A recent study found that common flea and tick control medications used in dogs and cats can contaminate ecosystems with toxic chemicals. Isoxazoline antiparasitic drugs, used globally since 2013, may harm dung-feeding insects, including flies and butterflies, which are crucial for nutrient cycling and soil health.
A team of researchers has identified the HIF1 protein as a central molecular driver of tendon diseases such as Achilles tendonitis and jumper's knee. Elevated levels of this protein lead to pathogenic remodelling of tendons, making them more brittle and impairing their mechanical function.
A large-scale study of nearly 147,000 women found that early or premature menopause is not associated with an increased risk of type 2 diabetes. Despite increased fat and insulin resistance during menopause, the study found no independent relationship between age or type of menopause and the onset of diabetes.
Researchers develop a novel approach to precisely encapsulate individual probiotics into microgels, enhancing survival and targeted delivery in the gastrointestinal system. The study demonstrates improved therapeutic efficacy in treating IBD using this technology.
A team of geoscientists has identified a massive underground reservoir of freshwater beneath the Great Salt Lake, extending thousands of feet below the playa. The aquifer is believed to contain water dating back to the Ice Age, which could provide a new source for restoring lakebed crusts and reducing dust storms.
Researchers used CRISPR/Cas9 to create rice mutants with increased oleic acid content and decreased linoleic acid levels. The study demonstrates a novel strategy for designing functional rice cultivars with improved nutritional value and stable agronomic traits.
The SUSA project is driving digital transformation in European healthcare education by delivering 20 bachelor's and 26 master's programs with advanced digital health competencies. This pan-European effort aims to graduate 6558 students and upskill 660 professionals, fostering interoperability and attracting top talent.
New research suggests Virtual Reality (VR) may support personal self-disclosure by offering anonymity through avatars and calming virtual environments. Nature-based VR settings proved particularly comfortable and suitable for therapeutic conversation.
A new study uses large language models and network analysis to quantify investor emotions' fragility. High emotional vulnerability is linked to unstable stock prices and lower returns.
Researchers at Kumamoto University have successfully grown a bulk inorganic crystal from water that emits circularly polarized light. This breakthrough material has the potential to revolutionize security printing, advanced displays, and photonic technologies with simple inorganic chemistry.
Researchers developed Zr-IR825 nanoparticles by combining IR825 with biocompatible metal zirconium, improving water solubility and stability. The material exhibited outstanding photothermal conversion capabilities under near-infrared light, effectively killing tumor cells while showing low toxicity to normal cells.
Researchers developed PDJA, a novel AI-based attack framework that amplifies vulnerability and bypasses defenses in multi-agent reinforcement learning systems. The approach improves attack effectiveness and cross-layer vulnerability exploitation, opening new opportunities for evaluating the robustness of AI-driven autonomous systems.
A study by Iowa State University researchers found that anthropomorphizing language, such as using mental verbs like 'think' or 'know', is less common in news writing than expected. When used, these words often describe what AI requires to function, rather than attributing human-like qualities to the system. The research team identifie...
A new method uses tiny crystals of zircon to study the past evolution of Australian landscapes, offering insights into how the environment responds to geological processes and climate change. The approach provides valuable information on the storage and reworking of sediments near the surface over millions of years.
Researchers at Nagoya University found that about half of wood mice take time to examine nuts before selecting, potentially increasing their exposure to predators. Despite this risk, the extra time investment pays off as picky eaters are more likely to select undamaged chestnuts.
The guide, based on scientific documents, provides accessible language for parents and coaches to recognize concussions in young athletes. Early recognition and removal from sport are correlated with quicker returns to competition, emphasizing the importance of 'recognize and remove'.
A recent Buck Institute study revealed that spaceflight accelerates aging due to changes in immune cell composition and epigenetic markers. However, researchers also found evidence of intrinsic rejuvenation factors that can counteract these age-accelerating stressors.
A machine learning model has identified the most important drivers of cancer survival in nearly all countries, highlighting factors such as national wealth, access to radiotherapy and universal health coverage. The model provides data-driven roadmaps for policymakers to prioritize resources and close survival gaps.
The study found that medical tourism postoperative complications may cost the NHS up to £20,000 per patient. The analysis of existing data revealed that patients who underwent surgery abroad were more likely to experience moderate to severe complications, with treatment costs ranging from £1058 to £19,549.
Moderate-intensity physical activity for an extra five minutes a day can reduce all deaths by 10% in most adults, while reducing sedentary time by 30 minutes per day can lead to a 7% reduction in deaths.
