Scientists have discovered the atomic structure of hemozoin crystals produced by malaria parasites, which could lead to improved antimalarial medications. This breakthrough is crucial for medical applications as existing structural knowledge was largely based on synthetic crystals.
Researchers found that Copaxone improves damaged mouse hearts by reducing inflammation and increasing blood supply to other organs. The drug also protects cardiac muscle cells from damage and promotes new blood vessel growth.
Scientists have discovered that immune cells migrate to the nasal conchae after vaccination or infection, secreting antibodies locally into the nasal cavity. This finding could lead to more effective nasal vaccinations and new treatments for autoimmune diseases.
A new study maps the human small intestine's activity areas, revealing effective nutrient absorption and protection against infection. The research also sheds light on slow-release fats and iron regulation in the body.
Researchers found a direct connection between massive star deaths and compact remnant formation, using observations of a nearby galaxy's SN2022jli supernova. The team detected periodic movements and energy signatures indicating a neutron star or black hole sucking up matter from its companion star.
A new study reveals that human tears contain chemicals that reduce aggression in others, similar to the tears of mice and blind mole rats. Sniffing women's emotional tears lowered brain activity related to aggression in men, reducing aggressive behavior in a two-person game.
Researchers create new method, called Zman-seq, to track and measure changes on single cells inside the body, revealing history of cells and advancing cancer therapy development. The breakthrough technique uses labeling cells with different time stamps and tracking them in healthy or pathological tissue.
Research reveals how diabetes disrupts lung immune cell function, leading to severe infections. Tight control of blood sugar levels or small molecule drugs may alleviate this susceptibility.
A new study finds that building solar farms in arid regions can effectively reduce greenhouse gas emissions, making it a more viable solution for addressing the climate crisis. By contrast, natural forests have a limited impact on carbon dioxide absorption due to their low albedo and high energy absorption rates.
Studies have shown that exposure to traumatic events at a young age significantly raises the risk of ill health, social problems and mental health issues later in life. However, research by Weizmann Institute scientists provides a reason for optimism.
Researchers have identified a new autoimmune disorder that disrupts tooth enamel development, specifically in children with celiac disease. The disorder is linked to the immune system's faulty education process, leading to autoantibody production that damages permanent teeth.
Researchers found that pyrite sulfur isotopes primarily reflect local conditions rather than the global sulfur cycle. The team developed a computer model to understand how sedimentary parameters affect the sulfur isotope composition of pyrite.
Researchers at the Weizmann Institute of Science have identified a novel immune mechanism that enables bacteria to survive on empty batteries, protecting them from viruses. This strategy has been conserved through billions of years of evolution and is also found in advanced species such as corals, bees, and fungi.
Researchers report the discovery of a hot Jupiter-like object orbiting a nearby star, offering insights into extreme planetary and stellar evolution. The binary system's brown dwarf component reveals temperature differences of up to 6,000 degrees between its dayside and nightside hemispheres.
Weizmann Institute researchers discovered a biomarker that may enable personalized drug treatment for lung cancer patients carrying the L858R mutation. This biomarker could lead to relapse-free treatment by predicting which patients will respond well to therapy according to their specific mutations.
Researchers from Weizmann Institute of Science discovered that a subcategory of brain cells responds to stress in a totally different manner in males and females. The findings could lead to better understanding of health conditions affected by chronic stress, such as anxiety and depression.
Researchers at Weizmann Institute of Science have discovered quantum vortices in strongly interacting photons. These vortices exhibit unique properties that can be used to study the behavior of photons and their interactions with matter.
A recent study reveals the combined weight of cattle, pigs, sheep, and other domesticated mammals surpasses that of wild terrestrial mammals, dwarfing their biomass by 30 times. Human impact on the environment is also strongly affecting the relatively limited remaining mammalian presence in nature.
Researchers at Weizmann Institute of Science develop the quantum twisting microscope (QTM) to explore quantum phenomena. The QTM allows for direct visualization of quantum electronic waves, enabling the creation of novel materials with unprecedented functionalities.
Researchers found a strong correlation between storm intensity, cloudiness, and solar energy reflection rate in each hemisphere. The study reveals that clouds are the linking factor between the brightness of Earth's surface and its appearance from space, solving the mystery of hemispheric symmetry.
Researchers calculated that terrestrial arthropod biomass is about 1 billion tons, with underground creatures responsible for soil fertilization and ecological balance. The study highlights the importance of arthropods in regulating vegetation and human health, emphasizing the need for monitoring their decline.
Researchers developed an algorithm that uses physics-based protein design calculations and machine learning to generate thousands of active enzymes, achieving a tenfold increase in success rate over traditional methods. The new method, CADENZ, has the potential to transform industries by providing green alternatives for processes such ...
Researchers developed a multiparameter approach for diagnosing cancer using a small blood sample, finding distinct patterns of epigenetic marking and protein segments between healthy individuals and cancer patients. The technology has shown high precision, with 92% accuracy, and could lead to a non-invasive and cost-effective blood test.
A controlled trial found that non-nutritive sweeteners alter human gut microbiomes and glucose tolerance in a personalized manner. The effects of the sweeteners on the microbiome were closely correlated with alterations in glucose tolerance.
Researchers have grown synthetic mouse embryo models from stem cells without fertilized eggs, opening new avenues for studying organ development and potentially producing transplantable tissues. The method shows promise in overcoming technical and ethical issues associated with natural embryo use.
Scientists have identified specific bacterial strains contributing to inflammatory bowel disease and developed a cocktail of specialized viruses to target them. The approach harnesses the precision of phages to selectively eliminate harmful gut bacteria, showing promise for treating Crohn's and ulcerative colitis.
