Researchers discovered Plasmodium falciparum uses nanovesicles to deliver misleading messages to the immune system, allowing it to multiply unhindered. The team identified a key molecular sensor called STING that plays a crucial role in this subversive strategy.
A team of scientists and archaeologists has discovered a 15,000-year-old Natufian site in Jordan that pushes back the timeline for permanent settlement in the region. The site's early dates suggest that hunter-gatherers were more versatile than previously thought and had multiple pathways to agriculture.
Researchers at Weizmann Institute of Science found that individuals on the autism spectrum exhibit distinct reactions to 'smells of fear' and 'calm sweat', including changes in anxiety levels. This suggests a possible underlying connection between smell, social cues, and early brain development in autism.
Research at Weizmann Institute of Science uncovers mechanisms driving storms toward the poles. Mid-latitude storms steer further poleward in a warmer climate due to vertical structure and circulation near the tops of these weather systems.
Researchers at the Weizmann Institute of Science have created a novel method for cooling ions using electrostatic fields, allowing them to reach temperatures near absolute zero. This breakthrough enables the study of large biological molecules and nanoparticles, with potential applications in medicine and materials science.
Researchers at Weizmann Institute of Science find that oxygen-starved killer T cells are more effective at destroying cancerous tumors and outperform regular T cells in a mouse model. The study suggests an easy improvement to existing immunotherapy protocols.
Scientists have identified a class of mammalian lncRNAs that evolved from ancestral genes, gaining regulatory powers and serving as master switches in various biological processes. These 'recycled' genes may hold the key to understanding human diseases and developing new treatments.
Researchers discover bacteria in pancreatic tumors that metabolize a common chemotherapy drug, rendering it ineffective. The study suggests that targeting these bacteria may offer a new approach to treating pancreatic cancer.
Researchers have discovered that self-assembling protein complexes can form long, stiff filaments through a single mutation. This phenomenon has implications for both biological research and nanoscience, as it may indicate that Lego-like assemblies are more common than previously thought.
Researchers developed a new theory to understand how cracks propagate, revealing a nonlinear relationship between forces and material response near the crack's edge. This discovery may lead to better understanding of material failures and development of new strategies for protecting the environment.
Researchers discovered that intestinal cells use a strategy to increase protein production within minutes of food entering the intestines, enabling fast and efficient processing. This approach has potential medical implications for diseases such as colitis, Crohn's disease, and bowel cancer.
A new study reveals that beets can produce a pigment with high antioxidant properties, boosting crop nutrition and resistance to disease. The researchers successfully engineered plants to produce this pigment, which also showed promise in controlling gray mold in crops.
Researchers have developed microscopic silk capsules that can protect sensitive molecules, such as natural silk proteins, antibodies, and other delicate molecules. These biodegradable capsules may enable the development of new treatments for neurodegenerative diseases by delivering drugs or vaccines intact to target organs.
Research at Weizmann Institute of Science finds dust storm microbiomes differ by region, with rising bacterial species during storms. The study identifies a 'signature' for each source of bacteria based on antibiotic resistance genes, revealing that local sources pose less threat than imported genes.
Researchers at the Weizmann Institute of Science used advanced radiocarbon dating methods to determine the age of a massive stone tower in Jerusalem. The new date, around 800-900 BCE, is nearly 1,000 years younger than the previously assigned date of 1700 BCE and moves the construction of the tower to the Iron Age.
Researchers at the Weizmann Institute of Science have developed a method to overcome the fundamental limit on particle density in atomic and molecular-beam experiments. By cooling skimmers to lower temperatures, they significantly reduced shockwaves and increased beam density, enabling more interesting chemical reactions.
A new study found that whole grain breads, once thought healthier, may not have a significant impact on blood sugar levels. The researchers discovered that an individual's unique microbiome plays a crucial role in how their body responds to different types of bread.
A study by Weizmann Institute researchers reveals that administering 'young matrix' molecules, including Agrin, to damaged mouse hearts can repair and restore heart muscle function. The findings suggest a new direction for research on restoring damaged hearts and may lead to the development of new treatments for heart disease.
Researchers at Weizmann Institute of Science establish a clear causal link between prenatal stress and the onset of eating disorders. Female mice exposed to maternal stress during pregnancy develop compulsive eating disorder when challenged with a Western diet, highlighting an epigenetic marker introduced prenatally.
A recent study identified around 6,500 human genes that are expressed differently in men and women, with some genes playing a crucial role in body hair growth, muscle building, and fat storage. The research suggests that natural selection puts less pressure on genes specific to one sex or the other.
White blood cells use their nuclei to exert force and insert themselves between endothelial cells, creating large holes in the blood vessel walls. This discovery sheds light on the movement of immune cells and may aid in cancer research.
Researchers at Weizmann Institute of Science directly observed crystallization process on molecular level, validating recent theories and showing that knowing how crystal grows can predict end structure. The study found that dense phases lead to lower energy barrier and more stable crystals.
Researchers developed a new method for programming proteins used in vaccines against infectious diseases, enabling stable production and lower costs. The approach has shown promising results in animal trials, provoking a protective immune response.
Researchers discovered a separate mechanism in the brain that deals only with chronic stress, involving a small group of nerve cells in the paraventricular nucleus. The CRFR1 system is thought to play a role in regulating cortisol levels and may be involved in depression, with patients having more of this receptor than average.
