Articles tagged with Protein Design
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at Northwestern University create a new method to produce nanowires with controlled gaps, enabling the design of devices for diagnostics and drug discovery. The technique, called on-wire lithography, allows for the fabrication of nanowires with precise electrical measurements on individual molecules.
A team of researchers from Howard Hughes Medical Institute and the University of Washington designed a novel protein with atomic-level accuracy using computer-aided design. The breakthrough allows for the exploration of previously unseen regions of the protein universe, opening up new possibilities for studying protein-folding energetics.
Duke University Medical Center biochemists have successfully engineered a protein that can detect nerve agents like soman and sarin. The proteins could be incorporated into detectors, resembling smoke detectors, to provide early warning and monitor levels.
Scientists successfully designed and built an artificial protein using a novel computational approach, opening up new possibilities for medicine and industrial applications. The achievement represents a significant breakthrough in understanding protein folding and design.
Princeton University professor Hecht invents a technique to make protein molecules from scratch with various shapes and compositions. The method involves designing amino acid sequences that fold like natural proteins, potentially leading to the creation of custom-designed proteins for new drugs and industrial processes.
Krishna Kumar, an associate professor of chemistry at Tufts University, has been recognized for his innovative protein design and engineering research. His work on 'decorating' proteins with Teflon-like materials has potential medical applications in drug delivery and antibiotic design.
Researchers developed a novel computer protein design method that created a more efficient and stable version of the peptide Compstatin, which prevents autoimmune-mediated damage. The new method cut down on trial and error, allowing for faster development of potential biopharmaceuticals.
Researchers at Duke University have successfully redesigned sensor proteins that can detect a range of molecules, including explosives like TNT and neurotransmitters. This breakthrough could lead to new technologies for monitoring diabetes and locating underwater robots.
Duke University biochemists create sensor proteins that can specifically detect TNT and other chemicals, opening doors for medical and environmental applications. The researchers' computational design method narrows down possible structures to reasonable numbers with days' worth of calculations.
For the first time, researchers have designed a working molecular motor that can convert chemical energy into controlled motion. This breakthrough advances miniaturization technology to the single molecule level, with potential applications in understanding diseases and developing new treatments.
Andrew Hamilton, an organic chemist at Yale University, is being honored with the American Chemical Society's Arthur C. Cope Scholar Award for his work on designing molecules that can control cell growth in cancer treatment. His research focuses on targeting a protein called Ras, which accounts for over 30% of all cancers.
Six university teams will showcase their innovative food products, including Sweet Spots, Jammm Singles, and Tater Stuffs. The teams will compete for top honors based on product originality, feasibility, innovativeness, and market potential.
Researchers at the University of Pennsylvania have created the largest protein from scratch, inspired by a household bacteria. The protein, called alpha-3D, has a well-defined three-dimensional structure and could lead to novel drugs and diagnostic tools.
Researchers successfully engineered a hybrid enzyme with improved substrate specificity, demonstrating the potential of recombining subdomains to generate novel functions. The study presents a method for generating hybrid genes by combining subdomain segments from diverse proteins.
Scientists at UC Berkeley designed a protein that toggles between two structures upon binding a small molecule, enabling detection of carcinogens like benzene. The newly designed protein could also be used as a molecular switch or zipper to join proteins together.