Researchers at the University of California San Diego used computational models and virtual reality to study the social interaction rules of schooling fish. They found that individual fish 'copy' the movement direction of a randomly-chosen nearby neighbor, leading to highly dynamic behavior in groups.
Researchers have identified a hidden defect in the gut that can damage intestinal cells, even in patients with well-controlled disease. The study found that this defect can be present in patients with clinically mild disease and can lead to future flares.
A multicenter study found that early rasburicase treatment can significantly reduce the risk of dialysis and death in adults with tumor lysis syndrome. The study analyzed data from 1,276 patients and showed that early rasburicase treatment was associated with lower 90-day mortality and faster return to cancer therapy.
Researchers at Columbia University have discovered a new type of cell that protects lung cancers from attacks by the immune system. The new cells, called CHL1 fibroblasts, promote lung cancer by recruiting regulatory T cells to the border of the tumor.
A new study found that US adults' interpretation of 'plant-based' diet differs significantly by age, with older adults equating it to veganism. The study, published in the American Journal of Lifestyle Medicine, analyzed data from 2,202 US adults and found that younger adults (18-34 years old) have a more nuanced understanding of the t...
A study found that 65% of young children brought to ERs for suspected poisoning didn't need emergency care, and could have stayed home with a phone call to the poison center. This could save millions of dollars nationally each year, as routing avoidable cases to the phone line could save $1,000 per visit.
This review synthesizes clinical and basic research progress on obesity and CVDs, exploring epidemiology, pathophysiology, and management strategies. The authors highlight the effects of obesity on various CVDs, emphasizing the need for effective prevention and treatment strategies.
A new study reveals that Parkinson's disease costs Europe €22.8 billion annually, with direct medical and non-medical costs, informal care, and lost productivity contributing to the total burden. The condition's prevalence in Europe has nearly doubled since 1990, with Germany recording the highest national costs at €5.7 billion.
A University of East Anglia report suggests that tens of thousands of new mothers in Britain may be suffering from undiagnosed PTSD after childbirth. The report highlights the need for better guidance and training for GPs to identify post-traumatic stress disorder symptoms.
A new study found that El Niño events have become nearly 40% stronger in the last 40 years than they were in the pre-industrial era. The researchers used coral reconstructions from the Galápagos Islands to examine historic El Niño patterns and confirm that the current El Niño event is superimposed on global warming, likely to superchar...
The DSTOX platform uses a multi-strategy fusion approach to integrate statistical rule-based models, expert knowledge rule-based models, and analogue search for mutagenicity assessment. The platform achieved an accuracy of 92.0% in internal validation and 84.0% in external validation, comparable to mainstream prediction tools.
A new clinical trial initiative aims to determine the best treatment strategies for older adults with acute myeloid leukemia, a life-threatening blood cancer. The five-year trial, led by Fred Hutch Cancer Center, will compare stem cell transplantation with non-transplant therapy for patients in remission.
SUNY Chancellor King visited the Great New York State Fair, showcasing participating SUNY campuses and offering free admission to current and incoming students. The event highlights SUNY's agricultural, healthcare, and technology initiatives.
Researchers discover a natural compound ascr#18 that primes plants to fight pathogens more effectively, increasing resistance without sacrificing growth and development. The treatment, effective in various crops, provides a promising solution for global food security and sustainability.
The Railway and Infrastructure Laboratory (RaIL) at Graz University of Technology allows for realistic testing of complete track systems, investigating load-bearing capacity and durability. This enables research into track structure interactions and the effects of environmental conditions on durability.
Scientists have developed a new acoustic levitation technique using an ultrasonic beam capable of levitating and moving small objects in mid-air over distances of up to 40cm. The technique, which uses a zero-order Bessel beam, enables stable levitation six times further than previously achieved using conventional methods.
Joachim Groß, a process engineer, has received an ERC Advanced Grant to develop an open-source system that combines empirical and physical models for predicting complex chemical processes. The system aims to overcome the limitations of current models and provide a high degree of precision for both science and industry.
Numerical experiments show that parameterization of orographic gravity wave drag reduces rainfall intensity overestimation and improves forecast accuracy. The study suggests current OGWD parameterization schemes require further improvements to achieve greater forecasting accuracy.
A Peking University team developed a homogenized gridded climate dataset for China, removing non-climatic signals from traditional meteorological observations. The dataset helps detect and attribute climate change, overcoming difficulties in correcting gradual and abrupt inhomogeneities.
A new study reveals a 3,307% increase in recreational drug ingestions among young children from 2000 to 2024, with most ingestions involving cannabinoids. The ingestion rate of marijuana edibles increased by 2,349% from 2015 to 2024, driven by the rapid growth of marijuana edibles and state legalization of cannabis.
