Nature Chemical Biology
Experimental study
Human tissue samples
Accelerated RNA detection using tandem CRISPR nucleases
5-Aug-2021
Using two CRISPR enzymes, a COVID diagnostic in only 20 minutes
The reactions involved in the FIND-IT assay to detect infection with the SARS-CoV-2 virus. When the Cas13 enzyme (bottom left) binds to its target RNA, it snips a molecule (orange and light blue ribbon) to release an activator (orange) that supercharges the Csm6 nuclease (right) to cleave and release fluorescent molecules that light up (green) and signal the presence of viral RNA. Credit: Artwork courtesy of Margaret L. Liu, University of Chicago Pritzker School of Medicine
Additional Media
The reactions involved in the FIND-IT assay to detect infection with the SARS-CoV-2 virus. When the Cas13 enzyme (left) binds to its target RNA, it snips a molecule (orange and grey) to release an activator (orange) that supercharges the Csm6 nuclease (bottom center) to cleave and release fluorescent markers that light up (green) and signal the presence of viral RNA. Credit: Artwork courtesy of Margaret L. Liu, University of Chicago Pritzker School of Medicine
Article Information
Journal
Nature Chemical Biology
Method of Research
Experimental study
Subject of Research
Human tissue samples
Article Publication Date
2021-08-05
Article Title
Accelerated RNA detection using tandem CRISPR nucleases
Contact Information
How to Cite This Article
APA:
University of California - Berkeley. (2021, August 5). Using two CRISPR enzymes, a COVID diagnostic in only 20 minutes. Brightsurf News. https://www.brightsurf.com/news/1GRRX458/using-two-crispr-enzymes-a-covid-diagnostic-in-only-20-minutes.html
MLA:
"Using two CRISPR enzymes, a COVID diagnostic in only 20 minutes." Brightsurf News, Aug. 5 2021, https://www.brightsurf.com/news/1GRRX458/using-two-crispr-enzymes-a-covid-diagnostic-in-only-20-minutes.html.