Articles tagged with Cardiovascular Disorders
A telemedicine-based management programme improved quality of life and self-care in patients with heart failure, with clinically relevant improvements in health status and symptoms. The programme demonstrated high patient satisfaction and adherence to daily habits, such as medication intake and physical activity.
Researchers developed machine-learning models to predict mortality in patients after a type of heart attack, known as STEMI. The models, called PERISCOPE, outperformed existing scores in predicting in-hospital and six-month mortality rates.
A study found that having an older AI-estimated heart age compared to actual age is associated with worse cardiovascular and dementia-related death outcomes. The research used deep learning AI models to estimate heart age from ultrasound images and analyzed data from a community-based cohort of 568 adults. The results showed a signific...
Researchers at Washington University in St. Louis have developed the first human model for desmin-related cardiomyopathy (DRM), a familial disease affecting approximately 1 in 2,000 individuals worldwide. The engineered tissue model allows for the study of protein aggregation and misfolding, which is thought to contribute to the diseas...
Researchers at Penn State will test whether a remote program focused on gardening, cooking, nutrition education, and peer support can help adults build healthier habits and influence their children's health. The program aims to combine enjoyment and intrinsic motivation for sustained behavior change.
Researchers have successfully prevented the development of severe heart failure in a mouse model by blocking a protein that triggers excessive scar tissue. Lowering AEBP1 levels after a heart attack or prolonged hypertension could be a valuable therapy to prevent or slow down heart failure progression.
According to a new American Heart Association scientific statement, fewer than 5% of US military veterans may achieve optimal cardiovascular health. The statement highlights military veteran-specific risks and strategies to improve cardiovascular health and longevity. Practical opportunities to improve lifestyle behaviors, cardiometabo...
Researchers found that high levels of BNP hormone directly activates platelets, leading to blood clot formation and blockages. This discovery provides a biological explanation for the increased risk of cardiovascular events in patients with high BNP levels.
Cardiologist George Dangas, MD, PhD, is recognized for his lifetime achievements in caring for patients and cardiology education. He is the third interventional cardiologist from Mount Sinai to receive the Laennec Master Clinical award, which celebrates his exceptional insight in correlating cardiovascular disease with clinical findings.
Scientists have developed a treatment that 'reawakens' heart muscle cells, promoting repair and improving heart function after a heart attack. The treatment, using mRNA therapy, temporarily activates proteins that help regenerate heart tissue, leading to a stronger heartbeat and increased blood pump efficiency.
Researchers found that intravenous cangrelor improved heart function in cardiogenic shock patients, with a 73% lower risk of microvascular obstruction compared to oral ticagrelor. After one year, cangrelor patients showed a significant increase in heart pumping ability, outperforming ticagrelor.
The Society for Cardiovascular Angiography & Interventions (SCAI) has updated its cardiogenic shock classification to improve recognition and treatment response. The new framework emphasizes perfusion and patient trajectory, helping clinicians assess shock severity over time and determine if treatment is restoring adequate circulation....
A new $6.9 million grant from CIRM will support preclinical development of an investigational cell therapy for heart created by USC Stem Cell scientists. The treatment aims to heal cardiac muscle after a severe heart attack, with clinical trials targeting late 2027.
Women experienced clot reduction similar to men after aspiration thrombectomy, with similar short-term results in both groups. Despite higher pre-treatment risk, women showed comparable outcomes in terms of hospital stay and discharge status.
The annual number of TAVR procedures among patients younger than 70 rose from 15 in 2014 to 134 in 2024, with surgical aortic valve replacement remaining the predominant approach. TAVR was particularly popular among patients aged 60 to 69, with lower rates of acute kidney injury and bleeding compared to SAVR.
A new research project aims to identify rising cardiac arrest risk before it happens using artificial intelligence and multiple types of health data. The system will combine symptoms, activity tracker data, medical history, and blood tests to provide real-time risk updates.
A study found that heat waves and air pollution increase the risk of acute stroke in older adults in São Paulo, Brazil. Physical exercise and cardiovascular prevention are the best strategies for protecting the brain.
Researchers found that sotagliflozin reduces excessive platelet activation, a process that can lead to dangerous blood clots that block flow to the heart and brain. The drug also makes platelets less likely to stick together and form blood clots, potentially lowering the risk of heart attack and stroke.
A study published in the European Journal of Preventive Cardiology found that even a single session of heated tobacco use can cause measurable damage to blood vessels and DNA damage in healthy smokers. Blood vessel function decreased by 11% and systolic blood pressure increased by 3mmHg after use.
Henry Ford Health has enrolled the first US patients in a clinical trial evaluating pulmonary artery denervation, a treatment for pulmonary hypertension related to heart disease. The trial aims to determine the safety and effectiveness of the investigational treatment.