A new study published in BMC Medicine found that higher maternal blood pressure increases the risk of preterm delivery, smaller babies, and gestational diabetes. The research used Mendelian randomization to assess the link between maternal blood pressure and 24 adverse pregnancy outcomes, revealing clear causal effects.
A new study reveals that young people are at risk of engaging in serious online offenses through gradual progression from low-risk behaviors like digital piracy. Researchers found that nearly half reported engaging in illegal online behavior early on, with many describing a pattern of repeat offending.
Smartphone apps based on psychological theories are 3 times more effective than minimal support in helping people quit smoking long-term. The apps improve sustained abstinence rates when combined with traditional interventions or pharmacotherapy.
The prevalence of overweight and obesity in Africa has surged, with a significant increase in obesity over the past two decades. Women are nearly five times more likely to be obese than men, while those with tertiary-level education are three times more likely. The study's findings highlight the need for targeted public health interven...
A new study from the University of Hawaii at Mānoa challenges a 50-year-old narrative about Native Hawaiian birds, finding no evidence they were hunted to extinction. Instead, the authors suggest climate change, invasive species, and land-use changes led to the disappearances.
Combining enzymes with biochar breaks down pollutants into less harmful compounds, improving efficiency and durability. Biochar-immobilized enzymes have demonstrated impressive results in water treatment and soil remediation.
A phase 1/2 trial investigating autologous T cell therapy targeting multiple tumor antigens showed promising results in patients with advanced and surgically resectable disease. Patients responded well to the therapy, with high disease control rates and low adverse side effects.
Researchers found that biochar can soften the impacts of swings between wet and dry conditions on soil organic carbon breakdown. The study showed that stronger moisture variability speeds up decomposition and boosts microbial activity, but biochar addition helped stabilize the soil system under variable moisture conditions.
Researchers analyzed faecal samples from 82 captive and 16 wild marsupials, revealing new microbial species and antimicrobial resistance. The study found that host family, location, and diet contributed to variance between different microbiomes.
Engineered biochar shows promise in boosting crop yields, suppressing soil-borne diseases, and remediating contaminated land. Purpose-specific design is essential for optimal performance.
A study found that a small, implanted vagus nerve stimulation device produced substantial and sustained improvements in depressive symptoms, quality of life, and daily function in patients with treatment-resistant depression. The device showed lasting benefits even after two years, with nearly one-third of participants who didn't respo...
Researchers developed a tool to predict when deadly salmonella outbreaks are likely to happen in wild songbird populations, allowing people to protect their feathered friends. The system is based on climate patterns, tree cone production, and avian migrations.
A new study from the University of Notre Dame found that satellite-derived forest maps often disagree, creating uncertainty for conservation, climate, and development policies. The discrepancies can be as high as a factor of 10, affecting millions of hectares and human lives.
A study funded by the National Cancer Institute aims to test a low-cost intervention using future-focused thoughts to help people quit smoking. The project will examine the effectiveness of episodic future thinking in reducing impulsivity and promoting healthier choices.
Dr. Timothy Riddell has been appointed as the new executive vice president and chief operating officer of Ochsner Health, with a focus on guiding the system's long-term goals for sustainability and success. He brings 28 years of experience within the Ochsner group practice to his new role.
The journal is seeking early-career scientists to serve on its editorial team, providing hands-on experience and mentorship. Selected members will play an active role in shaping the journal's scientific vision and community engagement.
Dr. Kelley's discovery of the Lost City Hydrothermal Field revolutionized scientific understanding of fluid–rock interactions and chemosynthetic ecosystems. Her work has also transformed ocean observation through the NSF's Ocean Observatories Initiative Regional Cabled Array.
Researchers discovered chemosynthetic microbial communities formed wrinkle structures in ancient turbidites, which should not have existed in the deep-water setting. The team analyzed geologic evidence and determined that the sediment layers were indeed turbidites with biotic textures.
Pennington Biomedical researchers investigated competing body weight regulation models, analyzing the interaction of energy intake and expenditure. The study highlights the need to test state-of-the-art technology and could help explain why losing weight is challenging for some individuals.
Zhongping Lee received the 2026 Nils Gunnar Jerlov Medal for his transformative contributions to understanding light interaction with the ocean. His work reshaped ocean color science, enabling robust global observations of ocean transparency and productivity from satellites.
