Articles tagged with Covid 19 Vaccines
A new commentary calls for consistent evaluation of potential links between COVID-19, vaccination, and cancer, highlighting potential associations and biological mechanisms. The author argues that similar mechanisms reported in connection with COVID-19 vaccination warrant consideration and further study.
A study of 60,980 US adults with autoimmune rheumatic conditions found that those who received updated COVID-19 vaccines had a 69% lower adjusted odds of COVID-19-related hospitalization compared to those who received only the initial series vaccines or were unvaccinated. The completion of the initial series and booster vaccination als...
Researchers discovered a lower risk of subsequent type 1 diabetes development among individuals under 30 who had COVID-19, especially among unvaccinated individuals. The study found a 16% reduced risk across all variants combined and a 42% lower risk 31-180 days post-infection.
A 2-year multicenter cohort study found that most hospitalized survivors maintained or regained cognitive function after Omicron infection, while older and reinfected patients may face progressive decline. The study identified age, infection history, and disease severity as risk factors for progressive decline.
A team of researchers at North Carolina State University has created a novel approach to optimize vaccine distribution by combining machine learning with column generation. This method accelerates run-time for the optimization model by 79.1% while maintaining high-quality solutions.
Researchers have created a new approach to cancer vaccine design by leveraging pre-existing antiviral immune memories. PROTEXI, a dendritic cell vaccine platform, converts dormant antiviral memory into a catalyst for antitumor immunity, slowing tumor growth and improving survival in multiple preclinical models.
A survey of U.S. adults found that most are unaware of the CDC's vaccine recommendations during pregnancy, with uncertainty prevailing across four vaccines and the Covid-19 vaccine. Women aged 18-49 were significantly more informed about the recommended vaccines than other age groups.
Researchers found that mRNA-based COVID-19 vaccines effectively protected Schistosoma-infected mice against SARS-CoV-2, with strong spike-specific antibody responses and CD4 T-cell immunity. The findings suggest that chronic helminth infection does not necessarily compromise vaccine-induced protection.
A new study reveals that Republican lawmakers sponsored 86% of antivaccine bills introduced in state legislatures after the COVID-19 pandemic. Meanwhile, Democratic lawmakers supported provaccine bills, highlighting partisan polarization's impact on vaccine access and public health.
A global vaccine trial evaluated fractional doses of COVID-19 boosters, finding they produced strong immune responses comparable to full-dose boosters. This could lead to extended vaccine supplies, improved equity in vaccination programs and reduced costs, especially in low-income countries.
Researchers found that COVID-19 vaccine boosters provide protection against some future coronaviruses that risk spreading from animals to humans. The study also showed that the immune response 'locks in' after the first exposure to SARS-CoV-2, impeding the ability to respond to future variants.
A study found that administering COVID-19 and influenza vaccines on the same day is not associated with an increased risk of serious or clinically meaningful adverse events. The research, published in Annals of Internal Medicine, involved 2.5 million patients in the US Department of Veterans Affairs health care system and compared thos...
The study's findings suggest that adults can reduce their likelihood of severe COVID-19-associated outcomes by obtaining a 2025-2026 COVID-19 vaccination. Receipt of the vaccine was associated with additional protection against medically attended COVID-19, including emergency department/urgent care encounters and hospitalizations.
The study found that COVID-19 vaccination was associated with a reduced risk of COVID-19-associated major adverse cardiovascular event (MACE), particularly among older adults and those with comorbidities. The vaccine also showed a substantial protective effect against all-cause MACE, suggesting its benefits extend beyond detected SARS-...
The study found that 2024-2025 COVID-19 vaccination significantly reduced the likelihood of medically attended COVID-19-associated outcomes among immunocompetent and immunocompromised adults. This highlights the importance of adults receiving recommended COVID-19 vaccinations to prevent severe illness.
Vaccines administered in autumn and winter 2025 to 2026 showed substantial short-term effectiveness but low uptake. This results in approximately 55% effectiveness against symptomatic COVID-19 among older adults within 2 months of vaccination, missed opportunities for preventing symptomatic disease among unvaccinated vulnerable groups.
A new study identifies five core values shaping COVID-19 vaccination decisions among Black and Hispanic parents, including safety, knowledge, trust, humanity, and autonomy. Understanding these values can inform targeted public health campaigns to reduce racial disparities in childhood vaccination rates.
A new COVID-19 vaccine adjuvant has been developed that can extend vaccine protection for up to two years, reducing the need for repeated boosters. The adjuvant, known as mannadjuvant, was created from a fungal component and showed a more pronounced response against omicron viral components than the vaccine alone.
A recent cohort study found that COVID-19 vaccination is associated with a lower risk of SARS-CoV-2 transmission. The study suggests that vaccination may indirectly reduce overall exposure to the virus.
