Researchers at UC San Diego report new direct evidence of atrophy and fibrosis in pelvic floor muscles of women with symptoms of pelvic organ prolapse. They also showed that an acellular injectable skeletal muscle extracellular matrix hydrogel reduces the negative impact of simulated birth injury on rat pelvic floor muscles.
SourceUniversity of California - San Diego·JournalScience Translational Medicine·TypeExperimental study·DateAug 2, 2023
A University College Dublin researcher has received a European Research Council Proof of Concept grant to investigate the disruptive power of macromolecular crowding in cell culture systems. The project aims to develop novel approaches for regenerative medicine by accelerating tissue development and improving therapeutic potential.
Researchers at Harvard developed a fiber-infused ink that allows 3D-printed heart muscle cells to align and contract like human heart cells, enabling the creation of functional heart ventricles. The innovation can be used to build life-like heart tissues with thicker muscle walls, paving the way for regenerative therapeutics.
SourceHarvard John A. Paulson School of Engineering and Applied Sciences·JournalNature Materials·DateJul 27, 2023
A team from Tokyo Medical and Dental University has developed a technique to improve bone regeneration over large areas in rats, using vascular endothelial growth factor (VEGF) and Runx2. The combination of these two RNAs led to better regenerative responses in bone cells than each RNA alone.
SourceTokyo Medical and Dental University·JournalInflammation and Regeneration·DateJul 25, 2023
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers from Tokyo Medical and Dental University successfully generated functional parathyroid glands from mouse embryonic stem cells using blastocyst complementation. This breakthrough study demonstrates the potential for regenerating organs in vivo and provides a new treatment option for hypoparathyroidism.
SourceTokyo Medical and Dental University·JournalProceedings of the National Academy of Sciences·DateJul 24, 2023
Hematopoietic stem cell culture technology improves genome editing in HSCs by increasing successful correction rates to 100%, eliminating genetic mutations, and enhancing cell transplantation outcomes. This breakthrough enhances the efficiency and safety of gene editing in treating genetic diseases.
SourceUniversity of Tsukuba·JournalCell Stem Cell·DateJul 10, 2023
A recent study elucidated the role of EGF and its downstream signaling cascade in controlling oral keratinocyte behavior, offering new insights for pharmacological manipulation. The findings suggest that activating the EGF/EGFR pathway can enhance oral keratinocyte motility and proliferation.
SourceNiigata University·JournalFEBS Open Bio·DateJun 29, 2023
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DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A novel study found that honokiol promotes healing of rotator cuff injury and may be an effective treatment for humans. The study suggests that SIRT3 activation plays a protective role in alleviating aging-induced fibrocartilage degeneration and promoting rotator cuff healing.
SourceElsevier·JournalAmerican Journal Of Pathology·TypeExperimental study·DateJun 20, 2023
Recent innovations in volumetric bioprinting by UMC Utrecht researchers enable faster and more clinically relevant printing of living tissues. By controlling chemical properties, the team creates smart materials that guide cell behavior and development, mimicking native biochemical environments.
SourceUniversity Medical Center Utrecht·JournalAdvanced Materials Technologies·DateJun 12, 2023
Researchers at the University Medical Center Utrecht combined volumetric bioprinting and melt electrowriting to create functional blood vessels. The technique allowed for the creation of tubes, forked vessels, and even venous valves with unidirectional flow, paving the way for further development into a fully functional blood vessel.
SourceUniversity Medical Center Utrecht·JournalAdvanced Materials·TypeExperimental study·DateJun 7, 2023
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Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers at UMC Utrecht successfully merged two printing techniques to create functional tissues made from stem cells. Granular biogels enable high cell density, survival, and specialization, surpassing solid gels. This breakthrough boosts tissue functionality and opens up opportunities for regenerative medicine.
