A study found that environmental tobacco smoke exposure is linked to significant declines in reading and math scores, as well as logic and reasoning skills in children. The research suggests that even low levels of exposure can have adverse effects on cognitive abilities, with an estimated 33 million US children at risk.
Researchers tested a weakened version of herpes simplex virus against neuroblastoma tumors, with only the virus proving effective in treating the cancer. The study shows promise for using the therapy in children and potentially in other cancers as well.
Researchers have discovered that morphogen molecules move across cells via diffusion, a finding that could lead to new strategies for treating organ defects and cancers. The study used the fruit fly model to demonstrate how TGF beta family molecules function as morphogens.
Researchers have identified Foxa2 as a master gene controlling lung development and function at birth. The absence of Foxa2 leads to respiratory distress syndrome and death, highlighting its crucial role in stabilizing surfactant production.
Two studies published in Science suggest that eosinophils play a crucial role in the development of asthma, but the exact mechanisms are not yet clear. The findings challenge previous theories and highlight the importance of considering individual genetic factors in treating asthma.
Eosinophilic esophagitis (EE) is a rapidly rising disorder characterized by severely elevated levels of eosinophils in the esophagus, leading to vomiting and difficulty swallowing. The disease has a familial pattern suggesting genetic or environmental factors, warranting further study.
A new study led by Cincinnati Children's Hospital Medical Center found that imagining a favorite place reduced pain in children after surgery. The study used audio tapes and video tapes to help children manage their anxiety and pain, suggesting a potential multi-faceted approach to pain management.
A new study finds that a father's mental health has a significant impact on a child's behavioral and emotional problems, especially if the mother is struggling with depression. The research suggests that emotionally healthy fathers can substantially reduce the negative influence of a mother's poor mental health.
Researchers discovered that inflammatory genes are activated and control bile duct obstruction in biliary atresia, a disease affecting up to 50% of children undergoing liver transplants. Blocking these inflammatory signals may prevent disease progression and increase long-term survival.
Researchers at Cincinnati Children's Hospital Medical Center have discovered a link between heart disease and neurodegenerative diseases. The study found that toxic protein clusters called beta-amyloids, associated with Alzheimer's disease, are also present in the hearts of patients with heart failure.
Researchers at Cincinnati Children's Hospital Medical Center have detected high levels of adiponectin in human milk, a protein that may help regulate body fat and reduce the risk of obesity. The study suggests that early exposure to this protein through breast milk could influence metabolic health later in life.
A new study by Cincinnati Children's Hospital Medical Center has identified a strain of E. coli as the cause of diarrhea in young children. The research, which used genetic technology, found that nearly 10% of children treated for gastroenteritis tested positive for enteroaggregative E. coli.
A Cincinnati Children's Hospital Medical Center study found a positive association between autism and immune system disorders, including respiratory and skin allergies. Autistic children were less likely to have asthma compared to their non-autistic peers.
A recent study by Cincinnati Children's Hospital Medical Center suggests that human milk can significantly reduce the risk of severe infections in extremely low birth weight infants. The research analyzed data from 1270 infants and found that those who received human milk had a lower incidence of sepsis compared to those who did not.
A Cincinnati Children's Hospital Medical Center team increased immunization rates in a specialty outpatient clinic from 41% to above 90%, exceeding national averages. The project used business-world strategies, including reminders and tracking systems, to address barriers and foster innovation.
A study found that equol, a natural metabolite from soy isoflavones, blocks the effects of DHT without altering testosterone levels, reducing prostate size in rats. This molecule may offer a treatment for BPH and prostate cancer, as well as promoting healthy skin and hair growth.
A Cincinnati Children's Hospital study found a deficiency in lipoxins, key regulators of inflammation, in children with cystic fibrosis. This discovery provides impetus for developing novel therapeutics to decrease lung inflammation.
A study published in Pediatrics found that children with migraines experience significant impairment in school functioning and emotional well-being. The researchers surveyed 572 children and adolescents, revealing that quality of life is negatively affected across all areas of functioning compared to healthy peers.
Researchers found that girls entering puberty with breast development are more likely to be obese by late adolescence. Additionally, earlier age of menarche is associated with increased risk of breast cancer.
Research breakthrough identifies 291 genes associated with asthma, opening up new avenues for treatment and diagnostic development. The study focused on the arginase pathway, which regulates critical processes involved in allergic reactions.
Low health-related quality of life scores among urban children could impact their educational success. The study found an association between health-related quality of life and school connectedness, suggesting that programs addressing mental and physical health needs can improve perceptions.
A new study by Cincinnati Children's Hospital Medical Center shows that leaving vernix on newborn skin can improve hydration, reduce scaly texture, and promote a faster decrease in pH. The researchers hope to develop a synthetic equivalent for use in various applications, including wound dressings and medication delivery systems.
Studies found that residential injuries accounted for nearly 15% of emergency department visits and 39% of unintentional injury visits between 1993 and 1999. Fatalities due to fires, submersions, or falls were common among young children, with African-American children facing disproportionately higher risks.