Researchers developed ZENN, an AI framework that recognizes and adapts to hidden differences in data quality. By using thermodynamic principles, the model distinguishes meaningful signals from uncertainty and noise.
Marine darkwaves are short-term episodes of underwater darkness that can severely impact kelp forests, seagrass beds, and other light-dependent marine life. The researchers developed a framework to compare these events across the globe, finding between 25-80 marine darkwaves along the East Cape since 2002.
The American Physical Society's Global Physics Summit will convene over 14,000 physicists worldwide for groundbreaking research presentations. The event will feature both in-person and online experiences, including scientific sessions, exhibits, and networking events.
Large language models (LLMs) provide treatment recommendations for early-stage hepatocellular carcinoma (HCC) that align with clinical guidelines. However, their performance is limited in late-stage disease, where they prioritize tumor factors over liver function. LLMs should be used as a supplement to clinical expertise.
The American College of Chest Physicians released a new clinical guideline on biologic management in severe asthma. The guideline provides evidence-based recommendations for selecting biologics for different patient populations, considering factors such as baseline oral corticosteroid use and comorbid conditions.
Researchers found that targeting lipid metabolism in tumors can lead to ferroptosis, a type of cell death dependent on fat molecules. This could pave the way for new cancer treatments that target specific mechanisms responsible for lipid processing by tumors.
Researchers found two genes, mask and clu, that regulate dopamine levels in the brain and influence behavior. Silencing these genes changed sleep patterns and response to caffeine in fruit flies, providing insights into potential treatments for neurological disorders.
In a new study, terrestrial bacteria-infecting viruses were able to infect their E. coli hosts in near-weightless conditions aboard the ISS, but with distinct mutations. The dynamics of virus-bacteria interactions differed from those observed on Earth, highlighting potential insights into microbial adaptation and human health.
A deep learning model trained on stage II colorectal cancer whole slide images accurately identified features linked to recurrence risk. The study found the model surpassed clinical prognostic parameters in predicting patient outcomes.
A Phase I study led by Timothy Yap demonstrates the potential of linavonkibart to target and prevent activation of transforming growth factor-beta 1 (TGFβ1), overcoming treatment resistance in multiple cancers. The trial showed manageable safety profiles and objective responses in heavily pre-treated patients, suggesting a promising ne...
A recent SFU study analyzed 3,200 Strava posts from Metro Vancouver runners between 2010 and 2021 to understand what makes running enjoyable. The research identified six key factors shaping runner experiences: psychological aspects, social connections, weather, surroundings, physical sensations, and path conditions.
Researchers analyzed the genome of over 100 koalas and found that two retroviruses are causing cancer deaths. They also discovered that some Koala Retrovirus (KoRV) integrations may be beneficial to koala health, increasing longevity or reproductive output.
Key imidazolyl groups induce phenylalanine flipping, significantly enhancing the cellular potency of BRD9 inhibitors for treating acute myeloid leukemia (AML). The compounds demonstrated potent binding affinity and anti-tumor efficacy in the MV4-11 xenograft mouse model.
Researchers develop a new fabrication approach to produce multi-element optical components for super-resolution imaging, enabling customized imaging systems. The technique uses consumer-grade 3D printers and low-cost materials, producing high-performance lenses at a cost of less than $1 each.
Research reveals molecular interaction between environmental and genetic risk factors triggers MS. EBV and gene variants HLA-DR15 haplotype play key roles in disease onset.
A new consensus statement provides evidence-based guidance for screening, diagnosis, treatment, and return-to-play protocols for female athletes. The updated report includes a first-of-its-kind adolescent model of the Female Athlete Triad, addressing energy deficiency in growing adolescents.
A multidisciplinary team of world-leading experts is developing an off-the-shelf engineered product that could address liver failure in millions of patients. The ImPLANT project aims to create synthetic biology-based gene circuits in human induced pluripotent stem cells to drive cell differentiation into all required liver cell types.
Women with a genetic predisposition to higher body mass index are at increased risk of all-cause mortality after breast cancer diagnosis. Targeted lifestyle recommendations can mitigate this risk.
A new hybrid wireless access network called PHWAN has been proposed to improve the performance of smart factories. The framework combines different wireless systems, including 5G, Wi-Fi, and low-power industrial networks, to adapt dynamically to the needs of different machines.
Research reveals that fat located near the colon contains an unusually high number of inflammatory fat cells and immune cells, suggesting a unique function in communicating with the immune system in the gut region. This tissue may be an adaptation to the gut microbiome and could contribute to amplifying or sustaining inflammation.