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Weizmann Institute of Science


Birth of an enzyme

Researchers designed an enzyme for a specific reaction using computational design, but the synthetic enzyme was less efficient than naturally occurring ones. However, by allowing the enzyme to undergo 'evolution in a test tube,' they were able to improve its efficiency 200-fold and increase reaction rates by a million-fold.

Repeating genes

Scientists at the Weizmann Institute have proposed a mechanism that explains the precision of trinucleotide repeat diseases like Huntington's. They suggest that the genes carrying the disease code accumulate more DNA repeats over time until a critical threshold is crossed.

SourceWeizmann Institute of Science·JournalPLOS Computational Biology·DateNov 22, 2007

A gene for metastasis

Researchers discover that the L1-CAM gene is highly expressed in colorectal cancer cells that have spread to the liver, while normal colon tissue lacks this gene. This finding highlights the importance of L1-CAM in metastasis and opens new avenues for cancer research.

SourceWeizmann Institute of Science·JournalCancer Research·DateAug 28, 2007

Switching goals

Researchers found that evolving to complex goals accelerates speedup in simulations, suggesting a possible shortcut to optimization. The study's findings have practical implications for engineering fields and computer science.

SourceWeizmann Institute of Science·JournalProceedings of the National Academy of Sciences·DateAug 28, 2007

Memory machine

Scientists found that long-term memories require a miniature molecular machine to maintain, which must be constantly active. Jamming this 'machine' can briefly erase memories, suggesting potential future treatments for memory problems.

SourceWeizmann Institute of Science·JournalScience·DateAug 16, 2007

Live broadcasts

Researchers have developed a genetically modified mouse model using the ferritin reporter gene, enabling live cell imaging via magnetic resonance imaging (MRI) without additional substances. This breakthrough overcomes limitations in detecting signal changes in tissues, such as fetal development and the central nervous system.

SourceWeizmann Institute of Science·JournalNature Medicine·DateJul 26, 2007

Opposites interfere

Researchers at Weizmann Institute of Science observe oscillating interference pattern between two identical quantum particles, proving quantum theory's predictions. The particles' actions are inextricably tied due to entanglement, even when separated by distance.

The inside dope

Scientists at the Weizmann Institute of Science have successfully implemented doping in molecular electronics, enabling the control of electronic properties in organic molecules. This breakthrough could lead to the creation of environmentally friendly and versatile electronic components.

SourceWeizmann Institute of Science·JournalJournal of the American Chemical Society·DateJul 26, 2007