A study of over 400 pregnant women found that vivid mental images are directly linked to their opinion of vaccines and whether they get vaccinated. Positive mental images were associated with increased vaccination rates, while negative images predicted higher hesitancy towards certain vaccines.
A Canadian study found that seasonal COVID-19 vaccination significantly reduced the risk of illness in 2025/26, with vaccine protection extending beyond its target strain. The vaccine was particularly beneficial for people aged 65 or older, offering 53% effectiveness against severe COVID-19.
Paxlovid helps vaccinated adults recover faster from COVID-19, but does not reduce hospital admissions or deaths. The drug significantly reduces viral load and side effects, making it a valuable treatment option for higher-risk patients.
Among highly boosted patients with cancer, overall postacute sequelae risk was not elevated compared to noninfected patients; hospitalized COVID-19 patients remained at increased risk despite therapeutics. Vaccination and boosting remain important in mitigating long COVID among immunocompromised patients
Severe COVID-19 and influenza infections can prime the lungs for cancer development, according to new research. Vaccination, however, largely prevents these changes, suggesting a reduced risk of lung cancer.
A York University-led study used machine-learning models to analyze 64 immune biomarkers in people with and without HIV who received COVID-19 vaccines. The researchers found clear vaccine-initiated immune response biomarkers between the two groups, but also identified outliers that provide insights into the complex nature of the immune...
A study of over 50,000 pregnant women in Norway found low vaccination rates against COVID-19 and influenza, with only 29.9% and 12.1% vaccinated respectively. The study highlights the need for targeted strategies to improve vaccination uptake among expectant mothers.
A multinational study found that COVID-19 vaccination during pregnancy significantly reduces the risk of preeclampsia. The study suggests that maternal vaccination may influence pathways involved in preeclampsia development, potentially offering protection even in the absence of COVID-19 infection.
A new study of over 3 million adults found that booster vaccines reduced the risk of COVID-19-related hospitalization and death. The effectiveness was similar for Moderna and Pfizer-BioNTech booster vaccines, but protection declined over time.
A new commentary raises concerns about editorial bias in scientific publishing, particularly in relation to COVID-19 vaccine safety and efficacy. The authors highlight the rejection of a case report and literature review that raised potential links between mRNA vaccines and rare blood cancers.
A case report investigates a woman's development of acute lymphoblastic leukemia and lymphoblastic lymphoma after receiving her second dose of the Pfizer-BioNTech COVID-19 mRNA vaccine, highlighting potential genetic and molecular mechanisms involved in disease pathogenesis.
A survey by the Annenberg Public Policy Center found that a strong majority of Americans view the MMR vaccine as safe relative to other vaccines. However, the number of people holding this view is below the threshold required for community immunity, which is worrisome.
A study from Linköping University in Sweden found no association between COVID-19 vaccination and decreased childbirth rates. Researchers analyzed data on over 60,000 women and found no statistically significant difference between vaccinated and unvaccinated groups.
The study found that 2024-2025 COVID-19 vaccines offer protection against COVID-19 hospitalization and severe in-hospital outcomes. Monitoring vaccine effectiveness remains crucial to guide vaccine composition and recommendations.
A recent poll found that 42% of people over 50 haven't gotten either flu or COVID-19 vaccines in the past six months. The leading reason for not getting vaccinated was a lack of perceived need, despite clear evidence showing vaccination reduces the risk of serious illness and death in older adults.
A global review of COVID-19 vaccination and infection cases found associations between the two and certain types of cancer. The study analyzed 69 publications and identified potential biological mechanisms, including immune responses and inflammation.
The CDC recommends shared clinical decision-making for some childhood vaccinations, allowing parents to choose or skip certain vaccines. However, a survey found that many Americans are unclear about what this means and who can be included as health care providers in the discussion.
A new survey by the Annenberg Public Policy Center finds a small but significant drop in the proportion of the public that would recommend getting the MMR vaccine, citing concerns over its safety and effectiveness. The survey also shows declines in perceived safety and effectiveness for other vaccines, such as seasonal flu and Covid-19.
A new study reveals that COVID-19 vaccination influences long-term immunity, with those vaccinated first showing stronger antibody responses to Omicron variants. The study found higher levels of IgG and IgA antibodies in vaccinated individuals, but a stronger T-cell response in those infected first.
A UBC-led study found that COVID-19 vaccination significantly reduces hospitalization, intensive care admission, and preterm birth risks for pregnant women. Vaccination is associated with lower risks even as the virus evolved from Delta to Omicron variants.