SourceUniversity Medical Center Utrecht·JournalAdvanced Materials·TypeExperimental study·DateJun 7, 2023
A team of researchers found that a small population of nerve cells exists in everyone that could be coaxed to regrow, potentially restoring sight and movement. The discovery provides new insights into how axons grow and could lead to effective therapies for blindness, paralysis, and other disorders caused by nerve damage.
SourceUniversity of Connecticut·JournalDevelopment·TypeExperimental study·DateMay 31, 2023
Biomedical engineers at UTS have developed an intervertebral disc-on-a-chip, a precision-engineered toolbox for low back pain studies. The device simulates the complex mechanobiology of native tissue, enabling accurate evaluation of experimental methods for treatment or regeneration.
SourceUniversity of Technology Sydney·JournalTrends in Biotechnology·TypeComputational simulation/modeling·DateMay 28, 2023
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A new method for producing biocompatible microfibres with controlled size and shape has been developed at Graz University of Technology, significantly accelerating production and reducing costs. This breakthrough enables the potential for accelerated production of autologous skin and organs, which could be a game-changer for burn victi...
SourceGraz University of Technology·JournalPhysical Review Applied·TypeExperimental study·DateMay 26, 2023
Scientists adapted volumetric bioprinting to create three-dimensional, biologically functional areas within printed gels. The technique enables the infusion of biomolecules and growth factors into gelatin structures, creating a chemical map that guides cells to develop or specialize accordingly.
SourceUniversity Medical Center Utrecht·JournalAdvanced Materials Technologies·TypeExperimental study·DateMay 23, 2023
Scientists have developed a new method to deliver genetic information to stem cells using nanoparticles coated with a specific polymer, enabling more efficient control over cellular differentiation. This innovation has the potential to improve the efficiency and effectiveness of regenerative medicine treatments.
SourceXi'an Jiaotong-Liverpool University·JournalNano Letters·TypeExperimental study·DateMay 8, 2023
Researchers created a promising injectable cell therapy that reduces inflammation and regenerates articular cartilage in osteoarthritis patients. The treatment was tested in a pre-clinical model and showed ability to reverse cartilage damage and diminish inflammation.
SourceAtrium Health Wake Forest Baptist·JournalScience Advances·TypeExperimental study·DateApr 21, 2023
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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Cedars-Sinai investigators have discovered a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using human induced pluripotent stem cells. The new approach uses cells derived from iPSCs that are renewable, scalable, and can delay disease progression in rodents.
SourceCedars-Sinai Medical Center·JournalStem Cell Reports·DateApr 20, 2023
Scientists have developed a method to activate protein functions using brief flashes of light, enabling precise control over when and where chemical reactions occur. This technology has potential uses in tissue engineering, regenerative medicine, and understanding biological processes.
SourceUniversity of Washington School of Medicine/UW Medicine·JournalNature Chemistry·TypeExperimental study·DateApr 17, 2023
Researchers developed a novel approach that promotes bone regeneration in mice without implantation of bone tissue or biomaterials. By carefully stretching the skull along its sutures, they activated skeletal stem cells that reside in these wiggly seams, repairing damage to the skull that would not have healed on its own.
SourceUniversity of Pittsburgh·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateApr 14, 2023
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Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers at the University of Washington School Medicine have engineered stem cells that do not generate dangerous arrhythmias. These 'MEDUSA' cardiomyocytes can engraft in the heart, mature into adult cells and beat in sync with natural pacemaking without generating dangerous heart rates.
SourceUniversity of Washington School of Medicine/UW Medicine·JournalCell Stem Cell·TypeExperimental study·DateApr 6, 2023
Researchers at TUM have developed a method to create mini-hearts in Petri dishes using stem cells. The resulting organoids mimic the earliest stages of human heart development and can be used to investigate congenital heart defects, potentially leading to new treatment methods.
SourceTechnical University of Munich (TUM)·JournalNature Biotechnology·TypeExperimental study·DateApr 4, 2023
Researchers at Sanford Burnham Prebys have identified a group of proteins called AJSZ that help solve a known problem in cellular reprogramming. By blocking the activity of these proteins, they were able to reduce scarring on the heart and induce a 50% improvement in overall heart function in mice that have undergone a heart attack.
