Researchers developed a novel approach to estimate the state of health of bipolar lead-acid batteries using partial charging profiles and a hybrid regression framework. The method achieved accurate results, with an average root mean squared error below 1.5%, outperforming other models.
The webinar highlighted the potential of combining NFI field data, EO disturbance products, and national statistics for robust forest carbon monitoring. Continental-scale carbon balance analysis showed a trend towards neutral over the past decade, with large interannual variability.
ISM6200 is a potent, potentially best-in-class preclinical candidate targeting NR3C1 for the treatment of ovarian cancer, Hypercortisolism (Cushing’s Syndrome), and other disorders related to excess cortisol. The molecule demonstrates low DDI risks and higher in vivo efficacy across multiple animal models.
A new 23andMe study reveals genetic predictors for GLP-1 weight loss efficacy and side effects, providing a personalized approach to obesity treatment. The findings identify specific genetic variants associated with increased weight loss efficacy and nausea/vomiting side effects.
Researchers uncover 289 million-year-old mummy of lizard-like creature Captorhinus aguti, preserving skin, cartilage, and protein remnants. The find reveals the oldest example of costal breathing system in amniotes, shedding light on early reptile evolution.
A study comparing two blood purification strategies for septic shock found that both CytoSorbⓇ and oXirisⓇ improved hemodynamic status by reducing lactate levels and vasopressor requirements. However, no significant differences were found in primary outcomes, suggesting comparable clinical benefits.
A new study confirms a direct link between good physical fitness and reduced risk of suffering from over 30 diseases. Individuals with high genetic predisposition to be physically fit exhibit lower risks of cardiovascular conditions, diabetes, and asthma, while also showing better health in metabolic and inflammatory aspects.
Long-term opioid therapy prescription rates declined in the US from 2015 to 2023, despite a growing population of older adults receiving these treatments. Approximately 4-5 million patients were prescribed long-term opioids in 2023, with Medicare covering a larger proportion, raising concerns about safety.
A multinational study of five psychedelic compounds has identified two consistent neural effects across different drugs, weakening internal brain networks and increasing communication between networks. This breakthrough could help guide the design of future treatments for mental health disorders.
Researchers isolated intact nanoparticles from boiled Pueraria lobata and found they modulated intestinal microbiota, reducing inflammation and repairing mucosal barriers. GGD-PDVLNs administered alone replicated therapeutic benefits of GeGen decoction, highlighting their role as core active ingredients.
A new soft multiaxial strain mapping interface combines with AI processing to capture complex throat muscle movements and decode silent speech. The system achieved 85.8% recognition accuracy for NATO phonetic words in controlled tests and real-world noisy environments.
The Finnish Institute for Health and Welfare is launching a century-long research initiative to understand the roots of mental health challenges, loneliness, and social uncertainty. The study, Future Finland, will follow 200,000 families over time, examining how biological, behavioral, and social factors influence wellbeing.
Researchers predict that glaciers in High Mountain Asia may threaten future water security due to rapid melting caused by warming temperatures. The study found significant losses in glacier mass between 2002 and 2023, which could intensify short-term flood risks and reduce long-term meltwater availability.
A research team from Tokyo University of Agriculture and Technology has developed a new type of photodetector that achieves impressive responsivity and detectivity. The device uses highly ordered superlattices to overcome the limitations of traditional quantum dot-based photodetectors.
Researchers mapped the maternal-fetal interface in unprecedented detail, identifying new cell types and insights into conditions such as preeclampsia and preterm birth. The study found a previously unknown cell type that responds to cannabis, which may explain its association with poorer pregnancy outcomes.
A team of researchers at ETH Zurich has successfully realised a high-quality swap gate using only geometric phases with extremely cold potassium atoms. This breakthrough enables the robust exchange of quantum states between qubits, a crucial step towards building large-scale quantum computers.
Researchers propose tailored approaches using CAR platforms, incorporating effector cells like macrophages and Tregs to modulate key processes in neurodegeneration. High-precision immunomodulation is essential for overcoming the complex nature of these diseases.
A global inventory reveals that bottom trawling catches over 3,000 fish species, including critically endangered and vulnerable species, highlighting the urgent need for better documentation and management of its impacts on marine biodiversity.
A recent study published in Neuron provides new insight into how tau tangles spread from one brain region to another in people with Alzheimer's disease. Researchers found that tau seeds travel along individual's natural communication pathways, influencing the spread of Alzheimer's pathology and suggesting a potential therapeutic target.
A team of researchers at Kyoto University found that predatory mites avoid laying eggs on plant leaves bearing traces of caterpillars. Additionally, they discovered that even when predators are unlikely to encounter caterpillars, they still avoid their traces.
