A study involving 69 people, 36 of whom had received a diagnosis of obsessive-compulsive disorder (OCD), finds that conflict-related activity in 36 brain regions, including the default mode network, during a spatial conflict task predicted which of the individuals with OCD would respond well to exposure-based psychotherapy; the results suggest both a personalized approach to treating OCD and additional insights into the neural activity underlying OCD.
Article #19-09199: "Task-based fMRI predicts response and remission to exposure therapy in obsessive-compulsive disorder," by David Pagliaccio et al.
MEDIA CONTACT: David Pagliaccio, Columbia University Medical Center, New York, NY; e-mail: david.pagliaccio@gmail.com
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Proceedings of the National Academy of Sciences