Cardiovascular Disorders
Articles tagged with Cardiovascular Disorders
Prior heart attack linked to faster declines in thinking and memory skills
Global hypertension study finds fight against high blood pressure falling short
Perimenopause may offer a “window of opportunity” for heart disease prevention in women
Patients with congenital heart defects are more likely to suffer a heart attack at an earlier age
Results of major heart study set to save lives, reduce unneeded heart implants
Heart scan and blood test improve risk prediction for inherited heart condition, major study finds
A large prospective study found that incorporating imaging and blood biomarker data into risk assessment improves prediction of adverse cardiac events in people with hypertrophic cardiomyopathy. The study used clinical history, cardiac MRI, and blood biomarkers to predict outcomes, providing fuller and more accurate predictions.
Researchers develop innovative model for risk assessment for hypertrophic cardiomyopathy
A new model for predicting outcomes in hypertrophic cardiomyopathy has been developed by incorporating prospective data, including clinical history, imaging, and blood biomarker tests. This study found that integrating these methods into risk assessment can improve the prediction of fatal and nonfatal cardiac events.
‘Lemon-on-sticks’ phenotype indicates poor prognosis in heart failure
Researchers found a high-risk subgroup of patients with the 'lemon-on-sticks' phenotype, characterized by low BMI and high WHR, who had poor outcomes and higher all-cause mortality rates compared to other phenotypes. This study highlights the need for personalized therapy in heart failure.
New positive data on old drugs: Digitalis reduces heart failure events
Researchers found that low-dose digoxin and digitoxin reduced worsening heart failure events in patients with mild-to-moderate heart failure and reduced ejection fraction. The treatment was generally well-tolerated and safe, offering a cheap and effective option for managing the condition.
Efficacy and safety of digitalis glycosides in heart failure
Large-scale Nordic study discovers link between polycystic ovary syndrome and heart disease
Cardiovascular and metabolic diseases are primary drivers of excess US deaths compared to other high-income countries
Limit ultra processed foods to lower risk of heart disease, say experts
A European Society of Cardiology consensus report suggests that ultra processed food consumption is linked to cardiovascular disease and death. The report calls for doctors to advise patients on limiting UPF intake to prevent cardiovascular risks.
Both very low and very high heart rates are significantly associated with stroke risk, novel study finds
A new study suggests that both very low and very high resting heart rates are associated with an increased risk of stroke. The research found a U-shaped pattern, with stroke risk lowest at heart rates of 60-69 bpm and highest at below 50 bpm or above 90 bpm.
Hidden muscle fat poses danger to heart, metabolism
Researchers used MRI to analyze muscle composition in 11,348 participants and found that higher intermuscular fat and lower muscle mass were associated with increased cardiometabolic risk factors. Lean muscle mass was only protective against these risks in men, while women's muscle mass declined after age 40.
TCT 2026 Career Achievement Award to be presented to Patrick T. O’Gara, MD
Patrick T. O'Gara, a master clinician and educator, will receive the TCT 2026 Career Achievement Award for his groundbreaking work in interventional cardiology. The award recognizes his clinical excellence, pioneering research, and mentorship of the next generation of physicians.
Distinct metabolic signature found in HFpEF
Researchers identified a unique metabolic fingerprint in the hearts of patients with heart failure with preserved ejection fraction (HFpEF) and obesity. The study reveals disrupted glucose metabolism and accumulated metabolic products, which are linked to structural changes in the heart and disease severity.
AI model analyses body composition to predict health risks
A study published in Radiology used AI to analyze whole-body MRI scans from over 66,000 participants, revealing that skeletal muscle quality is a strong predictor of diabetes, major cardiovascular events, and mortality. The researchers also found that high visceral fat and low skeletal muscle were associated with increased risks of the...
Maintaining a healthy heart may require regular doses of positivity
A recent study found that positive psychology interventions such as mindfulness and gratitude journaling can consistently improve blood pressure and inflammation markers within weeks. The researchers suggested that ongoing reinforcements are necessary to stay on course for long-term benefits.
