New research reveals distinct differences in early human embryo development among overweight and obese women compared to those of a healthy weight. These differences may have long-term health implications for their children.
A major new trial aims to provide clear guidance on whether home oxygen therapy should be offered routinely to patients with chronic heart failure. The study will measure factors such as patient quality of life, exercise ability, and breathlessness to determine the effectiveness of hot.
A new report shows that integrated heart failure services can reduce unwanted hospital deaths, allowing many patients to die at home. The study found that specialist nurses played a pivotal role in discussing end-of-life care with patients, enabling them to make plans and set their affairs in order.
Researchers at the University of Hull are developing a system to produce constant supplies of sterile water, eliminating the need for chemicals or electricity in remote communities. The device uses porphyrin molecules that react to sunlight to kill bacteria and parasites, making the water safe for healing wounds.
Researchers from the University of Hull have identified a family of proteins associated with chemotherapy resistance in breast cancer patients. The 14-3-3 protein family was found to be twice as prevalent in resistant patients, suggesting its potential use as a predictive test for clinical decision-making.
Scientists at the University of Hull found that highly suggestible individuals can see colours in monochrome patterns and experience changes in brain activity under hypnosis. The study suggests that these abilities exist independently of hypnosis and may be useful for medical interventions, such as pain control.
A three-year project led by University of Bangor aims to assess how climate change affects the movement of muddy sediments in rivers, estuaries, and seas. The study focuses on the interaction between cohesive muds and sandy sediments, which plays a crucial role in understanding coastal erosion and deposition.
Researchers have developed a new technique that can identify protein structures in just hours, revolutionizing the pharmaceutical industry. The enhanced NMR spectroscopy method using dynamic nuclear polarisation (DNP) enables significant structural data to be gained from small biological samples.
A University of Hull study found that weeds are vital to the existence of many farmland species, providing food for over 330 species of insects, birds, and animals. The research also showed that increasing farm management intensity can lead to a decline in seed biomass and energy, affecting farmland biodiversity.
A new class of drugs called cardiac myosin activators targets the motor proteins in heart failure patients, prolonging contraction duration and improving blood pumped per stroke. Omecamtiv mercabil shows promise as a safe and effective treatment option with minimal increased energy expenditure.
Research found that embryos exposed to high levels of saturated fatty acids have fewer cells, altered gene expression, and impaired metabolic activity. This study suggests a link between maternal obesity and diabetes and reduced fertility, highlighting the importance of pre-pregnancy health for successful conception.
The new nanoparticles can carry hundreds of light-sensitive molecules, creating more reactive oxygen species from the same amount of light. This design allows the nanoparticles to penetrate easily into tumors and deliver targeted damage to cancer cells.
Researchers have developed a new technique using light-sensitive molecules and antibodies to target tumour blood vessels, starving cancer cells of oxygen and nutrients. The treatment was shown to completely eradicate some models of skin cancer in clinical trials.
Scientists at the University of Hull have identified a cellular mechanism controlling tissue factor inclusion in endothelial microparticles, which may help treat cardiovascular disease and cancer. The on-off switch, involving tandem amino acids, regulates phosphate molecule addition to control tissue factor release.