Scientists identified the mix of elements thrown off by the star before its explosion, which helped paint a picture of how heavy elements in the universe are formed. The findings revealed a nitrogen-rich wind similar to those of Wolf-Rayet stars, providing a window into the workings of the cosmos.
Researchers at the Weizmann Institute have discovered a new type of cellular vesicle that actively seeks out and destroys paternal mitochondria upon fertilization. This finding may help explain why only a quarter of IVF pregnancies carry to term, and could lead to a better understanding of mitochondrial turnover and male fertility.
A Weizmann Institute of Science study reveals that daily fluctuations in triglycerides in the liver are driven by internal 'body clocks' and timing of meals. Researchers found that restricting nighttime feeding led to a 50% decrease in liver TAG levels, suggesting that meal times can affect lipid accumulation.
A 300,000-year-old hearth discovered in the Qesem Cave provides conclusive evidence of repeated fire building over time, hinting at advanced social structure and intellectual capacity. The find suggests that early humans had a sophisticated understanding of space organization and social order.
Researchers at the Weizmann Institute of Science have identified a key player in triggering brain inflammation and nerve cell death in severe forms of Gaucher disease. This discovery may lead to new treatments, including those that can cross the blood-brain barrier to target neurological symptoms.
Researchers at the Weizmann Institute of Science have developed a system to investigate microglia functions, revealing their role in shaping neuronal networks and contributing to neurodegenerative diseases. The study uses a genetic switch to target microglia cells, shedding new light on their mechanisms of action.
A new method combines high-throughput DNA sequencing and computer analysis to produce reliable maps describing contacts between genes along individual chromosomes. The results suggest that the arrangement of genes on chromosomes is modular and based on their functions, with active genes exposed at chromosome boundaries.
Researchers have developed a nano-SQUID-on-tip that measures magnetic fields at distances as small as a few nanometers from the sample, breaking the record for sensitivity and resolution. This tiny device may also enable measuring the magnetic field from the spin of a single electron, a major breakthrough in magnetic imaging.
Researchers at the Weizmann Institute of Science have successfully created induced pluripotent stem cells (iPS cells) that can be kept in a pristine state, paving the way for growing transplant organs to order. The breakthrough enables the production of 'humanized' mouse models containing human-derived tissues.
A study at the Weizmann Institute suggests that in a quarter of all leukemias, cancer cells use a balance between a mutated gene and its normal counterpart to keep going. The healthy RUNX1 gene plays a crucial role in blood cell development and maintenance.
Researchers find removing MBD3 protein increases efficiency of stem cell reprogramming from 1% to 100%, allowing for faster production of cells for medical use. This breakthrough provides a deeper understanding of embryonic development and could advance treatment of various diseases.
Scientists have mapped out the biochemical pathway responsible for manufacturing glycoalkaloids in plants, which are toxic substances found in potatoes and other edible plants. The research could facilitate breeding of toxin-free crops and development of new crop varieties.
Researchers found that maintaining a safe distance between transcription enzymes is crucial for efficient production of microRNAs. By launching enzymes at lower rates, they can avoid 'traffic jams' and create more molecules.
Scientists have successfully created self-integrating nanowires whose position, length and direction can be fully controlled. This breakthrough enables the production of electronic circuits with hundreds of transistors simultaneously, opening doors to various technological applications including LED devices, lasers, and solar cells.
Archaeologists at the Weizmann Institute of Science have discovered the oldest known use of flowers in grave lining, dating back 11,700 to 13,700 years. The graves were found to contain Judean sage, mint, and figwort plants, which suggest that ancient humans had a positive association with flowers.
Researchers at the Weizmann Institute developed a system to track mouse behavior, revealing signs of leadership and a class system in groups of normal mice. In contrast, experiments with autistic-like mice showed little emergence of dominant leaders or social structures.
