantum Hall effect, resolving cosmological constant problem. The Chern-Simons-Kodama state, a proposed ground state of quantum gravity, has a similar topology that keeps the cosmological constant's value stable.
A new study published in the Proceedings of the National Academy of Sciences found a link between elevated serotonin levels and tinnitus behavioral symptoms. The research suggests that clinicians should recognize and validate patient reports of medication-associated increases in tinnitus when prescribing antidepressants like SSRIs.
A new study found that pediatric patients with long-COVID experience a high symptom burden, including sleep disturbance, anxiety, depression, and fatigue. The study describes an interdisciplinary care approach that incorporates integrative medicine, nutrition, and lifestyle modifications to manage symptoms.
The Universitat Jaume I and AICE have established a joint GEA research laboratory to promote joint research and innovation in environmental engineering. The lab aims to foster knowledge transfer, train PhD graduates, and collaborate with companies in the region.
An international research team at the Mainz Microtron MAMI achieved the most precise measurement of hypertriton binding energy to date, revealing it is significantly more strongly bound than earlier experiments suggested. This breakthrough provides new insights into the interaction between hyperons and nucleons.
A global study has developed 15 internationally comparable indicators for climate communication and education, addressing the lack of reliable data on these essential actions. The indicators cover multiple dimensions of climate change mitigation and adaptation efforts.
Researchers from ICTER and the FDA Center for Devices and Radiological Health developed a new method to visualize the entire retina without refocusing. This breakthrough uses adaptive optics optical coherence tomography (AO-OCT) to generate three-dimensional retinal images with cellular resolution.
Researchers have developed a unified mathematical model explaining two types of 'breathing' solitons in ultrafast lasers, overcoming decades-old puzzle. The new framework accurately predicts complex behaviors and reveals underlying mechanisms.
Scientists discovered that deep-water coral ecosystems in the Galápagos region vanished for over 1,000 years due to prolonged La Niña-like conditions. The study found that these ecosystems may be more susceptible to climate change than previously thought, with significant implications for conservation efforts.
A study by the CNIO group has identified a genetic signature in precancerous breast lesions that can predict which ones will evolve into invasive tumours. This discovery could help avoid over-treatment of women diagnosed with ductal carcinoma in situ, a common precancerous lesion.
The discovery of seven millimeter-sized phosphatized fossils from the early Fortunian Kuanchuanpu Formation provides evidence of annelid body fossils from Cambrian Orsten-type fossil localities. The findings suggest that early annelids were polychaetes, supporting the hypothesis that polychaete morphologies were primitive among annelids.
Researchers developed a machine-learning model to predict protease behavior, enabling more precise and effective treatments. The ProSSpeC calculator suggests engineered synthetic proteases that outperform widely used enzymes.
Researchers found that connected natural habitats help maintain beneficial skin microbes that inhibit deadly fungal pathogens in tropical amphibians. Habitat fragmentation weakens these microbial defenses, leading to increased pathogen infection levels.
Dr. Stuart Orkin has been awarded the Breakthrough Prize in Life Sciences for discovering genetic mechanisms underlying hemoglobin production and developing a therapy using CRISPR/Cas9 technology. The therapy, Casgevy, treats patients with sickle-cell anemia and beta-thalassemia, debilitating blood disorders affecting millions worldwide.
A new review highlights the role of intestinal stem cells (ISCs) and their supportive microenvironment in driving colorectal cancer initiation, therapy resistance, and relapse. Targeting the ISC–cancer stem cell ecosystem offers a promising strategy to develop next-generation precision care for patients.
A new study uses CRISPR technology to edit grapevine DNA, reducing vulnerability to downy mildew while improving water conservation. This breakthrough could lead to climate-resilient crops in Africa, addressing growing challenges in viticulture.
A new study reveals a significant link between obstructive sleep apnea and skeletal muscle quality, indicating an increased risk of muscle deterioration with aging. Researchers found that people with obstructive sleep apnea have lower skeletal muscle density and a higher skeletal muscle index than those without the condition.
The KIR-CAR T cell therapy has shown promising results in a Phase I clinical trial, demonstrating safety and increasing efficacy with higher doses. The treatment targets mesothelin, widely expressed on several solid tumor cancers, and limits side effects through its natural 'on-off' mechanism.
Researchers at TU Wien found that 2D materials are unsuitable for smaller electronic structures due to a tiny gap formed between the material and insulating layer. However, some materials can be combined with stronger bonds to eliminate this issue, potentially revolutionizing miniaturization steps.
Researchers tracked 30 patients with chronic blood cancers over time, finding that those whose disease remained stable had 'steady' blood cells without additional mutations. Conversely, those with progressing diseases developed changes in DNA years before symptoms worsened. This challenges current views on diagnosing patients without t...
The Helmholtz Association has launched a Water Safety and Security Campaign to protect human health and the environment. Two projects, URBAN-LE Solution Lab in Leipzig and SOLVE initiative in the Elbe River basin, focus on urban resilience and river ecosystem recovery through integrated approaches.
