About The Study: In the Chronic Kidney Disease Prognosis Consortium, 11% of outpatient participants and 35% of hospitalized patients had a cystatin C–based estimated glomerular filtration rate (eGFRcys) that was at least 30% lower than their creatinine-based eGFR (eGFRcr). In the outpatient setting, presence of eGFRcys at least 30% lower than eGFRcr was associated with significantly higher rates of all-cause mortality, cardiovascular events, and kidney failure.
Corresponding Authors: To contact the corresponding authors, email Morgan E. Grams, MD, PhD ( Morgan.Grams@nyulangone.org ) and Josef Coresh, MD, PhD ( ckdpc@nyulangone.org ).
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(doi:10.1001/jama.2025.17578)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being presented at the American Society of Nephrology Kidney Week 2025 meeting.
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