A new study from the University of East Anglia found that people who swim in rivers and lakes are more than twice as likely to develop skin problems. Higher levels of bacteria linked to faecal pollution are also associated with an increased risk of stomach bugs. The study, which analyzed data from 2,368 volunteers, found that swimmers ...
University Hospitals has received American Heart Association Get With The Guidelines - Stroke awards for its commitment to ensuring timely, appropriate treatment for stroke patients. The hospital has achieved high levels of quality care, including door-to-needle times of 45 minutes or less for 75% of patients.
Researchers found that personalized content from social media algorithms can negatively impact users' mental health by reinforcing negative emotions and thoughts. The study suggests that educating people on critical social media engagement behaviors can help mitigate this effect.
A new study found that a more diverse plant-based diet is associated with lower BMI, higher HDL cholesterol, and better overall diet quality. Consuming a wider variety of plants per week was linked to improved gut microbiome scores and higher fibre intake.
A study by Yale University ecologists found that 16% of Mexico's habitat is covered by protected areas, but overlaps increase when including wildlife management units and Indigenous territories. The analysis highlights the need for a diverse mosaic of conservation areas to protect carnivores, with priority areas identified for expansion.
A new study reveals that pre-cancerous blood cells can actively reshape the bone marrow environment, creating conditions that favor their growth and increasing the risk of blood cancer. By targeting the aging bone marrow environment, scientists may be able to slow down or prevent blood cancers before they arise.
NY Creates will receive $1.25 million to support research, technology scaling, and workforce development in quantum computing. The institute aims to overcome significant barriers to practical quantum computing by developing techniques for fabricating hardware and education programs.
The partnership aims to advance additive manufacturing for critical energy challenges, including nuclear energy and broader energy infrastructure. SRNL and 3D Systems will jointly pursue advancements in materials development, equipment enhancements, and workforce development training.
Corals hosting heat-tolerant algae are more resistant to heat stress, but their immune systems are suppressed, making them more prone to disease. This trade-off helps explain why some corals appear more resilient but struggle to survive in complex environments.
A new clinical decision support tool, FRACTURE-ML, identifies people at high hip fracture risk using existing health registers and avoids patient-reported information. It has the potential to become an important tool for preventive care, potentially identifying nearly seven times as many people at risk of hip fracture.
New research explores monarch butterfly conservation in rangelands and the effectiveness of state regulations for controlling invasive species. Studies reveal that ungrazed pastures support more milkweed and monarch eggs than grazed sites, highlighting the need for selective approaches to conservation.
Researchers at CU Anschutz and Indiana University School of Medicine identified a biological process that explains how colorectal cancer can cause severe muscle and bone loss. Blocking the production of a protein called IGFBP1 helped preserve muscle and bone, improving muscle strength in laboratory and preclinical models.
Researchers at the University of Michigan found that older adults who experienced food insecurity in both midlife and later life had nearly four times the risk of probable dementia. Food insecurity was concentrated among those who experienced it later in life, rather than midlife alone, suggesting a strong association between later-lif...
Researchers created a self-stratified stretchable passive cooling interface that reduces temperature in wearable electronics. The interface, composed of aluminum-oxide-rich and liquid-metal-rich layers, combines external-blocking and internal-dissipation functions, improving cooling performance.
Pinoresinol diglucoside (PDG) attenuates diabetic cardiomyopathy by suppressing store-operated calcium entry and downregulating STIM1/Orai1/NFAT3 signaling pathway, ultimately inhibiting the progression of diabetic cardiomyopathy.
Quzhou Fructus Aurantii ethyl acetate extract (QFAEE) significantly ameliorates liver enlargement, lipid accumulation, and liver injury in MASH models. It activates the PPARalpha signaling pathway, upregulating CPT1A and downregulating lipogenic markers.
Researchers found that using the loose side of thin wood sheets as the tension surface reduces stress concentration and improves bending performance. This technique resulted in significant cost savings and waste reduction, making it an attractive alternative to traditional reinforcement methods.
A 2-year multicenter cohort study found that most hospitalized survivors maintained or regained cognitive function after Omicron infection, while older and reinfected patients may face progressive decline. The study identified age, infection history, and disease severity as risk factors for progressive decline.
Researchers developed a method to enrich EVs from whole blood, capturing complementary biological information lost in plasma or serum analysis. This approach may support deeper investigation of disease mechanisms and discovery of circulating biomarkers.
UM171 molecule helps retain stem cell properties, stimulating multiplication, and exploits protein KBTBD4 to break down important protein structure CoREST. This mechanism is also affected by mutations in KBTBD4 gene, linked to aggressive brain tumours in children.