High-intensity interval training shows strongest vascular benefits in cardiovascular patients
High-intensity interval training shows strongest vascular benefits in cardiovascular patients. HIIE consistently improves flow-mediated dilation and vasodilation, with combined high-intensity programs showing the largest estimated effects on endothelial function.
Cold hands, warm heart — Body temperature a key factor in where TRPM4 mutations cause disease
Researchers discovered that body temperature plays a key role in which tissues are affected by TRPM4 ion channel mutations. The findings explain why disease-causing TRPM4 mutations lead to mutually exclusive conditions, such as severe skin diseases like PSEK and heart disorders like progressive familial heart block.
Blocking stress signals could limit harmful inflammation after heart attack
Researchers discovered that stress hormones trigger neutrophils to detach from blood vessel walls and travel to the heart, causing inflammation. Blocking these stress signals with beta blockers may prevent excessive inflammation and improve heart healing.
Blood tests taken years earlier linked to pregnancy risk
A new study from Karolinska Institutet found that small abnormalities in blood sugar, lipids, and inflammation years before pregnancy are associated with an increased risk of high blood pressure during pregnancy and pre-eclampsia. The findings may contribute to earlier risk assessment and preventive measures.
GLP-1 drugs have long-term benefit for heart health
A new review found that GLP-1 weight-loss drugs significantly reduced the risk of heart attacks, strokes, and premature death. The treatment also lowered rates of non-fatal heart attacks, hospital admissions for heart failure, and deaths from any cause.
Methamphetamine use linked to 1 in 6 heart attacks in California study
A new study published in the Journal of the American Heart Association found that methamphetamine use accounted for nearly 15% of heart attacks in a northern California study. People who suffered meth-related heart attacks were often young- to middle-aged men without traditional heart disease risk factors, highlighting the need for spe...
Plant-based eating may reduce inflammation, new research suggests
A study published in Nutrition, Metabolism and Cardiovascular Diseases found that plant-based dietary patterns were associated with significantly lower C-reactive protein levels compared to omnivorous diets. This reduction may indicate less background inflammation and lower cardiovascular risk.
Validation study from Mass General Brigham reveals new tool can predict patients’ genetic risk of eight cardiovascular conditions
Researchers developed a new polygenic risk score (PRS) that estimates a person's inherited risk for eight common cardiovascular conditions. The test combines information from many genetic variants and evaluates a person's risk for coronary artery disease, atrial fibrillation, type 2 diabetes, and more.
Second call for entries: Applications still open for the 2026 Semmelweis–Richter journalism Award
The 2026 Semmelweis-Richter Journalism Award is now open for entries, with a focus on high-quality health journalism and its impact across Europe. Journalists can submit articles in two categories until June 9, 2026, with a total prize fund of €45,000.
As heart, kidney and metabolic health worsen, cancer risk may rise
A new study published in Circulation: Population Health and Outcomes journal links cardiovascular-kidney-metabolic syndrome to a higher risk of developing cancer. The study found that individuals with advanced heart, kidney, and metabolic disease face a sharper increase in cancer risk only in the later stages of CKM syndrome.
University of Cincinnati works with local paramedics to advance sudden cardiac arrest research
A University of Cincinnati study proves the feasibility and scalability of collecting blood from patients in cardiac arrest during treatment. The approach, which involves paramedics delivering samples to a biorepository, showed significant variation among patients and underscores the need for further research.
Genetic study finds new pathways involved in cardiometabolic disease
A study published in PLOS Medicine has identified two new genetic pathways contributing to cardiometabolic disease, including heart disease and obesity. The research analyzed lipid metabolites and their link to disease, suggesting that targeting specific metabolic pathways could prevent or lower the risk of disease.
Worcester Polytechnic Institute researchers seek to uncover the path to heart valve failure
Researchers aim to determine the connection between circulating lipoprotein (a) and calcific aortic valve disease, with a focus on biomechanics and early detection. They will also explore how mechanical forces influence disease progression and treatment.
