About The Study: In this population-based cohort, 1-year mortality after an emergency department visit for an opioid overdose was 8.6%, and 21.2% of individuals experienced a repeat opioid overdose. Mortality was higher than estimates from previous research conducted prior to the widespread availability of fentanyl (5.3%-5.5%), although differences in cohort definitions may contribute.
Corresponding Author: To contact the corresponding author, Robert A. Kleinman, MD, MSc, email robert.kleinman@camh.ca .
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(doi:10.1001/jama.2026.6469)
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