Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
Research reviews suggest that individuals with cognitive impairment, including dementia and Alzheimer's disease, exhibit altered pain processing. This is often accompanied by increased sensitivity to painful stimuli, making effective diagnosis and treatment challenging due to communication difficulties.
A new study from Iran recommends treatments of hot water with calcium to extend storage life and improve quality in kiwifruit. The research evaluated the effect of hot water combined with Ca solution treatments on qualitative characteristics of kiwifruit during cold storage, showing that these treatments significantly suppressed color ...
A study published in BMC Family Practice reveals that South Asian individuals with diabetes often struggle due to conflicting views on the causes of their condition. However, strong family support networks can help manage the disease, highlighting the need for culturally sensitive treatment plans and education guidelines.
Researchers developed a novel method to measure injectable wrinkle reducer efficacy using 3D imaging. The technique, called speckle tracking photogrammetry, allows for objective evaluation of wrinkle reduction and optimal dosage. It has the potential to guide physician and consumer choice in individual cases.
Researchers discovered two distinct types of nervous systems in the respiratory circuit, one for upper airway sensations and another for lower lung region emotions. This breakthrough may lead to new treatments for cough hypersensitivity and related respiratory diseases.
Recent clinical trials demonstrate significant improvements in neurological function with clot retrieval therapies, increasing recovery rates to 40-50%. However, implementation into practice requires concentrated effort from multiple parties, including training and education.
A new method of oxygen delivery, high-flow nasal oxygen therapy, was found to be non-inferior to traditional noninvasive ventilation in treating postoperative respiratory failure. The study compared outcomes between 830 patients who received either high-flow nasal oxygen therapy or bilevel positive airway pressure.
The new guidelines emphasize the importance of early and intensive communication between healthcare teams and families to prevent conflicts. In cases where disputes remain unresolvable, a fair process of dispute resolution involving expert consultants and mediation is recommended.
Kobe University has developed a mercury-free film-type ultraviolet light source for medical applications, which can deliver high-intensity radiation to only the affected area, reducing treatment time and patients' stress. The technology uses plasma excitation similar to plasma televisions and is expected to begin sales in October 2015.
The Hong Kong Polytechnic University has developed a novel computer-aided detection system for acute stroke using computer intelligence technology. The system detects ischemic and hemorrhagic strokes with 90% accuracy, providing timely treatment within the golden hour of stroke onset.
Research published in the Journal of the American Heart Association found that long-term depression can increase stroke risk in adults over 50, with risks remaining even after symptoms subside. The study of 16,178 participants showed that those with high depressive symptoms had a higher risk of first-time stroke.
A study led by Plymouth University shows that offenders enrolled in alcohol treatment programmes are significantly less likely to be charged or reconvicted. The programmes reduced reoffending rates by 50%, with cognitive behavioural therapy proving most effective.
A new transgenic nonhuman primate model of Huntington's disease has been developed, showing similarity to humans in progressive neurodegeneration and motor control decline. The study reveals cognitive and motor impairments emerging at 16 months of age, and dystonia and signs of neurodegeneration on brain imaging at 24 months.
A new model systematically evaluates malaria treatment programs in multiple countries, finding no country shows reductions in malaria treatment associated with testing as hypothesized. Contextual factors such as access to care and stockouts largely explain the variation in program experiences.
The UK is launching a Choosing Wisely programme to tackle overdiagnosis and unnecessary care, following a US initiative. The programme aims to promote evidence-based care by identifying tests and procedures with no benefit, and reducing waste in healthcare.
A literature review analyzing the most frequently cited papers on lumbar spine surgery identified key trends and observations, including studies highlighting situations where spinal surgery should not be performed. The top-ranked paper was a classic study showing common spinal abnormalities despite no back pain or symptoms.
A study published in Psychiatry Research found that Iraq and Afghanistan veterans who engaged in non-suicidal self-injury were five times more likely to attempt suicide. The research suggests that NSSI could serve as a marker for identifying veterans at high risk of suicide.
Analysis of seven electronic databases reveals frequent users account for up to one in 12 patients seeking emergency department care, and are around 2.5 times more likely to be admitted or require outpatient treatment. The study suggests that frequent users may benefit from targeted proactive approach.
Researchers developed a combination approach to recover phosphorus from wastewater using mathematical modeling. The method achieved approximately 90% removal of phosphorus, generating $150,000 in annual revenue for WWTPs with limited budgets. This sustainable approach reduces mining demand and improves surface water health.