MDS26 focuses on high-dimensional data analysis, scalability, and parallel algorithms, highlighting advances in mathematical and computational methods. Researchers and practitioners will engage with emerging ideas, share insights, and define the next generation of mathematics for data science.
Researchers demonstrate optical Magnus effect in trapped calcium ion, affecting laser control in quantum computers, with potential for complex computations and precise qubit coupling. The effect's magnitude depends solely on the wavelength of the light, not the laser's focus.
Researchers at Boston Medical Center and Boston University have developed a scalable method for generating CD4+ helper T cells from induced pluripotent stem cells (iPSCs), overcoming a longstanding challenge in the development of stem cell-based immunotherapies. This breakthrough could help advance efforts to create off-the-shelf CAR-T...
Researchers at MIT developed bifur-circuits, a new type of shape-changing smart device that can be reconfigured to form different shapes and maintain electrical connections. These interactive building blocks can be used to create adaptable smart devices, such as assistive furniture and reconfigurable robotic grippers.
Mayo Clinic joins a consortium to develop affordable, scalable gene-editing therapies for children with rare inherited immune disorders. Researchers will use CRISPR-based technologies to repair disease-causing errors in blood-forming stem cells.
A new UC Irvine study suggests that social media posts can reveal where Californians may be most vulnerable to extreme heat. Researchers analyzed 24,598 heat-related posts on Twitter, finding correlations between housing, transportation, and life impacts on the effects of heat.
The conference focuses on mathematical issues in imaging, expanding its reach in science and medicine. Challenges span multiple disciplines, including physics, engineering, mathematics, and data science.
Scientists at UCSF QBI mapped 1,800 protein interactions across 100 autism risk genes, revealing how diverse genetic mutations converge on shared molecular pathways. The study provides a framework for designing medicines that target multiple genetic forms of autism simultaneously, offering advantages in brain delivery and tolerability.
Researchers found that theta oscillations during learning predicted which experiences were remembered after sleep, and this pattern was associated with better memory performance. The study suggests that the brain may use theta oscillations to 'tag' experiences for later memory consolidation during sleep.
Researchers at the University of Toronto have developed a next-generation RNA therapeutic approach that can treat a wide range of genetic diseases by helping cells read through premature stop signals. The approach, centered on transfer RNA, has shown promise in laboratory and preclinical models of cystic fibrosis, and may be combined w...
A machine-learning tool built from Swedish national health registry data can predict hip fracture risk with high accuracy and identify individuals at high risk without in-person assessment. The tool performed nearly seven times better than current screening methods in identifying at-risk individuals.
A University of Michigan study found that El Niño events have become nearly 40% stronger in the last 40 years than in the pre-industrial era. The study, which examined modern and ancient corals in the Galápagos Islands, found that El Niño events in the last four decades were stronger than any in the 1,000 years prior to about 1850.
Researchers analyzed 22 gecko species to track sex chromosome origins in real time, revealing a 'sex chromosome birth pulse' linked to climate disruption. Geckos' diverse sex chromosomes are influenced by climate, genomic predisposition, and selective pressure.
The grant will support QBI's role in ARIA's Protein-Protein Interactions Hub, mapping disrupted protein complexes and developing mechanism-based small molecule medicines. The work aims to move from fundamental science to therapeutic discovery for people with autism and others on the spectrum.
The 2026 vehicle emissions standard rollback is founded on faulty assumptions, according to a recent study. The analysis hinges on incorrect valuation of fuel savings, which results in billions of dollars in benefits being removed from vehicle emissions standards. A new framework for translating consumer behavior into cost-benefit anal...
Researchers found that 92% of magnitude-3-or-greater injection-induced earthquakes were preceded by detectable foreshocks. Foreshock productivity and patterns reflect the interplay between fluid injection, seismogenic index, and fault stress state.
A new therapy using chemically enhanced suppressor tRNAs and lung-targeted delivery restores CFTR protein production and function in models of cystic fibrosis. The approach overcomes challenges of inefficient readthrough and immunogenicity, offering a promising treatment for the genetic disorder.
A 1,000-year record from Galápagos corals shows El Niño is intensifying due to climate change, with ENSO variability 37% higher than during the preindustrial era. This increase in El Niño events poses growing risks to ecosystems, infrastructure, and human societies.
Researchers at the University of York have uncovered the neural mechanism that instructs the brain to prioritize and strengthen important memories during sleep. This 'tagging' mechanism, linked to a specific brainwave pattern, helps the brain filter out irrelevant details and retain key experiences.
Researchers discovered that SGLT2 inhibitors activate PANK1, a key enzyme that boosts energy production and improves heart function in heart failure patients. Increasing CoA production improved the ability of human heart cells to contract and relax, two critical functions impaired in heart failure.