Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
A new study published in Fertility and Sterility found that underlying subfertility may account for some of the risks associated with assisted reproductive technology (ART) births. Singletons born to mothers with ART had higher rates of preterm birth and low birth weight, while twins had better outcomes.
Researchers at Johns Hopkins have developed a conceptual model defining three sources of patient dignity: shared humanity, personal narrative, and autonomy. The study identifies four consensus areas relevant to treatment with respect and dignity in the ICU, including treating patients as human beings, unique individuals, and entitled t...
A study of 250 patients with displaced proximal humeral fractures found no significant differences between surgical and nonsurgical treatments in patient-reported outcomes over two years. The researchers concluded that these results do not support the trend of increased surgery for patients with this type of fracture.
Research highlights benefits of screening, identifying 5.8 million men with unknown heart risk factors over 20 years and avoiding 1.1 million cardiovascular events, saving $28 billion.
A new collaborative care model for ICU survivors decreases serious illness likelihood after discharge and improves quality of life, reducing post-ICU syndrome symptoms. The Critical Care Recovery Center provides patient-centered care to address functional impairments and disorders.
Despite being discredited, interventions like Facilitated Communication remain widely used in the autism community due to emotional appeal and a desire for quick fixes. Experts emphasize the need for better education on effective treatments and caution against false hope.
A new approach to tackling alphavirus infections has been developed using the protein pentraxin 3, which plays a crucial role in promoting virus infection and disease. This breakthrough discovery paves the way for improved vaccine and drug development.
A new study led by USC Eye Institute finds that ranibizumab may help reduce cases of blindness by 75 percent among Hispanic and non-Hispanic whites with diabetic macular edema. The treatment could potentially save the sight of thousands of working-age individuals suffering from diabetic eye disease.
A two-year study found that soldiers receiving cognitive-behavioral therapy were 60 percent less likely to make a suicide attempt than those receiving standard treatment. The therapy focused on managing stress and thinking in more helpful ways.
A new study by Loyola University Medical Center shows that using high-fidelity patient simulators can significantly improve the knowledge, skills, and confidence of first-year neurology residents. The study found a 16.1% improvement in multiple-choice tests about treating stroke patients.
Researchers have developed a new device that significantly improves healing of small ruptured brain aneurysms. The HydroCoil device combines a gel-like substance with a platinum coil, allowing it to expand and block blood flow to the aneurysm, reducing recurrence rates by up to 70% compared to standard treatment.
A landmark study published in the New England Journal of Medicine shows a dramatic improvement in restoring blood flow to the brain after adding stent thrombectomy to standard clot-dissolving therapy. The new treatment restores blood flow to 89% of patients, with 71% returning to independent living.
A new study found that supplementary feeding for 12 weeks makes an impact, but treating children until they reach target weights and arm circumference is more important. Raising these targets could significantly lower the rate of relapse.
Researchers from Marcus Autism Center found intensive behavioral intervention to be effective in eliminating pica in children with autism spectrum disorder. The treatment involved blocking inappropriate eating, redirecting behavior, and rewarding disposal of non-edible objects, resulting in a 96% reduction in pica in most cases.
Commercial antibodies used in research often fail to function properly, but DNA technology can solve this problem by producing high-quality antibodies. The authors advocate for the use of recombinant DNA technology to improve reproducibility and reduce waste in biological science.
Researchers from Texas A&M University have discovered a compound called resveratrol that may help improve memory function in older adults. Studies have shown that treatment with resveratrol can increase neurogenesis and improve blood flow to the brain, leading to better cognitive function.
A new study found that surgical treatment provides significant benefit for lumbar spinal stenosis and degenerative spondylolisthesis in patients over 80, with comparable complication rates to younger patients. The benefits of surgery were similar to those in younger patients, except for pain and physical function outcomes.
A recent study by scientists at the University of Granada and the High Resolution Hospital in Loja reveals a moderate relation between asthma control and xerostomia severity. Inhaled corticosteroids (ICs) used to treat asthma can lead to dry mouth syndrome, which affects quality of life and mouth health.
The study analyzed 11,535 women with preterm birth in the first pregnancy and found that an interval of less than 12 months increases the risk for severe preterm birth. Women with preterm birth are advised to postpone their next pregnancy for at least 12 months.
Researchers discovered that a low-energy nanosecond laser therapy can reverse the pathological and molecular changes in age-related macular degeneration. The treatment does not cause retinal damage, and it may also be effective on other eye diseases like diabetic macular oedema.