Ischemic heart disease burden declines in rate but rises in number
The study found a decline in age-standardized incidence rates for ischemic heart disease (IHD) in high-income countries, but a rapid rise in burden due to the increasing number of older adults and a growing global population. The total number of incident IHD cases is expected to continue rising until 2030.
Scientific researchers awarded $15 million to study heart valve disease
A new $15 million research network will investigate the causes and treatments of heart valve disease, which affects over 80 million people worldwide. The American Heart Association hopes to develop early warning signs and diagnosis methods to expand treatment options and improve quality of life for patients.
Approximately half a million post-9/11 U.S. veterans had high blood pressure
A CDC study found that approximately half a million post-9/11 U.S. veterans had high blood pressure, highlighting the need for early prevention strategies. The study also revealed that Black veterans were more likely to have high blood pressure and women were often undiagnosed.
Low-dose triple-pill cut risk of recurrent stroke by about 40%, global trial shows
A global trial involving 1,670 patients with intracerebral haemorrhage found that treatment with a single pill combination of three low-dose blood pressure medicines reduced the risk of another stroke by 39%. The study showed significant benefits in reducing major cardiovascular events and improving blood pressure control.
Top 3 dietary risks behind 5.9 million heart deaths globally
A comprehensive study reveals that high sodium intake, low fruit consumption, and lack of whole grains are the primary drivers behind 5.9 million cardiovascular deaths worldwide. Researchers emphasize the need for targeted policy interventions, such as mandatory front-of-pack labeling and food reformulation in high-population countries.
Chinese Medical Journal article review explores artificial intelligence in heart failure management
A recent review highlights how AI enables precision treatment, continuous monitoring and individualized prognostic modeling for heart failure patients. AI integrates large-scale structured electronic health records and multimodal imaging to characterize cardiac structure and function, enhancing diagnostic accuracy.
Cardiac CT scans see the future: Visualizing "invisible" heart risks
Researchers at Kumamoto University discovered that combining cardiac Computed Tomography (CT) scan markers can identify patients at highest risk for future heart failure and death. The 'delayed phase' scan detects localized scarring and subtle damage throughout the heart muscle, providing a synergistic view of heart health.
Redo surgical mitral valve replacement shows long-term survival advantage over transcatheter valve-in-valve
A new multicenter study finds that reoperative surgical mitral valve replacement demonstrates significant long-term survival benefits over transcatheter mitral valve-in-valve procedures in patients with failing bioprosthetic valves. At five years, rSMVR patients had lower mortality and more favorable valve performance.
Excessive napping may be a warning sign of underlying or developing health conditions in older adults
A study of 1,338 older adults found that longer, more frequent, and morning naps were associated with higher mortality rates. Excessive daytime napping was linked to increased risk of neurodegeneration, cardiovascular diseases, and greater morbidity.
Study points to new treatment target for fatal infant heart disease
Researchers at Keck School of Medicine have identified a new potential treatment target for AARS2-related cardiomyopathy, a rare and fatal heart muscle disease in infants. By targeting the PCBP1 gene, they aim to restore healthier AARS2 function in heart cells and prevent damage.
Karina Yaniv begins professorship at HI-TAC, Mannheim
Dr. Karina Yaniv has been appointed as the new Scientific Director of Systemic AngioCardioScience at the Helmholtz Institute for Translational AngioCardioScience (HI-TAC). She aims to expand her research with a focus on translation into clinical applications, and build a bridge between basic and translational cardiovascular research.
Loneliness linked to increased risk of degenerative heart valve disease
A large-scale study linked loneliness to an increased risk of degenerative heart valve disease, including aortic valve stenosis and mitral valve regurgitation. Researchers say addressing loneliness could help delay disease progression and reduce the clinical and economic burden of valvular heart disease.
Images and risk communication boost motivation for better heart health
A study from Umeå University found that visualizing ultrasound images of atherosclerosis, combined with a motivational dialogue, increases motivation to improve lifestyle habits and take preventive medication. This results in lower estimated risk of cardiovascular disease and better development of risk factors over time.