SourceSanford Burnham Prebys·JournalNature Communications·DateMar 29, 2023
A new study found a protein that regulates macrophage function, clearing residues from regenerating muscle and recovering regenerative capacity in aged mice. The discovery holds promise for regenerative medicine and aging, potentially improving the success of current stem-cell based therapies.
SourceInstituto de Medicina Molecular·JournalNature Aging·TypeExperimental study·DateMar 23, 2023
Researchers have found a potential treatment for osteoarthritis by targeting the GP130 immune receptor, which causes hyper-inflammation in joints. The new compound R805/CX-011 showed promising results in animal studies, reducing joint pain and stiffness, and may lead to Phase 1 and 2A clinical trials.
SourceKeck School of Medicine of USC·JournalScience Translational Medicine·TypeExperimental study·DateMar 22, 2023
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers from Kessler Foundation found that transcutaneous spinal stimulation does not interfere with implanted intrathecal baclofen pump delivery systems. However, communication between the pump and its interrogator may be briefly affected due to electromagnetic interference.
SourceKessler Foundation·JournalFrontiers in Neuroscience·TypeExperimental study·DateMar 21, 2023
Researchers discovered that lipid deposition on medical implant surfaces can signal to the immune system whether to attack or ignore the implant. This knowledge could help develop biomaterials that deflect host immune aggression, reducing malfunction rates for devices like pacemakers and surgical mesh.
SourceRice University·JournalAdvanced Materials·TypeExperimental study·DateMar 14, 2023
Researchers at UIC hope to understand how the human immune system regulates lung tissue and develop new treatments for conditions like COPD and pulmonary fibrosis. The grant aims to create an infrastructure for collaboration among researchers studying lung endothelial cells and their role in inflammation.
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Researchers at Indiana University School of Medicine have identified a new type of cell called the vasculogenic fibroblast, which can help create new blood vessels for treatment. This discovery could lead to improved treatments for ischemic diseases such as diabetic wounds.
SourceIndiana University School of Medicine·JournalNature Communications·DateMar 1, 2023
A new cell therapy has demonstrated significant benefits in improving the heart's pumping ability and reducing the risk of cardiovascular death, heart attack, or stroke in patients with chronic heart failure. The therapy, using mesenchymal precursor cells (MPCs), also showed a strong signal in reducing inflammation and improving microv...
SourceTexas Heart Institute·JournalJournal of the American College of Cardiology·TypeRandomized controlled/clinical trial·DateFeb 27, 2023
Alejandro Sánchez Alvarado is awarded the Vilcek Prize in Biomedical Science for his groundbreaking work on regeneration. His research has significant implications for understanding cellular and organismal regeneration, with potential for further breakthroughs.
Researchers at UC San Diego develop new bioink with iodixanol, reducing light scattering and enabling high cell density printing. The technique creates functional human-like tissues with improved resolution and perfusion systems for long-term culture.
SourceUniversity of California - San Diego·JournalScience Advances·TypeExperimental study·DateFeb 22, 2023
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Researchers at Baylor College of Medicine investigated neural crest cell development to better comprehend and treat craniofacial birth defects. They discovered that changes in chromatin accessibility are regulated by the miR-302 microRNA family, which can be used to generate healthy cells for regenerating craniofacial defects.
SourceBaylor College of Medicine·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateFeb 16, 2023
Researchers have generated large-scale muscle-controlling nerve cells from ALS patients, revealing striking differences in gene expression between males and females. The study, published in Neuron, used over 450 lines of stem cells to create motor neurons that can potentially lead to the development of new therapeutics.
SourceCedars-Sinai Medical Center·JournalNeuron·DateFeb 9, 2023
Researchers at USC Keck School of Medicine have identified two new avenues for treating diverse forms of ALS by suppressing genes and inhibiting proteins. The findings suggest that targeting SYF2 gene suppression and PIKFYVE kinase inhibition may lead to broadly effective treatments for the disease.
