Articles tagged with Biotechnology
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that fragrant essential oils can produce small, ultrafine byproducts called secondary organic aerosols (SOAs), causing eye and airway irritation. The study also revealed that spa layout and ventilation significantly affect indoor air pollutant levels during aromatherapy
Digna Biotech receives FDA approval for cardiotrophin-1 as an acute liver failure treatment. The medicine is expected to work by acting as a messenger to damaged liver cells, helping them recover and restoring function. Cardiotrophin-1 has been shown to stimulate hepatic regeneration and protect hepatocytes during acute hepatic damage.
Researchers discovered that cardiotrophin 1 accelerates fat elimination from adipose tissue, increases muscle fat burning, and improves glucose uptake in cells. Treatment of obese mice with cardiotrophin 1 also reduces food intake and corrects obesity and diabetes.
Scientists have made significant progress in developing effective delivery systems and efficient biomanufacturing strategies for DNA vaccines. Novel methodologies have emerged, including transdermal patches, electroporation, and plasmid purification techniques.
Advances in nanotechnology are driving innovation in mass spectrometry instrumentation, enabling faster and more precise biomarker validation. Researchers have developed novel nanoflow separation methodologies that ramp up the speed and precision of validating biomarkers.
Researchers at Ruhr-University Bochum have successfully removed a molecular switch in cyanobacteria that prevents premature breakdown of energy reserves. This allows for the use of excess energy for biotechnological purposes, such as hydrogen production.
Researchers at Ben-Gurion University developed a new test that distinguishes between bacterial and viral infections by measuring chemiluminescence. This timesaving method has predictive diagnostic value and could reduce antibiotic misuse and healthcare costs, as well as provide more accurate treatment.
A study found that broken compact fluorescent light bulbs continuously release mercury vapor for weeks to months, posing a risk of exceeding safe human exposure levels. The authors recommend rapid removal and suitable packaging to minimize the risk of breakage and retain Hg vapor.
Recent developments in protein kinase inhibitors include innovative drug development paradigms, improved inhibitor profiling, and expanded disease targets such as Alzheimer's disease. Researchers are focusing on inactive kinase states and using selectivity strategies to overcome obstacles in the field.
Researchers from top institutions receive awards for their work on ligand-binding assays, biotechnology innovations, and cancer treatment delivery. The American Association of Pharmaceutical Scientists recognizes excellence in these areas.
Dr. Arthur D. Levinson is recognized for his leadership and extraordinary achievements in cancer research, leading to targeted drugs and personalized healthcare. He was a key figure in developing cancer therapeutics, including Herceptin, Avastin, and Rituxan.
Researchers found that blue-green algae may produce an estrogen-like compound, disrupting reproductive hormones and affecting fish, plants, and human health. Exposure to the algal cells induced a response consistent with estrogen exposure in larval fish.
A computer model predicts the environmental fate and impact of oil and chemical dispersant in deepwater spills like the Gulf of Mexico incident. The tool will aid risk assessment and decision-making for scientists managing such disasters.
The University of Manchester is leading a €3.7m European Union-funded project to train the next generation of scientists in green manufacturing methods for the chemical industry. The 'BIOTRAINS' programme brings together experts from academia and industry to develop safer and less-environmentally damaging industrial processes.
Ingmar Riedel-Kruse's lab group developed video games where players influence the behavior of living microorganisms in real-time. These biotic games aim to educate people about basic biological processes and promote interest in biology, with potential applications in crowd-sourced research.
The top biotech acquisitions in 2010 that exceeded $1 billion included a $41 billion purchase of Alcon by Novartis, followed by a $18.5 billion bid for Genzyme from sanofi-aventis. Merck's $5.2 billion acquisition of Millipore and Teva's €3.625 billion purchase of ratiopharm also made the list.
A study published in PLoS ONE found that iota-carrageenan directly binds to influenza viruses, blocking attachment and spread. In animal experiments, it demonstrated equivalent efficacy to Tamiflu, offering a potential alternative for treating H1N1 influenza.
A recent roundtable discussion sponsored by GEN explored biological methods for improving marine environment understanding, assessing oil spill impact, and monitoring remediation. The event brought together scientists from academia and industry to discuss the effectiveness of these approaches.
Researchers at NYU's Courant Institute of Mathematical Sciences developed an algebraic model to predict DNA hybridization, enabling the monitoring of cell gene expression and genome characterization. The study provides a new tool for understanding biological systems and enhancing cancer and genetics research.
