Articles tagged with Biotechnology
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at the University of Helsinki discovered that cytoplasmic intermediate filaments interact with specific contractile actin filament structures called arcs, which transport intermediate filaments towards the nucleus. Disruption of these interactions leads to defects in cell morphogenesis and shape abnormalities.
Researchers discovered a specific immune cell type that reduces inflammation and protects against liver damage. The Ly6C-negative monocyte subset dampens the immune response and induces anti-inflammatory genes in nearby cells.
Scientists at the University of Eastern Finland have identified two separate sites on the protein NOS1AP that can be blocked to reduce damaging signals caused by NOS-1 in brain cells. This breakthrough could lead to the development of new drugs for neurological diseases such as stroke, chronic pain, depression, and anxiety disorders.
Researchers have successfully introduced a gene into foetal cells from Luxi Yellow cattle to increase the levels of beneficial omega-3 oils in beef. The study found that introducing the fat1 gene resulted in over five times higher levels of these fatty acids.
Researchers at Stanford have created a new field of interactive biotechnology that allows users to interact with living cells using games and remote-controlled labs. The team developed three projects: arcade-style kiosks, biotic games for teaching bioengineering devices, and robotic biology cloud labs.
Self-affirmations help level the playing field, reducing power differences in high-stakes situations. Writing down a self-affirmation can be more effective than just thinking it, boosting confidence and performance.
The $2.5 million funding package supports five health innovations in India, including mobile daycare centers for migrant construction workers' children and early childhood development programs. Grand Challenges Canada has partnered with the Indian government to accelerate efforts to eliminate visceral leishmaniasis in Bihar.
Researchers at the University of Manchester have created a synthetic pathway for biosynthesis of renewable propane, paving the way for its commercial production. The breakthrough uses an engineered enzyme variant to redirect microbial pathways, producing propane as a clean-burning alternative to fossil fuels.
A special focus issue in Nanomedicine examines the intersection of nanomedicine and regenerative medicine, showcasing advancements in nanotopography, nanofunctionalization, and stem cell research. The field of nanoregeneration has grown exponentially over the last 15 years, with potential applications in drug discovery and cell targeting.
Researchers at ETH Zurich have developed a novel biotechnological solution to treat erectile dysfunction by triggering reliable erections with gene therapy and blue light exposure. The system works similarly across all mammals, including humans, and is expected to have few side effects.
The Austrian Centre of Industrial Biotechnology has developed the world's first continuous purification method for recombinant antibodies from clarified CHO cultures. This breakthrough technology is expected to significantly reduce production costs for highly valued drugs, such as cancer treatments and autoimmune disease therapies. The...
Continuous bioprocessing is gaining consideration as a method of industrial bioprocessing, with potential advantages including lower costs and increased efficiency. Dr. Konstantin Konstantinov and Dr. Charles Cooney emphasize the need for methods to evolve around this new platform.
Researchers at Helmholtz Center for Environmental Research have found that bioelectrochemical processes promise improved yields and can be economically competitive. The technology has the potential to save costs of up to 18% in EU and US markets, with estimated savings over a ten-year horizon reaching $50 million.
The National Collection of Yeast Cultures has added the 4,000th yeast strain to its collection, including a novel species found in Ecuador's Yasuní National Park. This discovery expands microbial biodiversity and offers new possibilities for sustainable biotechnology.
Scientists at TU Dresden have presented a novel method, real-time deformability cytometry (RT-DC), to mechanically screen large populations of cells quickly and accurately. This technology enables the continuous, on-the-fly mechanical screening of hundreds of cells per second.
A study reveals enzymatic hydrolysis and drying significantly alter lignocellulosic biomass nanostructure, reducing pore volume by up to 80%. The accessible reaction space is also reduced, hindering hydrolysis. This work sheds light on the importance of physical features in defining hydrolysis rates.
A new study published in Journal of Neurotrauma found that existing models for predicting outcomes after mild traumatic brain injury perform poorly. The study identified older age, pre-existing psychiatric conditions, and less education as the strongest predictors of poor outcomes after mTBI.
Researchers from CU School of Medicine and Taiga Biotechnologies have discovered a way to expand production of stem cells used to treat cancer patients. This breakthrough technology could also be used to treat inborn immunodeficiency conditions, metabolic diseases, and autoimmune disorders.
A new study reveals that better communication of basic research results during the discovery stage can lead to faster commercialization. Biotech firms often give up on inventions and transfer technology to other firms for repurposing in a new disease category, causing time losses earlier in the pathway.
The 2014 World Stem Cell Summit will bring together leading scientists, business leaders, and regulators to discuss the future of regenerative medicine. The summit will feature over 200 prominent speakers from more than 40 nations, exploring the latest scientific discoveries and innovative business models.
