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Five-year absolute risk–based and age-based breast cancer screening in the US

01.20.26 | JAMA Network

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About The Study: In this decision analytical modeling study of breast cancer screening, population risk-based screening using 5-year invasive breast cancer risk was associated with similar or greater benefits than age-based screening as well as reduced false-positive recalls. As personalized medicine advances, risk-based screening is poised to become a cornerstone of breast cancer prevention, offering a more nuanced and tailored approach to patient care.

Corresponding Author: To contact the corresponding author, Oguzhan Alagoz, PhD, email alagoz@engr.wisc.edu .

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.52944)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open : JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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How to Cite This Article

APA:
JAMA Network. (2026, January 20). Five-year absolute risk–based and age-based breast cancer screening in the US. Brightsurf News. https://www.brightsurf.com/news/L59Z6DR8/five-year-absolute-riskbased-and-age-based-breast-cancer-screening-in-the-us.html
MLA:
"Five-year absolute risk–based and age-based breast cancer screening in the US." Brightsurf News, Jan. 20 2026, https://www.brightsurf.com/news/L59Z6DR8/five-year-absolute-riskbased-and-age-based-breast-cancer-screening-in-the-us.html.