Articles tagged with Biotechnology
A phase III study shows that HLX02, a Chinese-made biosimilar of trastuzumab, has an overall response rate of 71% at week 24, comparable to the reference medication. The treatment is safe and effective, with similar rates of adverse events and no differences in safety profiles or immunogenicity.
Researchers at Chalmers University of Technology have developed a new nanoreactor that allows them to map catalytic reactions on individual metallic nanoparticles, enabling the design of more effective catalysts. This breakthrough could lead to significant improvements in chemical processes and the creation of more sustainable technolo...
ORNL's Dan Jacobson and team designed algorithms to improve crop resilience to climate change. The AI technology enhances crop yields under variable weather conditions.
Asrar Damdam, a KAUST Ph.D. student, has developed a silicon-based platform that can change shape and stretch in various directions, exceeding human skin's 20% stretchability limit. Her design has potential for integration into wearable electronics devices and soft robotics.
A new study found that children of fathers with poor mental health have a higher risk of poor mental health and overall health, highlighting the significant role fathers play in their children's well-being. The researchers emphasize the need for interventions to improve father involvement in children's lives.
The company has proposed a new family of prior distributions: TRIP, which improves Fréchet Inception Distance for GANs and Evidence Lower Bound for VAEs. The model was experimentally validated in cells and animals, demonstrating its potential for accelerating drug discovery.
A pioneering clinical trial will assess the safety and efficacy of cannabidiol (CBD) in alleviating hallucinations and delusions associated with Parkinson's-related psychosis. The study aims to determine whether CBD can correct abnormal brain functioning and improve quality of life for affected individuals.
A new study at the University of Copenhagen reveals that bacteria prioritize cooperation over competition, leading to stronger and more resilient communities. This discovery challenges Darwin's theory of evolution and has significant implications for biotechnology and disease treatment.
Researchers at Stanford University and the Exploratorium developed an immersive exhibit allowing visitors to interact with single-cell organisms called Euglena. Visitors spent twice as much time engaging with interactive exhibits compared to traditional microscope-only displays.
Researchers at the University of Portsmouth have created a biosurfactant using rice straw, providing a natural replacement for chemical surfactants in household products. The process is environmentally friendly and cost-efficient, with potential applications in various industries.
Researchers have uncovered a new mechanism for tooth repair by identifying a new population of mesenchymal stromal cells that contribute to dentin formation. These cells send signals to control cell production through the molecular gene Dlk1.
A research team has elucidated the complex degradation pathway of the polysaccharide Ulvan from marine algae, revealing the biochemical function of 12 enzymes. The findings have significant implications for future biotechnological applications and improve our understanding of the marine carbon cycle.
Parkinson's UK is partnering with NRG Therapeutics to develop a potential drug that could safeguard dopamine cells and slow down the progression of Parkinson's. The partnership will support the identification of novel molecules to protect mitochondria within dopamine-producing cells.
A broadly effective dengue vaccine is still a substantial challenge due to the disease's complexity. However, experts suggest that rethinking existing concepts and developing live attenuated vaccines could lead to more effective solutions.
GlycoNet researchers Drs. Alexey V. Pshezhetsky and Christopher Cairo have been awarded half a million dollars to advance research on human neuraminidase inhibitors for treating cardiovascular and autoimmune diseases. The funding will support the development of novel treatments for these complex diseases.
The Massachusetts Medical Device Development Center's $200K Challenge recognized innovative medical device solutions for treating blood clots, congestive heart failure, and other conditions. The competition drew entrants from around the world and awarded shares of a $200,000 purse to 12 winners.
Biotechnologists and medical researchers at FAU have developed a miniaturized multi-photon microscope that can be used in endoscopes, illuminating the body's own molecules to enhance imaging. This technology offers high-resolution three-dimensional images of living tissue, supplementing or even making biopsies superfluous.
Research finds that high levels of hygiene promote resistance to antibiotics, with microbiome diversity decreasing in areas with strict controls. Regular measures such as airing, houseplants, and reducing antibacterial cleaning agents may counteract this trend.
Researchers at IBS have identified the mistake-rate of DNA editing tools using CRISPR and adenine base editors. The study reveals that ABE7.10, a widely used gene engineering tool, has an average of 60 off-target mistakes in the human genome.
Artist Heather Dewey-Hagborg collaborated with scientists to create a custom virus that increases oxytocin production, associated with feelings of love and empathy. The 'Lovesick' virus is a harmless, non-replicating vector that expresses the hormone oxytocin and a fluorescent protein, allowing cells to glow bright red.