The Festschrift issue honors Dr. Koprowski's pioneering work on vaccines, including the oral polio vaccine, and its impact on cancer biology research. Dr. Koprowski's achievements have been recognized by CASIS, which enabled visionaries to explore life science research in microgravity environments.
Amunix is presenting unpublished data on its XTEN half-life extension technology, which extends the half-life of biologically active molecules via chemical conjugation. The technology has been used to extend the half-life of genetically fused therapeutic proteins and peptides.
Elsevier has launched an open-access journal, Computational and Structural Biotechnology Journal (CSBJ), on behalf of the Research Network of Computational and Structural Biotechnology. The journal publishes high-quality research articles and reviews in computational biotechnology, with a focus on mechanistic understanding through appl...
Researchers are developing a new, freeze-stable tetanus vaccine using lipid nanoparticles and a hollow microneedle system. The delivery device can target specific areas of the skin, increasing vaccine efficacy.
Scientists suggest that every town could have a small-scale cultured meat factory, producing sustainable and cruelty-free meat alternatives. The production process involves taking stem cells from cell banks and using them to create minced meat cakes.
Researchers at Cedars-Sinai Medical Center will conduct a Phase II clinical trial to evaluate the safety and efficacy of 3K3A-APC, an experimental drug combining with rtPA to treat ischemic strokes. The study aims to reduce risks and improve outcomes for stroke patients.
A new paper from Rice University's Baker Institute calls for revised patenting guidelines to address the broad patent landscape in biotechnology. The authors suggest initial steps to reform patent licensing and require detailed patent descriptions to prevent costly lawsuits.
The 2014 AAAS/Subaru Science Books & Film competition recognized four engaging science books exploring school gardens, fossil discovery, backyard bird watching, and biotechnology. Winners received $1500 and a plaque for their outstanding contributions to science writing and illustration.
Tel Aviv University researchers developed a computer algorithm that predicts which genetic genes are lethal to cells when overexpressed. The new algorithm, called Expression Dependent Gene Effects (EDGE), helps guide metabolic engineering to produce new chemicals in more efficient ways.
The UK's Biotechnology and Biological Sciences Research Council has launched 13 unique collaborative networks to promote interaction between academia and industry, pooling skills to develop research projects with potential to overcome major challenges in industrial biotechnology and bioenergy. The networks will unlock innovative ways t...
A new study finds that an experimental drug called 3K3A-APC reduces brain damage and eliminates brain hemorrhaging in stroke-afflicted mice and rats. The drug extends the therapeutic window of FDA-approved clot-busting therapy tPA, counteracting its tendency to induce bleeding.
Genome researchers at Bielefeld University have successfully sequenced the Chinese hamster genome, providing valuable data for biopharmaceutical production. The decoded genome consists of eleven pairs of chromosomes and is comparable in magnitude to the human genome.
University of Illinois bioengineers find way to permanently modify silicone polymer surface with organic material, resulting in stable adhesion for several months. The method enables practical applications in cell culture platforms, microfluidic devices, and tissue engineering.
The 2013 World Stem Cell Report will be published as a special supplement to the peer-reviewed journal Stem Cells and Development. The report delivers an orbital and unique viewpoint on regenerative medicine, featuring content from leading policy-makers, regulators, and experts.
Researchers have developed a novel vaccine delivery system that mimics pathogens to stimulate the immune system without causing infection. The technology uses inulin acetate from plant fibers, showing promise for preventing viral diseases such as influenza, with an estimated cost of one or two dollars per dose.
The India-developed rotavirus vaccine ROTAVAC has demonstrated excellent safety and efficacy in a Phase III clinical trial, reducing severe rotavirus diarrhoea by over half. The vaccine's impact extends beyond rotavirus infections, also showing protection against severe diarrhoea of any cause.
This year's AAPS National Biotechnology Conference award winners have made significant contributions to the field of biotechnology, including the development of novel drug delivery systems and innovative approaches to protein-matrix interactions. The awards recognize excellence in research, innovation, and education.
The researchers are being honored for their contributions to the discovery and applications of optogenetics, a technology that allows scientists to control brain activity by genetically engineering neurons. Hundreds of labs have started using the technique to manipulate brain activity in experimental animals.
A team of international researchers has created an instruction manual for the human genome, providing a framework to understand the relationship between genetic makeup and lifestyle. The model explains how individual biological parts operate differently within each person, paving the way for tailored treatments in personalized medicine.
Researchers John Wong, Ronald Berger, and Hien Nguyen receive awards and funding to develop life-saving technologies. The Life Prizes aim to accelerate the translation of promising research into commercial applications, speeding up the delivery of innovative medical solutions.