SourceKeck School of Medicine of USC·JournalCell·DateFeb 7, 2023
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers at Rice University have developed a self-assembling peptide ink that enables the 3D printing of complex structures with cells, which can then be used to grow mature tissue in a petri dish. The ink allows for control over cell behavior using structural and chemical complexity.
SourceRice University·JournalAdvanced Materials·TypeExperimental study·DateFeb 7, 2023
Researchers have identified superfast muscles in mouse legs using new technology, opening up possibilities for therapeutic interventions to improve human limb movements. The discovery sheds light on the mechanisms behind fast twitch muscles and fatigue-resistant oxidative muscles.
SourceChinese Academy of Sciences Headquarters·JournalScience Advances·TypeExperimental study·DateFeb 5, 2023
Scientists at Duke-NUS Medical School and NHCS have discovered that blocking an immune-regulating protein called interleukin-11 enables damaged kidney cells to regenerate, restoring impaired kidney function. This breakthrough suggests a new approach for treating chronic kidney disease.
SourceDuke-NUS Medical School·JournalNature Communications·TypeExperimental study·DateFeb 2, 2023
The ISSCR 2023 Annual Meeting will showcase the year's most compelling stem cell research and clinical breakthroughs. Attendees can participate in dedicated poster sessions and interact with presenters.
SourceInternational Society for Stem Cell Research·DateJan 31, 2023
Scientists at Duke University have made a breakthrough in controlling gene expression in response to injury, using a segment of fish DNA called TREE. The method successfully targeted gene activity to specific regions and time windows, showing promise for regenerating damaged tissues in mammals.
SourceDuke University·JournalCell Stem Cell·TypeExperimental study·DateDec 13, 2022
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers at UCSF's Cell Design Institute engineered cells with customized adhesion molecules to form complex multicellular ensembles in predictable ways. The discovery represents a major step toward building tissues and organs through regenerative medicine.
SourceUniversity of California - San Francisco·JournalNature·DateDec 12, 2022
Researchers at The Forsyth Institute have made two breakthrough discoveries that could lead to new treatments for cartilage injuries and degeneration. They found that β-catenin, a multifaceted protein, plays a role in skeletal cell fate determination and ectopic chondrogenesis.
SourceForsyth Institute·JournalScience Advances·TypeExperimental study·DateNov 30, 2022
The USC+CHLA Alpha Clinic will advance clinical trials of new cell and gene therapies, engaging underserved communities and training the workforce that conducts them. This program complements existing efforts to translate discoveries into new therapies for better health outcomes.
Albert Almada's laboratory will explore the role of Nicotinamide Adenine Dinucleotide (NAD+) in muscle repair and regeneration. Lower levels of NAD+ may be inactivating stem cell repair, and re-activating it could promote better muscle healing in older animals.
The iPS Cell Stock Project has expanded its Japanese population coverage to 60% by using 27 cell stocks. These stocks were prepared from donors who are homozygous for human leukocyte antigens (HLA) A, B, and DR, increasing the likelihood of donor-patient matching.
SourceCiRA Foundation·JournalMed·TypeCommentary/editorial·DateNov 16, 2022
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers at Indiana University School of Medicine developed a minimally invasive nanochip device that can reprogram tissue function by delivering specific genes. The technology has shown promise as a treatment for traumatic muscle loss, with improved muscle function observed in rats following volumetric muscle loss.
SourceIndiana University·Journalnpj Regenerative Medicine·TypeExperimental study·DateNov 9, 2022
Researchers have discovered a way to reactivate a fetal repair pathway in adults to improve healing of diabetic wounds. The study used tissue nanotransfection technology to deliver a gene that activates the protein NPGPx, which is active in fetuses but largely inactive in adults and absent in diabetic adults.