A new white paper by biostatistician Professor Jeffrey S. Morris analyzes the multicomponent US vaccine safety monitoring system, including VAERS and other components. The study suggests improvements to enhance the system's effectiveness and sustain a robust safety monitoring infrastructure.
Research published in Contemporary Economic Policy reveals that US cities' indoor vaccine mandates did not significantly increase vaccination rates or reduce COVID-19-related outcomes. The findings challenge assumptions about the effectiveness of local public health interventions.
Researchers discovered a 'sticky' molecule, P-selectin, that can cause blood clots and organ failure during COVID-19. A new mRNA therapy that drives P-selectin expression provides broad protection against coronavirus infection.
A new study found that COVID-19 vaccination is associated with a significant reduction in infections and allergic complications among children with atopic dermatitis. The researchers analyzed data from over 5,700 vaccinated and unvaccinated pediatric patients and found lower rates of multiple infections and allergic conditions.
Researchers found RSV to be of comparable severity to influenza and COVID-19, with higher death rates and intensive care admissions. Long-term cardiovascular and neurological complications were also observed up to 300 days post-hospitalisation.
A new study analyzing linked electronic health records found that COVID-19 infections led to a higher and longer-lasting risk of rare heart complications, including myocarditis and thrombocytopenia, compared to vaccination. The research team estimated an additional 2.24 cases of myocarditis per 100,000 children after COVID-19 infection.
The 2024-2025 COVID-19 vaccines demonstrated effective protection against severe disease and similar effectiveness against different subvariants. However, their effectiveness declined over time.
Patients with advanced lung and skin cancer who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy drugs lived significantly longer. The vaccine was associated with a near doubling of median survival, from 20.6 months to 37.3 months in lung cancer patients.
A recent study found that patients with advanced lung and skin cancer who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy drugs lived significantly longer than those who did not get the vaccine. The observation marks a significant step toward a long-awaited universal cancer vaccine to boost tumor-fighting eff...
A cohort study of mRNA COVID-19 vaccine exposure in the first trimester found no association with major congenital malformations. The study supports the safety of mRNA COVID-19 vaccines during early pregnancy.
A new pediatric study found that young people infected with COVID twice are twice as likely to develop long COVID, with increased risks for heart disease, damaged kidneys, cognitive issues, and more. The study analyzed data from over 407,000 patients across 40 pediatric hospitals.
A recent survey found that only 38% of US adults recommend taking a Covid-19 vaccine during pregnancy, while only 42% believe it is safe. Women aged 18-49 are even less likely to support vaccination, with 36% and 28% respectively, suggesting a decline in vaccination rates among childbearing women.
A Japanese study has identified four distinct patterns of immune response after COVID-19 vaccines, with a 'rapid-decliner' group experiencing faster decline in antibody levels. Monitoring changes in antibody levels may help identify individuals at greater risk of infection and inform more effective vaccination strategies.
Patients with Long COVID are using digital tools and online communities to track symptoms, identify patterns, and develop care plans. Despite medical dismissiveness, self-tracking data helps patients advocate for diagnostic tests and treatment.
Research found Covid infection may accelerate blood vessel aging around five years, especially in women, leading to a higher risk of cardiovascular disease. The study included 2,390 participants from 16 countries and found stiffer arteries in all three groups of patients who had been infected with Covid.
A new study by Michigan Medicine University of Michigan researchers concludes that broad COVID-19 vaccination in adults saves the US more money than it spends, with significant economic benefits for those over 65 and middle-aged adults. The model focuses on preventing deaths, hospitalizations, and lost productivity.
A synthetic glycosystem mimics natural sugars on human cells, binding to virus's spike protein and preventing infection. The molecule was found to be effective at low doses and worked against multiple SARS-CoV-2 strains.
A modeling study finds that COVID-19 vaccination is more cost-effective for individuals aged 65 and above, with favorable results across different parameter input scenarios. The study's findings support the Advisory Committee on Immunization Practices' decision to recommend vaccination with the 2023-2024 mRNA vaccines.
Researchers discovered that subtle differences in molecular structure can significantly affect mRNA-based drug performance. The study found that optimizing stereoisomers of ionizable lipids like ALC-315 could lead to safer vaccines, as the (S,S)-form delivers mRNA efficiently with reduced toxicity.
A survey of over 1,600 US adults found that most know the negative impacts of smoking and drinking during pregnancy, but uncertainty exists around vaccines and weight gain recommendations. The majority are unsure about recommended vaccines for pregnant individuals, with a notable drop in knowledge since last year.
A nationwide cohort study of 1 million adults found no increased risk of 29 adverse events after vaccination with the updated COVID-19 mRNA vaccine containing the SARS-CoV-2 Omicron JN.1 lineage. The study provides reassuring safety data on the new vaccine, which has been widely adopted in response to the Omicron variant