Articles tagged with Medical Tests
The NHS Clinical Entrepreneur Programme has supported the creation of 691 businesses, generating 5,184 jobs and raising over £1.27 billion in investment. The programme continues to play a critical role in retaining talent within the NHS by enabling clinicians to develop their ventures alongside their clinical careers.
Researchers at Texas A&M University develop a laser technique called TRIP to directly measure quantum forces shaping proteins, enabling accurate prediction of how pharmaceutical drugs interact with them. This breakthrough could lead to the design of medicines tailored to specific diseases, revolutionizing precision medicine.
The study's findings suggest that adults can reduce their likelihood of severe COVID-19-associated outcomes by obtaining a 2025-2026 COVID-19 vaccination. Receipt of the vaccine was associated with additional protection against medically attended COVID-19, including emergency department/urgent care encounters and hospitalizations.
A new blood test, Stockholm3, detected significantly more aggressive prostate cancers than the PSA test without increasing unnecessary follow-ups. The study shows that Stockholm3 identifies 90% of aggressive cancer cases, compared to 74% for PSA.
A cross-sectional study found that colorectal cancer screening participation increased after an organized population screening program, but socioeconomic disparities remained. Younger age groups, single households, and lower-income individuals still lag behind in screening uptake.
Researchers developed a simple blood-based assessment to evaluate high-density lipoprotein's (HDL) cholesterol removal capacity from blood vessel walls. The study linked low HDL function to high-risk coronary plaques, supporting the use of this method for predicting cardiovascular risk.
A recent study found that melanoma disproportionately affects Florida's senior population, with older men experiencing twice as many skin cancer-related deaths as women. The study highlights gaps in prevention and early detection, particularly among men and non-Hispanic populations.
Researchers used an open-source AI model called Mirai to quickly identify high-risk patients and expedite their diagnostic process. This led to a significant reduction in wait times, with some women receiving biopsy results within days of having their mammograms done.
The study found that population-based pathogenic variant testing reveals different subsets of high-risk women than clinical risk factors and polygenic risk scores. This highlights the importance of incorporating PV testing into risk-based screening for breast cancer.
A new laser-based process is set to revolutionize photonics manufacturing by removing manual calibration, which accounts for over half of production costs. The technology promises faster, cheaper, and precise manufacturing at sub-micron tolerances.
A population-based screening trial evaluating a cell-free DNA multicancer early detection test found modest increases in diagnostic delay rates for head and neck, lung, and upper gastrointestinal cancers. These findings suggest that future trials may need to consider system-level spillover effects on healthcare resources.
The American Cancer Society has endorsed two new types of stool tests and recommends limiting the use of blood tests for colorectal cancer screening. The guidelines aim to encourage people to get screened while improving detection rates.
A new blood test, called VeloCD, can predict how a patient's illness will progress and how well they will respond to treatment. The test analyzes key markers in the blood that reveal gene expression patterns, allowing for accurate predictions of future clinical states.
Researchers at the University of Texas MD Anderson Cancer Center have identified specific blood-based genomic biomarkers that distinguish inflammatory breast cancer from other subtypes. The study used an improved method of RNA sequencing, called TGIRT sequencing, which allowed for a more comprehensive overview of all RNA types and amou...
Elective MRI screenings may lead to false positives, unnecessary surgery, and emotional harm. Experts argue that detecting certain cancers early is not always beneficial, and the scans can exacerbate anxiety rather than improve quality of life.
Researchers found that accelerated biological aging of a type of white blood cell called monocytes is linked to cognitive and mood-related symptoms of depression. This discovery could lead to earlier diagnosis and personalized treatment for depression, particularly in high-risk populations such as women with HIV.
A new portable device can deliver accurate test results for tuberculosis (TB) in less than half an hour, matching lab accuracy. The MiniDock MTB uses similar technology to COVID-19 tests and detects DNA of mycobacterium tuberculosis, enabling rapid diagnosis and treatment
Researchers developed an AI tool that analyzes routine electronic health records to predict ADHD risk in children years before a typical diagnosis. The model accurately identified risk in children age 5 and older, with consistent performance across patient characteristics.
A new analysis found that prescriptions for curable hepatitis C drugs have declined sharply in recent years, leaving millions without treatment. The researchers urge swift actions to deliver the drugs to those who need them, including increased screening and system-level changes.
A recent study identified distinct microbial signatures in the oral cavity and gut that serve as robust biomarkers for early gastric cancer detection. These microbial markers can be detected in saliva or stool samples using machine learning models, achieving an AUROC of 0.87 for saliva-based detection.
