Researchers at the Weizmann Institute have developed a new form of adoptive cell transfer that overcomes limitations of current therapies. This approach uses a donor pool of immune T cells prepared in advance, which are outfitted with receptors to specifically target and destroy tumors.
Researchers developed a model that mimics three predator-prey modes to understand cloud-rain interactions, finding that aerosols affect cloud formation and precipitation. The study provides new insights into the complex relationships between clouds, rain, and aerosols, shedding light on climate patterns and human-induced changes.
Scientists at the Weizmann Institute of Science have identified a biological sign of autism in very young toddlers by scanning their brain activity while sleeping. The study found that autistic brains exhibited weaker synchronization between brain areas tied to language and communication compared to non-autistic children.
A study at the Weizmann Institute found that false memories are formed when our brains rely on false information from others, which is reinforced by social pressure. The researchers discovered a unique pattern of brain activity associated with this process, highlighting a surprising connection between social and memory processing.
Researchers discovered that cancerous cells quickly divide after receiving a growth factor signal because their p53 gene is defective. Healthy cells, on the other hand, wait eight continuous hours before dividing to ensure they receive necessary signals.
Researchers discovered that caspase-8, an enzyme previously thought to only prevent inflammation through apoptosis, can also control inflammation by destroying a protein called RIP1. This new mechanism could lead to the development of effective therapies for inflammatory disorders like rheumatoid arthritis and inflammatory bowel disease.
Researchers at the Weizmann Institute developed a quantum version of a locked-in amplifier using a single atomic-ion detector, achieving spatial resolution of just a few nanometers. This technique improves the sensitivity of quantum sensors by around 100 times.
Weizmann Institute scientists discover that adverse experiences can impair perception, making it harder to distinguish between similar stimuli. This finding may contribute to the development of anxiety disorders like post-traumatic stress syndrome.
Researchers found that PTPe inhibits certain molecules, dampening the leptin signal and reducing appetite and increasing physical activity. The discovery suggests that inhibiting PTPe might help reestablish the leptin response in obese humans with leptin insensitivity.
A team of researchers found that half of all learned insights are consolidated in our memories, and the amygdala plays a crucial role in this process. The study used camouflage images to induce sudden insight, and participants' ability to identify the images was predicted by amygdala activity.
Research by Prof. Ron Naaman and colleagues reveals that biological molecules, such as DNA, can discern between quantum states of spin, a phenomenon previously thought irrelevant to their function due to their size and temperature. This chiral property enables them to selectively interact with electrons carrying specific spins.
Researchers found that half of learned insights are consolidated in memories within a week, while others fade over time. The amygdala, associated with emotion, is activated during insight moments and predicts ability to recall degraded images.
The study found that three urocortin proteins play a central role in regulating stress responses and shutting down the stress response. Genetically engineered mice lacking these proteins showed impaired recovery from stress, highlighting their importance in returning to normal behavior.
Two new studies provide definitive evidence that administering a naturally-occurring enzyme called oxolacetate can reduce glutamate levels and improve outcomes in stroke patients. High glutamate levels correlate with poor outcomes, while high oxolacetate levels are associated with better recovery.
Researchers used accelerated evolution to engineer enzymes that can efficiently break down nerve agents, providing protection against nerve gas attacks. The developed enzymes show near-complete protection against certain types of nerve agents.
Researchers at the Weizmann Institute discovered that antioxidants can cause a decrease in ovulation levels in female mice, potentially disrupting fertility. The study suggests that reactive oxygen species play a crucial role in the ovulation process and may be affected by antioxidant supplementation.
Researchers found that sniffing women's emotional tears reduces men's sexual arousal and decreases testosterone levels, but has no impact on emotional responses or empathy. The study uses fMRI scans to reveal brain activity changes in response to tear exposure.
The full genome of the wild strawberry plant has been sequenced, revealing insights into its unique flavor and aroma compounds. The research provides a new model for studying agricultural crops and fruit trees, such as apples, peaches, and almonds.
A new device developed at the Weizmann Institute uses sniffing technology to enable communication and wheelchair steering for severely disabled individuals. The device was tested on healthy volunteers and quadriplegics, showing promising results in mastering the skill, which can also be used as a 'third hand' for surgeons and pilots.
Researchers identify third type of supernova with unique chemical composition, suggesting a pair of white dwarves are involved. This discovery may explain the prevalence of certain elements in the universe and account for observed concentrations of particles called positrons.
Researchers have discovered a link between stress, anxiety, and metabolic changes that can lead to type 2 diabetes. The study found that increasing the activity of a single gene in the brain causes mice to exhibit anxious behavior and develop symptoms associated with type 2 diabetes.
Weizmann scientists trained an electronic system to predict the pleasantness of novel odors, similar to human perception. The eNose achieved high accuracy rates, regardless of cultural background, suggesting a fundamental biological property in odorant pleasantness.
A recent study on the zebra finch genome suggests that smell may be involved in bird communication, contrary to earlier assumptions. The research found that around 200 genes can potentially produce functional smell receptors, supporting the idea that some birds rely on their sense of smell.
Researchers at the Weizmann Institute of Science found that bats aim their sound beams off-center when locating objects, making this strategy more efficient than aiming directly at the center. This approach allows bats to better track movement across the beam.
Researchers found that semi-arid forests can counteract global warming by absorbing and retaining heat, but this effect may be cancelled out by other processes. The 'air cooling' system in these forests efficiently reduces infrared radiation, leading to a net warming effect.