Researchers create molecular crystal with reversible color changes spanning from green to orange-red upon mechanical stress or pressure. The material exhibits adaptive intermolecular interactions and structural flexibility, enabling stimulus-responsive luminescence.
This review highlights the key findings of laser additive manufacturing of metallic lattice structures, including TPMS architectures, node reinforcement, and machine learning-driven optimization. The study demonstrates enhanced mechanical performance, energy absorption, and multifunctional capabilities such as thermal management and vi...
Compass combines Dimensions citation data and Altmetric attention metrics in a single platform, providing real-time publication intelligence. This solution addresses the fragmented data challenge faced by medical affairs teams, enabling them to make informed strategic decisions and communicate impact more effectively.
The report highlights rapid growth of solid-state implementation since SKKU's first successful realization in 2012, with China, US, and South Korea leading global research efforts. Sungkyunkwan University demonstrates world-class research competitiveness, ranking highly in key indicators.
A new AI framework combines digital pathology and structured clinical data to predict PIK3CA mutation status in breast cancer. The Multimodal PIK3CA Model outperformed single-modality models, achieving an AUC of 0.745, with strong performance across multiple clinical datasets.
Elif and Alp Tural teach interior designers to consider how spaces affect users every day, emphasizing trauma-informed design and visual accessibility. Their approach aims to create legible and comfortable environments that respond to users' needs.
Researchers discovered that HDAC7 plays a dual role in immune system development and cancer progression. Restoring HDAC7 in cancer cells can slow or stop tumor growth, offering new hope for diagnosis and treatment.
Researchers develop signal-processing method to suppress distortions, achieving 6mm spatial resolution in single-ended Brillouin sensing. This enables early detection of damage or abnormal conditions in aging infrastructure.
Researchers have identified a new geometric marker of the brain ventricles that can predict which patients with idiopathic normal pressure hydrocephalus (iNPH) will benefit from shunt surgery. The study found that a specific geometric feature, asphericity, is strongly associated with better surgical outcomes.
The Nordic Seas Overturning Circulation (NOC) has strengthened while the Atlantic Meridional Overturning Circulation (AMOC) has weakened due to global warming. Models project a slight increase in NOC's density-driven mechanism, which counterintuitively strengthens the northern branch despite AMOC weakening.
Dr. Eric Richards, a professor at BTI, has been awarded a 2026 Guggenheim Fellowship to investigate Daniel MacDougal's pioneering work on ovarial injection experiments in plant genetics. He aims to use archival research and modern DNA sequencing to determine if MacDougal's protocol actually created mutations.
Children who survive severe childhood malaria experience cognitive and academic impairment that persists into adolescence. The correlation highlights the urgent need for better prevention strategies and therapies to minimize lasting effects of the disease.
Astronauts experience difficulty transitioning between Earth and space due to brain predictions about gravity's pull. After prolonged periods in weightlessness, they overcompensate with their hand grip when returning to Earth, but gradually adjust over time.
Researchers at Hokkaido University developed a new method to measure small forces with high precision, discovering light can twist tiny objects sideways. This phenomenon depends on optical helicity, a subtle property of the light's electromagnetic field.
Researchers at NUS have developed a paired protein language model (PPLM) to predict protein interactions, improving accuracy by up to 17% over leading methods. The model has strong performance across multiple tasks and can capture biologically meaningful relationships between proteins.
Researchers review advanced AI algorithms and hardware acceleration techniques to predict material properties, optimize structures, and discover new materials. This review provides crucial guidance for accelerating data-driven materials research and fostering next-generation functional materials development.
Researchers at the University of Houston found that distraction disrupts memory consolidation primarily due to demands on central executive processing. To improve short-term memory, focus attention on a task for a few seconds before switching, and avoid multitasking.
Researchers at Saarland University have developed energy-efficient geometries for elastocaloric cooling elements using 3D printing. The technology uses shape-memory alloys to release heat when stretched and absorb it when released, promising a cleaner alternative to traditional cooling methods.
The American Geriatrics Society has honored 18 leaders in the field of geriatric medicine for their outstanding contributions to high-quality, person-centered care for older adults. These awards recognize individuals who have made significant impacts through education, research, and clinical practice.
Researchers at Ehime University discovered a π-stacked dimer of positively charged antiaromatic molecules stabilized upon stacking, contrary to their inherent instability. The findings suggest that intermolecular stacking can partially attenuate the intrinsic instability characteristic of antiaromatic molecules.
Professors José María Martín-Olalla and Jorge Mira Pérez refute the 2025 study linking Daylight Saving Time to negative health outcomes, citing a critical error in methodology. The original study's conclusions were based on an incorrect calculation of daily readjustments, which resulted in a zero annual cumulative total.
Scientists have demonstrated a reconfigurable photonic circuit implementing wide class of complex unitary transformations via optical manipulation at three layers only. The platform enables flexible access to many co-propagating structured modes, making it suitable for applications in communication, information processing, and simulation.