A new study by Cincinnati Children's Hospital Medical Center found that frequent school changes are an independent predictor of behavioral problems in children. The study involved 3,285 children between the ages of 5 and 14, who were more likely to experience behavioral issues if they attended multiple schools.
A recent study conducted at Cincinnati Children's Hospital Medical Center found that approximately one in five mothers who visited the pediatric emergency department or a well-child clinic had depression. The study also revealed that 76% of these mothers reported difficulty caring for their children due to their depressive symptoms.
A new study by Cincinnati Children's Hospital Medical Center has identified heart abnormalities in obese children, revealing significant differences in the function of their hearts. The study used tissue Doppler imaging to assess diastolic function, finding that the hearts of obese children were stiffer and less able to fill with blood.
A groundbreaking study by Dr. Jorge Bezerra at Cincinnati Children's Hospital Medical Center has identified a genetic underpinning to biliary atresia, the most common reason for liver transplant in children. The discovery points to a potential role of cytokines in driving an inflammatory response against the body's own tissues.
A new study published in the American Journal of Public Health found that a woman's level of education is the strongest predictor of whether she will smoke before, during, and after pregnancy. The study also discovered that women with higher levels of education had significantly lower smoking rates compared to those with lower educatio...
A new Cincinnati Children's Hospital Medical Center study found that thickening of the heart can develop as early as adolescence in women, with obesity being the main factor. The study also discovered significant racial disparities in left ventricular hypertrophy prevalence among young African American and Caucasian women.
A comprehensive study found that both prenatal and postnatal lead exposure were associated with increased antisocial behavior in children and adolescents. The researchers followed inner-city adolescents for over two decades, tracking blood lead levels and documenting delinquent behavior.
Researchers found that low-income mothers who experienced depression and/or obesity reported their preschool children watched an average of two hours of TV per day. Children exposed to these conditions spent less time outdoors. The study highlights the need for caregivers to examine how maternal well-being affects child activity levels.
A study published in Ambulatory Pediatrics reveals that playground injuries are more severe and common than previously thought, accounting for a significant proportion of emergency visits. The study found that children aged 5-9 years had the highest rates of emergency visits due to playground falls.
A new study by Cincinnati Children's Hospital Medical Center reveals that some children receive five times more radiation than necessary during CT scans. Researchers found that adjusting technical factors like tube current and pitch can significantly reduce exposure without sacrificing image quality.
A new study establishes a link between gastroesophageal reflux and allergies, including environmental allergens like pollens and molds. The discovery could lead to new treatments for children with eosinophilic esophagitis and adults with refractory reflux.
A study by Cincinnati Children's Hospital Medical Center found that only 21% of mothers of preschoolers feel their children are overweight, highlighting a significant misperception. Mothers with lower education levels were more likely to underestimate childhood obesity and have heavier children.
A study has identified four factors that contribute to decreased school connectedness, including declining health status, cigarette use, and lack of extracurricular involvement. School nurses may play a key role in identifying disconnected youth, who are at higher risk for adverse outcomes.
Researchers at Cincinnati Children's Hospital Medical Center have identified eotaxin as a critical protein in the development of food allergies. By blocking eotaxin, new drugs may prevent allergic reactions in the gastrointestinal tract, providing hope for those affected by food allergies.
A study conducted by researchers at Cincinnati Children's Hospital Medical Center shows that nearly 75 percent of children with severe juvenile rheumatoid arthritis respond dramatically to ENBREL (etanercept). The drug eases joint pain and swelling, enhances mobility, and improves disease activity for patients.
A study by Dr. Elizabeth Goodman found a significant association between socioeconomic status and depressive symptoms, obesity, and poorer ratings of overall health among teenagers. The research examined data from over 15,000 surveys and found that lower socioeconomic status was linked to higher rates of these chronic illnesses.
A study by Cincinnati Children's Hospital Medical Center found that early discharge for full-term, Medicaid newborns in Ohio did not result in increased rehospitalization rates. In fact, rehospitalizations decreased 23% due to better post-discharge coordination of care.
A new study found that residential dust control measures are not effective in reducing blood lead levels in children. Despite parents' best efforts, lead contamination remains a significant concern, and experts call for stricter housing standards to protect children.
Expert Bruce P. Lanphear argues that federal standards ignore existing scientific evidence and fail to protect inner-city children from lead poisoning. He proposes a primary prevention approach, focusing on eliminating residential lead hazards before exposure, to mitigate the harmful effects of low-level lead exposure.
Researchers at Cincinnati Children's Hospital Medical Center have found that cyclosporin can prevent hypertrophic cardiomyopathy (HCM) in rats and mice. This is an inherited form of heart disease affecting one in 500 individuals, characterized by cardiac hypertrophy.
Researchers have discovered a protein in bacteria that protects them from nitric oxide, a toxin produced by the immune system. This mechanism allows bacteria to survive and thrive, with implications for human health and the development of new antibiotics.