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European Society of Cardiology


Results of the ELISA II trial

The ELISA II trial found that triple antiplatelet (AP) therapy reduced enzymatic infarct size and improved epicardial coronary artery flow in patients with non-ST segment elevation acute coronary syndrome (NSTE ACS). Triple AP therapy also showed a trend towards better event-free survival at 96 hours and 30 days after randomization.

SIRIUS II trial

The SIRIUS II clinical trial demonstrated dose-dependent favorable hemodynamic effects and improvements in cardiac output and dyspnea score in patients with acute decompensated congestive heart failure (ADHF). Ularitide was well-tolerated, preserving kidney function during treatment.

Women at heart: Stop the bias

A study of 3779 patients found women were 20% less likely to undergo an exercise test or angiography due to suspected coronary obstruction. Despite proven coronary disease, women received less aggressive treatment and were twice as likely to die or suffer a heart attack compared to men.

Cardiac benefits of sport

Increased physical activity reduces coronary heart disease and cardiac mortality rates by 30-40% compared to inactive individuals. Exercise training also improves endothelial function, reducing atherosclerosis and plaque formation, and can even extend life expectancy in patients with stable coronary artery disease.

Arrhythmias and sport

The study found that adolescents and young adults involved in competitive sports had a two and a half times higher risk of sudden death. ECG screening identified vulnerable young people, reducing sports-related sudden death from hypertrophic cardiomyopathy.

Percutaneous aortic valve replacement

The Cribier-Edwards Percutaneous valve offers a less invasive solution for patients with fibro-calcific native aortic valves, reducing mortality rates associated with untreated disease. Recent developments include custom retrograde delivery systems and larger valve sizes, improving procedure success rates.

NORVIT

Researchers from Norway found that treating patients with high doses of B vitamins after a heart attack does not prevent recurrent heart disease or stroke. In fact, high doses of B vitamins may increase the risk of cardiovascular disease, particularly among those with impaired renal function.

ESC Congress 2005: ISSUE II

A new study demonstrates that improved patient selection methods lead to significantly better therapy outcomes for patients with suspected neurally-mediated syncope. The study used implantable loop recorders and found a lower recurrence rate in patients who received pacemaker therapy.

US specialists call for heart patients to be screened for psychological distress

Research by Dr Amy Ferketich and Dr Philip Binkley found that men and women with heart disease in the US experience high levels of psychological distress, with only a third seeking mental health support. The study analyzed data from over 17,000 individuals with different forms of heart disease, highlighting the need for clinicians to c...

SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·DateJun 8, 2005