Researchers used snail shells to recreate prehistoric cyclones in South East Queensland, Australia, by analyzing growth rings and stable isotopes. The study showed that snails responded to extreme rainfall events, not annual wetness, providing a new climate archive for the region.
Researchers developed a sulfosuccinic acid-enabled interfacial field chemistry strategy to regulate Zn anodes, enabling highly reversible Zn deposition. The optimized electrolyte achieved high Coulombic efficiency and long cycle life, making it suitable for fast-charging and deep Zn utilization.
Researchers developed a novel Si/a-Sn/CoSi2/G/C nanocomposite anode with a hierarchical, multifunctional matrix architecture, achieving simultaneous optimization of electronic conduction, mechanical robustness, and elastic stress recovery without sacrificing practical manufacturability. The anode delivers high reversible capacity, exce...
Professor Shin's research focuses on developing tissue-adhesive, electrically conductive hydrogels for muscle and brain tissue repair. Her AYSF-supported project aims to engineer an injectable hydrogel filler for brain tumor recovery, addressing the limited capacity for neural tissue regeneration in the adult brain.
Researchers developed a nanomedicine that combines photothermal therapy, STING activation, and immune checkpoint blockade to convert
Researchers developed an AI-guided laser technique to carve micro-pyramids for robots to sense soft surfaces gently. The technique enables the creation of flexible conductive skins with high sensitivity and linearity, outperforming conventional designs.
Soil bacteria, particularly plant growth-promoting rhizobacteria, effectively degrade herbicides and petroleum hydrocarbons through rhizoremediation. This process involves the release of organic compounds from plant roots, which feed bacteria that break down pollutants.
University students accumulate less daily physical activity and more sedentary time than older adults, with significant public health implications. The study highlights the need to rethink public health messaging and redesign urban environments to promote incidental movement in younger generations.
Researchers found that the river has not settled into a stable state, with species disappearing and new ones arriving, despite 23 campaigns of monitoring
Researchers identified ANKRD11 as a key regulator that suppresses CD8+ T cell activity during chronic hepatitis B virus infection and cancer. ANKRD11 deficiency reprograms CD8+ T cell differentiation to enhance immunity in chronic infection and cancer, making it a potential therapeutic target.
Researchers used AI to study the relationship between strain and charge mobility in molecular single crystals, revealing how stretching affects their electrical performance. The study's findings contribute to the design of robust organic crystals for wearable applications.
Marine carbohydrates have shown antiviral, anticoagulant, immunomodulatory, and antitumor activity, with potential applications in drug delivery, wound healing, and tissue engineering. Further research is needed to establish reliable production methods and improve structural and activity-based quality control.
Researchers found that m6A, a small chemical modification on RNA, acts as a molecular delivery tag to transport specific RNAs to distant regions of neurons. The study provides a basis for investigating RNA delivery errors in brain disorders and may inform the development of new therapeutic strategies.
The REZILIENT 3 trial found a six-month improvement in median progression-free survival with the combination of zipalertinib and platinum-pemetrexed chemotherapy. The study showed a 50% reduction in disease progression or death and a substantially higher response rate compared to chemotherapy alone.
The Phase 3 DESTINY-Lung04 trial showed that trastuzumab deruxtecan significantly improves progression-free survival in patients with HER2-mutant non-small cell lung cancer, with a median PFS of 14.3 months compared to 8.3 months with pembrolizumab plus chemotherapy. T-DXd also demonstrated a higher objective response rate and better d...
The eight-year ADAURA update reports a significant overall survival benefit with adjuvant osimertinib in patients with completely resected, EGFR-mutated stage IB-IIIA NSCLC. The study found an eight-year overall survival rate of 74% with osimertinib versus 58% with placebo.
The PAPILLON study demonstrates the longest overall survival for patients with EGFR exon 20 insertion-positive advanced NSCLC using first-line amivantamab-chemotherapy. The study found a median overall survival of 34.3 months with amivantamab-chemotherapy versus 27.9 months with chemotherapy.
The ARROS-1 trial revealed a 94% objective response rate and 94% nine-month duration-of-response rate among TKI-naive patients with advanced ROS1-positive NSCLC. Intracranial activity was also notable, with a 100% intracranial objective response rate and 78% 12-month intracranial duration-of-response rate.
The European Society of Endocrinology is urging policy action to address a widening gap between care demand and workforce capacity. The endocrine workforce faces significant stress, burnout, and limited time for research, threatening timely and high-quality care.
A survey of 17 G20 countries found that 65% of respondents believe the economic system is rigged to favor the rich and powerful, while 69% want major changes. However, only 31% trust their government to make decisions that benefit the majority in the long term.
A large study found that people exposed to higher levels of air pollution face a higher risk of developing glaucoma and cataract. The study suggests that fine particulate matter is a key contributor to these risks, and that reducing air pollution can help prevent these eye diseases.
A new US Medicare pricing policy could reshape global pharmaceutical markets, potentially driving up prices and delaying medicine launches worldwide. The study estimates that Medicare could save $5.2 billion under its initial phase, with savings rising to $21 billion if expanded to all Medicare beneficiaries.
A new study reanalysed data from eight randomised trials on mammography screening, finding overdiagnosis to be less than 5%. The researchers suggest that previous high estimates of overdiagnosis were based on incomplete evidence and taken out of context.
Researchers developed a low-cost smartphone attachment to capture diagnostic-quality eye images, which can be reviewed remotely by ophthalmologists. Community health workers and remote ophthalmologists agreed on 96% of cataract diagnoses, challenging the assumption that specialist presence is necessary for accurate screening.
A study investigated the effects of space exposure on intraocular lenses and surgical equipment, finding that most lenses showed no notable damage after a six-month orbital journey. The research aims to develop better packaging, shielding, and material selection strategies for space missions, as the cost of sending equipment to space i...