A new study found that higher fish intake before and during pregnancy was associated with lower odds of certain forms of hypertensive disorders of pregnancy. Women in the highest fish-intake group before pregnancy had 34% lower odds of early-onset HDP.
Admissions for atrial fibrillation, heart failure, and heart attack rose faster in Western US states with legal cannabis sales, with faster rates for atrial fibrillation (2%), heart failure (4%), and heart attack (3%)
A study found that regular tea consumption was linked with an 11% lower risk of cardiovascular disease, with the lowest risk estimated at approximately 6–8 cups per day among weekly drinkers. Black tea showed more consistent inverse associations with vascular disease than green tea.
Gene therapies can already change clinical care, but their use in common conditions raises concerns about permanent harm and competition with existing treatments. Cardiologists propose strategies for determining when genomic therapy is justified, including considering the benefits, risks, and long-term safety monitoring.
A study by George Mason University researcher Kyeung Mi Oh found that caregivers' sleep, physical functioning, and emotional well-being are key factors associated with caregiving burden and psychological distress. The research highlights the importance of recognizing caregivers' health needs and providing tailored support to mitigate t...
The EXIT-CVD project seeks to improve cardiovascular care through interventions at 3 key exit points: preventing and detecting disease before it develops, reversing disease progression, and halting progression and stimulating recovery. The project includes 22 clinical studies across 17 European countries, with a focus on equity and co-...
A new study at UT Arlington uses AI to reduce radiation exposure in heart scans without sacrificing diagnostic accuracy. The project, led by Mingwu Jin, aims to substantially lower radiation doses using deep learning-based reconstruction methods.
Heart failure alters the bone marrow, reducing protective cells that regulate inflammation, reports a study conducted at Science Tokyo. The bone marrow niche is found to play an important role in transmitting the effects of cardiac stress to blood cell forming stem cells.
A new treatment using drug-coated balloons performed just as well as conventional stents in preventing heart attacks and cardiovascular deaths. However, patients treated with drug-coated balloons were more likely to need a repeat procedure in larger arteries.
Researchers found that applying biomechanical tension to heart valves every time they beat helps protect collagen from breaking down, explaining why leaflets remain sturdy for decades. Increasing strain while preserving the natural strain ratio prevents collagen degradation, highlighting a biomechanical defense mechanism.
A new analysis of US national health data found that inflammation increases across the stages of cardiovascular-kidney-metabolic syndrome, with the largest increase at the earliest stage. Average hs-CRP nearly doubled between stage 0 and stage 1, crossing the 2 mg/L threshold commonly used to signal increased cardiovascular risk.
The American Heart Association has selected 5 finalists for its 2026 Health Tech Competition to advance solutions for heart and brain health. The finalists will present their market-ready technologies at Scientific Sessions 2026 in Chicago, with a focus on improving cardiovascular and brain health outcomes.
Researchers identified three key particles that contribute to heart disease risk after 'bad' cholesterol is lowered, including triglyceride-rich lipoprotein and lipoprotein(a). The study suggests that measuring or targeting these particles may improve prevention alongside existing treatments.
Researchers at Johns Hopkins University have created tiny robots called 'millirobots' that can deliver medicine directly to infected heart tissue, reducing treatment time from weeks to just hours. The robots use magnetic guidance and are designed to replace open-heart surgery and ineffective IV-drug therapy.
A study by researchers at Georgia State University found that chronic intestinal inflammation can drive cardiac dysfunction through changes in gut microbiota and immune cells. The study identified a bacterial component called lipopolysaccharide as an important link between the gut and heart.
Researchers have developed an affordable, open-source air quality monitoring device for wildlife, tracking particulate matter and providing insights into smoke exposure and behavior. The device can be attached to animal collars, filling gaps in data and delivering health insights for people exposed to smoke.
A major new report from the European Society of Cardiology outlines how health services can protect people with heart disease in heatwaves. The report provides practical guidance on preparing patients for extreme heat, managing medication, advising on hydration and cooling, and monitoring patients during hot weather.
Researchers found that well-designed digital alerts can assist clinicians in high-pressure situations, prompting them to make recommended treatment decisions and recognize when patients are deteriorating. The studies demonstrated the effectiveness of electronic health record alerts in the emergency department and cardiac intensive care...
A UK study found that women with pregnancy complications, including gestational diabetes and high blood pressure, face an elevated risk of developing cardiometabolic-renal conditions in subsequent years. The study, which followed over 1.4 million women, identified associations between postnatal depression and an increased risk of four ...
The European Cardiovascular Health Data and AI Network (CHAIN) aims to improve cardiovascular care through AI adoption. The initiative will build a federated ecosystem for the safe and effective adoption of AI and health data, enabling earlier disease detection and more consistent care.