Researchers created a new polymer electrode that conforms to the skin, is comfortable, and can pick up ECG signals without gel or adhesives. The technology performed comparably to existing sensors in proof-of-concept testing, showcasing its potential for practical and cost-effective health monitoring applications.
A community-based point-of-care HCV RNA testing program was feasible and led to a high percentage of same-day treatment for American Indian and Alaska Native participants. The study supports expanding point-of-care HCV RNA testing and integrated treatment to advance HCV elimination.
A new analysis from UC San Francisco argues that diagnostics are being overlooked, slowing progress against major diseases despite advances in targeted therapies. The study suggests that nearly half of the world's population lacks adequate access to diagnostics due to inadequate investment and insurance reimbursement.
A national survey found significant disparities in IBS diagnosis across sex and racial groups in the US. Men and Black patients are less likely to receive a formal diagnosis compared to women and white patients, despite similar reported healthcare-seeking behavior and symptom severity.
A randomized trial found that duloxetine does not prevent painful neuropathy caused by oxaliplatin-based chemotherapy in patients with stage II or III colorectal cancer. The study suggests that duloxetine should only be used for managing existing neuropathy, not prevention.
Advanced or metastatic cancers often go without tumor genomic testing, with those from low-income backgrounds facing longer wait times. JAMA Network Open highlights the need for targeted healthcare policies to bridge these gaps.
The Alliance for Clinical Trials in Oncology is enrolling adolescent and young adult cancer patients in various trials, including genetic services and treatment studies. These trials aim to address longstanding gaps in care and improve outcomes for AYAs with cancer.
Researchers at Charité develop test to determine circadian rhythm using hair roots, revealing genetic and lifestyle factors influencing internal clock. The new method shows promise for tailoring therapies to individual rhythms, potentially improving treatment outcomes.
Researchers discovered subtle changes in the blood can reveal early signs of cognitive decline caused by chemicals produced by gut bacteria. A blood test may one day transform how we detect dementia, potentially identifying people at risk years before symptoms appear.
Researchers developed a physics-based model for competitive lateral flow assay (LFA) test strips, improving commercial fentanyl test strips' sensitivity. The new method enables actionable guidance for sensitivity optimization across various LFAs.
Researchers are developing a comprehensive diagnostic toolkit to detect lymphatic disorders earlier and as part of routine physical exams. The team, led by Dr. Zhenpeng Qin, is working on identifying biomarkers for lymphatic diseases through blood samples.
A study found that inflammation markers may signal depression in women with type 2 diabetes, but vary based on depression symptoms and measures. The research suggests a path toward precision mental health by identifying specific inflammatory biomarkers linked to different dimensions of mental health.
A cohort study found that smokers with negative baseline low-dose computed tomography findings had a significantly increased long-term lung cancer risk, becoming apparent only after two years of screening. This suggests supporting extended initial screening intervals and personalized long-term monitoring based on smoking history.
Professional dancers experience high levels of physical strain and ergonomic stress, with 25% developing osteoarthritis by their late twenties. The study suggests optimizing training sessions, flooring, and organizational changes to reduce injury risk and wear-related conditions.
A decrease in colorectal cancer incidence was observed among individuals with negative screening colonoscopy results, particularly men, suggesting risk-based follow-up strategies. Nonadherence to scheduled colonoscopies increased the risk of CRC, highlighting the need for targeted interventions to improve early detection.
Researchers developed a computational tool that infers telomere length from structural changes in cells and tissues captured in medical biopsies. The TLPath model accurately predicts telomere length, providing new opportunities for studying human aging.
Researchers found that treating severe fetal megacystis with a vesicoamniotic shunt in the first trimester can improve survival rates and kidney function. In the study, 75% of children were born alive and 68% survived their first year of life, with most showing normal or only slightly impaired kidney function.
A new imaging test, PSMA PET/CT scan, has been shown to safely reduce the number of biopsies needed for suspected prostate cancer, with no harm to patients. The PRIMARY2 trial found that the scan could identify low-risk patients who did not need a biopsy, while targeting suspicious areas for those who did.
Emerging research across conceptual frameworks, biomarker science, digital phenotyping, and artificial intelligence synthesizes a translational pathway toward a more biologically grounded and clinically useful approach to psychiatric diagnosis. The current system falls short due to standardized clinical language and lack of biological ...