Climbers of Mount Kilimanjaro are at risk for Acute Mountain Sickness (AMS) due to rapid ascent rates. Prior acclimatization to increased altitude offers a significant protective effect against AMS, whereas prophylactic drug use or mid-climb rest days do not significantly reduce the risk.
A team of researchers has found a way to increase the number of blood-forming stem cells by using a unique stretchy surface. This breakthrough could revolutionize stem cell transplants by generating up to three times more stem cells than current methods.
Simon Cocklin, Ph.D., wins the ProteOn XPR36 Giveaway Program for his novel research applications for surface plasmon resonance technology. He plans to use the system in his lab and make it available to other researchers at Drexel University.
Experts warn that biotech companies in emerging economies are making innovative contributions to address health problems. They have brought affordable products to prevent, diagnose and remedy illnesses of local concern, but risk diverting focus from diseases of poverty as they grow in financial strength.
The biopharmaceutical industry is shifting towards more sustainable operations, with companies adopting environmentally friendly practices that also offer economic benefits. Key findings include the potential for waste reduction through process intensification and purification bottlenecks.
Researchers are leveraging decades-old ultrahigh pressure discoveries to advance proteomics, mass spectrometry, and protein extraction techniques. Pressure-cycling technology (PCT) accelerates glycan release, membrane protein extraction, and other complex processes.
Oil rig workers increasingly rely on telemedicine to receive medical attention due to limited access to healthcare. The use of technology enables real-time communication between nurses and emergency physicians, reducing response times and improving patient care.
The American Association of Pharmaceutical Scientists (AAPS) honored outstanding researchers with awards for their contributions to biotechnology. The Excellence in Ligand-Binding Assay Award and Innovation in Biotechnology Awards recognized achievements in fields such as drug detection, vaccine development, and cancer treatment.
A study found that south-south collaborations between biotech firms in developing countries are increasing, enabling the production of affordable health products. These collaborations have already led to successful vaccine development and distribution, such as the Brazil-Cuba collaboration during Africa's meningitis outbreak.
Singapore's A*STAR is collaborating with Italy's Siena Biotech to develop targeted therapies for gastric cancer, leukemia, and osteoporosis. The partnership aims to leverage advanced molecular biology and antibody engineering techniques to create novel treatments.
Smadar Cohen's groundbreaking research led to the development of an innovative cardiac scaffold that enhances mechanical strength and prevents enlargement of the left ventricle. The award recognizes her pioneering work in creating a resorbable liquid polymer, BL-1040, that promotes heart muscle recovery and repair.
Scientists have successfully grown and loaded empty nano containers with useful chemicals from a plant virus, opening up new areas of research in targeted drug delivery. The technology has potential applications in cancer treatment, delivering drugs directly to diseased cells while sparing healthy ones.
Maynard V. Olson receives the Promega Biotechnology Research Award for his development of orthogonal-field-alternation gel electrophoresis, yeast artificial chromosome (YAC) system, and sequence-tagged site (STS) mapping techniques. His work significantly contributed to the completion of the human genome map.
A Phase 2 trial showed that daclizumab combined with interferon beta reduced MS lesion formation by 72 percent compared to interferon beta alone. The treatment also increased a subset of natural killer cells, associated with a decrease in disease activity.
Epigenetics is recognized as a key factor in understanding complex biological variations. The February 1 GEN issue provides coverage of the latest research on histone modification, DNA methylation, and imprinting.
The Spanish biotechnology industry should focus on the food and plant sectors to remain competitive. However, a study found that these sectors have less clout than English-speaking countries due to limited research and development investment. The sector's growth is hindered by high costs of developing new medicines.
Advances in qPCR technology are expanding its applications in basic research and diagnostics, enabling more efficient detection and quantification of specific DNA sequences. Companies like Qiagen and Bio-Rad Laboratories are developing new methods to improve multiplex PCR and sample preparation.
Researchers have uncovered a complex heteromeric structure of the essential enzyme PPCDC in yeast Saccharomyces cerevisiae, composed of non-identical proteins. The discovery sheds new light on CoA biosynthesis and presents potential targets for antifungal therapy.
The BU School of Medicine's CityLab program has received a five-year, $1.3 million grant from the National Institutes of Health (NIH) to enhance its clinical research curriculum with hands-on laboratory experiments and computer-generated simulations.
Kyoto University Professor Sakayu Shimizu received the 2009 Enzyme Engineering Award for his pioneering contributions to biotechnological tools and novel microbial reactions. His research has led to the commercialization of many biotechnological processes on a large scale.