Researchers at Wayne State University are seeking to understand the genomic information of herpes simplex virus 1 and its interactions with host cells to develop new anti-herpes treatments. The study aims to uncover the functions of infected cell protein 0, which plays a key role in disrupting host defenses.
Researchers have characterized early-stage changes in Alzheimer's-affected cells, revealing that even a small number of affected cells can cause widespread electrical activity disruption. This could lead to the development of new diagnostic methods, including electroencephalogram screening.
A RAND Corporation study found that online training programs can be as effective as in-person instruction in teaching psychotherapists evidence-based treatments. The approach may speed up the adoption of new treatments and improve patient outcomes by providing an efficient and scalable way to train large numbers of clinicians.
A new psychological technique called Motivational Interviewing has been shown to help smokers change their behavior and see tobacco as unpleasant. This technique, which takes just 20 minutes, increases self-efficiency and reduces resistance, allowing smokers to overcome motivation barriers.
The BMJ urges the next Health Secretary to prioritize sustainable funding, collaboration, and transparent governance to secure the NHS's future. The service is stretched close to breaking point due to flat-line funding, aging population demands, and social care cuts.
Researchers at Ben-Gurion University of the Negev are developing a new urban water program, focusing on water-sensitive cities and innovative technologies to deliver water security. The program aims to improve urban climates, reduce carbon footprints and enhance quality of life.
A high-dose treatment of sodium nitrite with citric acid was found to be more effective in clearing up anogenital warts compared to lower doses or a placebo. The study showed a dose-related increase in side effects, but the optimal dose is considered to be the current one.
Researchers at UC Davis have identified the biochemical underpinnings of Canavan disease, a type of leukodystrophy that causes progressive neurological deterioration. By blocking the production of NAA, they aim to find a promising direction for treatment and potentially reverse the process in children with the disease.
A large-scale study published in the New England Journal of Medicine found that therapeutic hypothermia did not improve neurological outcomes in pediatric cardiac arrest patients. The study compared two treatment groups: therapeutic hypothermia and active normothermia therapy.
A Phase 3 study demonstrates that sofosbuvir in combination with ribavirin and peginterferon is highly effective for treating genotype-3 HCV-infected patients, particularly those with cirrhosis. The BOSON study shows the optimal duration of treatment for these patients, which could lead to improved outcomes.
A large-scale study showed that emergency body cooling does not improve survival rates or reduce brain injury in infants and children with out-of-hospital cardiac arrest. Therapeutic hypothermia, however, has been shown to be effective for adults and newborns after cardiac arrest.
A study published by the European Association for the Study of the Liver found that silymarin, derived from milk thistle, can resolve non-alcoholic steatohepatitis (NASH) and improve fibrosis in patients. The results suggest a potential new treatment option for this condition.
Researchers found that delaying treatment until after a patient's FIB4 level exceeds 3.25 has a clear detrimental effect on treatment effectiveness, increasing morbidity and mortality risks. Early treatment initiation is crucial to prevent adverse outcomes.
A pooled analysis of data from two randomized trials confirms vitamin E as an effective treatment for non-alcoholic steatohepatitis (NASH), with significant improvements in liver histology and disease resolution. The study supports the use of vitamin E as a safe and effective solution for both adults and children with NASH.
Patients with newly diagnosed and treated osteoporosis have an increased life expectancy of 15-26 years, depending on age and gender. Long-term management of osteoporosis is crucial to ensure optimal patient outcomes.
A trial conducted in Catalonia, Spain, found that removing blood clots from large brain blood vessels improved function and reduced disability after stroke. The technique, called endovascular therapy or stent retriever thrombectomy, showed a 1.7 fold reduction in disability compared to medical intervention alone.
The new guidelines provide information on preventing and treating venous thromboembolism (VTE) during pregnancy, birth, and postpartum. Women with risk factors should undergo thorough assessment and be offered prophylactic treatment to reduce the risk of VTE.
A new tool has been developed to improve dementia care for south Asian people, addressing cultural barriers to diagnosis. The adapted BEMI-C tool takes into account sensitivities that can act as barriers to effective diagnosis and treatment.
A new review emphasizes the psychological impact of infertility and the need for healthcare professionals to consider emotional well-being. Counselling plays a critical role in providing comprehensive care, integrating medical and mental health aspects.
Researchers at University of Queensland found Botox toxin travels through nerves to central nervous system, where it can intoxicate neighboring cells. This discovery has implications for disease treatments and raises questions about the toxin's long-term effects.
A study published in PLOS Medicine proposes a multi-stage approach to testing Ebola treatments, which may be quicker than traditional randomized trials while still providing robust results. This alternative design could potentially triage treatments faster and recommend them without further RCTs under certain circumstances.