SourceIndiana University School of Medicine·JournalMolecular Therapy·DateNov 2, 2022
The Alpha Stem Cell Clinic will develop preclinical studies into early and later phase clinical trials with the goal of establishing advanced regenerative medicine treatments. The clinic will also foster greater collaboration with eight similar clinics across the state and educate the public about stem cell and related therapies.
Researchers found that adult heart cells have fewer communication pathways called nuclear pores, which may protect against harmful signals but prevent regeneration. This discovery sheds light on why adult hearts do not regenerate like newborn mice and human hearts.
SourceUniversity of Pittsburgh·JournalDevelopmental Cell·TypeExperimental study·DateOct 24, 2022
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers from Yokohama National University successfully generated hair follicles in cultures using organoid cultures. The study demonstrates the potential of hair follicle organoids for understanding hair follicle development and regeneration, as well as evaluating drugs for treating hair loss disorders.
SourceYokohama National University·JournalScience Advances·DateOct 21, 2022
Ruben van Boxtel's research focuses on understanding the origins of late treatment effects in children with blood cancer, exploring the role of stem cells. His work aims to find solutions to prevent these effects and predict their likelihood.
SourcePrincess Máxima Center for Pediatric Oncology·DateOct 18, 2022
The Vilcek Foundation has awarded $250,000 in prizes to four leading immigrant scientists: Alejandro Sánchez Alvarado, Edward Chouchani, Biyu J. He, and Shixin Liu. They received the 2023 Vilcek Foundation Prizes in Biomedical Science for their groundbreaking work in regeneration, metabolic disease, cognitive neuroscience, and nanoscal...
The USC COMPASS program aims to recruit and support students from historically underrepresented backgrounds to pursue careers in regenerative medicine. Scholars will receive a minor in Stem Cell Biology and Regenerative Medicine, as well as paid summer internships and mentorship opportunities.
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers aim to develop scalable, modular manufacturing platform for growing new tissues from component parts, accelerating their fabrication and use. The goal is to assemble functional constructs that restore or improve damaged tissues or whole organs.
Researchers discovered that macrophages eliminate stressed stem cells with high levels of reactive oxygen species, while healthy cells are amplified. The study found that a specific marker, calreticulin, acts as an 'eat me' signal for stressed cells.
SourceBoston Children's Hospital·JournalScience·DateSep 27, 2022
Researchers at NUS have developed a method to produce cell-based meat using magnetic pulses, reducing reliance on animal products and increasing efficiency. This technology has the potential to revolutionize the food industry and improve regenerative medicine by stimulating the growth of healthy cells.
SourceNational University of Singapore·JournalBiomaterials·TypeExperimental study·DateSep 25, 2022
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
A study by Kyoto University Professor Misao Fujita found that Japan's Act on the Safety of Regenerative Medicine lacks key provisions to prevent unproven treatments from being administered to patients. The lack of scientific verification and clear definitions for medical innovations and interventions are major concerns.
SourceKyoto University·JournalCell Stem Cell·TypeMeta-analysis·DateSep 13, 2022
Researchers from UMass Amherst have created a tiny sensor that can simultaneously measure electrical and mechanical cellular responses in cardiac tissue. This breakthrough device has the potential to lead-edge applications in cardiac-disease experiments and improve health monitoring for cardiac disease studies.
SourceUniversity of Massachusetts Amherst·JournalScience Advances·TypeExperimental study·DateAug 24, 2022
Researchers at RIKEN have discovered how marsupials' hearts can regenerate for several weeks after birth, allowing for potential treatment of human heart disease. They found that inhibiting a protein called AMPK extended the period of regeneration in both mice and opossums, with minimal scarring.
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
A new study successfully introduces healthy photoreceptor cells derived from stem cells into the retinas of dogs, marking significant progress toward a cell-based therapy for blindness. The treatment enables cells to survive and form connections with existing retinal cells, paving the way for a regenerative medicine approach.
SourceUniversity of Pennsylvania·JournalStem Cell Reports·TypeExperimental study·DateJul 28, 2022