About The Study: The findings from this study project that climate change may substantially increase heat-attributable cardiovascular disease burden across the U.S. by 2050, disproportionately affecting economically vulnerable populations and population aging amplifying this impact. The Pacific Northwest showed highest baseline burden, while Southern and Midwestern states demonstrated steepest projected increases. Heat mitigation must become central to cardiovascular prevention, with targeted interventions prioritizing vulnerable communities. The study analyzed 3,108 U.S. counties from 2010 through 2016 with projections in 2030 and 2050.
Corresponding Authors: To contact the corresponding authors, email Sanjay Rajagopalan, MD, ( sanjay.rajagopalan@uhhospitals.org ) and Salil V. Deo, MD, PhD, ( svd14@case.edu ).
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(doi:10.1001/jamacardio.2026.1240)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
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JAMA Cardiology