Researchers found that type-3 innate lymphoid cells express the autoimmune regulator gene, which instructs T cells to fight Candida. Without this support, Candida-specific T17 cells cannot be generated, leading to ineffective elimination of fungal infections.
Researchers detected nonvisual traces of fire in ancient stone tools and fossil remains from Evron Quarry site, pushing the timeline of controlled fire use back to 800,000 years. The discovery suggests that early humans were experimentalists and could have played a crucial role in human evolution.
A study published in Science Advances suggests that people tend to form friendships with individuals who have a similar body odor. Researchers used an electronic nose to compare the chemical signatures of body odor samples from click friends and random pairs, finding significant similarities between the two groups.
A recent study published in Neuron sheds new light on ketamine's action on potassium channels in neurons, potentially leading to improved treatments for depression. The research found that ketamine enhances the Kcnq2 potassium channel in a specific subtype of glutamate-sensitive neurons.
A new study reveals climate change is causing winter storms to intensify faster than predicted, with implications for societies in the Southern Hemisphere. The research suggests that human activity may have a greater impact on this region than previously estimated, requiring rapid intervention to halt climate damage.
Researchers discovered that blood vessels forming from lymphatic vessels were found to be suited for specific functions. In transgenic zebrafish, they found that fins develop with lymphatic-derived blood vessels, which are perfectly suited for fin development.
A new study reveals that a subset of fibroblasts, known as Scleroderma-Associated Fibroblasts, are crucial to the development of scleroderma. The researchers found these cells in nearly 100 scleroderma patients and identified biological markers correlated with specific kinds of organ damage.
Researchers at Weizmann Institute of Science discover a new neuroprotective pathway linked to mutations in the IL18RAP gene, located in noncoding DNA. These protective mutations reduce inflammation and slow disease progression in ALS patients by nearly fivefold.
A study of over 12,000 respondents found that women, young adults, and the unemployed experienced increased mental distress due to COVID-19. Despite severe illness risks for certain groups, mental distress levels did not surpass past measurements.
A new study on bats reveals that their brain's GPS system represents three-dimensional space in a unique way, with grid cells packed like spheres rather than circles. The researchers found that this arrangement allows for local order but lacks global symmetry.
Researchers at the Weizmann Institute of Science used fruit bats to study navigation in an experimental setup that emulates their natural environment. They found that a single neuron can represent multiple place fields and that the size of each field changes according to location, resolving the discrepancy between traditional models.
A recent study has discovered a subtype of immune cells called dendritic cells, which become activated in the liver and promote the progression of non-alcoholic steato-hepatitis (NASH). Manipulating these cells may lead to new treatments for NASH, a condition that can lead to life-threatening cirrhosis and liver cancer.
Researchers found that beta-sitosterol reduced anxiety in mice by altering gene expression and neural pathways. The supplement showed synergistic effects when combined with an antidepressant, potentially reducing side effects. Further clinical testing is needed to confirm its effectiveness in humans.
Scientists have developed a new optogenetic tool using a mosquito-derived light-sensitive protein to investigate brain communication pathways. The researchers found that the protein enables precise control over specific neurons, allowing them to decipher neurotransmitter messages.
SARS-CoV-2 employs a three-pronged strategy to outsmart the immune system, including reducing gene translation, degrading messenger RNAs, and preventing mRNA export. This 'host shutoff' tactic delays and muddles the immune response, resulting in severe symptoms of COVID-19.
Scientists have discovered how a unique molecular switch in the brain causes feelings of fullness and may help develop improved anti-obesity drugs. The melanocortin receptor 4 is activated by setmelanotide, which binds to its binding pocket and enhances binding with calcium ions.
Scientists at Weizmann Institute of Science and MIT measure electronic entropy in twisted bilayer graphene, revealing giant magnetic entropy. The discovery provides an electronic analogue to the Pomeranchuk effect, where a material can exhibit unusual phase transitions.
Researchers have discovered that bacteria residing within tumor cells can be harnessed to provoke an immune reaction against the tumor. The findings suggest that bacterial peptides presented on tumor cells can serve as potential targets for immunotherapy, enabling immune T cells to recognize and attack cancer cells more precisely.
A study found that Australian fires created a spreading stratospheric haze, peaking in January to March and persisting through July. The particles were transported by mid-latitude cyclone belts and weather patterns, eventually settling around the entire hemisphere.
Mouse embryos can now be grown outside the womb for up to six days, allowing researchers to observe early stages of development in unprecedented detail. The method, developed by Weizmann Institute of Science researchers, enables detailed study of embryonic development and potential insights into birth defects.
Researchers found evidence of oxygen-using enzymes in ancient bacteria and archaea, dating back 3 billion years before the Great Oxygenation Event. This suggests that life forms already utilized oxygen long before the main event, which allowed for the evolution of humans and other oxygen-breathing organisms.
Scientists at the Weizmann Institute of Science mapped the entire stress axis in detail, identifying 21,723 cells along the route. They found significant alterations in gene expression and cell changes, particularly in the adrenal glands, which play a crucial role in the stress response.
A study by Weizmann Institute of Science researchers found that spontaneous brain activity in the visual centers can trigger vivid visual hallucinations in blind individuals with Charles Bonnet syndrome. The findings suggest a shared neural system for vision, imagination, and hallucination.
A study at the Weizmann Institute of Science reveals microplastics are swept up into the atmosphere and carried on the wind to remote parts of the ocean. The findings suggest these minuscule fragments can harm marine environment and affect human health through the food chain.