The 2009 Lasker Awards honor pioneering work in cancer and stem cell research, promising new therapies and a $700 million global market. Renowned scientists receive awards for their discoveries in nuclear reprogramming techniques and regenerative medicine.
A new study found that Canadian health biotech firms collaborating with developing countries have a strong interest in building partnerships, driven by access to emerging markets and cost savings. Joint R&D activities are nearly as common as distribution arrangements, reflecting bi-directional knowledge-intensive collaboration.
NGS technologies offer streamlined workflows, massive parallelism, and cost reduction through targeted sequencing of specific genes or regions. Researchers are applying NGS to various fields, including hereditary cancer research and bacterial gene expression studies.
The use of Twitter for healthcare communication offers numerous benefits, including fast and easy dissemination of time-critical information such as disaster alerts and drug safety warnings. However, caution is needed to preserve confidentiality and patient privacy in the clinical care setting.
Kelvin Lee, a prominent researcher in biochemical engineering, has been awarded the Biochemical Engineering Journal Young Investigator Award. He will receive a cash prize of $2,500 and present a lecture at the upcoming conference.
Professor Gregory Stephanopoulos has been awarded the 2009 Amgen Biochemical Engineering Award for his outstanding contributions to metabolic engineering. He has made significant contributions to the field of biochemical engineering, including the development of microbial cells for the production of fuels and chemicals.
A team of experts emphasizes the need for a comprehensive approach to science reporting, citing diminishing public trust in biomedicine and biotech research. The study proposes eight recommendations to enhance public understanding and confidence in scientific information.
Several companies, including Replikins and Novavax, are working on H1N1 vaccines with varying approaches. The need for a vaccine was prompted by the World Health Organization's Phase 5 pandemic alert.
The ACLU is challenging the patentability of two human genes linked to breast and ovarian cancer, alleging that gene patents stifle life science research. The organization claims that the patents are invalid and unconstitutional, with supporters arguing that they would harm patients and limit medical research.
Scientists discover that quinoline compounds inhibit S100A9's pro-inflammatory effects on white blood cells involved in immune regulation. This new mechanism may provide insights into the early stages of autoimmune disease development.
A novel digital gene-expression profiling technique is gaining traction, offering a fully quantitative approach to gene-expression analysis. The method has been shown to provide robust and comparable expression profiling data, making it an attractive alternative to traditional microarray-based platforms.
Dr Crouch, a 2009 Advancing BioBusiness Award winner, seeks to improve scientific discovery in Australia through state-of-the-art assays and automation. He hopes to develop new tests for bio-markers of diseases like cancer, improving the efficiency of research in Australian university laboratories.
The CellThera/WPI team will continue their joint efforts in regenerating mammalian muscle tissue under a one-year $570,000 DARPA contract. They aim to reprogram and engineer cells to replace damaged skeletal muscle and restore normal function.
The Madoff scandal has led to a shift away from risky investments, affecting endowment institutions and university research projects. Academic medical and bio-related research are tightening their belts as a result of the general economic situation.
Researchers at VIB confirm GPR3 protein's role in reducing amyloid plaques, a hallmark of Alzheimer's disease. The discovery paves the way for developing a new medicine to combat the disease and preserve brain cells.
Experts discuss new biotechnology techniques to remove fungus, micro-organisms, and insects from artwork, documents, and masonry, promoting natural and non-toxic preservation methods. Curators in developing countries face challenges in assessing vulnerability, improving storage conditions, and controlling environmental fluctuations.
A modeling study reveals that Katrina-flooded homes can harbor hazardous contaminants in the air, posing significant health risks to residents and first responders. The study identifies inhalation exposure routes through volatile and semi-volatile organic pollutants, highlighting the need for better preparation and safety protocols.
Researchers focus on microbes fermenting lignocellulosic biomass to produce bioethanol and biodiesel, reducing greenhouse gas emissions. Biofuel production requires a major effort in biochemical engineering to scale up and make it cost-effective.
Italian researchers measured particulate matter from natural gas domestic burners and found high concentrations in stove tops, emitting larger amounts of ultrafine particles. The study provides important insights into the environmental health consequences associated with common home appliances.
This year marks the 200th birthday of Charles Darwin and the 150th anniversary of the publication of his theory. Genetic Engineering & Biotechnology News is celebrating this milestone by interviewing leading researchers in evolutionary science, including experts on Darwin.
The US Air Force is integrating medical acupuncture into its military healthcare, utilizing a technique developed by Dr. Richard Niemtzow to relieve severe pain lasting several days. This approach reduces reliance on pain medications that may cause adverse reactions or addiction, offering a promising alternative for pain management in ...