A team of scientists has determined that the atmospheric layer on Uranus and Neptune extends only about 1000 km in depth, a significant finding that challenges current understanding of these planets' weather systems. This discovery was made possible by analyzing gravitational field data using novel methods.
Scientists track Egyptian fruit bat flights using miniature wireless devices and find that place cells respond to spherical volumes of space, suggesting uniform perception of all three dimensions. The study provides new insights into navigation, spatial memory, and spatial perception.
A recent Weizmann Institute study has discovered that caspase 8 signaling enzymes, which were previously thought to only induce programmed cell death, can also activate an entirely different process in certain cells - causing inflammation more directly. This finding highlights the need for further research into the signals transmitted ...
Weizmann Institute researchers found that measuring a single atom's spin can collapse its superposition into one state. By adjusting the polarization of the emitted photon, they demonstrate that observers can influence the spin collapse, suggesting an 'action-at-a-distance' effect.
Researchers at the Weizmann Institute of Science created a two-dimensional cell-like system on a glass chip, enabling precise observation of gene expression and protein behavior. The system allows for the simultaneous production and trapping of multiple proteins, revealing a spectrum of protein activities.
Scientists have observed a rare pre-explosion outburst occurring just one month before a massive star underwent a supernova explosion. The findings validate a particular model predicting this type of event and provide insight into the processes taking place in the cores of such massive stars.
Researchers propose using two EGFR-blocking antibodies to treat triple-negative breast cancer, which lacks common receptors for hormone-based treatments. In a study, combining two antibodies proved effective in preventing tumor growth and spread in mice.
Scientists have created a blended scent, known as 'Laurax,' which spans the entire range of human olfaction and is perceived as neutral. This breakthrough challenges conventional wisdom on how our sense of smell works.
A team of researchers at the Weizmann Institute has discovered how immune cells produce a wide range of receptors to fight different diseases. By analyzing the genetic sequences of lymphocyte receptors in mice, they found that the flexibility and length of DNA segments play a crucial role in determining the likelihood of two distant se...
Researchers discovered that bacteria in arsenic-rich environments developed a protein, PBP, with extreme selectivity for phosphate over arsenate. The unique bond between the protein and arsenate molecule led to repulsion and prevented its entry into the cell.
A recent study has revealed the existence of a rare sub-group of activated immune cells that act as bodyguards to protect stem cells from premature differentiation. These macrophage cells secrete prostaglandins, which delay differentiation and preserve the youthful state of the stem cells.
Researchers confirm experimentally that quantum effects allow chemical reactions to proceed rapidly, even at low energies. By merging beams of particles, they achieved a collision temperature of just 0.01 K and observed dramatic changes in reaction rates, revealing the power of quantum phenomena in cold chemistry.
A new model developed by Weizmann Institute mathematicians and physicians proposes a more individualized approach to chemotherapy by considering not only the quantity but also the quality of blood cells. This could lead to better precautions for high-risk patients and spare unnecessary preventive treatments for those at low risk.
A team of researchers developed an automated system to map protein-DNA interactions, uncovering a hierarchical structure for the regulatory code. They found that regulatory factors can be classified into three levels, with each tier governing cell type, sub-identity and specialized gene expression.
A Weizmann Institute study found that people can learn new information while sleeping and retain it unconsciously, modifying their waking behavior. The research used a type of conditioning involving tones and odors presented during sleep, leading to responses similar to those experienced when awake.
Researchers discovered that importin beta1, a crucial protein for nerve repair, is produced locally in the axons of peripheral nerve cells. This finding has significant implications for treating nerve damage and may lead to better treatments and faster repair.
Researchers found that pyrite, also known as fools' gold, plays a significant role in regulating atmospheric oxygen levels. The formation and burial of pyrite has been more important than previously thought, accounting for over 80% of sulfur removed from the ocean.
A new Weizmann Institute-led study identifies a potential molecular mechanism behind the link between cancer and faulty stem cell differentiation. The researchers discovered that the tagging of DNA pieces with ubiquitin is crucial for proper stem cell differentiation, and disruptions in this process can lead to cancer.