Researchers developed a quasi-dynamic mathematical model to optimize Thermally Integrated Carnot Batteries (TI-CB) under fluctuating conditions typical of factory environments. The study yielded crucial insights, including a clear roadmap for handling off-design fluctuations, bringing Carnot batteries closer to widespread deployment.
A cohort study found that individuals diagnosed with ADHD at a younger age tended to perform better academically, receiving more education and experiencing lower dropout rates compared to those diagnosed closer to age 16. This suggests that targeted support for early diagnoses could help prevent school dropout.
Researchers developed a lightweight lattice structure inspired by butterfly wings, exhibiting enhanced mechanical strength, impact resistance, and energy absorption capabilities. The new design outperforms conventional lattice designs under compression and dynamic impact loading.
A large U.S. study found that adults who never married have substantially higher rates of developing cancer compared to those who are or have been married. The association is strongest for cancers related to infection, smoking, and alcohol use, with women facing a significantly higher risk than men.
The American Society of Hematology and the International Society on Thrombosis and Haemostasis have released comprehensive guidelines for anticoagulant prophylaxis in non-cardiac pediatric patients at risk of venous thromboembolism. The guidelines outline best practices for preventing life-threatening complications in children.
RST2G automates tumor segmentation, reducing radiologist workload and improving accuracy. It captures complex tumor morphologies and boundaries, outperforming traditional methods in visual assessments.
Researchers tracked the impact of beach nourishment on nearshore conditions and marine life, finding that prolonged turbidity can interfere with blacktip shark hunting and increase accidental encounters. The study highlights a delicate balance between coastal engineering projects and marine ecosystem protection.
The Society for Cardiovascular Angiography & Interventions and Canadian Association of Interventional Cardiology will host a joint conference featuring the latest clinical data, procedural guidance, and advanced expertise. The event aims to empower clinicians with rigorous data, practical education, and leadership development.
A UCLA-led study found that unionization leads to lower turnover rates among direct care workers, with significant benefits including improved care quality and reduced stress. Unionization applies to both for-profit and non-profit organizations, suggesting its potential to save the healthcare system $1.5 billion a year in turnover costs.
A new study by the University of Manchester has developed a way to measure the impact of urban traffic on city temperatures, revealing that everyday vehicle use can raise temperatures in cities. The researchers found that traffic heat increases simulated air temperatures by around 0.16°C during summer and 0.35°C in winter.
The American Association for the Advancement of Science (AAAS) and DataSeer are collaborating on a six-month pilot to automate MDAR checklists for manuscripts submitted to Science using AI technology. The partnership aims to improve research quality, reproducibility, and editorial efficiency by reducing manual effort.
Researchers found that maternal anxiety about radiation exposure during the Fukushima nuclear accident was linked to increased rates of preterm births, lower birth weights, and severe birth outcomes. Socioeconomic factors, such as education level and income, played a role in mitigating these effects.
Researchers from Chiba University found that antibody therapeutics with stronger Fcγ receptor binding are more likely to be recognized as foreign and associated with higher anaphylaxis risk. High affinities for Fcγ receptors critical determinants of anaphylaxis, study suggests.
A randomized trial found that duloxetine does not prevent painful neuropathy caused by oxaliplatin-based chemotherapy in patients with stage II or III colorectal cancer. The study suggests that duloxetine should only be used for managing existing neuropathy, not prevention.
A new study by the University at Buffalo reveals that unequal access to recycling facilities plays a key role in shaping plastic waste management practices in the US. Wealthier and more college-educated communities are more likely to have convenient access to large-scale industrial recycling facilities, making recycling easier and more...
Researchers have developed a new single-cell technology called CIPHER-seq that captures the timing of cytokine activity with greater accuracy. This allows for a clearer view of immune cell behavior and strengthens the foundation for understanding cancer, inflammation, and treatment resistance.
A large study led by Cedars-Sinai Health Sciences University found that long-term use of antidepressants and some antidiarrheal medications may be associated with a higher risk of death. The study analyzed nearly two decades of electronic health records from over 650,000 US adults with IBS.
A new open-access framework, Rapid Evaluation Framework (REF), allows researchers to compare model outputs with real-world observations, providing immediate insight into model performance. The REF accelerates climate model evaluation, making it possible for policymakers and communities to respond quickly to future climate change.
Researchers studied 10 couples, finding that the risk of gluten transfer through an open-mouth kiss is low and can be reduced to safe levels by waiting or drinking water after consuming gluten. This study aims to alleviate anxiety and social avoidance among those with celiac disease.
A recent study published in Journal of the American Geriatrics Society found that individuals with higher optimism have a lower risk of developing dementia. After analyzing data from the Health and Retirement Study, researchers discovered a 15% lower risk associated with a one-standard-deviation increase in optimism.