The Alliance for Clinical Trials in Oncology is spotlighting new trials for colorectal cancer in March, focusing on early detection methods and treatments for treatment delays and loss of appetite. The trials aim to improve patient outcomes, with several enrolling patients with newly diagnosed colon or rectal cancer.
Cancer cell-derived small extracellular vesicles can be excreted into urine, according to researchers who tracked their journey in mouse models. The study reveals that glomerular cells actively transport sEVs across the filtration barrier, supporting their use in emerging urine-based cancer diagnostics.
Researchers studied Norwegians with reported chronic health problems linked to tick bites, finding no objective evidence of persistent infections. The study suggests that physical activity and labour force participation may be more related to symptoms than tick exposure.
A new study suggests that AI can help doctors detect serious heart valve disease years earlier, potentially saving thousands of lives. The AI algorithm correctly identified 98% of patients with severe aortic stenosis and 94% of those with severe mitral regurgitation.
A new imaging technique using ultrasound-guided diffuse optical tomography can reduce unnecessary benign breast biopsies by nearly 25%, according to a recent study. The technology uses near-infrared light to create 3D pictures of tissues, revealing functional differences between normal and cancerous tissue.
The use of next-generation sequencing in newborn screening can detect a wide range of genetic disorders, some of which are not currently testable through traditional means. This approach enables earlier disease detection and long-term health planning.
A new diagnostic platform enables rapid and accurate detection of drug-resistant C. auris pathogens using CRISPR technology, allowing for more effective treatment and prevention of hospital outbreaks. The dSHERLOCK test can detect the presence of mutations causing antimicrobial resistance in just 40 minutes.
A new rapid test for hepatitis C could identify more patients who can be cured if insurers increase reimbursement to cover the test's high cost. The test's point-of-care feature makes it ideal for early screening and treatment in clinics and emergency rooms.
A national longitudinal cohort study found consistently worse mental health outcomes among middle-aged and older adults at high risk of obstructive sleep apnea. Integrated screening and intervention strategies are needed to address this association.
Researchers found large language models susceptible to malicious input manipulation, leading to potentially hazardous health recommendations. The study highlights the need for robustness testing and regulatory oversight before clinical deployment of these AI tools.
Researchers describe first reported mpox transmission of clade Ib in a healthcare setting outside Africa, with Ireland's nosocomial outbreak linked to local cases. In the Democratic Republic of Congo, community transmission shifted from sexual to non-sexual routes, driven by factors like overcrowding and child malnutrition.
A new diagnostic method using AI and genetic information can accurately identify pneumonia in critically ill patients, distinguishing between infectious and non-infectious causes. The model has been shown to reduce inappropriate antibiotic use by over 80% and could lead to faster diagnosis and improved patient outcomes.
Researchers developed a new diagnostic chip that can detect tumor cells in blood, allowing for real-time monitoring of brain cancer treatment effectiveness. The GlioExoChip uses extracellular vesicles to assess treatment response, providing a quick and minimally invasive way to inform doctors about chemotherapy efficacy.
A novel diagnostic approach enables rapid detection of both antibiotic resistance and high virulence in Klebsiella pneumoniae, a microorganism driving the global antibiotic resistance crisis. This breakthrough could support timely, targeted therapy and strengthen infection-control strategies in healthcare settings.
A secondary analysis of the WISDOM trial found a substantial number of women with clinically actionable genetic variants, many not qualifying for current guidelines. This study supports broader access to genetic testing for personalized breast cancer risk assessment.
Scientists at Northwestern University have developed the fastest test yet for diagnosing hepatitis C virus, delivering results in just 15 minutes – up to 75% faster than current rapid tests. The highly accurate diagnostic could revolutionize HCV care by improving diagnosis and accelerating treatment uptake.
Researchers developed a novel magnetic biosensing technique using polydopamine-coated magnetoliposomes to monitor lectin-glycan binding. The technique provides insight into the dynamics of sugar-protein interactions and holds promise for medical diagnostics, glycoscience research, and drug discovery.
The UCF Health Mobile Health Clinic provides free high-quality healthcare services to underserved communities, serving as a real-world classroom for medical and nursing students. The clinic aims to reduce preventable conditions and improve long-term health through comprehensive screenings, chronic disease monitoring, and education.
A new study suggests that sweat can reveal information about a person's health, including hormone levels, medication doses, and early detection of diseases like diabetes and cancer. Wearable sensors using artificial intelligence can detect specific metabolites in sweat, providing personalized health insights.