A new computational method called CATCH enables scientists to design molecular probes that can capture genetic material of various microbes, including viruses. This approach has been successfully tested in detecting low-abundance viruses like Zika, improving the detection of viral content in clinical samples.
Researchers from UTokyo and RIKEN developed a device that performs logic operations using electric fields and UV light. The device has the potential to create less heat and power consumption than current semiconductor chips.
Researchers have developed a prosthetic arm that can detect and replicate phantom limb movements, revolutionizing amputee rehabilitation. The device uses muscle activity generated by mobilization of the phantom limb to achieve precise control, allowing patients to interact with their prostheses without extensive training or surgery.
Researchers have purified and visualized the Cyclic Electron Flow supercomplex, a critical part of photosynthetic machinery, to advance solar-powered microalgae-based biotechnologies. This discovery provides new insights into how plants capture and store solar energy at the molecular level.
Researchers at Ural Federal University developed new adsorbents and enzymatic catalysts using modified halloysite nanotubular materials with unique functional properties. The breakthrough technology enables cost-effective extraction of non-ferrous metals and efficient biotechnological hydrolysis processes.
A new machine-learning algorithm, Best Match, has been introduced to improve the search results in PubMed, the world's largest biomedical literature database. The algorithm draws on user responses and click-through rates to provide more relevant results, increasing the click-through rate by 20% compared to chronological ordering.
A new AI model, CytoReason, has created the largest library of inter-cellular communications, mapping over 3,000 previously unlisted cellular interactions. This analysis provides valuable clues for drug development and sheds light on immune system dynamics.
Professor Lee recognized for his work on metabolic engineering to develop sustainable chemical materials, with notable research in drug-drug and food interactions using AI and novel enzymes. He is the second Asian recipient of the prestigious award, honoring Professor Peter V. Danckwerts.
Bielefeld chemists create a biocatalytic method to selectively reduce sulfur-containing heterocycles, yielding highly enantioselective synthesis of target compounds. The discovery has potential applications in developing new active substances and sustainable pharmaceutical production.
Researchers at IU School of Medicine are working on printing 3D pig liver tissue for xenotransplantation research. The collaboration with Lung Biotechnology aims to accelerate the development of unlimited organs for life-saving transplants.
Researchers have developed an AI algorithm that can accurately predict biological age and mortality risk using wearable sensor data from a large dataset. The model outperforms previous models and has the potential to refine health risks for life and health insurance programs.
The Osher Collaborative for Integrative Medicine has launched a new quarterly column in JACM, discussing strategies to advance health justice through integrative medicine principles. The inaugural column highlights the need to address bias and discrimination in intrapersonal attitudes and behaviors.
Researchers review hypothetical uses of biosurfactants, safe and affordable molecules that can produce effective detergents at low temperatures. They have potential applications in industries such as biodiesel production and natural gas harvesting from ice crystals.
Parkinson's UK is providing over $1 million in funding to Neurolixis to accelerate the development of a promising new drug for people with Parkinson's. The project aims to address L-DOPA-induced dyskinesia, a disabling side effect of long-term L-DOPA treatment.
The World Health Organization has prequalified the India-made rotavirus vaccine ROTAVAC, which will be available for procurement by UN agencies and Gavi for use in low-resource countries. The vaccine is the result of a unique social innovation partnership between Indian and international researchers, public, and private sectors.
The team built larger objects, including gears for nanomotors and microtubes with sizes comparable to bacteria. They also constructed closed cage structures with discrete-size cages attaining molecular weights and sizes comparable to viruses and small cell organelles.
Biologists found a new substance, isocitric acid, with anti-oxidant properties that increased the survival rate of infusoria by 25-31 times compared to untreated cells. The compound also surpassed the effects of ascorbic acid, offering a promising solution for protecting living organisms from various toxic compounds.
The shift from public to private funding in biomedical research poses significant challenges, including collaborative research models, intellectual property rights, and oversight. Researchers must navigate conflicts between private benefactors, institutions, and scientists to ensure the integrity of research.
A new review article examines the effectiveness of lipid-based products, including liposome lid sprays and emulsion eye drops, in treating dry eye disease. The studies found that these products provide immediate relief of symptoms and improve the structure and stability of the tear film lipid layer.
The new eMAGE method eliminates DNA breakage errors, enabling efficient genetic modifications with high accuracy. This technology has the potential to revolutionize disease treatment, antibiotic production, and industrial biotechnology applications.