A survey of 1,095 adults found that patients prefer simple explanations and doctor queries over burdensome consent regulations. The study's findings will inform US Office of Human Research Protections and FDA regulations on patient permissions for research conducted during clinical care.
A new study suggests Richard III kept his severe scoliosis hidden until his death in 1485, controlled by the king's body image and posthumous reputation. The treatment of his dead body after the Battle of Bosworth is linked to his later historical and literary reputation as 'Crookback Richard'.
Researchers developed a high-sensitivity cardiac troponin T algorithm to rule out and rule-in heart attacks in emergency departments. The study found that the new strategy accelerated management of patients with suspected acute MI by allowing safe rule-out and accurate rule-in in 3 out of 4 patients.
Researchers at Kyoto University discovered how nerve cells adjust to low energy environments during brain growth, shedding light on neurodegenerative disorders. They found two protein molecules that produce enzymes to allocate energy molecules for cellular survival in areas with low ATP energy concentrations.
A comparison study found that IVFpredict is more accurate than the Templeton method in predicting the chances of successful live births after IVF treatment. The study analyzed data from 130,960 IVF cycles and showed that both models underestimated live birth rates, but IVFpredict remained more accurate.
Osteoporosis-related fractures in China are expected to double by 2035, with costs rising to approximately US$25.58 billion by 2050. The study also found that women account for 73% of total costs, sustaining three times more fractures than men.
Research from San Francisco State University reveals that fertility treatment patients are more likely to experience major depressive disorder (MDD) than the general population. A key factor in predicting a patient's risk is whether they have a previous diagnosis of MDD, which is often overlooked by healthcare providers.
A study published in Diabetologia found that spending more time watching TV daily increases the risk of developing diabetes by 3.4%. The research used data from participants in the Diabetes Prevention Program, which showed a reduction in sitting behavior despite the absence of specific goals aimed at reducing it.
A study published in The Journal of Nervous and Mental Disease found that 'religiously integrated' cognitive-behavioral therapy is at least as effective as conventional CBT for treating major depression in chronically ill patients. Highly religious patients showed greater improvement with this approach.
A new study reveals that adults treated with ECMO have better survival rates when cared for at hospitals that use the treatment frequently. The research analyzed data from over 56,000 patients across 290 hospitals worldwide, finding significant variation in survival rates between centers.
New research reveals that spinal surgery significantly reduces low back pain and improves sexual function in patients with degenerative conditions. The study found that 70% of patients consider sex an important aspect of their life quality.
The FARE Investigator in Food Allergy Awards support early and mid-career researchers expanding scientific understanding of food allergy through education and basic and clinical research. Recipients include Jessica O'Konek and Duane Wesemann, who will investigate nanoemulsion-based vaccines and the influence of microbial exposures on p...
A new study from the University of Alberta's Faculty of Medicine & Dentistry found that keeping a pain diary can have unintended consequences on patient recovery. Patients who kept diaries had slower recovery rates compared to those who did not.
Residents who walked near newly greened vacant lots had significantly lower heart rates compared to walking near blighted, or neglected, vacant lots. The average heart rate reduction was over 5 beats per minute lower when near greened lots versus non-greened lots.
A single oral dose of azithromycin has shown promising results in eliminating yaws from Papua New Guinea, with an 83.8% success rate among infected residents. To achieve global eradication, Kazura advocates for improved infrastructure, mapping systems, and community commitment.
Researchers have identified over 300 proteins in the uterus that can increase IVF success rates. By boosting or reducing these protein levels, embryos may implant more successfully. The study provides new insights into fertility treatments and could lead to improved IVF outcomes.
Continuous bioprocessing is gaining consideration as a method of industrial bioprocessing, with potential advantages including lower costs and increased efficiency. Dr. Konstantin Konstantinov and Dr. Charles Cooney emphasize the need for methods to evolve around this new platform.
The American College of Physicians recommends avoiding cardiac screening in low-risk adults, citing lack of benefits and potential harms. Instead, physicians should focus on treating modifiable risk factors such as smoking, diabetes, and hypertension.
Immediate treatment of HCV-infected patients with moderate or advanced liver scarring is cost-effective, and can also be effective in those with minimal or no scarring. This finding increases the potential for quality of life improvement, particularly when lower treatment costs are assumed.
Research shows that CT scans paired with standard care lead to more accurate diagnoses of coronary artery disease, altering follow-up testing and treatments. This results in a lower incidence of heart attacks among patients receiving the test compared to those receiving usual care.