Research in New Phytologist reveals that plants can obtain essential nutrients like phosphorus and iron from atmospheric dust settling on their leaves. In a Mediterranean field study, dust application increased plant macronutrient and micronutrient concentrations through mildly acidic leaves.
Public long-term care insurance in China's pilot program cuts catastrophic health spending by up to 52%, shifting care away from costly medical interventions. This model offers a powerful alternative for value-based end-of-life care.
A study of 52 female nurses found a two-fold increase in salivary cortisol levels at midnight for those working double shifts compared to single shift workers. This suggests that extended shift schedules are associated with alterations in the circadian pattern of cortisol, reflecting increased physiological strain.
The new pattern-based technology offers two key advantages: simplified setup eliminates infrared illumination and enables universal deployment across multiple contexts. This system enables real-time detection of subtle eye movements in clinical applications, including neurological conditions such as Parkinson's and Alzheimer's diseases.
A recent study by the University of Eastern Finland found that young translocal forest owners in Finland often compromise on their values due to financial incentives and limited information on alternative methods. Sentimental value was identified as a key factor, with forests holding emotional significance for many owners.
Researchers found that changes in animal development due to climate shock persist even after three generations, leading to increased stress and adaptation. The study suggests that climate change can accelerate evolution by affecting gene expression and development time.
Researchers at KRICT developed a facile and scalable route for high-performance Ag2Se thermoelectrics, achieving a thermoelectric figure of merit (zT) of 0.927 at 120°C. The optimized material exhibited more than twofold improvements in compressive strength and Young’s modulus, enabling robust mechanical performance.
The UCI-OC Poll reveals nearly two-thirds of Orange County residents view Trump negatively, while Newsom fares only marginally better. A surge in independent support suggests a broader mood of pessimism and uncertainty, with voters hesitant to settle on their choices.
The 48th AChemS Annual Meeting will present cutting-edge research on chemosensory perception, including its implications for human health, behavior, and quality of life. The conference highlights new findings on the role of smell in eating behavior, disease diagnosis, and obesity treatments.
Research conducted by San Diego Zoo Wildlife Alliance and Save the Elephants found that elephants' gut microbiomes shifted significantly when sharing habitat with livestock. Microbes commonly found in livestock became more abundant, while beneficial microbes decreased.
Researchers developed a method to estimate vascular age from consumer wearables' PPG signals, predicting accurate results with a mean error of six to seven years. The technique uses a deep learning model and may lead to earlier detection of cardiovascular risk and more effective preventive care.
Australian nursing education is falling short in preparing graduates for disability care, with nearly 18% of Australians experiencing disability. Researchers recommend mandatory disability education accreditation standards and specialist pathways to address this gap.
A team of scientists has developed a new neural network called the mixture probability sampling network (MPSN) to create ultra-precision structural colors. The MPSN achieves high accuracy and diversity in solution output, overcoming limitations of existing methods.
Scientists in Japan developed a high-resolution X-ray telescope using precision mirror-making technology, capable of distinguishing objects 3.5 mm wide from 1 km away. The telescope was tested on the ground using a unique evaluation system before launch on the FOXSI sounding rocket mission.
A research team identified distinct subregions within the default mode network (DMN) that act as senders and receivers of information, enabling flexible shifts between perception and memory-driven thought. The study reveals that the DMN is not functionally uniform but composed of subregions with distinct connectivity biases.
A new study offers a powerful approach to personalized bladder cancer care using a non-invasive urine test. The test can detect minimal residual disease while accounting for mutations present in normal urothelium, allowing clinicians to distinguish between patients who benefit from additional therapy and those who don't.
The UNU Hub will foster interdisciplinary collaboration, innovation, and policy engagement to address AI's ethical challenges. It aims to establish trusted frameworks ensuring AI serves as a force for equity, sustainability, and human well-being, aligned with UN Sustainable Development Goals.
A new eight-week self-reflection program helps trainees deepen their understanding of cognitive behavioral therapy (CBT) and develop reflective skills. The study found that the program improved satisfaction, self-awareness, and reflective practice among participants, suggesting its potential to support CBT education.
The UNU Hub for AI-Finance at East China Normal University's Shanghai AI-Finance School aims to leverage AI to boost sustainable economic development and financial inclusion. The Hub will prioritize innovation-driven research, global talent training, and international policy advocacy to address the Global South's financial challenges.
A 300-million-year-old fossil previously thought to be the world's oldest octopus has been revealed to be a nautiloid relative, with modern synchrotron imaging techniques uncovering tiny teeth that prove its true nature. The discovery pushes back the known history of octopuses by around 150 million years.