Researchers found that interacting with a nurse, watching a DVD, or using stress balls reduced anxiety by 25-30% and pain by 16-22%. Simple distraction techniques can significantly improve patient experience and may be used for other operations without general anesthesia.
Researchers argue that reliable information is hard to identify among growing medical care advertisements online, potentially influencing patients' decisions. They recommend clearly labeling hospital websites as advertisements and allocating resources to create balanced online informational tools.
Full implementation of new guidelines could prevent 56,000 cardiovascular disease events and 13,000 deaths annually, with cost-effectiveness found in treating stage 1 hypertension for some patients. Treating women ages 35-44 with stage 1 hypertension without CVD may not be cost-effective.
Sexual offending treatment programs in prisons and hospitals have been shown to be ineffective in reducing recidivism rates, with most offenders releasing back into society posing the same level of risk as before treatment. Experts argue that only proven treatments should be used to rehabilitate offenders effectively.
Grand Challenges Canada funds BasicNeeds' award-winning model for mental health treatment in resource-poor countries, enabling access to care for nearly 75% of the world's people with mental illness. The model generates sustainable impact, enabling 86% of people with mental health problems to access treatment and report reduced symptoms.
Researchers have developed a treatment that extends telomeres in human cells, which could lead to longer and healthier lives. The treatment uses modified mRNA encoding TERT, resulting in rapid lengthening of telomeres and increased cell division capacity.
A study found that transoral fundoplication was more effective in eliminating troublesome regurgitation than omeprazole in patients with persistent GERD symptoms. The procedure showed a lower failure rate and better safety profile compared to traditional surgery, making it a promising treatment option.
A new checklist from Australian doctors aims to prompt frank discussions about end-of-life care and minimize futile treatments. The CriSTAL tool assesses 29 predictors of death in elderly patients, helping healthcare professionals recognize the inevitability of death and provide more appropriate services.
The use of ICSI in IVF procedures for male infertility has doubled between 1996 and 2012. Despite this increase, studies found no association with improved reproductive outcomes such as implantation or pregnancy rates.
A new study found that postpartum depression can have onset of symptoms that begin in pregnancy, impacting prognosis and treatment tailoring. Women who experienced symptoms during pregnancy may be at risk for more severe postpartum depression.
A new study shows that cold atmospheric pressure plasma significantly reduced the number of virus particles in norovirus samples, making it a promising method for continuous disinfection of contaminated surfaces. The technology is environmentally friendly and effective against viruses with high tenacity, like noroviruses.
A study in the Journal of Clinical Investigation found that UCP2 induces fatty acid synthesis, activating inflammatory pathways in patients with sepsis. Lack of UCP2 improved survival in a mouse model of sepsis, suggesting UCP2 as a potential therapeutic target.
Patients with low illness acceptance have lower energy, more severe pain, and negative emotional reactions, leading to social isolation. Acceptance of illness is crucial for effective treatment and improved daily functioning.
A recent study published in HortScience suggests that nitrogen from reclaimed water can support optimal turfgrass growth. The researchers found that turfgrass responded positively to higher concentrations of nitrogen in the irrigation water, but the concentration needed was at least 5 mg·L−1.
A University of Michigan study found a 92% increase in children seeking medical assistance for concussions in states with concussion laws. The legislation, combined with heightened public awareness, has led to significant increases in concussion treatment rates among school-age athletes.
Scientists are exploring how bitter compounds cause airway constriction and searching for potential new treatments using a slime mould model. The study aims to identify cellular mechanisms that could reverse or prevent asthma attacks.
A groundbreaking study found that the Los Angeles LGBT Center's voter persuasion methods reduced anti-gay prejudice and may have potential to reduce other forms of prejudice. The approach, involving one-on-one conversations, had a long-lasting impact on changing conservative voters' minds.
A new case study assesses the immediate and ongoing response to the 9/11 disaster, identifying key elements that impact the health of exposed populations. The study emphasizes the importance of clinical expertise, site safety, attention to vulnerable populations, and developing trust and transparency in public health disaster response.
A new study by University at Buffalo Research Institute on Addictions found that smoking is associated with difficulties in alcohol treatment. Tobacco smokers had shorter treatment durations and were less likely to achieve their alcohol-related goals compared to non-smokers.
A study published in JAMA Ophthalmology found that teleophthalmology did not result in worse visual outcomes, even though it led to longer wait times for treatment reinitiation. The teleophthalmology approach was cost-effective and reliable for patients with another eye disease, diabetic retinopathy.