Researchers have developed a method to predict interactions among multiple drugs in combination, bypassing the need for astronomical measurements. The new mathematical model enables scientists to identify optimal blends for chemotherapy cocktails and potentially aid personalized medicine.
Researchers used gene expression analysis to map the functions of liver cells, revealing nine distinct types each specializing in its own tasks. This discovery may help clarify common liver disorders and provide insights into human health.
Weizmann Institute scientists have successfully erased fear memories in mice by disrupting the communication between two brain regions. The study, published in Nature Neuroscience, may one day lead to novel therapies for post-traumatic stress disorder (PTSD) and other anxiety disorders.
Researchers discovered that massive stars can exhibit instability for several months before a supernova explosion, creating a dense gas shell around themselves. This insight came from analyzing data collected by the Palomar Transient Factory telescope network.
Researchers suggest ancient ocean had green rusty mineral, green rust, which could have delivered substantial proportion of iron to early ocean sediments. Green rust forms under low oxygen conditions and can transform into iron oxides over time.
Researchers have identified ancient fava beans in Northern Israel, dating back 14,000 years, to understand the evolution of the crop and improve its biodiversity. The findings provide crucial clues about the time and place where wild faba plants grew naturally.
By controlling electron spin, scientists have almost fully suppressed hydrogen peroxide formation during water splitting, paving the way for efficient solar-based hydrogen production. This breakthrough could lead to more stable and efficient photoelectrochemical cells, increasing the feasibility of using solar energy to split water.
Researchers developed a model suggesting early oceans were acidic, with pH between 6.0 and 7.5, conducive to primitive life's existence. Higher CO2 levels controlled ocean acidity, influencing chemical weathering and ion fluxes.
Scientists have discovered that sea urchins extract calcium ions from seawater through a process where they drink in water and manipulate the ions within their cells. This method is more energy efficient than previously thought, but presents new challenges for understanding how these cells concentrate and expel ions.
A new database of plant metabolites and computer tool have been developed to identify healthful antioxidants in tomato skins. The researchers found that valuable substances produced by exotic plants may be derived from more common species, and these findings suggest a broader range of potential uses for plant metabolism.
Researchers have combined CRISPR gene editing with single-cell genomic profiling to understand nuanced cellular processes. The new technology enables precise manipulation of genes in individual cells, revealing previously unknown functions and advancing the field of genetic engineering.
Astronomers discovered a rare event where a star was destroyed by a massive black hole's gravitational tides, producing an unusually bright flash of light. The event occurred in a distant 'red' galaxy with older stars, defying typical supernova models.
Researchers at the Weizmann Institute of Science have identified a promising new combination therapy for triple negative breast cancer, which inhibits tumor growth and survival while preventing drug resistance. The therapy targets EGFR and PYK2 molecules, leading to a more potent therapeutic effect than inhibiting either molecule alone.
A new method of plant analysis has identified more than twenty metabolites in tomatoes that had never been reported before, including certain antioxidants in the skin. The Weizmann team's tools, WeizMass and MatchWeiz, can help study plant metabolism and identify useful biological activity
Sea urchins and microorganisms have been found to 'drink' seawater, extracting calcium ions through a network of bubbles within their cells. This method may be more energy-efficient than previous theories, but also presents challenges in manipulating ions in the sea water.
Researchers at Weizmann Institute of Science found that gut microbes contribute to recurrent 'yo-yo' obesity, with a 'memory' of previous obesity retained after dieting. They developed new treatments using fecal microbiome transplantation and flavonoids, which may help alleviate the obesity epidemic.
Researchers at the Weizmann Institute of Science identified a stress mechanism that regulates social behavior in mice, determining their willingness to form new relationships. The findings suggest that similar mechanisms may operate in humans, potentially informing treatments for social anxiety and other disorders.
Researchers created bowtie-shaped silver nanoparticles to study quantum phenomena, enabling strong coupling between photons and single quantum systems. The ability to control this coupling could lead to the development of more powerful computing and encryption devices.
A Weizmann Institute study found that viral infection during pregnancy disrupts the fetal immune system, leading to abnormal brain development and increased risk of neurodevelopmental disorders. The study suggests a possible explanation for how maternal infections raise the risk of autism and schizophrenia in offspring.
Weizmann Institute researchers successfully engineer E. coli bacteria to consume carbon dioxide and produce sugars, a breakthrough that could help address global food security and climate change. By adapting the bacteria's metabolism through evolution, scientists have created a new tool for studying and improving carbon fixation.
A recent study published in Cell Metabolism shows that neurons in the brain have a significant role in regulating metabolic responses to stressful situations. The CRFR1 receptor, typically associated with the sympathetic nervous system, is found to be expressed on cells involved in appetite regulation and energy expenditure.
Researchers used optogenetics to temporarily disconnect long-range axons, shedding light on the brain's internal communication. This study contributes to a better understanding of brain connectivity and its role in mental health diseases.
A new experimental platform is providing new insights into the complex problem of coral decline. The 'coral on a chip' system allows scientists to examine living coral polyps in the lab under controlled conditions.
Researchers found that circadian changes in mitochondria regulate energy levels and sugar use for energy production. The study suggests that timing of meals affects metabolic health.
Research reveals that people with anxiety have a hard time distinguishing between emotionally charged experiences and neutral stimuli, exhibiting a behavioral phenomenon known as over-generalization.
Researchers found that humans can recognize objects in partial- or low-resolution images, with a