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New pathways of Alzheimer's disease identified

A new study has identified two main pathways involved in Alzheimer's disease, with one acting through amyloid and tau proteins and the other based on immune system reactions. The research also found that certain genes have opposite effects in men and women, suggesting a need for further investigation.

SourceUniversity of Lübeck·JournalGenome Medicine·TypeObservational study·DateOct 6, 2023

Oncotarget | Novel prognostic index to predict survival outcomes in gastric cancer patients

Researchers have developed a novel prognostic index to predict survival outcomes in gastric cancer patients. The inflammation-combined prognostic index (ICPI) combines three biomarkers - lymphocyte-to-monocyte ratio, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio - to provide a personalized prognosis for each patient.

SourceImpact Journals LLC·JournalOncotarget·TypeExperimental study·DateFeb 14, 2023

Dual-energy CT iodine concentration differentiates lung cancer from pulmonary metastases

Ringlike peripheral high iodine concentration maps from dual-energy CT can help guide management in patients with known lung cancer and an indeterminate solitary nodule. This finding showed excellent interobserver agreement, high specificity, and independently predicted pulmonary metastasis.

SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeObservational study·DateJan 11, 2023

Researchers propose a more effective method to predict floods

A team of researchers from Xi'an Jiaotong-Liverpool University and other institutions has identified a flexible and user-friendly model for predicting flood frequency in a changing environment. The fractional polynomial-based regression method is more effective than existing models, which often fail to account for factors like climate ...

SourceXi'an Jiaotong-Liverpool University·JournalJournal of Hydrology·TypeComputational simulation/modeling·DateJan 9, 2023

New study in Journal of Pharmaceutical Analysis reveals influence of host plant on medicinal qualities of mistletoe

A study published in Journal of Pharmaceutical Analysis found that the quality of mistletoe, a traditional Chinese medicine, is affected by its host plant. The researchers used metabolomics to investigate the influence of host plants and environmental factors on mistletoe's medicinal qualities. The results show that both host plants an...

SourceCactus Communications·JournalJournal of Pharmaceutical Analysis·TypeExperimental study·DateJun 8, 2022