The hepatitis B virus X protein (HBx) represses microRNA-148a, leading to increased levels of the oncogenic protein HPIP and subsequent oncogenic transformation in liver cancer. This study demonstrates a cancer-associated virus promoting carcinogenesis through direct manipulation of a microRNA.
Researchers have discovered that the penicillin-producing fungus Penicillium chrysogenum reproduces sexually through a two-gender cycle. This leads to strains with new properties, including high penicillin production without contaminating genes.
Douglas Kell, a University of Manchester professor, was elected a Fellow of the American Association for the Advancement of Science (AAAS) for his work in quantitative and systems biology and analytical biotechnology. He is one of fewer than 50 UK scientists to hold this honor, and will receive an official certificate and pin at the AA...
Researchers successfully engineered Arabidopsis plants to reduce xylan content and improve breakdown of carbohydrate into simple sugars. The resulting plants exhibit improved saccharification properties, allowing for better production of biofuels from plant biomass.
Researchers discovered a gene called Taqpep that helps establish periodic patterns like stripes or spots in felines. Variations in the Edn3 gene are responsible for dark hair color, suggesting a link between genetic mechanisms and animal coat patterns.
The agreement aims to disseminate scientific knowledge from Asian research communities globally, promoting international cooperation in biotechnology and engineering. Representatives from the AFOB will join the editorial board, contributing special issues and news to Wiley's journals.
Researchers at Scripps Research Institute and Sea Lane Biotechnologies discovered an unusual antibody, C05, that can neutralize various flu viruses by targeting the receptor binding site. The unique antibody uses only a single loop to grab this site, making it potentially useful for developing universal flu vaccines and therapies.
Biotech Boulevard features companies making a mark on the global bioindustry through novel therapeutics and technologies. The microsite provides a platform for discovery, investment, and collaboration among these promising young companies.
Research on Alzheimer's disease is gaining momentum, with over 150 companies working on innovative approaches to tackle the debilitating disease. New therapies, such as Antisenilin and Gammagard, are in Phase III trials and show promise in addressing the underlying biology of the disease.
A study published in Therapeutic Hypothermia and Temperature Management found that therapeutic hypothermia can limit the devastating consequences of brain injury after cardiac arrest. The survey results show a wide variation in patient selection criteria for therapeutic hypothermia across New Jersey hospitals.
Researchers have developed a new experimental drug that reduces brain damage and improves motor skills in stroke-afflicted rodents. The drug, 3K3A-APC, extends the therapeutic window of tPA, allowing for more effective treatment beyond the three-hour time frame.
The tissue engineering and stem cell industries have experienced significant growth, with over half of companies generating revenue, up from 21% four years ago. Commercial products and services are driving the increase, with $3.5 billion in sales revenues and industry spending approaching $3.6 billion.
Researchers developed two somatostatin vaccinations that reduce body weight and increase energy expenditure in diet-induced obese male mice. The vaccines induce antibodies to somatostatin, effectively removing inhibition on growth hormone and insulin-like growth factor-1.
The inaugural issue of Disruptive Science and Technology explores new paradigms in scientific publishing, treatments for sepsis, and temperature regulation, among other topics. The journal provides a custom-designed forum for world-class papers that challenge the status quo and bring about new innovations.
Mixing herbal supplements with medications can lead to increased risk of bleeding, decreased blood sugar, hormonal effects, and elevated blood pressure. Clinicians must educate their patients about these risks and interactio ns.
A high level of skill and knowledge is necessary to optimize patient outcomes in bariatric surgical patients. The journal Bariatric Nursing and Surgical Patient Care emphasizes the need for consistent care with current evidence and best practices.
A national evidence-based paradigm for faith-based advocacy to prevent childhood obesity has been developed. The link between advocacy and policy is crucial in promoting healthy lifestyles and routine physical activity among children. The article highlights the importance of faith-based organizations in this campaign.
A new wireless sensor device can detect high concentrations of E. coli bacteria in under 1 hour and lower concentrations in less than 8 hours. This rapid detection system has the potential to serve as an early warning tool for beach safety, providing a more timely response to fecal contamination.
A team of four early-career researchers from the University of Oxford emerged as winners of this year's Biotechnology Young Entrepreneurs Scheme (YES) competition. They impressed investors with their idea for using yeast to produce high-value fragrance components. The competition aims to raise awareness of commercialization amongst bio...
FlexGen's DNA-sequencing technology helps identify genetic causes of diseases and adapts treatment. The company is now working on new technologies to introduce to the market, aiming to understand diseases at their core.