Researchers at Bielefeld University's CeBiTec are developing novel methods to produce sustainable compounds using microorganisms, aiming to replace fossil fuel resources in the long term. The center has received €4.8 million in funding for three international cooperative research projects.
A new study found that 89% of Hispanic women and 81% of non-Hispanic white women use herbal remedies. However, only a third of white women and less than 1 in 6 Hispanic women discuss their use of herbal treatments with doctors.
Researchers from TU Graz developed the 'Lipid Data Analyzer' tool, which can identify lipids at a detailed structural level more precisely and reliably than previous solutions. The tool detected over 100 novel lipid species and can be flexibly adapted for other metabolic products such as sugars.
Researchers have successfully tested a pre-industrial laboratory scale method using microorganisms as natural antagonists to eliminate up to 99.6% of germs from hatching eggs. The bacteria producing pyrazines demonstrated efficiency comparable to that of formaldehyde fumigation.
Researchers discovered oxidative enzymes that work together with hydrolytic enzymes to break down cellulose. The study observed these enzymes on the surface of cellulose particles using atomic force microscopy, providing direct evidence of their activity.
Researchers at Goethe University Frankfurt develop a new mechanism to channel metabolism in baker's yeast, enabling direct delivery of raw materials to desired enzymes. This approach improves sugar conversion into ethanol while minimizing unwanted by-products.
Dr. Richard McIndoe receives $12.8 million grant to continue leading a national research initiative focused on diabetic complications, including nerve and kidney damage, high blood pressure, cardiovascular disease, and stroke. The consortium supports short-term studies and summer programs for medical students.
The UH biotech program will expand to five colleges and universities nationwide, implementing its innovative approach to integrating classroom instruction and research. The program aims to demonstrate its effectiveness across various higher education institutions and has the potential to address real-world issues such as environmental ...
The article explores de-extinction efforts, highlighting potential ecological benefits and challenges. Experts debate whether de-extinction initiatives aid or hinder conservation efforts, with concerns about habitat destruction and climate change.
The symposium, The Architects of Aging, brings together leaders in biotechnology and biomedical research to target the underlying mechanisms of aging. Experts will present cutting-edge interventions that aim to modify biological processes of aging, with a focus on extending healthspan.
Researchers have discovered how Cpf1, a new molecular scissor, can act like a GPS to identify its destination in the genome, enabling precise genome modification and repair. The high precision of Cpf1 will improve the use of this technology in repairing genetic damage and other medical applications.
Research suggests that inferior synthetic horns can drive out wild horn suppliers through adverse selection, reducing poaching and driving down prices. Nonprofits could play a key role in producing these synthetic horns, promoting competition and increasing market supply.
Douglas Wallace receives the award for his pioneering work in mitochondrial genetics, leading to insights into human genealogy and implications for treating metabolic and degenerative diseases. The recognition acknowledges the crucial role of mitochondrial DNA genetics and bioenergetics in common disease etiology.
Professor Tyagi received the Outstanding Scientist Award from the International Bioprocessing Association for his outstanding contribution to environmental biotechnology. He has also earned numerous accolades, including awards from the American Academy of Environmental Engineers and Scientists.
Professor Sang Yup Lee was elected as a foreign associate to the US National Academy of Sciences (NAS) and previously to the US National Academy of Engineering (NAE). He is the first Korean to be elected to both prestigious academies, recognized for his leadership in microbial biotechnology and metabolic engineering.
The Moscow State University has opened a new cryobank to store biotechnological plant material, including rare species cell cultures. The facility aims to prevent cross-contamination by storing biological samples in nitrogen vapor, not liquid nitrogen.
A new study found that health insurance reimbursement for complementary healthcare services is significantly lower than for primary care physicians. The likelihood of reimbursement was 69% lower for acupuncturists, 71% lower for chiropractors, and 62% lower for doctors of naturopathic medicine.
Scientists discovered a caterpillar can break down polyethylene, a tough plastic found in shopping bags. The wax worm's saliva contains an enzyme that degrades the chemical bonds in the plastic, reducing its mass by 92mg after 12 hours.
Researchers have found a way for a caterpillar to break down polyethylene, a common type of plastic. The larvae of the Galleria mellonella moth can digest and chemically transform polyethylene into ethylene glycol, offering a potential solution to managing plastic waste.
The American Telemedicine Association has published new guidelines to improve remote stroke care using telemedicine communication technologies. The guidelines describe the network of audio-visual communication systems and computer systems needed to link an expert stroke team with a remote patient, aiming to rapidly diagnose and treat i...