Researchers discovered that the Microprocessor complex adjusts its production levels based on available precursor miRNA, reducing the risk of chopping off-target RNAs. This finding has implications for efficiently producing small RNA therapies for diseases.
The new study proposes a way to effectively introduce carefully planned DNA segments into genomes of living cells and test the effects. The technology enables simultaneous introduction of tens of thousands of DNA regions into tens of thousands of living cells, allowing for precise measurement of results within a single experiment.
A study by Weizmann Institute scientists reveals that leukemia recurrence is often caused by 'cancer stem cells' that divide slowly, evading chemotherapy drugs. These cells can give rise to new rapidly-dividing cancer cells, making them a key target for new treatment approaches.
Researchers found that the Moon's synchronous rotation with Earth is due to its geophysical properties, not a result of chance. The near side of the Moon resembles the Man in the Moon due to volcanic material, while the far side has higher mountainous regions.
Weizmann Institute scientists have disproved a claim about the origin of eggs in female mammals and created a new method for reconstructing lineage trees for cells. The study found that ova cannot be descended from bone-marrow stem cells, but older mice eggs undergo more cell divisions than younger ones.
A new on-off switch for hormone production has been discovered in the brain by Dr. Gil Levkowitz's team, which regulates corticotropin-releasing hormone (CRH) release. The switch involves a protein called Otp that activates CRH genes and regulates receptor variants, potentially contributing to stress-related disorders.
A new study reveals that cells employ a dual-pump mechanism to maintain optimal nutrient levels, allowing for efficient preparation for starvation and rapid recovery afterwards. This regulatory system enables the cell to deal with fluctuations in nutrient supply, offering crucial survival advantages.
Scientists have developed a new approach to treating autoimmune diseases by creating artificial antibodies that target the MMP9 enzyme. These 'metallobodies' mimic natural inhibitors and selectively block two members of the MMP family, preventing symptoms in mice with inflammatory conditions.
The study of the closest supernova in 25 years has shed new light on its formation. The team found that the exploding star was a white dwarf, and while they couldn't rule out a white dwarf merger, their results suggest a medium-sized star supplied the white dwarf with extra material to trigger the explosion.
New research at the Weizmann Institute shows how blood vessel cells 'hide' signals from immune cells, only allowing those with special training to cross. This selective barrier prevents certain immune cells from reaching tumors near blood vessels.
Researchers have discovered that a mutation in the CLN3 gene disrupts protein trafficking, leading to lysosome overflow and neuronal death in Batten disease. The findings may form the basis for a new therapy by targeting the kinase function of CLN3.
Researchers discovered a crucial brain area, neuro-hypophysis, where biochemical commands are passed from the brain to the bloodstream. They found that oxytocin, known as the 'hormone of love,' plays a key role in the development of this structure, governing blood vessel formation during embryonic stages.
Researchers found that smell receptors are grouped into distinct sites on the nasal membrane, each engaging most strongly with a particular type of scent. The intensity of reactions is linked to the odor's place on a pleasantness scale, suggesting an organizing principle for our sense of smell.
Scientists Profs. Naama Barkai and Ben-Zion Shilo have developed a theoretical model explaining how scaling works in developing fruit fly wings, where the vein structure stays proportioned. Their findings suggest that this mechanism can be applied to various examples of development, including human embryonic development.
Scientists have discovered that about a quarter of Type Ia supernovae are born from medium-sized stars similar to our Sun. This finding challenges the long-held assumption that all Type Ia supernovae have the same luminosity, which is crucial for measuring cosmic distances.
Scientists at the Weizmann Institute of Science have developed a method to grow semiconductor nanowires on a surface, producing relatively long, orderly, aligned structures. This breakthrough enables the production of enhanced electronic and optical properties suitable for various applications.