Researchers found that tendons play an active role in initiating bone ridge patterning and regulating skeletal growth. The discovery sheds light on a key mechanism underlying the assembly of the musculoskeletal system.
Scientists identified rapid bursts of neural activity in high-order visual centers when patients correctly recognized target images, suggesting a 'threshold' for conscious perceptual awareness. The study found that brain processing time is crucial for ignition, with mask presentation too soon 'killing' visual input signals.
Researchers discovered a single gene, SIMYB12, that regulates the production of yellow pigments and other substances in tomatoes. The mutation affects flavonoid levels, leading to less lycopene and altered cuticle composition.
Scientists at Weizmann Institute of Science have developed a new method for transplanting bone marrow-based stem cells from mismatched donors, restoring the immune system faster and improving cure rates for leukemia patients. The procedure involves infusing regulatory T cells into cancer patients before receiving donor stem cells, lead...
Researchers discover supernova that fits predictions for a star hundreds of times the sun's mass, revealing new insights into star formation and heavy metal creation. The study also suggests hyper-giant stars may exist beyond 150 suns, challenging our understanding of celestial physics.
Researchers found that the first association between a smell and an experience leaves a lasting impression in the brain. After one week, they could predict which associations would be remembered based on brain activity alone.
Researchers at Weizmann Institute discovered a new protein partnership between TrkA and CCM2 that leads to pediatric tumor regression. This finding may lead to the development of drugs that induce tumor regression. The study found that TrkA and CCM2 are always expressed together in tumors with high regression rates.
Researchers at Weizmann Institute of Science have developed a program for biomolecular computers that enables logical thinking. The device can answer intricate queries involving multiple rules and facts, performing millions of calculations in parallel.
Researchers found that certain microorganisms like E. coli and wine yeast have genetic networks that allow them to 'foresee' upcoming events and respond accordingly. This adaptation increases their chances of survival, similar to how Ivan Pavlov's dogs learned to salivate in response to a stimulus.
Researchers discovered that the teeth contain crystals of magnesium calcite, which are smaller, harder and denser than those of pure calcite. The unique arrangement of these crystals in two different arrays allows them to be self-sharpening as they wear down.
A recent study by Prof. Zvi Livneh reveals the two-step mechanism of stopgap DNA repair, a major source of mutations in cells. Understanding this process can lead to enhanced treatment options for individuals with deficient natural DNA repair, as well as improved chemotherapy effectiveness against cancer.
Weizmann Institute scientists have discovered that white blood cells use a unique method of movement, similar to millipedes, to crawl along the lining of blood vessels. The cells create tiny 'legs' that attach and detach in sequence, allowing them to move rapidly while keeping a good grip on the vessel's sides.
Researchers have developed a new mechanism for water splitting, which generates oxygen gas from water molecules. The process is divided into three stages, utilizing light and heat to produce clean fuel.
Scientists have directly observed a gigantic star blowing up, supporting the idea that massive stars end as black holes. The explosion revealed most of the star's mass collapsed into a dense core, creating an invisible black hole.
Researchers have discovered that brain activity remains active even when the eyes are closed, with slow fluctuations dominating during rest. The study's findings could lead to advanced diagnostic techniques and a better understanding of brain function.
Researchers found that extra copies of the LIS1 gene can cause problems, including smaller brains and developmental abnormalities. Studies in mice and human patients revealed a link between the duplicated gene and brain diseases such as schizophrenia and autism.
Researchers developed a mathematical model to evaluate the efficiency of bacterial protein production, finding that optimal efficiency requires seven genes for ribosome production. The model accurately predicted how E. coli adapts to disruptions in production workflow.
Researchers developed an imaging method to analyze thousands of living cells and reveal how a chemotherapy drug affects each one. They identified two proteins, DDX5 and RFC1, that play a role in cancer cell survival and boosted the effectiveness of current drugs.
Researchers designed nerve networks with varying widths to mimic brain connections, creating logic gates and biological clocks. They discovered a threshold thickness for axon development, allowing for the growth of around 100 axons, essential for signal transmission.
Researchers reconstruct cancer cell family tree using novel method, tracing developmental history and growth pattern. The technique enables estimation of cell depth, a key factor in understanding cancer behavior.
Weizmann Institute scientists have discovered a mechanism that enables an injured embryo to regenerate itself while maintaining the relative proportions of its organs. The research reveals that inhibitor molecules shuttle morphogen between sides of the embryo, keeping organs proportional regardless of size.
Researchers deliver genetically engineered T-reg cells to the intestine to suppress inflammation and autoimmunity. The 'bystander' effect enables these cells to target diseased tissue, suppressing inflammatory cells and promoting healing.
Researchers at the Weizmann Institute have created 'quasiparticles' with a fraction of an electron's charge, which could enable powerful yet stable quantum computers. The discovery was made using an extremely precise setup and unique material properties.
Researchers found that frequent temperature measurements can alter the behavior of quantum systems, allowing them to heat up when hotter than the bath and cool down when colder. This effect is due to decoupling from the heat bath during measurement, introducing energy into the system and altering its temperature.
Researchers mapped and digitized smells, discovering a multidimensional map of odors that reveals the distance between molecules. The study found that the brain recognizes this map, similar to musical scales, supporting the theory that there are universal laws governing smell perception.