About The Study: In this study, receipt of 2025-2026 COVID-19 vaccination was associated with additional protection beyond existing immunity in adults against medically attended COVID-19, including emergency department/urgent care encounters and hospitalizations, compared with no receipt of a 2025-2026 vaccine dose. These findings suggest that adults can reduce their likelihood of severe COVID-19–associated outcomes by obtaining a 2025-2026 COVID-19 vaccination.
Corresponding Author: To contact the corresponding author, Ruth Link-Gelles, PhD, MPH, email hzt7@cdc.gov .
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(doi:10.1001/jamanetworkopen.2026.25152)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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