A new study by Mass General Brigham researchers shows that a longer duration Food Is Medicine program associated with improved adult cardiometabolic health. Participants who received weekly plant-based grocery packages for 2.7 years showed dose-dependent reductions in diastolic blood pressure, body weight, and BMI.
Atrial fibrillation during sepsis is a common complication with no established treatment guidelines, linked to increased risks of stroke, death, and recurrence. The review highlights the need for a universally accepted definition, validated prediction models, and standardized anticoagulation strategies to manage this condition.
Mount Sinai has launched an international clinical trial to determine the optimal treatment for spontaneous coronary artery dissection (SCAD), a sudden tear in the wall of a heart artery that can reduce blood flow and cause an uncommon type of heart attack. The trial, known as SCAD-ALIGN, will compare a moderate antiplatelet strategy o...
A recent clinical trial led by Stanford Medicine shows that a new oral medication, acebilustat, effectively alleviated many symptoms of lymphedema, a condition characterized by excess lymph fluid accumulation. The study involved 23 participants with lymphedema, who took acebilustat for a year and experienced significant symptom relief.
Researchers are working on a four-year project to develop a personalized model that uses detailed blood flow information to detect obstructions in the aorta. The project aims to improve prenatal testing so that doctors can spot problems in the aorta before a baby is born and recommend treatments.
The first-ever EU Screening Week aims to detect risk factors earlier and prevent serious cardiometabolic diseases. Key health indicators like blood pressure, blood sugar, and cholesterol will be checked to take preventive action sooner.
Researchers at Sanford Burnham Prebys discovered that blocking an energy transfer enzyme shifts mammalian hearts into a regenerative state, promoting regeneration and improving recovery after a heart attack. By modulating heart cell metabolism, scientists can potentially awaken the heart's dormant regenerative abilities.
Researchers found a 44% lower risk of death from any cause after one year and 35% lower risk after two years among type 2 diabetes patients starting continuous glucose monitoring. CGM use also showed a reduced risk of cardiovascular events, including heart attack and stroke.
A new study found that drones can significantly reduce the time between cardiac arrest reporting and defibrillation, particularly in rural and congested areas. By combining fixed AEDs with drones, access times can be reduced by up to 3.76 minutes, with over 95% of cases covered within five minutes.
A new blood test and scoring system could reduce hospital visits for patients with chest pain by up to 34% by triaging them at home or to their general practitioner. The study found that 165 patients out of 483 assessed by ambulance crews using the test and scoring system were left at home, compared to 19 out of 539 without the test.
Researchers identified a common signaling pathway activated by three adenosine receptor subtypes, leading to cardiac fibroblast activation and scarring. Blocking these receptors together produced a stronger antifibrotic effect, suggesting a potential therapeutic target for heart disease.
A new study suggests that semaglutide reduces heart disease risk beyond just weight loss, but the exact mechanism is unclear. The study analyzed data from a clinical trial of semaglutide, which found that patients taking the drug had a 20% lower risk of heart disease, but only half of this reduction could be explained by changes in kno...
A new study aims to find new ways to prevent strokes in people with chronic migraine by understanding the link between cardiovascular and cerebrovascular health. The research also explores the role of immune cells in blood vessels and their impact on migraine attacks.
A study found that adolescents with a high body mass index may age biologically faster, increasing their risk of developing obesity-related diseases and premature death. The study's findings suggest a link between genetic predisposition to high BMI and accelerated biological aging.
Exercise-based cardiac rehabilitation reduces hospital admissions by a third and heart attack risk by more than a quarter, with long-term benefits and cost-effectiveness. Digital programmes can be just as effective as traditional centre-based services, making rehabilitation more accessible.
A new study has found a significant link between Long COVID and POTS, with nearly two-thirds of Long COVID participants meeting the diagnostic criteria for POTS. The study suggests that POTS may be contributing to symptoms such as dizziness, fatigue, and brain fog in some individuals with Long COVID.
New models predict enhancer-gene interactions from single-cell data, enabling accurate mapping across cell types. The models use CRISPR experiments to train, performing well on datasets of varying sizes and sequencing depths. This breakthrough charts enhancer-gene regulation across thousands of cell types.
A systematic review and meta-analysis of 87 clinical trials found that consuming four to six servings of wholegrain per day can lower cardiovascular risk factors, including body weight, waist circumference, and total cholesterol levels. Benefits were most pronounced at intakes of 60 to 100 grams per day.
A new study by Michigan Medicine found that heart surgery infection rates vary significantly across U.S. hospitals, with some experiencing nearly double the risk of others. By reducing infections, hospitals could prevent 2,600 infections and reduce Medicare spending by $441 million annually.
A nationwide study found that lower temperatures are a significant risk factor for cardiac arrests, with a daily temperature drop of over 5°C serving as a warning signal. The study developed a predictive model using meteorological data to estimate expected daily numbers of cardiac arrests up to 3 days in advance.