A new computer-based approach to treating anxiety sensitivity has shown significant results in reducing suicide risk. The Cognitive Anxiety Sensitivity Treatment (CAST) is a 45-minute online program that provides interactive features and exercises to improve responses to stress and anxiety.
Scientists have developed a novel approach to treating asthma by targeting the trigger - dust mite allergens. The newly created compound significantly dampened immune responses in rats exposed to various allergens, suggesting a potential breakthrough in asthma treatment.
A new study found that patients with spinal compression fractures who wore no brace fared as well as patients instructed to wear a brace for treatment, with comparable outcomes in terms of pain and healing. However, prolonged use of the braces may result in muscle deterioration, skin irritation, and additional costs.
A bottlenose dolphin with breathing difficulties underwent pioneering therapeutic bronchoscopy, marking the first time such a procedure was performed on a marine mammal. The dolphin's respiratory cycle improved significantly after the treatment, and she returned to her normal behavior.
Drs. Alim Louis Benabid and Mahlon DeLong developed deep brain stimulation (DBS) for treating Parkinson's disease, improving motor function and quality of life for thousands of patients. Their groundbreaking research has led to the use of DBS in other disorders, benefiting over 110,000 patients worldwide.
A new long-term clinical trial found that Lung Volume Reduction Coil treatment is safe over a 3-year period. Half of the patients showed continued improvement in lung function capacity and overall quality of life.
A recent study by Lund University found that group mindfulness treatment is as effective as individual cognitive behavioral therapy (CBT) in treating depression and anxiety. The study included 215 patients and showed significant reductions in symptoms of both conditions, regardless of the treatment approach.
The study aims to compare VR-based balance treatment with traditional methods for rehabilitating balance dysfunction after TBI. It will evaluate the effectiveness of customizing VR exercises based on individual ability levels and assess dual-task VR training for improving balance.
Researchers from UT Southwestern Medical Center found a strong, protective relationship between cholesterol efflux and cardiovascular risk. The study revealed that measuring cholesterol efflux provides significantly different information than traditional HDL cholesterol levels.
Researchers at University of Melbourne developed a new laser treatment that improves eye health in AMD patients by reducing disease signs and enhancing supporting cells. The nanosecond laser does not cause damage to the retina, raising hope for monocular treatment options.
A new study analyzes individual results and population-level data to clear the paradox of faster heart attack treatment times. The findings show that treating more complex patients with emergency angioplasty and stents appears to be why mortality hasn't decreased with reduced door-to-balloon time.
Case Western Reserve researchers develop a procedure that restores breathing function in paralyzed muscles even after a year of injury. The treatment approach combines enzyme injection and intermittent hypoxia therapy to boost serotonin levels, reactivating the diaphragm and restoring normal breathing.
A clinical trial found that hyperbaric oxygen treatment did not improve postconcussion symptoms in military members, but both the treatment and sham groups showed improvements compared to those who received no supplemental air chamber treatment. The study suggests that the observed improvements may be due to placebo effects.
A specialized ambulance staffed with a neurologist and equipped with a computed tomographic scanner increased the percentage of stroke patients receiving thrombolysis within the golden hour, reducing time to treatment by 24.5 minutes. This approach improved short-term outcomes without increasing risks for mortality.
A new study by Hospital for Special Surgery found that total hip replacement is an excellent option for young JIA patients, with 85% of patients experiencing at least 10 years of implant longevity. Patient-reported outcomes showed favorable results in terms of activities of daily living and pain management.
A new study of over 12,000 Danish patients with hip fractures found that those treated in smaller hospital departments had a lower mortality rate and shorter length of stay. The quality of care was also higher in these departments compared to larger ones.
A new study by RAND Corporation found that most community-based mental health providers lack the necessary training to address the specific needs of military veterans. The survey of 522 mental health providers revealed that only 13% met criteria for cultural competency and delivering evidence-based care.
Researchers developed a family-focused, culturally-informed treatment for schizophrenia that reduced patients' psychiatric symptoms and improved caregiver emotional well-being. The program tapped into the family's cultural beliefs, values, traditions, and religious practices to help them manage the illness.
A new study has identified genetic material that recognizes early stages of infection in patients with hemorrhagic fevers, such as Lassa and Marburg viruses. This discovery could lead to the development of better diagnostics and improved treatment outcomes.
Research suggests that hospital interventions can significantly reduce smoking rates, with around 14.5% of hospital admissions being smokers. Implementing routine smoking cessation support could prevent hundreds of thousands of premature deaths.