As syphilis cases rise, study links infection with higher risk of stroke, heart attack and other serious cardiovascular problems
A study from Tulane University found that long-term, untreated syphilis increases the risk of serious cardiovascular issues, including stroke, heart attack, and aortic aneurysm. Adults with syphilis were more likely to develop these problems than similar patients without the infection.
Timing exercise to match body clock chronotype may lower cardiovascular disease risk
Research suggests that exercising at a time that matches an individual's natural chronotype (morning or evening alertness) can lower cardiovascular disease risk. The study found that chronotype-aligned exercise improved blood pressure, fasting glucose, cholesterol levels, and sleep quality more effectively than mismatched timing.
New data on effective cardiac resynchronisation in patients with heart failure
A randomized trial demonstrated that Left Bundle Branch Area Pacing (LBBAP) is an effective strategy for cardiac resynchronisation in patients with heart failure. LBBAP was found to reduce device-related complications and procedure times compared to biventricular pacing.
American Heart Association backs new research that could transform cardiac outcomes for hundreds of thousands of Americans
Researchers have identified a critical molecular mechanism that shuts down the heart's repair system after cardiac arrest, leaving it unable to recover. The study aims to develop new treatments for devastating medical conditions such as heart attack and stroke during major surgery.
Better use of exercise time? Adding resistance training improves strength and aerobic fitness beyond aerobic exercise alone in heart failure
Combining resistance training and aerobic exercises significantly enhances aerobic fitness, muscle strength, and walking distance in heart failure patients. Adding resistance training to aerobic workouts increases muscle strength more than exercising aerobically alone.
Early weight gain is linked to lifelong health consequences
A study of over 600,000 people found that early weight gain is associated with a higher risk of dying from various diseases, particularly cardiovascular disease and type 2 diabetes. Weight gain during adulthood also increases the risk of premature death, especially for those who develop obesity at a younger age.
Swelling after brain bleed linked to worse outcomes, study finds
University Hospitals Harrington Heart & Vascular Institute study highlights long term gains in cardiovascular outcomes at UH Portage Medical Center
A new study by University Hospitals Harrington Heart & Vascular Institute highlights the long-term impact of preventive heart and vascular care. The study shows a significant decline in cardiovascular mortality rates after investments in local cardiac care, with notable reductions among older age groups.
Study: How a new approach in community clinics helped low-income patients address high blood pressure
A team-based program in community health clinics helped low-income patients reduce their blood pressure more than standard care alone. After 18 months, patients in the team-based program saw a significant drop in systolic blood pressure and showed better adherence to hypertension treatment.
Self-employed Hispanic women may be at lower risk for cardiovascular disease compared with their salaried counterparts
Research published in Ethnicity & Disease found that self-employed Hispanic women report less high blood pressure, obesity, and poor health compared to their salaried counterparts. They were also more likely to exercise, with a nearly 11% higher rate of physical activity.
Researchers predict coronary heart disease in diabetes subgroup
A new study by Lund University researchers found that genetic risk scores can predict coronary artery disease even before diabetes onset. The study identifies a group at high risk of developing both conditions, offering potential for early detection and prevention.
Research Spotlight: A new pulmonary embolism guideline, clinical advances and research updates, and a Mass General Brigham investigator’s insights
The new guidelines introduce five clinical categories to capture PE severity, emphasizing follow-up care and treatment considerations. Despite advances in diagnosis and treatment, PE remains a serious condition with substantial risk, highlighting the need for continued research and improvement.
The wearable ring on your finger could help assess your cardiovascular health while you sleep
Researchers developed a method to estimate vascular age from consumer wearables' PPG signals, predicting accurate results with a mean error of six to seven years. The technique uses a deep learning model and may lead to earlier detection of cardiovascular risk and more effective preventive care.
Small-volume hypertonic saline plus furosemide linked to lower inflammatory and remodeling markers in acute heart failure
Treatment with i.v. furosemide plus HSS significantly decreased serum levels of inflammatory biomarkers IL-6, sST2, hsTnT, galectin-3, and NT-proBNP. The study found that this combination therapy modulated some miRNA expression and was associated with reduced miR181b expression compared to furosemide alone.